[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100547974":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":11,"centralContacts":33,"locations":37,"responsibleParty":612,"collaborators":11,"id":614,"slug":615,"hasResults":616,"nctId":617,"briefTitle":618,"officialTitle":619,"acronym":620,"eligibilityCriteria":621,"healthyVolunteers":616,"sex":622,"minAge":623,"maxAge":11,"enrollmentInfo":624,"targetDuration":11,"studyType":627,"phases":628,"briefSummary":630,"conditions":631,"keywords":11,"overallStatus":54,"whyStopped":11,"lastUpdateSubmitDate":634,"lastUpdatePostDateStruct":635,"startDateStruct":638,"completionDateStruct":640,"leadSponsor":642,"locationsCount":643},{"fullName":5,"class":6},"NMD Pharma A\u002FS","INDUSTRY",[8,14,17,20],{"label":9,"type":10,"description":11,"interventionNames":12},"NMD670 high dose","EXPERIMENTAL",null,[13],"Drug: NMD670",{"label":15,"type":10,"description":11,"interventionNames":16},"NMD670 mid dose",[13],{"label":18,"type":10,"description":11,"interventionNames":19},"NMD670 low dose",[13],{"label":21,"type":22,"description":11,"interventionNames":23},"Placebo","PLACEBO_COMPARATOR",[24],"Drug: Placebo",[26,31],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":11},"DRUG","NMD670","Tablets taken twice a day for 21 days",[9,18,15],{"type":27,"name":21,"description":29,"armGroupLabels":32,"otherNames":11},[21],[34],{"name":5,"role":35,"phone":36,"phoneExt":11,"email":36},"CONTACT","contact@nmdpharma.com",[38,52,70,87,103,119,136,153,170,185,202,219,229,246,260,277,291,305,318,329,339,344,349,366,381,396,411,423,438,454,469,485,502,517,532,544,557,572,582,596],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":11},"Profound Research LLC","WITHDRAWN","Carlsbad","California","92011","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-117.35059,33.15809,{"lat":50,"lon":49},{"facility":53,"status":54,"city":55,"state":42,"zip":56,"country":44,"countryCode":45,"cosmosGeoPoint":57,"geoPoint":61,"contacts":62},"University of California Irvine Medical Center","RECRUITING","Irvine","92868",{"type":47,"coordinates":58},[59,60],-117.82311,33.66946,{"lat":60,"lon":59},[63,67],{"name":64,"role":35,"phone":65,"phoneExt":11,"email":66},"Siddhant Partap","650-224-2637","spratap1@hs.uci.edu",{"name":68,"role":69,"phone":11,"phoneExt":11,"email":11},"Ali Amer Habib","PRINCIPAL_INVESTIGATOR",{"facility":71,"status":54,"city":72,"state":73,"zip":74,"country":44,"countryCode":45,"cosmosGeoPoint":75,"geoPoint":79,"contacts":80},"University of Colorado Neuromuscular Division","Aurora","Colorado","80045",{"type":47,"coordinates":76},[77,78],-104.83192,39.72943,{"lat":78,"lon":77},[81,85],{"name":82,"role":35,"phone":83,"phoneExt":11,"email":84},"Alexis Shepardson","303-724-4644","neuroresearch@cuanschutz.edu",{"name":86,"role":69,"phone":11,"phoneExt":11,"email":11},"Stacy Dixon, MD",{"facility":88,"status":54,"city":89,"state":90,"zip":91,"country":44,"countryCode":45,"cosmosGeoPoint":92,"geoPoint":96,"contacts":97},"SFM Clinical Research, LLC","Boca Raton","Florida","33487",{"type":47,"coordinates":93},[94,95],-80.0831,26.35869,{"lat":95,"lon":94},[98,101],{"name":99,"role":35,"phone":100,"phoneExt":11,"email":11},"Gabrielle DeMaria","(561) 939-0333",{"name":102,"role":69,"phone":11,"phoneExt":11,"email":11},"Marc Feinberg, MD",{"facility":104,"status":54,"city":105,"state":90,"zip":106,"country":44,"countryCode":45,"cosmosGeoPoint":107,"geoPoint":111,"contacts":112},"Neuromuscular Research Division | University of South Florida","Tampa","33612",{"type":47,"coordinates":108},[109,110],-82.45843,27.94752,{"lat":110,"lon":109},[113,117],{"name":114,"role":35,"phone":115,"phoneExt":11,"email":116},"Jessica Shaw","813-974-9413","jessshaw@usf.edu",{"name":118,"role":69,"phone":11,"phoneExt":11,"email":11},"Tuan H Vu",{"facility":120,"status":54,"city":121,"state":122,"zip":123,"country":44,"countryCode":45,"cosmosGeoPoint":124,"geoPoint":128,"contacts":129},"Augusta University, Neuroscience Center","Augusta","Georgia","30912",{"type":47,"coordinates":125},[126,127],-81.97484,33.47097,{"lat":127,"lon":126},[130,134],{"name":131,"role":35,"phone":132,"phoneExt":11,"email":133},"Brandy Quarles","706-721-0390","neuromuscular_research@augusta.edu",{"name":135,"role":69,"phone":11,"phoneExt":11,"email":11},"Michael Rivner",{"facility":137,"status":54,"city":138,"state":139,"zip":140,"country":44,"countryCode":45,"cosmosGeoPoint":141,"geoPoint":145,"contacts":146},"NextGen Precision Health","Columbia","Missouri","65212",{"type":47,"coordinates":142},[143,144],-92.33407,38.95171,{"lat":144,"lon":143},[147,151],{"name":148,"role":35,"phone":149,"phoneExt":11,"email":150},"Neetha Gali","(573) 882-3065","ngdcd@health.missouri.edu",{"name":152,"role":69,"phone":11,"phoneExt":11,"email":11},"David Arnold",{"facility":154,"status":54,"city":155,"state":156,"zip":157,"country":44,"countryCode":45,"cosmosGeoPoint":158,"geoPoint":162,"contacts":163},"The University of North Carolina at Chapel Hill","Chapel Hill","North Carolina","27599",{"type":47,"coordinates":159},[160,161],-79.05584,35.9132,{"lat":161,"lon":160},[164,168],{"name":165,"role":35,"phone":166,"phoneExt":11,"email":167},"Manisha Chopra","1-919-843-7857","chopram@neurology.unc.edu",{"name":169,"role":69,"phone":11,"phoneExt":11,"email":11},"James Howard",{"facility":171,"status":54,"city":172,"state":173,"zip":174,"country":44,"countryCode":45,"cosmosGeoPoint":175,"geoPoint":179,"contacts":180},"The Ohio State University","Columbus","Ohio","43221",{"type":47,"coordinates":176},[177,178],-82.99879,39.96118,{"lat":178,"lon":177},[181],{"name":182,"role":35,"phone":183,"phoneExt":11,"email":184},"Lischele Watkins,, MACPR","614-293-1737","Lischele.Watkins@osumc.edu",{"facility":186,"status":54,"city":187,"state":188,"zip":189,"country":44,"countryCode":45,"cosmosGeoPoint":190,"geoPoint":194,"contacts":195},"University of Oregon","Portland","Oregon","97239",{"type":47,"coordinates":191},[192,193],-122.67621,45.52345,{"lat":193,"lon":192},[196,200],{"name":197,"role":35,"phone":198,"phoneExt":11,"email":199},"Katie Lewis","503-494-5236","lewiskat@ohsu.edu",{"name":201,"role":69,"phone":11,"phoneExt":11,"email":11},"Nizar Chahin",{"facility":203,"status":54,"city":204,"state":205,"zip":206,"country":44,"countryCode":45,"cosmosGeoPoint":207,"geoPoint":211,"contacts":212},"Semmes Murphey Clinic","Memphis","Tennessee","38120",{"type":47,"coordinates":208},[209,210],-90.04898,35.14953,{"lat":210,"lon":209},[213,217],{"name":214,"role":35,"phone":215,"phoneExt":11,"email":216},"Courtney Berryman","901-260-6111","cberryman@semmes-murphey.com",{"name":218,"role":69,"phone":11,"phoneExt":11,"email":11},"Tulio Bertorini",{"facility":220,"status":40,"city":221,"state":11,"zip":11,"country":222,"countryCode":223,"cosmosGeoPoint":224,"geoPoint":228,"contacts":11},"UZ Leuven","Leuven","Belgium","BE",{"type":47,"coordinates":225},[226,227],4.70093,50.87959,{"lat":227,"lon":226},{"facility":230,"status":54,"city":231,"state":11,"zip":11,"country":232,"countryCode":233,"cosmosGeoPoint":234,"geoPoint":238,"contacts":239},"Aarhus University Hospital","Aarhus","Denmark","DK",{"type":47,"coordinates":235},[236,237],10.21076,56.15674,{"lat":237,"lon":236},[240,244],{"name":241,"role":35,"phone":242,"phoneExt":11,"email":243},"Josefine Nielsen","+45 23 88 25 83","josenl@rm.dk",{"name":245,"role":69,"phone":11,"phoneExt":11,"email":11},"Henning Andersen",{"facility":247,"status":54,"city":248,"state":11,"zip":11,"country":232,"countryCode":233,"cosmosGeoPoint":249,"geoPoint":253,"contacts":254},"Rigshospitalet University of Copenhagen","Copenhagen",{"type":47,"coordinates":250},[251,252],12.56553,55.67594,{"lat":252,"lon":251},[255,259],{"name":256,"role":35,"phone":257,"phoneExt":11,"email":258},"Nicolai Preisler","+45 3545 9473","nicolai.rasmus.preisler@regionh.dk",{"name":256,"role":69,"phone":11,"phoneExt":11,"email":11},{"facility":261,"status":54,"city":262,"state":11,"zip":11,"country":263,"countryCode":264,"cosmosGeoPoint":265,"geoPoint":269,"contacts":270},"Centre de référence des maladies neuromusculaires AOC-CHU de Bordeaux - Hôpital Pellegrin","Bordeaux","France","FR",{"type":47,"coordinates":266},[267,268],-0.58046,44.84124,{"lat":268,"lon":267},[271,275],{"name":272,"role":35,"phone":273,"phoneExt":11,"email":274},"Zahra Hamzi","+33 7 67 02 63 35","zahra.hamzi@chu-bordeaux.fr",{"name":276,"role":69,"phone":11,"phoneExt":11,"email":11},"Guilhem Sole",{"facility":278,"status":54,"city":279,"state":11,"zip":11,"country":263,"countryCode":264,"cosmosGeoPoint":280,"geoPoint":284,"contacts":285},"Centre de Référence des Maladies Neuromusculaires et de la SLA","Marseille",{"type":47,"coordinates":281},[282,283],5.38107,43.29695,{"lat":283,"lon":282},[286,290],{"name":287,"role":35,"phone":288,"phoneExt":11,"email":289},"Shahram Attarian","+33 0491386579","Shahram.ATTARIAN@ap-hm.fr",{"name":287,"role":69,"phone":11,"phoneExt":11,"email":11},{"facility":292,"status":54,"city":293,"state":11,"zip":11,"country":263,"countryCode":264,"cosmosGeoPoint":294,"geoPoint":298,"contacts":299},"Centre Hospitalier Universitaire de Nantes - Hôtel Dieu Centre de Référence des Maladies Neuromusculaires Rares -","Nantes",{"type":47,"coordinates":295},[296,297],-1.55336,47.21725,{"lat":297,"lon":296},[300,304],{"name":301,"role":35,"phone":302,"phoneExt":11,"email":303},"Yann Pereon","+33 2 40 08 37 04","Yann.Pereon@univ-nantes.fr",{"name":301,"role":69,"phone":11,"phoneExt":11,"email":11},{"facility":306,"status":54,"city":307,"state":11,"zip":11,"country":263,"countryCode":264,"cosmosGeoPoint":308,"geoPoint":312,"contacts":313},"CHU de Nice","Nice",{"type":47,"coordinates":309},[310,311],7.26608,43.70313,{"lat":311,"lon":310},[314],{"name":315,"role":35,"phone":316,"phoneExt":11,"email":317},"Prof. Sabrina Sacconi","+33492037267","sacconi.s@chu-nice.fr",{"facility":319,"status":54,"city":307,"state":11,"zip":11,"country":263,"countryCode":264,"cosmosGeoPoint":320,"geoPoint":322,"contacts":323},"Unité de Recherche Clinique NeuroSciences",{"type":47,"coordinates":321},[310,311],{"lat":311,"lon":310},[324,328],{"name":325,"role":35,"phone":326,"phoneExt":11,"email":327},"Saskia Bresch","+33 04 92 03 89 05","bord.m@chu-nice.fr",{"name":325,"role":69,"phone":11,"phoneExt":11,"email":11},{"facility":330,"status":331,"city":332,"state":11,"zip":11,"country":122,"countryCode":333,"cosmosGeoPoint":334,"geoPoint":338,"contacts":11},"JSC Curatio","ACTIVE_NOT_RECRUITING","Tbilisi","GE",{"type":47,"coordinates":335},[336,337],44.83412,41.69143,{"lat":337,"lon":336},{"facility":340,"status":331,"city":332,"state":11,"zip":11,"country":122,"countryCode":333,"cosmosGeoPoint":341,"geoPoint":343,"contacts":11},"LTD David Tatishvili Health Center",{"type":47,"coordinates":342},[336,337],{"lat":337,"lon":336},{"facility":345,"status":331,"city":332,"state":11,"zip":11,"country":122,"countryCode":333,"cosmosGeoPoint":346,"geoPoint":348,"contacts":11},"Ltd New Hospitals",{"type":47,"coordinates":347},[336,337],{"lat":337,"lon":336},{"facility":350,"status":54,"city":351,"state":11,"zip":352,"country":353,"countryCode":354,"cosmosGeoPoint":355,"geoPoint":359,"contacts":360},"ASST Papa Giovanni XXIII (Azienda Ospedaliera Papa Giovanni XXIII)","Bergamo","21127","Italy","IT",{"type":47,"coordinates":356},[357,358],9.66721,45.69601,{"lat":358,"lon":357},[361,365],{"name":362,"role":35,"phone":363,"phoneExt":11,"email":364},"Manlio Sgarzi","+393356462101","msgarzi@asst-pg23.it",{"name":362,"role":69,"phone":11,"phoneExt":11,"email":11},{"facility":367,"status":54,"city":368,"state":11,"zip":369,"country":353,"countryCode":354,"cosmosGeoPoint":370,"geoPoint":374,"contacts":375},"IRCCS Istituo delle Scienze neurologiche di Bologna, UOC Clinica neurologica Ospedale","Bologna","40139",{"type":47,"coordinates":371},[372,373],11.33875,44.49381,{"lat":373,"lon":372},[376,380],{"name":377,"role":35,"phone":378,"phoneExt":11,"email":379},"Prof. Rocco Liguori","+390514966917","Rocco.liguori@unibo.it",{"name":377,"role":69,"phone":11,"phoneExt":11,"email":11},{"facility":382,"status":54,"city":383,"state":11,"zip":384,"country":353,"countryCode":354,"cosmosGeoPoint":385,"geoPoint":389,"contacts":390},"IRCCS Ospedale Policlinico San Martino","Genova","16132",{"type":47,"coordinates":386},[387,388],11.87211,45.21604,{"lat":388,"lon":387},[391,395],{"name":392,"role":35,"phone":393,"phoneExt":11,"email":394},"Dr. Marina Grandis","+390103537562","mgrandis@neurologia.unige.it",{"name":392,"role":69,"phone":11,"phoneExt":11,"email":11},{"facility":397,"status":54,"city":398,"state":11,"zip":399,"country":353,"countryCode":354,"cosmosGeoPoint":400,"geoPoint":404,"contacts":405},"IRCCS Fondazione Istituto Neurologico Carlo Besta, Dipartimento di Ricerca e Sviluppo clinico","Milan","20133",{"type":47,"coordinates":401},[402,403],12.59836,42.78235,{"lat":403,"lon":402},[406,410],{"name":407,"role":35,"phone":408,"phoneExt":11,"email":409},"Carlo Antozzi","+ 39 3356157625","carlo.antozzi@istituto-besta.it",{"name":407,"role":69,"phone":11,"phoneExt":11,"email":11},{"facility":412,"status":54,"city":398,"state":11,"zip":11,"country":353,"countryCode":354,"cosmosGeoPoint":413,"geoPoint":415,"contacts":416},"DIMER, IRCCS, Ospedale San Raffaele",{"type":47,"coordinates":414},[402,403],{"lat":403,"lon":402},[417,421],{"name":418,"role":35,"phone":11,"phoneExt":419,"email":420},"Dr.ssa Claudia Panciroli","390226439376","PANCIROLI.CLAUDIA@hsr.it",{"name":422,"role":69,"phone":11,"phoneExt":11,"email":11},"Dr. Fazio Raffaella",{"facility":424,"status":54,"city":425,"state":11,"zip":426,"country":353,"countryCode":354,"cosmosGeoPoint":427,"geoPoint":431,"contacts":432},"Centro Sclerosi Multipla Napoli - AOU Vanvitelli","Naples","80138",{"type":47,"coordinates":428},[429,430],14.26811,40.85216,{"lat":430,"lon":429},[433,437],{"name":434,"role":35,"phone":435,"phoneExt":11,"email":436},"Alvino Bisecco","+39 0815665252","alvino.bisecco@unicampania.it",{"name":434,"role":69,"phone":11,"phoneExt":11,"email":11},{"facility":439,"status":54,"city":440,"state":11,"zip":441,"country":353,"countryCode":354,"cosmosGeoPoint":442,"geoPoint":446,"contacts":447},"AOU Pisana","Pisa","56126",{"type":47,"coordinates":443},[444,445],10.4036,43.70853,{"lat":445,"lon":444},[448,452],{"name":449,"role":35,"phone":450,"phoneExt":11,"email":451},"Maestr Tassoni","+ 39050995519","m.maestri@ao-pisa.toscana.it",{"name":453,"role":69,"phone":11,"phoneExt":11,"email":11},"Michelangelo Maestri Tassoni",{"facility":455,"status":54,"city":456,"state":11,"zip":457,"country":353,"countryCode":354,"cosmosGeoPoint":458,"geoPoint":462,"contacts":463},"Azienda Ospedaliera Sant'Andrea - Universita di Roma La Sapienza","Roma","00189",{"type":47,"coordinates":459},[460,461],11.10642,44.99364,{"lat":461,"lon":460},[464,468],{"name":465,"role":35,"phone":466,"phoneExt":11,"email":467},"Matteo Garibaldi","+390633775937","Matteo.garibaldi@uniroma1.it",{"name":465,"role":69,"phone":11,"phoneExt":11,"email":11},{"facility":470,"status":54,"city":471,"state":11,"zip":472,"country":473,"countryCode":474,"cosmosGeoPoint":475,"geoPoint":479,"contacts":480},"Leiden Universitair Medisch Centrum (LUMC)","Leiden","2333","Netherlands","NL",{"type":47,"coordinates":476},[477,478],4.49306,52.15833,{"lat":478,"lon":477},[481,484],{"name":482,"role":35,"phone":11,"phoneExt":11,"email":483},"Jan Verschuuren","Myasthenie@Lumc.nl",{"name":482,"role":69,"phone":11,"phoneExt":11,"email":11},{"facility":486,"status":54,"city":487,"state":11,"zip":11,"country":488,"countryCode":489,"cosmosGeoPoint":490,"geoPoint":494,"contacts":495},"Neurologia Śląska Centrum Medyczne","Katowice","Poland","PL",{"type":47,"coordinates":491},[492,493],19.02173,50.2597,{"lat":493,"lon":492},[496,500],{"name":497,"role":35,"phone":498,"phoneExt":11,"email":499},"Marek Smilowski","+48500282494","Marek.smilowski2@gmail.com",{"name":501,"role":69,"phone":11,"phoneExt":11,"email":11},"Dr. Marek Smilowski",{"facility":503,"status":54,"city":504,"state":11,"zip":11,"country":488,"countryCode":489,"cosmosGeoPoint":505,"geoPoint":509,"contacts":510},"Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie sp.z o.o","Krakow",{"type":47,"coordinates":506},[507,508],19.93658,50.06143,{"lat":508,"lon":507},[511,515],{"name":512,"role":35,"phone":513,"phoneExt":11,"email":514},"Jan Kubicki","+48 12 6468 778","badaniakliniczne@rydygierkrakow.pl",{"name":516,"role":69,"phone":11,"phoneExt":11,"email":11},"Ryszard Nowak",{"facility":518,"status":54,"city":519,"state":11,"zip":520,"country":488,"countryCode":489,"cosmosGeoPoint":521,"geoPoint":525,"contacts":526},"Centrum Medyczne Hope Clinic","Lublin","20701",{"type":47,"coordinates":522},[523,524],22.57009,51.25058,{"lat":524,"lon":523},[527,531],{"name":528,"role":35,"phone":529,"phoneExt":11,"email":530},"Dr. Sebastian Szklener","48 666165103","sebastianszklener@gmail.com",{"name":528,"role":69,"phone":11,"phoneExt":11,"email":11},{"facility":533,"status":54,"city":519,"state":11,"zip":11,"country":488,"countryCode":489,"cosmosGeoPoint":534,"geoPoint":536,"contacts":537},"Galen Clinic",{"type":47,"coordinates":535},[523,524],{"lat":524,"lon":523},[538,542],{"name":539,"role":35,"phone":540,"phoneExt":11,"email":541},"Urszula Chyrchel-Paszkiewicz","+ 48602102105","pgluchyrchel@gmail.com",{"name":543,"role":69,"phone":11,"phoneExt":11,"email":11},"Dr. Chyrchel-Paszkiewicz Urszula",{"facility":545,"status":54,"city":546,"state":11,"zip":11,"country":488,"countryCode":489,"cosmosGeoPoint":547,"geoPoint":551,"contacts":552},"NeuroCor Banaszkiewicz, Tomaszewski Lekarze Spółka Partnerska","Myślenice",{"type":47,"coordinates":548},[549,550],19.9383,49.83383,{"lat":550,"lon":549},[553],{"name":554,"role":35,"phone":555,"phoneExt":11,"email":556},"Krzysztof Banaszkiewicz","+48691776505","badania@neurocor.pl",{"facility":558,"status":54,"city":559,"state":11,"zip":11,"country":488,"countryCode":489,"cosmosGeoPoint":560,"geoPoint":564,"contacts":565},"Centrum Medyczne Neuro Protect","Warsaw",{"type":47,"coordinates":561},[562,563],21.01178,52.22977,{"lat":563,"lon":562},[566,570],{"name":567,"role":35,"phone":568,"phoneExt":11,"email":569},"Grudniak Mariusz","+48 22 699 60 15","mariusz.grudniak@neuroprotect.pl",{"name":571,"role":69,"phone":11,"phoneExt":11,"email":11},"Dr. Grudniak Mariusz",{"facility":573,"status":40,"city":574,"state":11,"zip":11,"country":575,"countryCode":576,"cosmosGeoPoint":577,"geoPoint":581,"contacts":11},"University Clinical Center of Serbia, Neurology Clinic","Belgrade","Serbia","RS",{"type":47,"coordinates":578},[579,580],20.46513,44.80401,{"lat":580,"lon":579},{"facility":583,"status":54,"city":584,"state":11,"zip":11,"country":575,"countryCode":576,"cosmosGeoPoint":585,"geoPoint":589,"contacts":590},"University Clinical Center Nis, Neurology Clinic","Niš",{"type":47,"coordinates":586},[587,588],21.90333,43.32472,{"lat":588,"lon":587},[591,595],{"name":592,"role":35,"phone":593,"phoneExt":11,"email":594},"Gordana Djordjevic","+381631094549","gordanadjor@gmail.com",{"name":592,"role":69,"phone":11,"phoneExt":11,"email":11},{"facility":597,"status":54,"city":598,"state":11,"zip":11,"country":599,"countryCode":600,"cosmosGeoPoint":601,"geoPoint":605,"contacts":606},"Hospìtal Universitari Vall d'Hebrón","Barcelona","Spain","ES",{"type":47,"coordinates":602},[603,604],2.15899,41.38879,{"lat":604,"lon":603},[607,610],{"name":608,"role":35,"phone":11,"phoneExt":11,"email":609},"Consuelo Garcia","consuelo.garcia@vhir.org",{"name":611,"role":69,"phone":11,"phoneExt":11,"email":11},"Raul Juntas Morales",{"type":613,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100547974","phase-2-safety-and-efficacy-of-3-dose-levels-of-nmd670-in-adult-patients-with-myasthenia-gravis-100547974",false,"NCT06414954","Safety and Efficacy of 3 Dose Levels of NMD670 in Adult Patients With Myasthenia Gravis","A Phase 2b, Randomised, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of 3 Dose Levels of NMD670 Over 21 Days in Adult Patients With AChR\u002FMuSK-Ab+ Myasthenia Gravis","SYNAPSE-MG","Inclusion Criteria:\n\n* Participant must be a male or female being 18 or more, at the time of signing the informed consent\n* Diagnosis of MG, MGFA class II, III or IV\n* Documented positive AChR or MuSK antibody test.\n* Participant must be able to swallow tablets\n* Body mass index between 18 and 35 kg\u002Fm2, inclusive, at screening, and with a minimum weight of 40 kg\n* Contraceptive use by men and women must be consistent with local regulations regarding the methods of contraception for those participating in clinical studies\n* Participant is capable of and has given signed informed consent\n\nExclusion Criteria:\n\n* Known medical or psychological condition(s) or risk factor that, in the opinion of the Investigator, might interfere with the patient's full participation in the study, pose any additional risk for the patient, or confound the assessment of the patient or outcome of the study\n* Participants with other significant clinical and\u002For laboratory safety findings that may interfere with the conduction or interpretation of the study\n* Participants that received treatment with an investigational medical product within 30 days or 5 half-lives of the medication, whichever is longer prior to Day 1\n* Participants with history of poor compliance with relevant MG therapy\n* Female patients who plan to become pregnant during the study or are currently pregnant or breastfeeding","ALL","18 Years",{"count":625,"type":626},84,"ESTIMATED","INTERVENTIONAL",[629],"PHASE2","This Phase 2 proof-of-concept, dose range finding study aims to evaluate the safety and efficacy of 3 dose levels of NMD670 vs placebo in adult patients with MG with antibodies against AChR or MuSK, administered twice a day (BID) for 21 days.",[632,633],"Myasthenia Gravis","Myasthenia Gravis, MuSK","2026-06-29",{"date":636,"type":637},"2026-07-01","ACTUAL",{"date":639,"type":637},"2024-05-16",{"date":641,"type":626},"2026-12",{"name":5,"class":6},40]