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TRANSCEND)","Inclusion Criteria:\n\n* Newly diagnosed or relapsing ANCA-associated vasculitis, GPA and MPA subtypes consistent with the 2022 ACR\u002FEULAR classification criteria for GPA and MPA for whom treatment with rituximab or cyclophosphamide is considered.\n* Positive test for antibodies to either PR3-ANCA or MPO-ANCA at Screening or in the past by a quantitative assay (for example, ELISA, bead assay).\n* At least one major item, or at least 3 minor items, or at least 2 renal items in the BVAS.\n\nExclusion Criteria:\n\n* Other systemic diseases that, in the judgment of the Investigator, constitute the primary illness, including but not limited to: eosinophilic granulomatosis with polyangiitis (EGPA), systemic lupus erythematosus, IgA nephropathy and\u002For IgA associated vasculitis with or without Henoch-Schonlein purpura, rheumatoid vasculitis, Sjogren's syndrome, anti-GBM disease, cryoglobulinemic vasculitis, autoimmune hemolytic anemia, or mixed connective tissue disease.\n* Alveolar hemorrhage requiring invasive pulmonary ventilation support at Screening.\n* Any diseases or conditions that, in the judgment of the Investigator, present a substantial clinical risk to participate in this study.\n* For patients with a previous diagnosis of CKD, patients known to have a stable eGFR for greater than 3 months prior to Screening and a decline less than 25% of previous eGFR at Screening will be excluded.","ALL","18 Years","80 Years",{"count":667,"type":668},75,"ESTIMATED","INTERVENTIONAL",[671],"PHASE2","The primary objective of this study is to evaluate the safety and tolerability of tarperprumig in participants with newly diagnosed or relapsing anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis.",[674],"Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis",[676,674,677,678],"ANCA-associated vasculitis","Vasculitis","IMP (Tarperprumig)","2026-06-15",{"date":681,"type":682},"2026-06-16","ACTUAL",{"date":684,"type":682},"2025-11-26",{"date":686,"type":668},"2028-02-14",{"name":5,"class":6},78]