[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100512340":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":29,"responsibleParty":763,"collaborators":19,"id":765,"slug":766,"hasResults":767,"nctId":768,"briefTitle":769,"officialTitle":770,"acronym":771,"eligibilityCriteria":772,"healthyVolunteers":767,"sex":773,"minAge":774,"maxAge":19,"enrollmentInfo":775,"targetDuration":19,"studyType":778,"phases":779,"briefSummary":781,"conditions":782,"keywords":784,"overallStatus":32,"whyStopped":19,"lastUpdateSubmitDate":790,"lastUpdatePostDateStruct":791,"startDateStruct":794,"completionDateStruct":796,"leadSponsor":798,"locationsCount":799},{"fullName":5,"class":6},"Protara Therapeutics","INDUSTRY",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"TARA-002","EXPERIMENTAL","TARA-002 is a lyophilized biological preparation for instillation containing cells of Streptococcus pyogenes (Group A, type 3) Su strain.",[13],"Biological: TARA-002",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"BIOLOGICAL","All participants will receive 6 weekly instillations of TARA-002 at the established RP2D (First Treatment Period). Participants who are eligible for reinduction after the First Treatment Period will receive 6 additional weekly doses of TARA-002 instillation as part of the Second Treatment Period. Participants confirmed to have a complete response after the First Treatment Period will receive 3 additional weekly doses of TARA-002 instillation as maintenance during the Second Treatment Period. All eligible participants will receive 3 weekly doses of TARA-002 instillation as part of the Third Treatment Period (maintenance) at Months 6, 9, 12, 15, 18 and 24. Following the Third Treatment Period, all participants will continue to the Follow up Period from Month 27 until Month 60.",[9],null,[21],{"name":22,"affiliation":5,"role":23},"Chief Scientific Operations Officer","STUDY_DIRECTOR",[25],{"name":22,"role":26,"phone":27,"phoneExt":19,"email":28},"CONTACT","16468440337","clinicaltrials@protaratx.com",[30,47,59,70,82,94,104,115,125,136,148,159,170,181,191,201,213,225,234,246,258,268,280,288,298,308,318,329,339,351,363,375,386,396,407,418,429,437,443,454,466,478,491,499,505,509,520,528,539,553,560,572,580,588,600,611,622,634,644,653,659,668,679,686,696,703,710,721,732,739,750],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Urology Centers of Alabama","RECRUITING","Homewood","Alabama","35209","United States","US",{"type":39,"coordinates":40},"Point",[41,42],-86.80082,33.47177,{"lat":42,"lon":41},[45],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},"Use Central Contact",{"facility":48,"status":32,"city":49,"state":50,"zip":51,"country":36,"countryCode":37,"cosmosGeoPoint":52,"geoPoint":56,"contacts":57},"Mayo Clinic","Phoenix","Arizona","85054",{"type":39,"coordinates":53},[54,55],-112.07404,33.44838,{"lat":55,"lon":54},[58],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":60,"status":32,"city":61,"state":50,"zip":62,"country":36,"countryCode":37,"cosmosGeoPoint":63,"geoPoint":67,"contacts":68},"East Valley Urology Center of Arizona","Queen Creek","85140",{"type":39,"coordinates":64},[65,66],-111.6343,33.24866,{"lat":66,"lon":65},[69],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":71,"status":32,"city":72,"state":73,"zip":74,"country":36,"countryCode":37,"cosmosGeoPoint":75,"geoPoint":79,"contacts":80},"Arkansas Urology","Little Rock","Arkansas","72211",{"type":39,"coordinates":76},[77,78],-92.28959,34.74648,{"lat":78,"lon":77},[81],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":83,"status":32,"city":84,"state":85,"zip":86,"country":36,"countryCode":37,"cosmosGeoPoint":87,"geoPoint":91,"contacts":92},"Michael Oefelein Clinical Trials","Bakersfield","California","93301",{"type":39,"coordinates":88},[89,90],-119.01871,35.37329,{"lat":90,"lon":89},[93],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":95,"status":96,"city":97,"state":85,"zip":98,"country":36,"countryCode":37,"cosmosGeoPoint":99,"geoPoint":103,"contacts":19},"Urology Group of Southern California","TERMINATED","Los Angeles","90017",{"type":39,"coordinates":100},[101,102],-118.24368,34.05223,{"lat":102,"lon":101},{"facility":105,"status":32,"city":106,"state":85,"zip":107,"country":36,"countryCode":37,"cosmosGeoPoint":108,"geoPoint":112,"contacts":113},"University of California Irvine Medical Center","Orange","92697",{"type":39,"coordinates":109},[110,111],-117.85311,33.78779,{"lat":111,"lon":110},[114],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":116,"status":117,"city":118,"state":85,"zip":119,"country":36,"countryCode":37,"cosmosGeoPoint":120,"geoPoint":124,"contacts":19},"Genesis Research","WITHDRAWN","San Diego","92123",{"type":39,"coordinates":121},[122,123],-117.16472,32.71571,{"lat":123,"lon":122},{"facility":126,"status":32,"city":127,"state":85,"zip":128,"country":36,"countryCode":37,"cosmosGeoPoint":129,"geoPoint":133,"contacts":134},"Genesis Research LLC","Torrance","90505",{"type":39,"coordinates":130},[131,132],-118.34063,33.83585,{"lat":132,"lon":131},[135],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":137,"status":32,"city":138,"state":139,"zip":140,"country":36,"countryCode":37,"cosmosGeoPoint":141,"geoPoint":145,"contacts":146},"Colorado University - Anshutz","Aurora","Colorado","80045",{"type":39,"coordinates":142},[143,144],-104.83192,39.72943,{"lat":144,"lon":143},[147],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":149,"status":32,"city":150,"state":139,"zip":151,"country":36,"countryCode":37,"cosmosGeoPoint":152,"geoPoint":156,"contacts":157},"AdventHealth Medical Group Urology of Denver","Denver","80211",{"type":39,"coordinates":153},[154,155],-104.9847,39.73915,{"lat":155,"lon":154},[158],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":160,"status":32,"city":161,"state":139,"zip":162,"country":36,"countryCode":37,"cosmosGeoPoint":163,"geoPoint":167,"contacts":168},"Advanced Urology","Lakewood","80228",{"type":39,"coordinates":164},[165,166],-105.08137,39.70471,{"lat":166,"lon":165},[169],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":171,"status":32,"city":172,"state":139,"zip":173,"country":36,"countryCode":37,"cosmosGeoPoint":174,"geoPoint":178,"contacts":179},"Urology Associates of Denver","Lone Tree","80124",{"type":39,"coordinates":175},[176,177],-104.8863,39.55171,{"lat":177,"lon":176},[180],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":182,"status":117,"city":183,"state":184,"zip":185,"country":36,"countryCode":37,"cosmosGeoPoint":186,"geoPoint":190,"contacts":19},"University of Florida Health Jacksonville","Gainesville","Florida","32611",{"type":39,"coordinates":187},[188,189],-82.32483,29.65163,{"lat":189,"lon":188},{"facility":48,"status":32,"city":192,"state":184,"zip":193,"country":36,"countryCode":37,"cosmosGeoPoint":194,"geoPoint":198,"contacts":199},"Jacksonville","32224",{"type":39,"coordinates":195},[196,197],-81.65565,30.33218,{"lat":197,"lon":196},[200],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":202,"status":32,"city":203,"state":204,"zip":205,"country":36,"countryCode":37,"cosmosGeoPoint":206,"geoPoint":210,"contacts":211},"Comprehensive Urologic Care","Lake Barrington","Illinois","60010",{"type":39,"coordinates":207},[208,209],-88.15258,42.21252,{"lat":209,"lon":208},[212],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":214,"status":32,"city":215,"state":216,"zip":217,"country":36,"countryCode":37,"cosmosGeoPoint":218,"geoPoint":222,"contacts":223},"Southern Urology","Lafayette","Louisiana","70508",{"type":39,"coordinates":219},[220,221],-92.01984,30.22409,{"lat":221,"lon":220},[224],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":226,"status":117,"city":227,"state":216,"zip":228,"country":36,"countryCode":37,"cosmosGeoPoint":229,"geoPoint":233,"contacts":19},"Ochsner Health LSU - Regional Urology","Shreveport","71105",{"type":39,"coordinates":230},[231,232],-93.75018,32.52515,{"lat":232,"lon":231},{"facility":235,"status":32,"city":236,"state":237,"zip":238,"country":36,"countryCode":37,"cosmosGeoPoint":239,"geoPoint":243,"contacts":244},"Brigham and Women's Hospital","Boston","Massachusetts","02115",{"type":39,"coordinates":240},[241,242],-71.05977,42.35843,{"lat":242,"lon":241},[245],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":247,"status":32,"city":248,"state":249,"zip":250,"country":36,"countryCode":37,"cosmosGeoPoint":251,"geoPoint":255,"contacts":256},"Minnesota Urology, Woodbury","Bloomington","Minnesota","55425",{"type":39,"coordinates":252},[253,254],-93.29828,44.8408,{"lat":254,"lon":253},[257],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":48,"status":32,"city":259,"state":249,"zip":260,"country":36,"countryCode":37,"cosmosGeoPoint":261,"geoPoint":265,"contacts":266},"Rochester","55905",{"type":39,"coordinates":262},[263,264],-92.4699,44.02163,{"lat":264,"lon":263},[267],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":269,"status":32,"city":270,"state":271,"zip":272,"country":36,"countryCode":37,"cosmosGeoPoint":273,"geoPoint":277,"contacts":278},"Renown Regional Medical Center","St Louis","Missouri","63110",{"type":39,"coordinates":274},[275,276],-90.19789,38.62727,{"lat":276,"lon":275},[279],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":281,"status":32,"city":270,"state":271,"zip":282,"country":36,"countryCode":37,"cosmosGeoPoint":283,"geoPoint":285,"contacts":286},"Specialty Clinic Research of St. Louis","63141",{"type":39,"coordinates":284},[275,276],{"lat":276,"lon":275},[287],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":289,"status":96,"city":290,"state":291,"zip":292,"country":36,"countryCode":37,"cosmosGeoPoint":293,"geoPoint":297,"contacts":19},"AccuMed Research Associates","Garden City","New York","11530",{"type":39,"coordinates":294},[295,296],-73.6343,40.72677,{"lat":296,"lon":295},{"facility":299,"status":32,"city":291,"state":291,"zip":300,"country":36,"countryCode":37,"cosmosGeoPoint":301,"geoPoint":305,"contacts":306},"Laura & Isaac Perlmutter Cancer Center - NYU Langone Health","10016",{"type":39,"coordinates":302},[303,304],-74.00597,40.71427,{"lat":304,"lon":303},[307],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":309,"status":32,"city":259,"state":291,"zip":310,"country":36,"countryCode":37,"cosmosGeoPoint":311,"geoPoint":315,"contacts":316},"University of Rochester, Department of Urology","14642",{"type":39,"coordinates":312},[313,314],-77.61556,43.15478,{"lat":314,"lon":313},[317],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":319,"status":32,"city":320,"state":291,"zip":321,"country":36,"countryCode":37,"cosmosGeoPoint":322,"geoPoint":326,"contacts":327},"Montefiore Medical Center","The Bronx","10467",{"type":39,"coordinates":323},[324,325],-73.86641,40.84985,{"lat":325,"lon":324},[328],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":330,"status":117,"city":331,"state":332,"zip":333,"country":36,"countryCode":37,"cosmosGeoPoint":334,"geoPoint":338,"contacts":19},"University of Toledo","Toledo","Ohio","43606",{"type":39,"coordinates":335},[336,337],-83.55521,41.66394,{"lat":337,"lon":336},{"facility":340,"status":32,"city":341,"state":342,"zip":343,"country":36,"countryCode":37,"cosmosGeoPoint":344,"geoPoint":348,"contacts":349},"University of Pittsburgh Medical Center","Pittsburgh","Pennsylvania","15213",{"type":39,"coordinates":345},[346,347],-79.99589,40.44062,{"lat":347,"lon":346},[350],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":352,"status":32,"city":353,"state":354,"zip":355,"country":36,"countryCode":37,"cosmosGeoPoint":356,"geoPoint":360,"contacts":361},"Carolina Urologic Research Center","Myrtle Beach","South Carolina","29572",{"type":39,"coordinates":357},[358,359],-78.88669,33.68906,{"lat":359,"lon":358},[362],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":364,"status":32,"city":365,"state":366,"zip":367,"country":36,"countryCode":37,"cosmosGeoPoint":368,"geoPoint":372,"contacts":373},"Conrad Person Clinic","Memphis","Tennessee","38128",{"type":39,"coordinates":369},[370,371],-90.04898,35.14953,{"lat":371,"lon":370},[374],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":376,"status":32,"city":377,"state":366,"zip":378,"country":36,"countryCode":37,"cosmosGeoPoint":379,"geoPoint":383,"contacts":384},"Urology Associates PC","Nashville","37209",{"type":39,"coordinates":380},[381,382],-86.78444,36.16589,{"lat":382,"lon":381},[385],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":387,"status":117,"city":388,"state":389,"zip":390,"country":36,"countryCode":37,"cosmosGeoPoint":391,"geoPoint":395,"contacts":19},"Amarillo Urology Research","Amarillo","Texas","79106",{"type":39,"coordinates":392},[393,394],-101.8313,35.222,{"lat":394,"lon":393},{"facility":397,"status":32,"city":398,"state":389,"zip":399,"country":36,"countryCode":37,"cosmosGeoPoint":400,"geoPoint":404,"contacts":405},"Urology Partners of North Texas","Arlington","76017",{"type":39,"coordinates":401},[402,403],-97.10807,32.73569,{"lat":403,"lon":402},[406],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":408,"status":32,"city":409,"state":389,"zip":410,"country":36,"countryCode":37,"cosmosGeoPoint":411,"geoPoint":415,"contacts":416},"Urology Austin, LLC","Austin","78745",{"type":39,"coordinates":412},[413,414],-97.74306,30.26715,{"lat":414,"lon":413},[417],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":419,"status":32,"city":420,"state":389,"zip":421,"country":36,"countryCode":37,"cosmosGeoPoint":422,"geoPoint":426,"contacts":427},"Houston Metro Urology","Houston","77027",{"type":39,"coordinates":423},[424,425],-95.36327,29.76328,{"lat":425,"lon":424},[428],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":430,"status":32,"city":420,"state":389,"zip":431,"country":36,"countryCode":37,"cosmosGeoPoint":432,"geoPoint":434,"contacts":435},"Houston Methodist Hospital","77030",{"type":39,"coordinates":433},[424,425],{"lat":425,"lon":424},[436],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":438,"status":117,"city":420,"state":389,"zip":439,"country":36,"countryCode":37,"cosmosGeoPoint":440,"geoPoint":442,"contacts":19},"Clinical Trial Network","77074",{"type":39,"coordinates":441},[424,425],{"lat":425,"lon":424},{"facility":444,"status":32,"city":445,"state":389,"zip":446,"country":36,"countryCode":37,"cosmosGeoPoint":447,"geoPoint":451,"contacts":452},"UT Health San Antonio","San Antonio","78229",{"type":39,"coordinates":448},[449,450],-98.49363,29.42412,{"lat":450,"lon":449},[453],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":455,"status":32,"city":456,"state":457,"zip":458,"country":36,"countryCode":37,"cosmosGeoPoint":459,"geoPoint":463,"contacts":464},"Virginia Urology","Richmond","Virginia","23235",{"type":39,"coordinates":460},[461,462],-77.46026,37.55376,{"lat":462,"lon":461},[465],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":467,"status":32,"city":468,"state":469,"zip":470,"country":36,"countryCode":37,"cosmosGeoPoint":471,"geoPoint":475,"contacts":476},"Spokane Urology","Spokane","Washington","99202",{"type":39,"coordinates":472},[473,474],-117.42908,47.65966,{"lat":474,"lon":473},[477],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":479,"status":32,"city":480,"state":19,"zip":481,"country":482,"countryCode":483,"cosmosGeoPoint":484,"geoPoint":488,"contacts":489},"Hospital Italiano de Buenos Aires (HIBA)","Buenos Aires","C1199ABB","Argentina","AR",{"type":39,"coordinates":485},[486,487],-58.37723,-34.61315,{"lat":487,"lon":486},[490],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":492,"status":32,"city":480,"state":19,"zip":493,"country":482,"countryCode":483,"cosmosGeoPoint":494,"geoPoint":496,"contacts":497},"Hospital Britanico de Buenos Aires","C1280",{"type":39,"coordinates":495},[486,487],{"lat":487,"lon":486},[498],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":500,"status":32,"city":501,"state":19,"zip":502,"country":482,"countryCode":483,"cosmosGeoPoint":19,"geoPoint":19,"contacts":503},"Centro Argentino de Urologia","CABA","C1419",[504],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":506,"status":32,"city":501,"state":19,"zip":502,"country":482,"countryCode":483,"cosmosGeoPoint":19,"geoPoint":19,"contacts":507},"Hospital Sirio Libanes",[508],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":510,"status":32,"city":511,"state":19,"zip":512,"country":482,"countryCode":483,"cosmosGeoPoint":513,"geoPoint":517,"contacts":518},"Centro Urologico Profesor Bengio SA","Córdoba","X5000KPH",{"type":39,"coordinates":514},[515,516],-64.18853,-31.40648,{"lat":516,"lon":515},[519],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":521,"status":32,"city":511,"state":19,"zip":522,"country":482,"countryCode":483,"cosmosGeoPoint":523,"geoPoint":525,"contacts":526},"CEMAIC","X5088",{"type":39,"coordinates":524},[515,516],{"lat":516,"lon":515},[527],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":529,"status":32,"city":530,"state":19,"zip":531,"country":482,"countryCode":483,"cosmosGeoPoint":532,"geoPoint":536,"contacts":537},"Clinica Privada Independencia","Munro","1605",{"type":39,"coordinates":533},[534,535],-58.52421,-34.53021,{"lat":535,"lon":534},[538],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":540,"status":32,"city":541,"state":542,"zip":543,"country":544,"countryCode":545,"cosmosGeoPoint":546,"geoPoint":550,"contacts":551},"Kyushu University Hospital","Nova Lima","Minas Gerais","34006-059","Brazil","BR",{"type":39,"coordinates":547},[548,549],-43.84667,-19.98556,{"lat":549,"lon":548},[552],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":554,"status":32,"city":541,"state":542,"zip":543,"country":544,"countryCode":545,"cosmosGeoPoint":555,"geoPoint":557,"contacts":558},"Office of Lucas Nougeria MA",{"type":39,"coordinates":556},[548,549],{"lat":549,"lon":548},[559],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":561,"status":32,"city":562,"state":563,"zip":564,"country":544,"countryCode":545,"cosmosGeoPoint":565,"geoPoint":569,"contacts":570},"Santa Casa de Misericordia de Porto Alegre","Porto Alegre","Rio Grande do Sul","90035-070",{"type":39,"coordinates":566},[567,568],-51.23019,-30.03283,{"lat":568,"lon":567},[571],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":573,"status":32,"city":562,"state":563,"zip":574,"country":544,"countryCode":545,"cosmosGeoPoint":575,"geoPoint":577,"contacts":578},"Nucleo de Pesquisa Clinica do Rio Grande so Sul","90430-001",{"type":39,"coordinates":576},[567,568],{"lat":568,"lon":567},[579],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":581,"status":32,"city":562,"state":563,"zip":582,"country":544,"countryCode":545,"cosmosGeoPoint":583,"geoPoint":585,"contacts":586},"Centro de Urologia Avancada","91350-200",{"type":39,"coordinates":584},[567,568],{"lat":568,"lon":567},[587],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":589,"status":32,"city":590,"state":591,"zip":592,"country":544,"countryCode":545,"cosmosGeoPoint":593,"geoPoint":597,"contacts":598},"Hospital de Clinicas da UNICAMP","Campinas","São Paulo","13083-970",{"type":39,"coordinates":594},[595,596],-47.06083,-22.90556,{"lat":596,"lon":595},[599],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":601,"status":32,"city":602,"state":591,"zip":603,"country":544,"countryCode":545,"cosmosGeoPoint":604,"geoPoint":608,"contacts":609},"Instituto Dor de Pesquisa e Ensino","Jardim Paulista","01401-002",{"type":39,"coordinates":605},[606,607],-46.66439,-23.56675,{"lat":607,"lon":606},[610],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":612,"status":32,"city":613,"state":591,"zip":614,"country":544,"countryCode":545,"cosmosGeoPoint":615,"geoPoint":619,"contacts":620},"Faculdade de Medicina ABC-CEPHO","Santo André","09060-650",{"type":39,"coordinates":616},[617,618],-46.53833,-23.66389,{"lat":618,"lon":617},[621],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":623,"status":96,"city":624,"state":625,"zip":626,"country":627,"countryCode":628,"cosmosGeoPoint":629,"geoPoint":633,"contacts":19},"Exdeo Clinical Research Inc","Abbotsford British Columbia","British Columbia","V2T 1X8","Canada","CA",{"type":39,"coordinates":630},[631,632],-122.25257,49.05798,{"lat":632,"lon":631},{"facility":635,"status":117,"city":636,"state":637,"zip":638,"country":627,"countryCode":628,"cosmosGeoPoint":639,"geoPoint":643,"contacts":19},"Jonathan Giddes Medicine Professional Corporation","Brampton","Ontario","L6T 4S5",{"type":39,"coordinates":640},[641,642],-79.76633,43.68341,{"lat":642,"lon":641},{"facility":645,"status":117,"city":646,"state":637,"zip":647,"country":627,"countryCode":628,"cosmosGeoPoint":648,"geoPoint":652,"contacts":19},"Sunnybrook Research Institute","Toronto","M4N 3M5",{"type":39,"coordinates":649},[650,651],-79.39864,43.70643,{"lat":651,"lon":650},{"facility":654,"status":32,"city":646,"state":637,"zip":655,"country":627,"countryCode":628,"cosmosGeoPoint":656,"geoPoint":658,"contacts":19},"UHN Princess Margaret Cancer Centre Princess Margaret Hospital","M5G 1Z5",{"type":39,"coordinates":657},[650,651],{"lat":651,"lon":650},{"facility":660,"status":32,"city":661,"state":662,"zip":663,"country":664,"countryCode":665,"cosmosGeoPoint":19,"geoPoint":19,"contacts":666},"Komaki City Hospital","Komaki-shi","Aichi-ken","485-0044","Japan","JP",[667],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":669,"status":32,"city":670,"state":662,"zip":671,"country":664,"countryCode":665,"cosmosGeoPoint":672,"geoPoint":676,"contacts":677},"Japanese Red Cross Aichi Medical Center Nayoya Daiichi","Nagoya","435-8511",{"type":39,"coordinates":673},[674,675],136.90641,35.18147,{"lat":675,"lon":674},[678],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":680,"status":32,"city":681,"state":682,"zip":683,"country":664,"countryCode":665,"cosmosGeoPoint":19,"geoPoint":19,"contacts":684},"Fuji City General Hospital","Sakura-shi","Chiba","285-8741",[685],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":540,"status":32,"city":687,"state":687,"zip":688,"country":664,"countryCode":665,"cosmosGeoPoint":689,"geoPoint":693,"contacts":694},"Fukuoka","812-8582",{"type":39,"coordinates":690},[691,692],130.41667,33.6,{"lat":692,"lon":691},[695],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":697,"status":32,"city":698,"state":699,"zip":700,"country":664,"countryCode":665,"cosmosGeoPoint":19,"geoPoint":19,"contacts":701},"Hyogo Prefectural Amagasaki General Medical Center","Amagasaki-shi","Hyōgo","660-8550",[702],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":704,"status":32,"city":705,"state":706,"zip":707,"country":664,"countryCode":665,"cosmosGeoPoint":19,"geoPoint":19,"contacts":708},"Hitachi General Hospital","Hitachi-shi","Ibaraki","317-0077",[709],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":711,"status":32,"city":712,"state":712,"zip":713,"country":664,"countryCode":665,"cosmosGeoPoint":714,"geoPoint":718,"contacts":719},"Niigata Cancer Center Hospital","Niigata","961-8566",{"type":39,"coordinates":715},[716,717],139.04125,37.92259,{"lat":717,"lon":716},[720],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":722,"status":32,"city":723,"state":723,"zip":724,"country":664,"countryCode":665,"cosmosGeoPoint":725,"geoPoint":729,"contacts":730},"Japanese Red Cross Osaka Hospital","Osaka","543-855",{"type":39,"coordinates":726},[727,728],135.50107,34.69379,{"lat":728,"lon":727},[731],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":733,"status":32,"city":734,"state":735,"zip":736,"country":664,"countryCode":665,"cosmosGeoPoint":19,"geoPoint":19,"contacts":737},"Toho University Medical Center Sakura Hospital","Fuji-shi","Shizuoka","417-8567",[738],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":740,"status":32,"city":741,"state":741,"zip":742,"country":664,"countryCode":665,"cosmosGeoPoint":743,"geoPoint":747,"contacts":748},"Toyama University Hospital","Toyama","930-0152",{"type":39,"coordinates":744},[745,746],137.21667,36.7,{"lat":746,"lon":745},[749],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"facility":751,"status":32,"city":752,"state":19,"zip":753,"country":754,"countryCode":755,"cosmosGeoPoint":756,"geoPoint":760,"contacts":761},"Arensia Kapitanivka - PPDS","Kapitanivka","08111","Ukraine","UA",{"type":39,"coordinates":757},[758,759],31.71627,48.92016,{"lat":759,"lon":758},[762],{"name":46,"role":26,"phone":19,"phoneExt":19,"email":19},{"type":764,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR","100512340","phase-2-safety-and-efficacy-study-of-intravesical-instillation-of-tara-002-in-adults-with-high-grade-non-muscle-invasive-bladder-cancer-100512340",false,"NCT05951179","Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer","A Phase 2, Open-Label Study to Evaluate the Safety and Efficacy of Intravesical Instillation of TARA-002 in Adults With High-Grade Non-Muscle Invasive Bladder Cancer","ADVANCED-2","Inclusion Criteria:\n\n* Male or female participants 18 years of age or older at the time of signing informed consent\n* Participants who have voluntarily given written informed consent after the nature of the study has been explained according to applicable requirements prior to study entry\n* Central histologic confirmation of high-grade non-muscle invasive CIS (± Ta\u002FT1) with active disease\n* Participants who are BCG naive, or participants who are BCG exposed and have not received intravesical BCG for at least 24 months prior to the most recent CIS diagnosis (Cohort A). Participants with CIS (± Ta\u002FT1) who are BCG unresponsive.\n\nExclusion Criteria:\n\n* Penicillin allergy (participants with a questionable history of allergy to penicillin will undergo penicillin blood allergy testing via central laboratory\n* Central confirmed variant histology\n* Concomitant prostatic or upper tract urothelial involvement per Investigator's assessment\n* Nodal and metastatic disease are excluded if they existed at any time (whether present or in the past)\n* Any history of ≥ T2 bladder cancer that existed at any point in time in the participant's history\n\nFor more information on eligibility criteria, please contact the Sponsor","ALL","18 Years",{"count":776,"type":777},131,"ESTIMATED","INTERVENTIONAL",[780],"PHASE2","TARA-002-101-Ph2 is an open-label study to investigate the safety and efficacy of intravesical instillation of TARA-002 in adults 18 years of age or older with high-grade CIS NMIBC (± Ta\u002FT1).\n\nThe purpose of this Phase 2 study (TARA-002-101-Ph2) is to further assess the safety and efficacy of TARA-002 at the RP2D which has been established in the Phase 1a dose finding study (TARA-002-101-Ph1a).\n\nThis Phase 2 study includes participants with CIS NMIBC (± Ta\u002FT1) with active disease, defined as disease present at last tumor evaluation (within 3 months) prior to signing the ICF.\n\nParticipants will be enrolled into one of 2 cohorts:\n\nCohort A:\n\n* Participants with CIS (± Ta\u002FT1) who are BCG naive, or\n* Participants with CIS (± Ta\u002FT1) who are BCG exposed and have not received intravesical BCG for at least 24 months prior to the most recent CIS diagnosis\n\nCohort B:\n\n* Participants who are BCG unresponsive",[783],"Non-muscle Invasive Bladder Cancer",[785,786,787,788,789],"Non-muscle invasive bladder Cancer","bladder cancer","high grade Ta","high grade NMIBC","carcinoma in situ","2026-06-25",{"date":792,"type":793},"2026-06-30","ACTUAL",{"date":795,"type":793},"2023-09-15",{"date":797,"type":777},"2032-03",{"name":5,"class":6},71]