[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100610770":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":30,"locations":36,"responsibleParty":50,"collaborators":26,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":58,"acronym":26,"eligibilityCriteria":59,"healthyVolunteers":56,"sex":60,"minAge":61,"maxAge":26,"enrollmentInfo":62,"targetDuration":26,"studyType":65,"phases":66,"briefSummary":69,"conditions":70,"keywords":72,"overallStatus":74,"whyStopped":26,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Assaf-Harofeh Medical Center","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Sodium bicarbonate","EXPERIMENTAL","PO Sodium bicarbonate 500mg X2\u002Fday",[13],"Drug: Sodium Bicarbonate (NaHCO3)",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","1 tab X2\u002Fday",[19],"Drug: Placebo",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Sodium Bicarbonate (NaHCO3)","Prescribing Sodium Bicaronate for intra-dualytic hypertension",[9],null,{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"1 tab X 2\u002Fday",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":26,"email":35},"Shani Zilberman Itskovich, Dr.","CONTACT","+97289779383","shani.zilberman@mail.huji.ac.il",[37],{"facility":38,"status":26,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":26},"Shamir medical center","Ẕerifin","Is","70300","Israel","IL",{"type":45,"coordinates":46},"Point",[47,48],34.84852,31.95731,{"lat":48,"lon":47},{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Shani Zilberman Itskovich","Dr.","100610770","phase-2-sodium-bicarbonate-in-intra-dialytic-hypertension-in-chronic-hemodialysis-patients-100610770",false,"NCT07231900","Sodium Bicarbonate in Intra-dialytic Hypertension in Chronic Hemodialysis Patients","Inclusion Criteria:\n\n* Chronic hemodialysis patient \\> 3 months\n* 3 dialysis per week, KTV\\>1.2\n* capable of informed concent.\n* rise in blood pressure during hemodialysis \\> 10 mm Hg, for at least 50% of dialysis sessions in the month prior to inclusion.\n* Normal volume status, by clinical physician assessment + bioimpedance\n\nExclusion Criteria:\n\n* age under 18,\n* pregnancy\n* unable to sign informed concent\n* planned for kidney transplant in the following 3 month.\n* congestive heart failure (NYHA 3-4)\n* hospitalization for acute MI or CHF in the past 3 months.\n* low compliece to medical therapy\n* regular pre-dialysis tests with bicarbonate \\> 24 in the past 3 months","ALL","18 Years",{"count":63,"type":64},40,"ESTIMATED","INTERVENTIONAL",[67,68],"PHASE2","PHASE3","The study is designed to diminish intra-dialytic hypertension in chrnic hemodialysis patients suffering from metabolic acidosis (low bicarbonate levels). The intervention is a tab of 500 mg sodium bicarbonate twice a day for one month, vs. placebo.",[71],"Hypertension in Dialysis Patients",[73],"Intra-dialytic hypertension","NOT_YET_RECRUITING","2025-11-14",{"date":77,"type":78},"2025-11-17","ACTUAL",{"date":80,"type":64},"2025-11-10",{"date":82,"type":64},"2027-12-01",{"name":5,"class":6},1]