[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100541959":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":28,"centralContacts":32,"locations":37,"responsibleParty":55,"collaborators":24,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":61,"acronym":24,"eligibilityCriteria":62,"healthyVolunteers":59,"sex":63,"minAge":64,"maxAge":24,"enrollmentInfo":65,"targetDuration":24,"studyType":68,"phases":69,"briefSummary":72,"conditions":73,"keywords":24,"overallStatus":40,"whyStopped":24,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"M.D. Anderson Cancer Center","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Group 1: SPOT-ON","EXPERIMENTAL","Participants will work with the healthcare team to find the best ways to reduce your shortness of breath by finding what combination of treatments work for participant. Participants will receive education about shortness of breath by the research staff in addition to information about standard treatments or medications for your shortness of breath that would be offered by your medical team.",[13,14],"Behavioral: SPOT-ON Early Start","Behavioral: SPOT-ON Delayed Start",{"label":16,"type":10,"description":11,"interventionNames":17},"Group 2: SPOT-ON Waitlist",[13,14],[19,25],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL","SPOT-ON Early Start","Participants will start treatment within 3 days of enrollment, which may include: receiving information on breathing techniques, relaxation techniques, posture techniques, and distraction techniques, and\u002For trying different oxygen-based therapies, such as high-flow nasal cannula, low-flow supplemental oxygen, and non-invasive ventilation with a respiratory therapist.",[9,16],null,{"type":20,"name":26,"description":22,"armGroupLabels":27,"otherNames":24},"SPOT-ON Delayed Start",[9,16],[29],{"name":30,"affiliation":5,"role":31},"David Hui, MD","PRINCIPAL_INVESTIGATOR",[33],{"name":30,"role":34,"phone":35,"phoneExt":24,"email":36},"CONTACT","(713) 792-6258","dhui@mdanderson.org",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"MD Anderson Cancer Center","RECRUITING","Houston","Texas","77030","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-95.36327,29.76328,{"lat":50,"lon":49},[53],{"name":30,"role":34,"phone":54,"phoneExt":24,"email":36},"713-792-6258",{"type":56,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100541959","phase-2-structured-personalized-oxygen-and-supportive-therapies-for-dyspnea-in-oncology-100541959",false,"NCT06336642","Structured Personalized Oxygen and Supportive Therapies for Dyspnea in Oncology","Inclusion Criteria:\n\n* Diagnosis of cancer\n* Age 18 or older.\n* Admitted to a medical floor.\n* Dyspnea intensity at rest of at least 4 on a 0-10-point NRS (where 0 = none, 10 = worst).\n* Speak English or Spanish.\n\nExclusion Criteria:\n\n* Hemodynamic instability requiring active Merit Team or ICU team involvement.\n* Delirium as per clinical team's assessment in the Electronic Health Record (EHR).\n* Severe hypoxemia (SpO2 \\\u003C 90% despite supplemental oxygen of up to 6 L\u002Fmin).\n* Continuous positive airway pressure (CPAP) use for obstructive sleep apnea, actively using \\>10 hours a day.\n* Respiratory failure necessitating mechanical ventilation (i.e., HFNC or NIV), and planned thoracentesis within 72 hours of enrollment.\n* Patients with known pregnancy.","ALL","18 Years",{"count":66,"type":67},150,"ESTIMATED","INTERVENTIONAL",[70,71],"PHASE2","PHASE3","To learn about the effect of Structured Personalized Oxygen and Supportive Therapies for Dyspnea in Oncology (SPOT-ON) treatment on the severity of shortness of breath in patients with cancer.",[74],"Dyspnea","2026-03-09",{"date":77,"type":78},"2026-03-10","ACTUAL",{"date":80,"type":78},"2024-06-11",{"date":82,"type":67},"2032-03-31",{"name":5,"class":6},1]