[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100551903":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":39,"responsibleParty":529,"collaborators":25,"id":531,"slug":532,"hasResults":533,"nctId":534,"briefTitle":535,"officialTitle":536,"acronym":25,"eligibilityCriteria":537,"healthyVolunteers":533,"sex":538,"minAge":539,"maxAge":540,"enrollmentInfo":541,"targetDuration":25,"studyType":544,"phases":545,"briefSummary":547,"conditions":548,"keywords":554,"overallStatus":42,"whyStopped":25,"lastUpdateSubmitDate":560,"lastUpdatePostDateStruct":561,"startDateStruct":564,"completionDateStruct":566,"leadSponsor":568,"locationsCount":569},{"fullName":5,"class":6},"Walden Biosciences","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"WAL0921","EXPERIMENTAL","Intravenous infusion of investigational drug WAL0921",[13],"Drug: WAL0921",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","Intravenous infusion of normal saline",[19],"Drug: Placebo",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Investigational drug WAL0921 Participants receive an intravenous infusion of WAL0921 investigational drug once every 2 weeks for 7 total infusions.",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Placebo product Participants receive an intravenous infusion of placebo once every 2 weeks for 7 total infusions.",[15],[30],{"name":31,"affiliation":5,"role":32},"Andrew Blair, MD","STUDY_DIRECTOR",[34],{"name":35,"role":36,"phone":37,"phoneExt":25,"email":38},"Michelle Skupien","CONTACT","8573141961","clinicaltrials@waldenbiosciences.com",[40,54,64,74,84,94,104,114,120,129,144,156,168,178,187,197,203,213,217,227,236,246,256,266,272,282,291,301,311,318,326,332,342,352,361,371,380,389,398,407,416,428,437,446,455,464,479,492,504,516],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":25},"Academic Medical Research Institute","RECRUITING","Los Angeles","California","90022","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-118.24368,34.05223,{"lat":52,"lon":51},{"facility":55,"status":42,"city":56,"state":57,"zip":58,"country":46,"countryCode":47,"cosmosGeoPoint":59,"geoPoint":63,"contacts":25},"Colorado Kidney and Vascular Care","Denver","Colorado","80012",{"type":49,"coordinates":60},[61,62],-104.9847,39.73915,{"lat":62,"lon":61},{"facility":65,"status":42,"city":66,"state":67,"zip":68,"country":46,"countryCode":47,"cosmosGeoPoint":69,"geoPoint":73,"contacts":25},"D & H Tamarac Research Center","Tamarac","Florida","33321",{"type":49,"coordinates":70},[71,72],-80.24977,26.21286,{"lat":72,"lon":71},{"facility":75,"status":42,"city":76,"state":77,"zip":78,"country":46,"countryCode":47,"cosmosGeoPoint":79,"geoPoint":83,"contacts":25},"Fides Clinical Research","Atlanta","Georgia","30342",{"type":49,"coordinates":80},[81,82],-84.38798,33.749,{"lat":82,"lon":81},{"facility":85,"status":42,"city":86,"state":87,"zip":88,"country":46,"countryCode":47,"cosmosGeoPoint":89,"geoPoint":93,"contacts":25},"Nephrology Associates of Northern Illinois and Indiana (NANI)","Hinsdale","Illinois","60521",{"type":49,"coordinates":90},[91,92],-87.93701,41.80086,{"lat":92,"lon":91},{"facility":95,"status":42,"city":96,"state":97,"zip":98,"country":46,"countryCode":47,"cosmosGeoPoint":99,"geoPoint":103,"contacts":25},"Dunes Clinical Research","Dakota Dunes","South Dakota","57049",{"type":49,"coordinates":100},[101,102],-96.48642,42.48749,{"lat":102,"lon":101},{"facility":105,"status":42,"city":106,"state":107,"zip":108,"country":46,"countryCode":47,"cosmosGeoPoint":109,"geoPoint":113,"contacts":25},"Prolato Clinical Research Center","Houston","Texas","77054",{"type":49,"coordinates":110},[111,112],-95.36327,29.76328,{"lat":112,"lon":111},{"facility":115,"status":42,"city":106,"state":107,"zip":116,"country":46,"countryCode":47,"cosmosGeoPoint":117,"geoPoint":119,"contacts":25},"Clinical Trial Network","77074",{"type":49,"coordinates":118},[111,112],{"lat":112,"lon":111},{"facility":121,"status":42,"city":122,"state":107,"zip":123,"country":46,"countryCode":47,"cosmosGeoPoint":124,"geoPoint":128,"contacts":25},"Clinical Advancement Center","San Antonio","78212",{"type":49,"coordinates":125},[126,127],-98.49363,29.42412,{"lat":127,"lon":126},{"facility":130,"status":42,"city":131,"state":132,"zip":133,"country":134,"countryCode":135,"cosmosGeoPoint":136,"geoPoint":140,"contacts":141},"Westmead Hospital","Westmead","New South Wales","2145","Australia","AU",{"type":49,"coordinates":137},[138,139],150.98768,-33.80383,{"lat":139,"lon":138},[142],{"name":35,"role":36,"phone":143,"phoneExt":25,"email":38},"+18573141961",{"facility":145,"status":42,"city":146,"state":147,"zip":148,"country":134,"countryCode":135,"cosmosGeoPoint":149,"geoPoint":153,"contacts":154},"Western Health Sunshine Hospital","St Albans","Victoria","3021",{"type":49,"coordinates":150},[151,152],144.80049,-37.74496,{"lat":152,"lon":151},[155],{"name":35,"role":36,"phone":143,"phoneExt":25,"email":38},{"facility":157,"status":42,"city":158,"state":159,"zip":160,"country":161,"countryCode":162,"cosmosGeoPoint":163,"geoPoint":167,"contacts":25},"AIIMS Hospital","Raipur","Chhattisgarh","492099","India","IN",{"type":49,"coordinates":164},[165,166],81.63333,21.23333,{"lat":166,"lon":165},{"facility":169,"status":42,"city":170,"state":171,"zip":172,"country":161,"countryCode":162,"cosmosGeoPoint":173,"geoPoint":177,"contacts":25},"Muljibhai Patel Urological Hospital","Nadiād","Gujarat","387003",{"type":49,"coordinates":174},[175,176],72.86157,22.69385,{"lat":176,"lon":175},{"facility":179,"status":42,"city":180,"state":171,"zip":181,"country":161,"countryCode":162,"cosmosGeoPoint":182,"geoPoint":186,"contacts":25},"Dhiraj Hospital","Vadodara","391760",{"type":49,"coordinates":183},[184,185],73.20812,22.29941,{"lat":185,"lon":184},{"facility":188,"status":42,"city":189,"state":190,"zip":191,"country":161,"countryCode":162,"cosmosGeoPoint":192,"geoPoint":196,"contacts":25},"MS Ramaiah Medical College and Hospitals","Bangalore","Karnataka","560054",{"type":49,"coordinates":193},[194,195],77.59369,12.97194,{"lat":195,"lon":194},{"facility":198,"status":42,"city":189,"state":190,"zip":199,"country":161,"countryCode":162,"cosmosGeoPoint":200,"geoPoint":202,"contacts":25},"Mazumdar Shah Medical Center","560099",{"type":49,"coordinates":201},[194,195],{"lat":195,"lon":194},{"facility":204,"status":42,"city":205,"state":206,"zip":207,"country":161,"countryCode":162,"cosmosGeoPoint":208,"geoPoint":212,"contacts":25},"Manipal Hospital","Pune","Maharashtra","411045",{"type":49,"coordinates":209},[210,211],73.85535,18.51957,{"lat":211,"lon":210},{"facility":214,"status":42,"city":215,"state":206,"zip":216,"country":161,"countryCode":162,"cosmosGeoPoint":25,"geoPoint":25,"contacts":25},"MGM Medical Care and Hospital","Sambhajinagar","431003",{"facility":218,"status":42,"city":219,"state":220,"zip":221,"country":161,"countryCode":162,"cosmosGeoPoint":222,"geoPoint":226,"contacts":25},"Sir Ganga Ram Hospital","New Delhi","National Capital Territory of Delhi","110060",{"type":49,"coordinates":223},[224,225],77.2148,28.62137,{"lat":225,"lon":224},{"facility":228,"status":42,"city":229,"state":220,"zip":230,"country":161,"countryCode":162,"cosmosGeoPoint":231,"geoPoint":235,"contacts":25},"Max Super Speciality Hospital","Patparganj","110092",{"type":49,"coordinates":232},[233,234],77.29528,28.60902,{"lat":234,"lon":233},{"facility":237,"status":42,"city":238,"state":239,"zip":240,"country":161,"countryCode":162,"cosmosGeoPoint":241,"geoPoint":245,"contacts":25},"SUM Hospital","Bhubaneswar","Odisha","751029",{"type":49,"coordinates":242},[243,244],85.83385,20.27241,{"lat":244,"lon":243},{"facility":247,"status":42,"city":248,"state":249,"zip":250,"country":161,"countryCode":162,"cosmosGeoPoint":251,"geoPoint":255,"contacts":25},"SMS Medical College and Hospital","Jaipur","Rajasthan","302004",{"type":49,"coordinates":252},[253,254],75.78781,26.91962,{"lat":254,"lon":253},{"facility":257,"status":42,"city":258,"state":259,"zip":260,"country":161,"countryCode":162,"cosmosGeoPoint":261,"geoPoint":265,"contacts":25},"Osmania General Hospital","Hyderabad","Telangana","500012",{"type":49,"coordinates":262},[263,264],78.45636,17.38405,{"lat":264,"lon":263},{"facility":267,"status":42,"city":258,"state":259,"zip":268,"country":161,"countryCode":162,"cosmosGeoPoint":269,"geoPoint":271,"contacts":25},"Nizam's Institute of Medical Sciences","500082",{"type":49,"coordinates":270},[263,264],{"lat":264,"lon":263},{"facility":273,"status":42,"city":274,"state":275,"zip":276,"country":161,"countryCode":162,"cosmosGeoPoint":277,"geoPoint":281,"contacts":25},"Sanjay Gandhi Post Graduate Institute of Medical Sciences","Lucknow","Uttar Pradesh","226014",{"type":49,"coordinates":278},[279,280],80.92313,26.83928,{"lat":280,"lon":279},{"facility":283,"status":42,"city":284,"state":275,"zip":285,"country":161,"countryCode":162,"cosmosGeoPoint":286,"geoPoint":290,"contacts":25},"Nutema Hospital","Meerut","250002",{"type":49,"coordinates":287},[288,289],77.70636,28.98002,{"lat":289,"lon":288},{"facility":292,"status":42,"city":293,"state":294,"zip":295,"country":161,"countryCode":162,"cosmosGeoPoint":296,"geoPoint":300,"contacts":25},"Shri Guru Ram Rai Institute of Medical and Health Sciences","Dehradun","Uttarakhand","248001",{"type":49,"coordinates":297},[298,299],78.03392,30.32443,{"lat":299,"lon":298},{"facility":302,"status":42,"city":303,"state":304,"zip":305,"country":161,"countryCode":162,"cosmosGeoPoint":306,"geoPoint":310,"contacts":25},"NRS Medical College and Hospital Kolkata","Kolkata","West Bengal","700014",{"type":49,"coordinates":307},[308,309],88.36304,22.56263,{"lat":309,"lon":308},{"facility":312,"status":42,"city":313,"state":314,"zip":315,"country":316,"countryCode":317,"cosmosGeoPoint":25,"geoPoint":25,"contacts":25},"Hospital Canselor Tuanku Muhriz UKM","Cheras","Kuala Lumpur","56000","Malaysia","MY",{"facility":319,"status":42,"city":314,"state":314,"zip":320,"country":316,"countryCode":317,"cosmosGeoPoint":321,"geoPoint":325,"contacts":25},"Hospital Kuala Lumpur","50586",{"type":49,"coordinates":322},[323,324],101.68653,3.1412,{"lat":324,"lon":323},{"facility":327,"status":42,"city":314,"state":314,"zip":328,"country":316,"countryCode":317,"cosmosGeoPoint":329,"geoPoint":331,"contacts":25},"University Malaya Medical Centre","50603",{"type":49,"coordinates":330},[323,324],{"lat":324,"lon":323},{"facility":333,"status":42,"city":334,"state":335,"zip":336,"country":316,"countryCode":317,"cosmosGeoPoint":337,"geoPoint":341,"contacts":25},"Hospital Tengku Ampuan Afzan","Kuantan","Pahang","25100",{"type":49,"coordinates":338},[339,340],103.326,3.8077,{"lat":340,"lon":339},{"facility":343,"status":42,"city":344,"state":345,"zip":346,"country":316,"countryCode":317,"cosmosGeoPoint":347,"geoPoint":351,"contacts":25},"Hospital Sultan Idris Shah Serdang","Kajang","Selangor","43000",{"type":49,"coordinates":348},[349,350],101.78875,2.99424,{"lat":350,"lon":349},{"facility":353,"status":42,"city":354,"state":345,"zip":355,"country":316,"countryCode":317,"cosmosGeoPoint":356,"geoPoint":360,"contacts":25},"Sunway Medical Centre","Petaling Jaya","47500",{"type":49,"coordinates":357},[358,359],101.60671,3.10726,{"lat":359,"lon":358},{"facility":362,"status":42,"city":363,"state":25,"zip":364,"country":365,"countryCode":25,"cosmosGeoPoint":366,"geoPoint":370,"contacts":25},"Hallym University Sacred Heart Hospital","Anyang","14068","South Korea",{"type":49,"coordinates":367},[368,369],127.49001,35.62128,{"lat":369,"lon":368},{"facility":372,"status":42,"city":373,"state":25,"zip":374,"country":365,"countryCode":25,"cosmosGeoPoint":375,"geoPoint":379,"contacts":25},"Pusan National University Hospital","Busan","49241",{"type":49,"coordinates":376},[377,378],129.03004,35.10168,{"lat":378,"lon":377},{"facility":381,"status":42,"city":382,"state":25,"zip":383,"country":365,"countryCode":25,"cosmosGeoPoint":384,"geoPoint":388,"contacts":25},"Seoul National University Bundang Hospital","Seongnam-si","13620",{"type":49,"coordinates":385},[386,387],127.13778,37.43861,{"lat":387,"lon":386},{"facility":390,"status":42,"city":391,"state":25,"zip":392,"country":365,"countryCode":25,"cosmosGeoPoint":393,"geoPoint":397,"contacts":25},"Severance Hospital - Yonsei Cancer Center","Seoul","03722",{"type":49,"coordinates":394},[395,396],126.9784,37.566,{"lat":396,"lon":395},{"facility":399,"status":42,"city":400,"state":25,"zip":401,"country":365,"countryCode":25,"cosmosGeoPoint":402,"geoPoint":406,"contacts":25},"Samsung Medical Center","Soeul","06351",{"type":49,"coordinates":403},[404,405],126.7319,36.9168,{"lat":405,"lon":404},{"facility":408,"status":42,"city":409,"state":25,"zip":410,"country":365,"countryCode":25,"cosmosGeoPoint":411,"geoPoint":415,"contacts":25},"Ajou University Hospital","Suwon","16499",{"type":49,"coordinates":412},[413,414],127.00889,37.29111,{"lat":414,"lon":413},{"facility":417,"status":418,"city":419,"state":25,"zip":420,"country":421,"countryCode":422,"cosmosGeoPoint":423,"geoPoint":427,"contacts":25},"National Hospital of Sri Lanka","NOT_YET_RECRUITING","Colombo","00700","Sri Lanka","LK",{"type":49,"coordinates":424},[425,426],79.84868,6.93548,{"lat":426,"lon":425},{"facility":429,"status":418,"city":430,"state":25,"zip":431,"country":421,"countryCode":422,"cosmosGeoPoint":432,"geoPoint":436,"contacts":25},"Jaffna Teaching Hospital","Jaffna","40000",{"type":49,"coordinates":433},[434,435],80.00742,9.66845,{"lat":435,"lon":434},{"facility":438,"status":418,"city":439,"state":25,"zip":440,"country":421,"countryCode":422,"cosmosGeoPoint":441,"geoPoint":445,"contacts":25},"Kandy National Hospital","Kandy","20000",{"type":49,"coordinates":442},[443,444],80.6336,7.2906,{"lat":444,"lon":443},{"facility":447,"status":418,"city":448,"state":25,"zip":449,"country":421,"countryCode":422,"cosmosGeoPoint":450,"geoPoint":454,"contacts":25},"Kurunegala Teaching Hospital","Kurunegala","60000",{"type":49,"coordinates":451},[452,453],80.3683,7.4839,{"lat":453,"lon":452},{"facility":456,"status":418,"city":457,"state":25,"zip":458,"country":421,"countryCode":422,"cosmosGeoPoint":459,"geoPoint":463,"contacts":25},"Kothalawala Defence University Hospital","Werahera","10290",{"type":49,"coordinates":460},[461,462],80.0095,7.3759,{"lat":462,"lon":461},{"facility":465,"status":418,"city":466,"state":25,"zip":467,"country":468,"countryCode":469,"cosmosGeoPoint":470,"geoPoint":474,"contacts":475},"Royal Derby Hospital","Derby","DE22 3NE","United Kingdom","UK",{"type":49,"coordinates":471},[472,473],-1.47663,52.92277,{"lat":473,"lon":472},[476],{"name":477,"role":36,"phone":478,"phoneExt":25,"email":38},"Michelle Skupian","+1 857 314 1961",{"facility":480,"status":418,"city":481,"state":25,"zip":482,"country":468,"countryCode":469,"cosmosGeoPoint":483,"geoPoint":487,"contacts":488},"College of Life Sciences, University of Leicester","Leicester","LE1 7RH",{"type":49,"coordinates":484},[485,486],-1.13169,52.6386,{"lat":486,"lon":485},[489,490],{"name":477,"role":36,"phone":25,"phoneExt":25,"email":25},{"name":25,"role":36,"phone":491,"phoneExt":25,"email":38},"+1 8573141961",{"facility":493,"status":418,"city":494,"state":25,"zip":495,"country":468,"countryCode":469,"cosmosGeoPoint":496,"geoPoint":500,"contacts":501},"Barts Health NHS Trust","London","E1 2ES",{"type":49,"coordinates":497},[498,499],-0.12574,51.50853,{"lat":499,"lon":498},[502,503],{"name":477,"role":36,"phone":25,"phoneExt":25,"email":25},{"name":25,"role":36,"phone":491,"phoneExt":25,"email":38},{"facility":505,"status":418,"city":506,"state":25,"zip":507,"country":468,"countryCode":469,"cosmosGeoPoint":508,"geoPoint":512,"contacts":513},"Manchester University NHS Foundation Trust","Manchester","M13 9WL",{"type":49,"coordinates":509},[510,511],-2.23743,53.48095,{"lat":511,"lon":510},[514,515],{"name":477,"role":36,"phone":25,"phoneExt":25,"email":25},{"name":25,"role":36,"phone":491,"phoneExt":25,"email":38},{"facility":517,"status":418,"city":518,"state":25,"zip":519,"country":468,"countryCode":469,"cosmosGeoPoint":520,"geoPoint":524,"contacts":525},"Salford Royal NHS Foundation Trust","Salford","M6 8HD",{"type":49,"coordinates":521},[522,523],-2.29042,53.48771,{"lat":523,"lon":522},[526,528],{"name":527,"role":36,"phone":25,"phoneExt":25,"email":25},"michelle Skupian",{"name":25,"role":36,"phone":491,"phoneExt":25,"email":38},{"type":530,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100551903","phase-2-study-of-wal0921-in-patients-with-glomerular-kidney-diseases-100551903",false,"NCT06466135","Study of WAL0921 in Patients With Glomerular Kidney Diseases","Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of WAL0921 in Patients With Glomerular Kidney Diseases and Proteinuria","Inclusion Criteria:\n\n* Adults, age 18-75 years\n* Diagnosis of one of the following glomerular kidney diseases: diabetic nephropathy; primary focal segmental glomerulosclerosis; treatment resistant-minimal change disease; primary IgA nephropathy; primary membranous nephropathy\n* eGFR greater than or equal to 30 mL\u002Fmin\u002F1.73 m2\n\nExclusion Criteria:\n\n* Currently pregnant or planning to become pregnant\n* History of organ transplantation\n* History of alcohol or substance use disorder\n* Acute dialysis or acute kidney injury within 6 months of Screening\n* Any prior or current medical condition that, in the judgment of the Investigator, would prevent the subject from safely participating in and\u002For completing all study requirements","ALL","18 Years","75 Years",{"count":542,"type":543},96,"ESTIMATED","INTERVENTIONAL",[546],"PHASE2","This is an adaptive prospective, multi-center, randomized, double-blind, placebo-controlled study to evaluate the safety, efficacy, pharmacokinetics, and pharmacodynamics of WAL0921 in subjects with glomerular kidney disease and proteinuria, including diabetic nephropathy and rare glomerular kidney diseases (primary focal segmental glomerulosclerosis \\[FSGS\\], treatment-resistant minimal change disease \\[TR MCD\\], primary immunoglobulin A nephropathy \\[IgAN\\], and primary membranous nephropathy \\[PMN\\]). Subjects in this study will be randomized to receive the investigational drug WAL0921 or placebo as an intravenous infusion once every 2 weeks for 7 total infusions. All subjects will be followed for 24 weeks after their last infusion.",[549,550,551,552,553],"Diabetic Nephropathies","Primary Focal Segmental Glomerulosclerosis","Minimal Change Disease","Primary Immunoglobulin A Nephropathy","Primary Membranous Nephropathy",[555,556,557,558,559],"DN","FSGS","TR-MCD","IgAN","PMN","2026-03-27",{"date":562,"type":563},"2026-04-02","ACTUAL",{"date":565,"type":563},"2024-07-02",{"date":567,"type":543},"2027-06",{"name":5,"class":6},50]