[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100614812":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":36,"centralContacts":40,"locations":50,"responsibleParty":489,"collaborators":11,"id":491,"slug":11,"hasResults":492,"nctId":493,"briefTitle":494,"officialTitle":495,"acronym":11,"eligibilityCriteria":496,"healthyVolunteers":492,"sex":497,"minAge":498,"maxAge":11,"enrollmentInfo":499,"targetDuration":11,"studyType":502,"phases":503,"briefSummary":505,"conditions":506,"keywords":508,"overallStatus":53,"whyStopped":11,"lastUpdateSubmitDate":514,"lastUpdatePostDateStruct":515,"startDateStruct":518,"completionDateStruct":520,"leadSponsor":522,"locationsCount":523},{"fullName":5,"class":6},"Contineum Therapeutics","INDUSTRY",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"PIPE-791 Dose A","EXPERIMENTAL",null,[13],"Drug: PIPE-791 Dose A",{"label":15,"type":10,"description":11,"interventionNames":16},"PIPE-791 Dose B",[17],"Drug: PIPE-791 Dose B",{"label":19,"type":20,"description":11,"interventionNames":21},"Placebo","PLACEBO_COMPARATOR",[22],"Drug: Placebo",[24,30,33],{"type":25,"name":9,"description":26,"armGroupLabels":27,"otherNames":28},"DRUG","Participants will receive a daily oral dose of PIPE-791 in tablet form",[9],[29],"PIPE-791",{"type":25,"name":15,"description":26,"armGroupLabels":31,"otherNames":32},[15],[29],{"type":25,"name":19,"description":34,"armGroupLabels":35,"otherNames":11},"Participants will receive a daily oral dose of matching Placebo in tablet form",[19],[37],{"name":38,"affiliation":5,"role":39},"Mudiaga O Sowho, MD, MPH","STUDY_DIRECTOR",[41,46],{"name":42,"role":43,"phone":44,"phoneExt":11,"email":45},"Nikki Nepomuceno","CONTACT","858-333-5280","nnepomuceno@contineum-tx.com",{"name":47,"role":43,"phone":48,"phoneExt":11,"email":49},"Marietta Franco","650-450-6634","mfranco@contineum-tx.com",[51,65,74,80,86,95,107,117,127,136,146,155,167,177,187,196,206,218,227,236,240,249,259,268,278,287,294,303,315,324,334,344,356,365,374,385,395,404,411,417,424,433,439,451,461,471,480],{"facility":52,"status":53,"city":54,"state":55,"zip":56,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":11},"IPR-Investigaciones en Patologías Respiratorias","RECRUITING","San Miguel de Tucumán","Tucumán Province","T4000IAP","Argentina","AR",{"type":60,"coordinates":61},"Point",[62,63],-65.21051,-26.81601,{"lat":63,"lon":62},{"facility":66,"status":53,"city":67,"state":11,"zip":68,"country":57,"countryCode":58,"cosmosGeoPoint":69,"geoPoint":73,"contacts":11},"STAT Research S.A.","Buenos Aires","C1023AAB",{"type":60,"coordinates":70},[71,72],-58.37723,-34.61315,{"lat":72,"lon":71},{"facility":75,"status":53,"city":67,"state":11,"zip":76,"country":57,"countryCode":58,"cosmosGeoPoint":77,"geoPoint":79,"contacts":11},"Consultorios Médicos Organización del Buen Ayre SRL","C1425FVH",{"type":60,"coordinates":78},[71,72],{"lat":72,"lon":71},{"facility":81,"status":53,"city":67,"state":11,"zip":82,"country":57,"countryCode":58,"cosmosGeoPoint":83,"geoPoint":85,"contacts":11},"Centro Médico Dra de Salvo - Fundacion Respirar - PPDS","C1426ABP",{"type":60,"coordinates":84},[71,72],{"lat":72,"lon":71},{"facility":87,"status":53,"city":88,"state":11,"zip":89,"country":57,"countryCode":58,"cosmosGeoPoint":90,"geoPoint":94,"contacts":11},"IbaMedica","Santa Fe","S3000ASF",{"type":60,"coordinates":91},[92,93],-60.70868,-31.64881,{"lat":93,"lon":92},{"facility":96,"status":53,"city":97,"state":98,"zip":99,"country":100,"countryCode":101,"cosmosGeoPoint":102,"geoPoint":106,"contacts":11},"Westmead Hospital","Westmead","New South Wales","2145","Australia","AU",{"type":60,"coordinates":103},[104,105],150.98768,-33.80383,{"lat":105,"lon":104},{"facility":108,"status":53,"city":109,"state":110,"zip":111,"country":100,"countryCode":101,"cosmosGeoPoint":112,"geoPoint":116,"contacts":11},"The Prince Charles Hospital","Chermside","Queensland","4032",{"type":60,"coordinates":113},[114,115],153.03062,-27.38472,{"lat":115,"lon":114},{"facility":118,"status":53,"city":119,"state":120,"zip":121,"country":100,"countryCode":101,"cosmosGeoPoint":122,"geoPoint":126,"contacts":11},"Austin Health","Heidelberg","Victoria","3084",{"type":60,"coordinates":123},[124,125],145.06667,-37.75,{"lat":125,"lon":124},{"facility":128,"status":53,"city":129,"state":120,"zip":130,"country":100,"countryCode":101,"cosmosGeoPoint":131,"geoPoint":135,"contacts":11},"The Alfred Hospital","Melbourne","3004",{"type":60,"coordinates":132},[133,134],144.96332,-37.814,{"lat":134,"lon":133},{"facility":137,"status":53,"city":138,"state":139,"zip":140,"country":100,"countryCode":101,"cosmosGeoPoint":141,"geoPoint":145,"contacts":11},"Institute for Respiratory Health","Midland","Western Australia","6056",{"type":60,"coordinates":142},[143,144],116.0107,-31.88909,{"lat":144,"lon":143},{"facility":147,"status":53,"city":148,"state":139,"zip":149,"country":100,"countryCode":101,"cosmosGeoPoint":150,"geoPoint":154,"contacts":11},"TrialsWest Pty Ltd","Spearwood","6163",{"type":60,"coordinates":151},[152,153],115.77797,-32.10534,{"lat":153,"lon":152},{"facility":156,"status":53,"city":157,"state":158,"zip":159,"country":160,"countryCode":161,"cosmosGeoPoint":162,"geoPoint":166,"contacts":11},"Vancouver General Hospital","Vancouver","British Columbia","V5Z 1M9","Canada","CA",{"type":60,"coordinates":163},[164,165],-123.11934,49.24966,{"lat":165,"lon":164},{"facility":168,"status":53,"city":169,"state":170,"zip":171,"country":160,"countryCode":161,"cosmosGeoPoint":172,"geoPoint":176,"contacts":11},"Toronto General Hospital","Toronto","Ontaria","M5G 2C4",{"type":60,"coordinates":173},[174,175],-79.39864,43.70643,{"lat":175,"lon":174},{"facility":178,"status":53,"city":179,"state":180,"zip":181,"country":160,"countryCode":161,"cosmosGeoPoint":182,"geoPoint":186,"contacts":11},"Dynamic Drug Advancement Ltd.","Ajax","Ontario","L1S 2J5",{"type":60,"coordinates":183},[184,185],-79.03288,43.85012,{"lat":185,"lon":184},{"facility":188,"status":53,"city":189,"state":180,"zip":190,"country":160,"countryCode":161,"cosmosGeoPoint":191,"geoPoint":195,"contacts":11},"Dr. Anil Dhar Medicine Professional Corporation","Windsor","N8X 5A6",{"type":60,"coordinates":192},[193,194],-83.01654,42.30008,{"lat":194,"lon":193},{"facility":197,"status":53,"city":198,"state":199,"zip":200,"country":160,"countryCode":161,"cosmosGeoPoint":201,"geoPoint":205,"contacts":11},"Centre d'investigation Clinique Mauricie","Trois-Rivières","Quebec","G8T 7A1",{"type":60,"coordinates":202},[203,204],-72.5477,46.34515,{"lat":204,"lon":203},{"facility":207,"status":53,"city":208,"state":209,"zip":210,"country":211,"countryCode":212,"cosmosGeoPoint":213,"geoPoint":217,"contacts":11},"Shamir Medical Center","Be’er Ya‘aqov","Central District","7033001","Israel","IL",{"type":60,"coordinates":214},[215,216],34.83749,31.93864,{"lat":216,"lon":215},{"facility":219,"status":53,"city":220,"state":209,"zip":221,"country":211,"countryCode":212,"cosmosGeoPoint":222,"geoPoint":226,"contacts":11},"Meir Medical Center","Kafr Saba","4428164",{"type":60,"coordinates":223},[224,225],34.90694,32.175,{"lat":225,"lon":224},{"facility":228,"status":53,"city":229,"state":209,"zip":230,"country":211,"countryCode":212,"cosmosGeoPoint":231,"geoPoint":235,"contacts":11},"Rabin Medical Center - PPDS","Petah Tikva","4941492",{"type":60,"coordinates":232},[233,234],34.88747,32.08707,{"lat":234,"lon":233},{"facility":237,"status":53,"city":238,"state":209,"zip":239,"country":211,"countryCode":212,"cosmosGeoPoint":11,"geoPoint":11,"contacts":11},"The Chaim Sheba Medical Center - PPDS","Ramat Gan","5262100",{"facility":241,"status":53,"city":242,"state":209,"zip":243,"country":211,"countryCode":212,"cosmosGeoPoint":244,"geoPoint":248,"contacts":11},"Kaplan Medical Center","Rehovot","7661041",{"type":60,"coordinates":245},[246,247],34.81199,31.89421,{"lat":247,"lon":246},{"facility":250,"status":53,"city":251,"state":252,"zip":253,"country":211,"countryCode":212,"cosmosGeoPoint":254,"geoPoint":258,"contacts":11},"Hillel Yaffe Medical Center","Hadera","Haifa District","3820302",{"type":60,"coordinates":255},[256,257],34.9039,32.44192,{"lat":257,"lon":256},{"facility":260,"status":53,"city":261,"state":261,"zip":262,"country":211,"countryCode":212,"cosmosGeoPoint":263,"geoPoint":267,"contacts":11},"Hadassah Medical Center- Ein Kerem - PPDS","Jerusalem","9112001",{"type":60,"coordinates":264},[265,266],35.21633,31.76904,{"lat":266,"lon":265},{"facility":269,"status":53,"city":270,"state":271,"zip":272,"country":211,"countryCode":212,"cosmosGeoPoint":273,"geoPoint":277,"contacts":11},"Assuta Ashdod University Medical Center","Ashdod","Southern District","7747629",{"type":60,"coordinates":274},[275,276],34.64966,31.79213,{"lat":276,"lon":275},{"facility":279,"status":53,"city":280,"state":271,"zip":281,"country":211,"countryCode":212,"cosmosGeoPoint":282,"geoPoint":286,"contacts":11},"The Barzilai University Medical Center","Ashkelon","7830604",{"type":60,"coordinates":283},[284,285],34.57149,31.66926,{"lat":285,"lon":284},{"facility":288,"status":53,"city":261,"state":289,"zip":290,"country":211,"countryCode":212,"cosmosGeoPoint":291,"geoPoint":293,"contacts":11},"Shaare Zedek Medical Center","Yerushala","9103102",{"type":60,"coordinates":292},[265,266],{"lat":266,"lon":265},{"facility":295,"status":53,"city":296,"state":11,"zip":297,"country":211,"countryCode":212,"cosmosGeoPoint":298,"geoPoint":302,"contacts":11},"Tel Aviv Sourasky Medical Center Ichilov - PPDS","Tel Aviv","6423906",{"type":60,"coordinates":299},[300,301],34.78057,32.08088,{"lat":301,"lon":300},{"facility":304,"status":53,"city":305,"state":306,"zip":307,"country":308,"countryCode":309,"cosmosGeoPoint":310,"geoPoint":314,"contacts":11},"Greenlane Clinical Centre","Epsom","Auckland","1051","New Zealand","NZ",{"type":60,"coordinates":311},[312,313],174.77059,-36.88745,{"lat":313,"lon":312},{"facility":316,"status":53,"city":317,"state":306,"zip":318,"country":308,"countryCode":309,"cosmosGeoPoint":319,"geoPoint":323,"contacts":11},"Aotearoa Clinical Trials Trust - Middlemore Hospital - PPDS","Papatoetoe","2025",{"type":60,"coordinates":320},[321,322],174.84019,-36.9682,{"lat":322,"lon":321},{"facility":325,"status":53,"city":326,"state":327,"zip":328,"country":308,"countryCode":309,"cosmosGeoPoint":329,"geoPoint":333,"contacts":11},"Canterbury Respiratory Research Group","Christchurch","Canterbury","8001",{"type":60,"coordinates":330},[331,332],172.63333,-43.53333,{"lat":332,"lon":331},{"facility":335,"status":53,"city":336,"state":337,"zip":338,"country":308,"countryCode":309,"cosmosGeoPoint":339,"geoPoint":343,"contacts":11},"Health New Zealand - Te Whatu Ora - Waikato Hospital","Hamilton","Waikato Region","3240",{"type":60,"coordinates":340},[341,342],175.28333,-37.78333,{"lat":342,"lon":341},{"facility":345,"status":53,"city":346,"state":347,"zip":348,"country":349,"countryCode":350,"cosmosGeoPoint":351,"geoPoint":355,"contacts":11},"Institute of Pulmonary Diseases of Vojvodina","Kamenitz","Syrmia","21204","Serbia","RS",{"type":60,"coordinates":352},[353,354],19.84263,45.22334,{"lat":354,"lon":353},{"facility":357,"status":53,"city":358,"state":11,"zip":359,"country":349,"countryCode":350,"cosmosGeoPoint":360,"geoPoint":364,"contacts":11},"University Clinical Center of Serbia - Koste Todorovica - PPDS","Belgrade","11000",{"type":60,"coordinates":361},[362,363],20.46513,44.80401,{"lat":363,"lon":362},{"facility":366,"status":53,"city":367,"state":11,"zip":368,"country":349,"countryCode":350,"cosmosGeoPoint":369,"geoPoint":373,"contacts":11},"University Clinical Center Kragujevac","Kragujevac","34000",{"type":60,"coordinates":370},[371,372],20.91667,44.01667,{"lat":372,"lon":371},{"facility":375,"status":53,"city":376,"state":377,"zip":378,"country":379,"countryCode":11,"cosmosGeoPoint":380,"geoPoint":384,"contacts":11},"The Catholic University of Korea - Eunpyeong St. Mary's Hospital","Seoul","Eunpyeong District","03312","South Korea",{"type":60,"coordinates":381},[382,383],126.9784,37.566,{"lat":383,"lon":382},{"facility":386,"status":53,"city":387,"state":388,"zip":389,"country":379,"countryCode":11,"cosmosGeoPoint":390,"geoPoint":394,"contacts":11},"The Catholic University of Korea, Bucheon St. Mary's Hospital","Bucheon-si","Gyeonggi-do","14647",{"type":60,"coordinates":391},[392,393],126.78306,37.49889,{"lat":393,"lon":392},{"facility":396,"status":53,"city":397,"state":388,"zip":398,"country":379,"countryCode":11,"cosmosGeoPoint":399,"geoPoint":403,"contacts":11},"Seoul National University Bundang Hospital","Seongnam-si","13620",{"type":60,"coordinates":400},[401,402],127.13778,37.43861,{"lat":402,"lon":401},{"facility":405,"status":53,"city":376,"state":406,"zip":407,"country":379,"countryCode":11,"cosmosGeoPoint":408,"geoPoint":410,"contacts":11},"Severance Hospital Yonsei University Health System","Seodaemun","03722",{"type":60,"coordinates":409},[382,383],{"lat":383,"lon":382},{"facility":412,"status":53,"city":376,"state":376,"zip":413,"country":379,"countryCode":11,"cosmosGeoPoint":414,"geoPoint":416,"contacts":11},"Samsung Medical Center","06351",{"type":60,"coordinates":415},[382,383],{"lat":383,"lon":382},{"facility":418,"status":53,"city":376,"state":419,"zip":420,"country":379,"countryCode":11,"cosmosGeoPoint":421,"geoPoint":423,"contacts":11},"Soon Chun Hyang University Hospital","Yongsan-gu","04401",{"type":60,"coordinates":422},[382,383],{"lat":383,"lon":382},{"facility":425,"status":53,"city":426,"state":11,"zip":427,"country":379,"countryCode":11,"cosmosGeoPoint":428,"geoPoint":432,"contacts":11},"Gachon University Gil Medical Center","Incheon","21565",{"type":60,"coordinates":429},[430,431],126.70515,37.45646,{"lat":431,"lon":430},{"facility":434,"status":53,"city":376,"state":11,"zip":435,"country":379,"countryCode":11,"cosmosGeoPoint":436,"geoPoint":438,"contacts":11},"Korea University Anam Hospital","2841",{"type":60,"coordinates":437},[382,383],{"lat":383,"lon":382},{"facility":440,"status":53,"city":441,"state":442,"zip":443,"country":444,"countryCode":445,"cosmosGeoPoint":446,"geoPoint":450,"contacts":11},"NIHR Leicester Biomedical Research Centre - Glenfield Hospital","Leicester","England","LE3 9QP","United Kingdom","UK",{"type":60,"coordinates":447},[448,449],-1.13169,52.6386,{"lat":449,"lon":448},{"facility":452,"status":53,"city":453,"state":454,"zip":455,"country":444,"countryCode":445,"cosmosGeoPoint":456,"geoPoint":460,"contacts":11},"Southampton General Hospital","Southampton","Hampshire","SO16 6YD",{"type":60,"coordinates":457},[458,459],-1.40428,50.90395,{"lat":459,"lon":458},{"facility":462,"status":53,"city":463,"state":464,"zip":465,"country":444,"countryCode":445,"cosmosGeoPoint":466,"geoPoint":470,"contacts":11},"Royal Infirmary of Edinburgh","Edinburgh","Scotland","EH16 4SA",{"type":60,"coordinates":467},[468,469],-3.19648,55.95206,{"lat":469,"lon":468},{"facility":472,"status":53,"city":473,"state":464,"zip":474,"country":444,"countryCode":445,"cosmosGeoPoint":475,"geoPoint":479,"contacts":11},"Perth Royal Infirmary","Perth","PH1 1NX",{"type":60,"coordinates":476},[477,478],-3.43139,56.39522,{"lat":478,"lon":477},{"facility":481,"status":53,"city":482,"state":11,"zip":483,"country":444,"countryCode":445,"cosmosGeoPoint":484,"geoPoint":488,"contacts":11},"Birmingham Heartlands Hospital","Birmingham","B3 3HX",{"type":60,"coordinates":485},[486,487],-1.89983,52.48142,{"lat":487,"lon":486},{"type":490,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100614812",false,"NCT07284459","Study to Evaluate the Efficacy, Safety, and Tolerability of PIPE 791 in Subjects With Idiopathic Pulmonary Fibrosis","A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy, Safety, and Tolerability of Oral PIPE 791 in Subjects With Idiopathic Pulmonary Fibrosis","Key Inclusion Criteria:\n\n* Male or female ≥ 40 years of age at the time of Randomization.\n* A diagnosis of IPF within 7 years prior to Screening, based on the 2022 ATS\u002FERS\u002FJRS\u002FALAT practice guideline as confirmed by the Investigator, and a centrally read screening HRCT consistent with usual interstitial pneumonia (UIP) or probable UIP.\n* Percent predicted (pp) FVC ≥ 40% on Screening spirometry.\n* Participants may enter the study whether or not they are receiving background nintedanib or pirfenidone therapy approved for the treatment of IPF, but not both concurrently.\n\nKey Exclusion Criteria:\n\n* Those with a history of interstitial lung disease (ILD) other than IPF are not eligible.\n* Those with pulmonary arterial hypertension (PAH) requiring multi-drug therapy are not eligible.\n* Those who have experienced an IPF exacerbation within 6 weeks of Screening, or during Screening, are not eligible.\n* Those with an estimated glomerular filtration rate (eGFR) ≤ 30 ml\u002Fmin\u002F1.73 m2 (Chronic Kidney Disease Epidemiology Collaboration \\[CKD-EPI\\] formula) (Inker 2021) or who have Child-Pugh Class B or C hepatic impairment are not eligible.\n* Female participants must not be of childbearing potential.\n\nAdditional inclusion and exclusion criteria apply.","ALL","40 Years",{"count":500,"type":501},324,"ESTIMATED","INTERVENTIONAL",[504],"PHASE2","This is a Ph 2, randomized, double-blind, placebo-controlled global multicenter study to evaluate the efficacy, safety, tolerability, and pharmacokinetics (PK) of PIPE-791 in participants with a diagnosis of Idiopathic Pulmonary Fibrosis (IPF) with or without background treatment.",[507],"Idiopathic Pulmonary Fibrosis",[507,509,510,511,512,513],"PIPE 791","Pulmonary Fibrosis","IPF","ILD","Interstitial lung disease","2026-06-29",{"date":516,"type":517},"2026-07-01","ACTUAL",{"date":519,"type":517},"2026-01-08",{"date":521,"type":501},"2028-06",{"name":5,"class":6},47]