[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100053932":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":11,"centralContacts":27,"locations":37,"responsibleParty":102,"collaborators":104,"id":108,"slug":109,"hasResults":110,"nctId":111,"briefTitle":112,"officialTitle":113,"acronym":114,"eligibilityCriteria":115,"healthyVolunteers":110,"sex":116,"minAge":117,"maxAge":118,"enrollmentInfo":119,"targetDuration":11,"studyType":122,"phases":123,"briefSummary":126,"conditions":127,"keywords":130,"overallStatus":40,"whyStopped":11,"lastUpdateSubmitDate":132,"lastUpdatePostDateStruct":133,"startDateStruct":136,"completionDateStruct":138,"leadSponsor":140,"locationsCount":141},{"fullName":5,"class":6},"University of South Carolina","OTHER",[8,14,17],{"label":9,"type":10,"description":11,"interventionNames":12},"1 mA A-tDCS","ACTIVE_COMPARATOR",null,[13],"Device: tDCS",{"label":15,"type":10,"description":11,"interventionNames":16},"2 mA A-tDCS",[13],{"label":18,"type":19,"description":11,"interventionNames":20},"S-tDCS","SHAM_COMPARATOR",[13],[22],{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":11},"DEVICE","tDCS","The study intervention will be delivered using the Soterix 1x1 Transcranial Electrical Stimulation Clinical Trials device (Soterix Medical Inc., New York).",[9,15,18],[28,33],{"name":29,"role":30,"phone":31,"phoneExt":11,"email":32},"Leonardo Bonilha","CONTACT","803-216-3469","Leonardo.Bonilha@uscmed.sc.edu",{"name":34,"role":30,"phone":35,"phoneExt":11,"email":36},"Julius Fridriksson","803-777-5931","fridriks@mailbox.sc.edu",[38,63,85],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Medical University of South Carolina","RECRUITING","Charleston","South Carolina","29425","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-79.93275,32.77632,{"lat":50,"lon":49},[53,57,60],{"name":54,"role":30,"phone":55,"phoneExt":11,"email":56},"Kelly Krajeck","843-792-9329","krajeck@musc.edu",{"name":58,"role":59,"phone":11,"phoneExt":11,"email":11},"Janina Wilmskoetter","PRINCIPAL_INVESTIGATOR",{"name":61,"role":62,"phone":11,"phoneExt":11,"email":11},"Christy Cassarly","SUB_INVESTIGATOR",{"facility":5,"status":40,"city":64,"state":42,"zip":65,"country":44,"countryCode":45,"cosmosGeoPoint":66,"geoPoint":70,"contacts":71},"Columbia","29201",{"type":47,"coordinates":67},[68,69],-81.03481,34.00071,{"lat":69,"lon":68},[72,75,76,77,79,81,83],{"name":73,"role":30,"phone":11,"phoneExt":11,"email":74},"Allison Hare","allison.hare@sc.edu",{"name":29,"role":59,"phone":11,"phoneExt":11,"email":11},{"name":34,"role":59,"phone":11,"phoneExt":11,"email":11},{"name":78,"role":62,"phone":11,"phoneExt":11,"email":11},"Chris Rorden",{"name":80,"role":62,"phone":11,"phoneExt":11,"email":11},"Roger Newman-Norlund",{"name":82,"role":62,"phone":11,"phoneExt":11,"email":11},"James Hardin",{"name":84,"role":62,"phone":11,"phoneExt":11,"email":11},"Samaneh Nemati",{"facility":86,"status":40,"city":87,"state":88,"zip":89,"country":44,"countryCode":45,"cosmosGeoPoint":90,"geoPoint":94,"contacts":95},"University of Utah","Salt Lake City","Utah","84112",{"type":47,"coordinates":91},[92,93],-111.89105,40.76078,{"lat":93,"lon":92},[96,99,100],{"name":97,"role":30,"phone":11,"phoneExt":11,"email":98},"Robert Kraemer","Robert.Kraemer@hsc.utah.edu",{"name":97,"role":59,"phone":11,"phoneExt":11,"email":11},{"name":101,"role":62,"phone":11,"phoneExt":11,"email":11},"Julie Wambaugh",{"type":59,"investigatorFullName":29,"investigatorTitle":103,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Primary Investigator",[105],{"name":106,"class":107},"National Institute on Deafness and Other Communication Disorders (NIDCD)","NIH","100053932","phase-2-superiority-trial-of-aphasia-focused-rehabilitation-with-tdcs-stimulation-100053932",false,"NCT07688551","Superiority Trial of Aphasia-focused Rehabilitation With tDCS Stimulation","Transcranial Direct Current Stimulation to Treat Aphasia: A Superiority Study","STARS","Inclusion Criteria:\n\n* Be willing and able to give informed consent.\n* Be willing and able to comply with study requirements.\n* Be between 25 and 80 years of age.\n* Have used English as the primary language for \\> 15 years.\n* Have the diagnosis of aphasia due to a left hemisphere stroke, confirmed by study physician based on past clinical MRI scan or research scan.\n* Be greater than 6 months post-stroke.\n* Have Broca's aphasia diagnosed by the WAB-R (fluency score ≤ 5, auditory verbal comprehension score 4-10, repetition score 0-7.9, naming and word finding score \\\u003C 9).\n* Correctly name 140 or fewer items on the PNT.\n\nExclusion Criteria:\n\n* History of brain surgery except for during the treatment of the acute stroke.\n* Seizures during the previous 12-months.\n* Compromised skin at or near electrode sites (e.g., rash, eczema, wounds, infection).\n* Correctly name more than 140 out of 175 items during the pre-treatment picture naming test (Philadelphia Naming Test).\n* Western Aphasia Battery-Revised Aphasia Quotient (WAB-R AQ) score of 25 or below.\n* Participants with open skull defects (e.g., greater than 1 cm) in the area underneath the anode electrode positioning or participants with metal implants or electrical stimulators.\n* Participants with continuous oxygen therapy which cannot be discontinued for more than 1 hour.\n* Any condition or situation that the PI determines would significantly interfere with the participant's ability to complete the study.","ALL","25 Years","80 Years",{"count":120,"type":121},130,"ESTIMATED","INTERVENTIONAL",[124,125],"PHASE2","PHASE3","The purpose of this study is to help us understand if adding transcranial Direct Current Stimulation (tDCS), a non-invasive brain stimulation technique, to Speech Therapy improves language recovery in people with Broca's aphasia and is more effective than Speech Therapy alone.",[128,129],"Aphasia","Broca's Aphasia",[24,114,128,131],"Stroke","2026-07-10",{"date":134,"type":135},"2026-07-13","ACTUAL",{"date":137,"type":121},"2026-07-31",{"date":139,"type":121},"2030-06",{"name":5,"class":6},3]