[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100572921":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":55,"collaborators":25,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":25,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":25,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":81,"whyStopped":25,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Sheikh Zayed Medical College","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Oral methotrexate group (Group A)","ACTIVE_COMPARATOR","Patients with generalized lichen planus will be given 10 mg per week",[13],"Drug: Methotrexate (drug)",{"label":15,"type":10,"description":16,"interventionNames":17},"Oral Acitretin group (Group B)","Patients with generalized lichen planus will be given oral acitretin 50 mg once daily",[18],"Drug: Acitretin",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Methotrexate (drug)","oral methotrexate 10 mg per week for 12 weeks",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Acitretin","oral acitretin 50 mg once daily for 12 weeks",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Mohibullah, Post graduate resident","CONTACT","+923168716717","mohibzahidi.123@gmail.com",[37],{"facility":38,"status":25,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Sheikh zayed Medical College and Hospital","Rahim Yar Khan","Punjab Province","64200","Pakistan","PK",{"type":45,"coordinates":46},"Point",[47,48],70.30345,28.41987,{"lat":48,"lon":47},[51],{"name":52,"role":33,"phone":53,"phoneExt":25,"email":54},"Sheikh zayed Medical college SZMC\u002FH","+92689230168","info@szmc.edu.pk",{"type":56,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Mohibullah Zahidi","Post Graduate Resident in Dermatology","100572921","phase-2-systemic-treatment-options-for-generalized-lichen-planus-100572921",false,"NCT06739551","Systemic Treatment Options for Generalized Lichen Planus","Comparison of Efficacy of Oral Methotrexate and Acitretin for Generalized Lichen Planus","Inclusion Criteria:\n\n* Age: 18-60 years\n* Gender: both male and female\n* Type of Lichen planus: generalized lichen planus\n* Patients not taking prior treatment in last 1 month\n\nExclusion Criteria:\n\n* Pregnancy and lactating females\n* Bleeding disorders\n* Abnormal liver function tests\n* Platelet count less than 100000\n* Hypersensitivity to Methotrexate or Acitretin\n* Unrealistic expectations","ALL","18 Years","60 Years",{"count":70,"type":71},124,"ESTIMATED","INTERVENTIONAL",[74],"PHASE2","Lichen planus is a chronic inflammatory skin condition with unknown etiology. It requires a long term treatment. Evaulating the most efficacious, safe and affordable treatment option is the need of the hour. This study is going to compare the efficacy of two familiar drugs (acitretin and methotrexate) in the treatment of generalized lichen planus as to find out the relatively more effective and safer treatment.",[77],"Lichen Planus",[77,27,79,80],"Methotrexate","Efficacy","NOT_YET_RECRUITING","2024-12-17",{"date":84,"type":85},"2024-12-18","ACTUAL",{"date":87,"type":71},"2024-12-10",{"date":89,"type":71},"2025-03-20",{"name":5,"class":6},1]