[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100447912":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":108,"centralContacts":113,"locations":114,"responsibleParty":1789,"collaborators":1791,"id":1794,"slug":1795,"hasResults":1796,"nctId":1797,"briefTitle":1798,"officialTitle":1799,"acronym":113,"eligibilityCriteria":1800,"healthyVolunteers":1796,"sex":1801,"minAge":1802,"maxAge":113,"enrollmentInfo":1803,"targetDuration":113,"studyType":1806,"phases":1807,"briefSummary":1809,"conditions":1810,"keywords":113,"overallStatus":117,"whyStopped":113,"lastUpdateSubmitDate":1820,"lastUpdatePostDateStruct":1821,"startDateStruct":1824,"completionDateStruct":1826,"leadSponsor":1828,"locationsCount":1829},{"fullName":5,"class":6},"National Cancer Institute (NCI)","NIH",[8,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Arm I (nivolumab and ipilimumab)","EXPERIMENTAL","Patients receive nivolumab IV over 30 minutes on day 1 of each cycle and ipilimumab IV over 90 minutes on day 1 of every other cycle. Cycles repeat every three weeks. Treatment with nivolumab and ipilimumab repeats for up to 8 cycles in the absence of disease progression, unacceptable toxicity, or CR. Patients then receive nivolumab alone on day 1 of each cycle. Cycles repeat every 4 weeks in the absence of disease progression, unacceptable toxicity, or CR.\n\nMAINTENANCE THERAPY: Patients achieving CR receive nivolumab for an additional 12 months in the absence of disease progression or unacceptable toxicity.\n\nAdditionally, patients may optionally undergo collection of tissue samples on study as well as blood samples throughout the trial. Patients also undergo CT scan and\u002For MRI throughout the trial.",[13,14,15,16,17],"Procedure: Biospecimen Collection","Procedure: Computed Tomography","Biological: Ipilimumab","Procedure: Magnetic Resonance Imaging","Biological: Nivolumab",{"label":19,"type":20,"description":21,"interventionNames":22},"Arm II (nivolumab)","ACTIVE_COMPARATOR","Patients receive nivolumab IV over 30 minutes on day 1 of each cycle. Treatment repeats every 3 weeks for up to 8 cycles, then every 4 weeks thereafter in the absence of disease progression, unacceptable toxicity, or CR.\n\nMAINTENANCE THERAPY: Patients achieving CR receive nivolumab for an additional 12 months in the absence of disease progression or unacceptable toxicity.\n\nAdditionally, patients may optionally undergo collection of tissue samples on study as well as blood samples throughout the trial. Patients also undergo CT scan and\u002For MRI throughout the trial.",[13,14,16,17],[24,34,51,67,87],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":29},"PROCEDURE","Biospecimen Collection","Undergo collection of tissue and\u002For blood samples",[9,19],[30,31,32,33],"Biological Sample Collection","Biospecimen Collected","Sample Collection","Specimen Collection",{"type":25,"name":35,"description":36,"armGroupLabels":37,"otherNames":38},"Computed Tomography","Undergo CT",[9,19],[39,40,41,42,43,44,45,46,47,48,49,50],"CAT","CAT Scan","Computed Axial Tomography","Computerized Axial Tomography","Computerized axial tomography (procedure)","Computerized Tomography","Computerized Tomography (CT) scan","CT","CT Scan","Diagnostic CAT Scan","Diagnostic CAT Scan Service Type","tomography",{"type":52,"name":53,"description":54,"armGroupLabels":55,"otherNames":56},"BIOLOGICAL","Ipilimumab","Given IV",[9],[57,58,59,60,61,62,63,64,65,66],"Anti-Cytotoxic T-Lymphocyte-Associated Antigen-4 Monoclonal Antibody","BMS 734016","BMS-734016","BMS734016","Ipilimumab Biosimilar CS1002","MDX 010","MDX-010","MDX-CTLA4","MDX010","Yervoy",{"type":25,"name":68,"description":69,"armGroupLabels":70,"otherNames":71},"Magnetic Resonance Imaging","Undergo MRI",[9,19],[72,73,74,75,76,77,78,79,80,81,82,83,84,85,86],"Magnetic Resonance","Magnetic Resonance Imaging (MRI)","Magnetic resonance imaging (procedure)","Magnetic Resonance Imaging Scan","Medical Imaging, Magnetic Resonance \u002F Nuclear Magnetic Resonance","MR","MR Imaging","MRI","MRI Scan","MRIs","NMR Imaging","NMRI","Nuclear Magnetic Resonance Imaging","sMRI","Structural MRI",{"type":52,"name":88,"description":54,"armGroupLabels":89,"otherNames":90},"Nivolumab",[9,19],[91,92,93,94,95,96,97,98,99,100,101,102,103,104,105,106,107],"ABP 206","BCD-263","BMS 936558","BMS-936558","BMS936558","CMAB819","MDX 1106","MDX-1106","MDX1106","NIVO","Nivolumab Biosimilar ABP 206","Nivolumab Biosimilar BCD-263","Nivolumab Biosimilar CMAB819","ONO 4538","ONO-4538","ONO4538","Opdivo",[109],{"name":110,"affiliation":111,"role":112},"Haider S Mahdi","NRG Oncology","PRINCIPAL_INVESTIGATOR",null,[115,136,147,156,166,178,187,202,214,226,235,243,255,267,277,292,305,317,329,337,349,365,379,392,405,415,427,438,451,461,473,488,503,514,530,546,558,566,578,586,596,608,620,632,644,656,664,676,688,704,719,731,739,751,763,775,787,799,808,820,832,844,859,874,887,901,912,922,934,946,958,970,985,1000,1016,1027,1041,1055,1068,1083,1096,1109,1125,1140,1152,1167,1179,1191,1200,1215,1227,1239,1251,1263,1279,1293,1303,1317,1326,1342,1354,1366,1380,1392,1405,1416,1429,1442,1454,1466,1478,1490,1497,1510,1522,1535,1545,1555,1564,1574,1584,1597,1609,1622,1637,1653,1663,1675,1689,1704,1718,1724,1738,1750,1759,1768,1781],{"facility":116,"status":117,"city":118,"state":119,"zip":120,"country":121,"countryCode":122,"cosmosGeoPoint":123,"geoPoint":128,"contacts":129},"University of Alabama at Birmingham Cancer Center","RECRUITING","Birmingham","Alabama","35233","United States","US",{"type":124,"coordinates":125},"Point",[126,127],-86.80249,33.52066,{"lat":127,"lon":126},[130,134],{"name":131,"role":132,"phone":113,"phoneExt":113,"email":133},"Site Public Contact","CONTACT","gingerreeves@uabmc.edu",{"name":135,"role":112,"phone":113,"phoneExt":113,"email":113},"Michael D. Toboni",{"facility":137,"status":138,"city":139,"state":140,"zip":141,"country":121,"countryCode":122,"cosmosGeoPoint":142,"geoPoint":146,"contacts":113},"University Cancer and Blood Center LLC","SUSPENDED","Athens","Georgia","30607",{"type":124,"coordinates":143},[144,145],-83.37794,33.96095,{"lat":145,"lon":144},{"facility":148,"status":138,"city":149,"state":140,"zip":150,"country":121,"countryCode":122,"cosmosGeoPoint":151,"geoPoint":155,"contacts":113},"Augusta University Medical Center","Augusta","30912",{"type":124,"coordinates":152},[153,154],-81.97484,33.47097,{"lat":154,"lon":153},{"facility":157,"status":138,"city":158,"state":159,"zip":160,"country":121,"countryCode":122,"cosmosGeoPoint":161,"geoPoint":165,"contacts":113},"Saint Alphonsus Cancer Care Center-Boise","Boise","Idaho","83706",{"type":124,"coordinates":162},[163,164],-116.20345,43.6135,{"lat":164,"lon":163},{"facility":167,"status":117,"city":158,"state":159,"zip":168,"country":121,"countryCode":122,"cosmosGeoPoint":169,"geoPoint":171,"contacts":172},"Saint Luke's Cancer Institute - Boise","83712",{"type":124,"coordinates":170},[163,164],{"lat":164,"lon":163},[173,176],{"name":131,"role":132,"phone":174,"phoneExt":113,"email":175},"208-381-2774","eslinget@slhs.org",{"name":177,"role":112,"phone":113,"phoneExt":113,"email":113},"Dan S. Zuckerman",{"facility":179,"status":138,"city":180,"state":159,"zip":181,"country":121,"countryCode":122,"cosmosGeoPoint":182,"geoPoint":186,"contacts":113},"Saint Alphonsus Cancer Care Center-Caldwell","Caldwell","83605",{"type":124,"coordinates":183},[184,185],-116.68736,43.66294,{"lat":185,"lon":184},{"facility":188,"status":117,"city":189,"state":159,"zip":190,"country":121,"countryCode":122,"cosmosGeoPoint":191,"geoPoint":195,"contacts":196},"Kootenai Health - Coeur d'Alene","Coeur d'Alene","83814",{"type":124,"coordinates":192},[193,194],-116.78047,47.67768,{"lat":194,"lon":193},[197,200],{"name":131,"role":132,"phone":198,"phoneExt":113,"email":199},"406-969-6060","mccinfo@mtcancer.org",{"name":201,"role":112,"phone":113,"phoneExt":113,"email":113},"John M. Schallenkamp",{"facility":203,"status":117,"city":204,"state":159,"zip":205,"country":121,"countryCode":122,"cosmosGeoPoint":206,"geoPoint":210,"contacts":211},"Saint Luke's Cancer Institute - Fruitland","Fruitland","83619",{"type":124,"coordinates":207},[208,209],-116.91655,44.00766,{"lat":209,"lon":208},[212,213],{"name":131,"role":132,"phone":174,"phoneExt":113,"email":175},{"name":177,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":215,"status":117,"city":216,"state":159,"zip":217,"country":121,"countryCode":122,"cosmosGeoPoint":218,"geoPoint":222,"contacts":223},"Saint Luke's Cancer Institute - Meridian","Meridian","83642",{"type":124,"coordinates":219},[220,221],-116.39151,43.61211,{"lat":221,"lon":220},[224,225],{"name":131,"role":132,"phone":174,"phoneExt":113,"email":175},{"name":177,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":227,"status":138,"city":228,"state":159,"zip":229,"country":121,"countryCode":122,"cosmosGeoPoint":230,"geoPoint":234,"contacts":113},"Saint Alphonsus Cancer Care Center-Nampa","Nampa","83687",{"type":124,"coordinates":231},[232,233],-116.56346,43.54072,{"lat":233,"lon":232},{"facility":236,"status":117,"city":228,"state":159,"zip":229,"country":121,"countryCode":122,"cosmosGeoPoint":237,"geoPoint":239,"contacts":240},"Saint Luke's Cancer Institute - Nampa",{"type":124,"coordinates":238},[232,233],{"lat":233,"lon":232},[241,242],{"name":131,"role":132,"phone":174,"phoneExt":113,"email":175},{"name":177,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":244,"status":117,"city":245,"state":159,"zip":246,"country":121,"countryCode":122,"cosmosGeoPoint":247,"geoPoint":251,"contacts":252},"Kootenai Clinic Cancer Services - Post Falls","Post Falls","83854",{"type":124,"coordinates":248},[249,250],-116.95159,47.71796,{"lat":250,"lon":249},[253,254],{"name":131,"role":132,"phone":198,"phoneExt":113,"email":199},{"name":201,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":256,"status":117,"city":257,"state":159,"zip":258,"country":121,"countryCode":122,"cosmosGeoPoint":259,"geoPoint":263,"contacts":264},"Kootenai Clinic Cancer Services - Sandpoint","Sandpoint","83864",{"type":124,"coordinates":260},[261,262],-116.55325,48.27659,{"lat":262,"lon":261},[265,266],{"name":131,"role":132,"phone":198,"phoneExt":113,"email":199},{"name":201,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":268,"status":138,"city":269,"state":270,"zip":271,"country":121,"countryCode":122,"cosmosGeoPoint":272,"geoPoint":276,"contacts":113},"University of Illinois","Chicago","Illinois","60612",{"type":124,"coordinates":273},[274,275],-87.65005,41.85003,{"lat":275,"lon":274},{"facility":278,"status":117,"city":279,"state":270,"zip":280,"country":121,"countryCode":122,"cosmosGeoPoint":281,"geoPoint":285,"contacts":286},"Carle at The Riverfront","Danville","61832",{"type":124,"coordinates":282},[283,284],-87.63002,40.12448,{"lat":284,"lon":283},[287,290],{"name":131,"role":132,"phone":288,"phoneExt":113,"email":289},"800-446-5532","Research@Carle.com",{"name":291,"role":112,"phone":113,"phoneExt":113,"email":113},"Pratima Chalasani",{"facility":293,"status":117,"city":294,"state":270,"zip":295,"country":121,"countryCode":122,"cosmosGeoPoint":296,"geoPoint":300,"contacts":301},"Carle Physician Group-Effingham","Effingham","62401",{"type":124,"coordinates":297},[298,299],-88.54338,39.12004,{"lat":299,"lon":298},[302,304],{"name":131,"role":132,"phone":288,"phoneExt":113,"email":303},"Research@carle.com",{"name":291,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":306,"status":117,"city":307,"state":270,"zip":308,"country":121,"countryCode":122,"cosmosGeoPoint":309,"geoPoint":313,"contacts":314},"Carle Physician Group-Mattoon\u002FCharleston","Mattoon","61938",{"type":124,"coordinates":310},[311,312],-88.37283,39.48309,{"lat":312,"lon":311},[315,316],{"name":131,"role":132,"phone":288,"phoneExt":113,"email":303},{"name":291,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":318,"status":117,"city":319,"state":270,"zip":320,"country":121,"countryCode":122,"cosmosGeoPoint":321,"geoPoint":325,"contacts":326},"Carle BroMenn Medical Center","Normal","61761",{"type":124,"coordinates":322},[323,324],-88.99063,40.5142,{"lat":324,"lon":323},[327,328],{"name":131,"role":132,"phone":288,"phoneExt":113,"email":289},{"name":291,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":330,"status":117,"city":319,"state":270,"zip":320,"country":121,"countryCode":122,"cosmosGeoPoint":331,"geoPoint":333,"contacts":334},"Carle Cancer Institute Normal",{"type":124,"coordinates":332},[323,324],{"lat":324,"lon":323},[335,336],{"name":131,"role":132,"phone":288,"phoneExt":113,"email":289},{"name":291,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":338,"status":117,"city":339,"state":270,"zip":340,"country":121,"countryCode":122,"cosmosGeoPoint":341,"geoPoint":345,"contacts":346},"Carle Cancer Center","Urbana","61801",{"type":124,"coordinates":342},[343,344],-88.20727,40.11059,{"lat":344,"lon":343},[347,348],{"name":131,"role":132,"phone":288,"phoneExt":113,"email":303},{"name":291,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":350,"status":117,"city":351,"state":352,"zip":353,"country":121,"countryCode":122,"cosmosGeoPoint":354,"geoPoint":358,"contacts":359},"IU Health North Hospital","Carmel","Indiana","46032",{"type":124,"coordinates":355},[356,357],-86.11804,39.97837,{"lat":357,"lon":356},[360,363],{"name":131,"role":132,"phone":361,"phoneExt":113,"email":362},"317-278-5632","iutrials@iu.edu",{"name":364,"role":112,"phone":113,"phoneExt":113,"email":113},"Jessica E. Parker",{"facility":366,"status":117,"city":367,"state":352,"zip":368,"country":121,"countryCode":122,"cosmosGeoPoint":369,"geoPoint":373,"contacts":374},"Northwest Cancer Center - Crown Point","Crown Point","46307",{"type":124,"coordinates":370},[371,372],-87.36531,41.41698,{"lat":372,"lon":371},[375,378],{"name":131,"role":132,"phone":376,"phoneExt":113,"email":377},"219-836-6879","CancerResearch@powershealth.org",{"name":291,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":380,"status":117,"city":381,"state":352,"zip":382,"country":121,"countryCode":122,"cosmosGeoPoint":383,"geoPoint":387,"contacts":388},"Northwest Oncology LLC","Dyer","46311",{"type":124,"coordinates":384},[385,386],-87.52171,41.4942,{"lat":386,"lon":385},[389,391],{"name":131,"role":132,"phone":390,"phoneExt":113,"email":113},"219-924-8178",{"name":291,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":393,"status":117,"city":394,"state":352,"zip":395,"country":121,"countryCode":122,"cosmosGeoPoint":396,"geoPoint":400,"contacts":401},"Northwest Cancer Center - Hobart","Hobart","46342",{"type":124,"coordinates":397},[398,399],-87.25504,41.53226,{"lat":399,"lon":398},[402,404],{"name":131,"role":132,"phone":403,"phoneExt":113,"email":113},"219-947-1795",{"name":291,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":406,"status":117,"city":394,"state":352,"zip":395,"country":121,"countryCode":122,"cosmosGeoPoint":407,"geoPoint":409,"contacts":410},"Saint Mary Medical Center",{"type":124,"coordinates":408},[398,399],{"lat":399,"lon":398},[411,414],{"name":131,"role":132,"phone":412,"phoneExt":113,"email":413},"219-836-6875","CancerResearch@COMHS.org",{"name":291,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":416,"status":117,"city":417,"state":352,"zip":418,"country":121,"countryCode":122,"cosmosGeoPoint":419,"geoPoint":423,"contacts":424},"Indiana University\u002FMelvin and Bren Simon Cancer Center","Indianapolis","46202",{"type":124,"coordinates":420},[421,422],-86.15804,39.76838,{"lat":422,"lon":421},[425,426],{"name":131,"role":132,"phone":361,"phoneExt":113,"email":362},{"name":364,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":428,"status":117,"city":417,"state":352,"zip":429,"country":121,"countryCode":122,"cosmosGeoPoint":430,"geoPoint":432,"contacts":433},"Saint Catherine Hospital","46312",{"type":124,"coordinates":431},[421,422],{"lat":422,"lon":421},[434,437],{"name":131,"role":132,"phone":435,"phoneExt":113,"email":436},"412-339-5294","Roster@nrgoncology.org",{"name":291,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":439,"status":117,"city":440,"state":352,"zip":441,"country":121,"countryCode":122,"cosmosGeoPoint":442,"geoPoint":446,"contacts":447},"The Community Hospital","Munster","46321",{"type":124,"coordinates":443},[444,445],-87.51254,41.56448,{"lat":445,"lon":444},[448,450],{"name":131,"role":132,"phone":449,"phoneExt":113,"email":113},"219-836-3349",{"name":291,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":452,"status":117,"city":440,"state":352,"zip":441,"country":121,"countryCode":122,"cosmosGeoPoint":453,"geoPoint":455,"contacts":456},"Women's Diagnostic Center - Munster",{"type":124,"coordinates":454},[444,445],{"lat":445,"lon":444},[457,460],{"name":131,"role":132,"phone":458,"phoneExt":113,"email":459},"219-934-8869","mnicholson@comhs.org",{"name":291,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":462,"status":117,"city":463,"state":352,"zip":464,"country":121,"countryCode":122,"cosmosGeoPoint":465,"geoPoint":469,"contacts":470},"Northwest Cancer Center - Valparaiso","Valparaiso","46383",{"type":124,"coordinates":466},[467,468],-87.06114,41.47309,{"lat":468,"lon":467},[471,472],{"name":131,"role":132,"phone":412,"phoneExt":113,"email":413},{"name":291,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":474,"status":117,"city":475,"state":476,"zip":477,"country":121,"countryCode":122,"cosmosGeoPoint":478,"geoPoint":482,"contacts":483},"University of Iowa\u002FHolden Comprehensive Cancer Center","Iowa City","Iowa","52242",{"type":124,"coordinates":479},[480,481],-91.53017,41.66113,{"lat":481,"lon":480},[484,486],{"name":131,"role":132,"phone":485,"phoneExt":113,"email":113},"800-237-1225",{"name":487,"role":112,"phone":113,"phoneExt":113,"email":113},"David P. Bender",{"facility":489,"status":117,"city":490,"state":491,"zip":492,"country":121,"countryCode":122,"cosmosGeoPoint":493,"geoPoint":497,"contacts":498},"The James Graham Brown Cancer Center at University of Louisville","Louisville","Kentucky","40202",{"type":124,"coordinates":494},[495,496],-85.75941,38.25424,{"lat":496,"lon":495},[499,501],{"name":131,"role":132,"phone":500,"phoneExt":113,"email":113},"502-562-3429",{"name":502,"role":112,"phone":113,"phoneExt":113,"email":113},"Jason A. Chesney",{"facility":504,"status":117,"city":490,"state":491,"zip":505,"country":121,"countryCode":122,"cosmosGeoPoint":506,"geoPoint":508,"contacts":509},"UofL Health Medical Center Northeast","40245",{"type":124,"coordinates":507},[495,496],{"lat":496,"lon":495},[510,513],{"name":131,"role":132,"phone":511,"phoneExt":113,"email":512},"502-852-2755","ctoinfo@louisville.edu",{"name":502,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":515,"status":117,"city":516,"state":517,"zip":518,"country":121,"countryCode":122,"cosmosGeoPoint":519,"geoPoint":523,"contacts":524},"MaineHealth Maine Medical Center- Scarborough","Scarborough","Maine","04074",{"type":124,"coordinates":520},[521,522],-70.32172,43.57814,{"lat":522,"lon":521},[525,528],{"name":131,"role":132,"phone":526,"phoneExt":113,"email":527},"207-396-8670","clinicalresearch@mainehealth.org",{"name":529,"role":112,"phone":113,"phoneExt":113,"email":113},"Leslie S. Bradford",{"facility":531,"status":117,"city":532,"state":533,"zip":534,"country":121,"countryCode":122,"cosmosGeoPoint":535,"geoPoint":539,"contacts":540},"Bronson Battle Creek","Battle Creek","Michigan","49017",{"type":124,"coordinates":536},[537,538],-85.17816,42.3173,{"lat":538,"lon":537},[541,544],{"name":131,"role":132,"phone":542,"phoneExt":113,"email":543},"616-391-1230","crcwm-regulatory@crcwm.org",{"name":545,"role":112,"phone":113,"phoneExt":113,"email":113},"Kathleen Y. Butler",{"facility":547,"status":117,"city":548,"state":533,"zip":549,"country":121,"countryCode":122,"cosmosGeoPoint":550,"geoPoint":554,"contacts":555},"Corewell Health Grand Rapids Hospitals - Butterworth Hospital","Grand Rapids","49503",{"type":124,"coordinates":551},[552,553],-85.66809,42.96336,{"lat":553,"lon":552},[556,557],{"name":131,"role":132,"phone":542,"phoneExt":113,"email":543},{"name":545,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":559,"status":117,"city":548,"state":533,"zip":549,"country":121,"countryCode":122,"cosmosGeoPoint":560,"geoPoint":562,"contacts":563},"Trinity Health Grand Rapids Hospital",{"type":124,"coordinates":561},[552,553],{"lat":553,"lon":552},[564,565],{"name":131,"role":132,"phone":542,"phoneExt":113,"email":543},{"name":545,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":567,"status":117,"city":568,"state":533,"zip":569,"country":121,"countryCode":122,"cosmosGeoPoint":570,"geoPoint":574,"contacts":575},"Bronson Methodist Hospital","Kalamazoo","49007",{"type":124,"coordinates":571},[572,573],-85.58723,42.29171,{"lat":573,"lon":572},[576,577],{"name":131,"role":132,"phone":542,"phoneExt":113,"email":543},{"name":545,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":579,"status":117,"city":568,"state":533,"zip":569,"country":121,"countryCode":122,"cosmosGeoPoint":580,"geoPoint":582,"contacts":583},"West Michigan Cancer Center",{"type":124,"coordinates":581},[572,573],{"lat":573,"lon":572},[584,585],{"name":131,"role":132,"phone":542,"phoneExt":113,"email":543},{"name":545,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":587,"status":117,"city":568,"state":533,"zip":588,"country":121,"countryCode":122,"cosmosGeoPoint":589,"geoPoint":591,"contacts":592},"Beacon Kalamazoo Cancer Center","49009",{"type":124,"coordinates":590},[572,573],{"lat":573,"lon":572},[593,595],{"name":131,"role":132,"phone":594,"phoneExt":113,"email":113},"574-647-7370",{"name":545,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":597,"status":117,"city":598,"state":533,"zip":599,"country":121,"countryCode":122,"cosmosGeoPoint":600,"geoPoint":604,"contacts":605},"Trinity Health Muskegon Hospital","Muskegon","49444",{"type":124,"coordinates":601},[602,603],-86.24839,43.23418,{"lat":603,"lon":602},[606,607],{"name":131,"role":132,"phone":542,"phoneExt":113,"email":543},{"name":545,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":609,"status":117,"city":610,"state":533,"zip":611,"country":121,"countryCode":122,"cosmosGeoPoint":612,"geoPoint":616,"contacts":617},"Corewell Health Lakeland Hospitals - Niles Hospital","Niles","49120",{"type":124,"coordinates":613},[614,615],-86.25418,41.82977,{"lat":615,"lon":614},[618,619],{"name":131,"role":132,"phone":542,"phoneExt":113,"email":113},{"name":545,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":621,"status":117,"city":622,"state":533,"zip":599,"country":121,"countryCode":122,"cosmosGeoPoint":623,"geoPoint":627,"contacts":628},"Cancer and Hematology Centers of Western Michigan - Norton Shores","Norton Shores",{"type":124,"coordinates":624},[625,626],-86.26395,43.1689,{"lat":626,"lon":625},[629,631],{"name":131,"role":132,"phone":542,"phoneExt":113,"email":630},"connie.szczepanek@crcwm.org",{"name":545,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":633,"status":117,"city":634,"state":533,"zip":635,"country":121,"countryCode":122,"cosmosGeoPoint":636,"geoPoint":640,"contacts":641},"Corewell Health Reed City Hospital","Reed City","49677",{"type":124,"coordinates":637},[638,639],-85.51005,43.87502,{"lat":639,"lon":638},[642,643],{"name":131,"role":132,"phone":542,"phoneExt":113,"email":543},{"name":545,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":645,"status":117,"city":646,"state":533,"zip":647,"country":121,"countryCode":122,"cosmosGeoPoint":648,"geoPoint":652,"contacts":653},"Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center","Saint Joseph","49085",{"type":124,"coordinates":649},[650,651],-86.48002,42.10976,{"lat":651,"lon":650},[654,655],{"name":131,"role":132,"phone":542,"phoneExt":113,"email":543},{"name":545,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":657,"status":117,"city":646,"state":533,"zip":647,"country":121,"countryCode":122,"cosmosGeoPoint":658,"geoPoint":660,"contacts":661},"Corewell Health Lakeland Hospitals - Saint Joseph Hospital",{"type":124,"coordinates":659},[650,651],{"lat":651,"lon":650},[662,663],{"name":131,"role":132,"phone":542,"phoneExt":113,"email":543},{"name":545,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":665,"status":117,"city":666,"state":533,"zip":667,"country":121,"countryCode":122,"cosmosGeoPoint":668,"geoPoint":672,"contacts":673},"Munson Medical Center","Traverse City","49684",{"type":124,"coordinates":669},[670,671],-85.62063,44.76306,{"lat":671,"lon":670},[674,675],{"name":131,"role":132,"phone":542,"phoneExt":113,"email":543},{"name":545,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":677,"status":117,"city":678,"state":533,"zip":679,"country":121,"countryCode":122,"cosmosGeoPoint":680,"geoPoint":684,"contacts":685},"University of Michigan Health - West","Wyoming","49519",{"type":124,"coordinates":681},[682,683],-85.70531,42.91336,{"lat":683,"lon":682},[686,687],{"name":131,"role":132,"phone":542,"phoneExt":113,"email":543},{"name":545,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":689,"status":117,"city":690,"state":691,"zip":692,"country":121,"countryCode":122,"cosmosGeoPoint":693,"geoPoint":697,"contacts":698},"Mercy Hospital","Coon Rapids","Minnesota","55433",{"type":124,"coordinates":694},[695,696],-93.28773,45.11997,{"lat":696,"lon":695},[699,702],{"name":131,"role":132,"phone":700,"phoneExt":113,"email":701},"952-993-1517","mmcorc@healthpartners.com",{"name":703,"role":112,"phone":113,"phoneExt":113,"email":113},"Adrianne Mallen",{"facility":705,"status":117,"city":706,"state":691,"zip":707,"country":121,"countryCode":122,"cosmosGeoPoint":708,"geoPoint":712,"contacts":713},"Essentia Health - Deer River Clinic","Deer River","56636",{"type":124,"coordinates":709},[710,711],-93.79272,47.333,{"lat":711,"lon":710},[714,717],{"name":131,"role":132,"phone":715,"phoneExt":113,"email":716},"218-786-3308","CancerTrials@EssentiaHealth.org",{"name":718,"role":112,"phone":113,"phoneExt":113,"email":113},"Bret E. Friday",{"facility":720,"status":117,"city":721,"state":691,"zip":722,"country":121,"countryCode":122,"cosmosGeoPoint":723,"geoPoint":727,"contacts":728},"Essentia Health Cancer Center","Duluth","55805",{"type":124,"coordinates":724},[725,726],-92.10658,46.78327,{"lat":726,"lon":725},[729,730],{"name":131,"role":132,"phone":715,"phoneExt":113,"email":716},{"name":718,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":732,"status":117,"city":721,"state":691,"zip":722,"country":121,"countryCode":122,"cosmosGeoPoint":733,"geoPoint":735,"contacts":736},"Miller-Dwan Hospital",{"type":124,"coordinates":734},[725,726],{"lat":726,"lon":725},[737,738],{"name":131,"role":132,"phone":715,"phoneExt":113,"email":716},{"name":718,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":740,"status":117,"city":741,"state":691,"zip":742,"country":121,"countryCode":122,"cosmosGeoPoint":743,"geoPoint":747,"contacts":748},"Fairview Southdale Hospital","Edina","55435",{"type":124,"coordinates":744},[745,746],-93.34995,44.88969,{"lat":746,"lon":745},[749,750],{"name":131,"role":132,"phone":700,"phoneExt":113,"email":701},{"name":703,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":752,"status":117,"city":753,"state":691,"zip":754,"country":121,"countryCode":122,"cosmosGeoPoint":755,"geoPoint":759,"contacts":760},"Essentia Health Hibbing Clinic","Hibbing","55746",{"type":124,"coordinates":756},[757,758],-92.93769,47.42715,{"lat":758,"lon":757},[761,762],{"name":131,"role":132,"phone":715,"phoneExt":113,"email":113},{"name":718,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":764,"status":117,"city":765,"state":691,"zip":766,"country":121,"countryCode":122,"cosmosGeoPoint":767,"geoPoint":771,"contacts":772},"Abbott-Northwestern Hospital","Minneapolis","55407",{"type":124,"coordinates":768},[769,770],-93.26384,44.97997,{"lat":770,"lon":769},[773,774],{"name":131,"role":132,"phone":700,"phoneExt":113,"email":701},{"name":703,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":776,"status":117,"city":777,"state":691,"zip":778,"country":121,"countryCode":122,"cosmosGeoPoint":779,"geoPoint":783,"contacts":784},"Park Nicollet Clinic - Saint Louis Park","Saint Louis Park","55416",{"type":124,"coordinates":780},[781,782],-93.34801,44.9483,{"lat":782,"lon":781},[785,786],{"name":131,"role":132,"phone":700,"phoneExt":113,"email":701},{"name":703,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":788,"status":117,"city":789,"state":691,"zip":790,"country":121,"countryCode":122,"cosmosGeoPoint":791,"geoPoint":795,"contacts":796},"Regions Hospital","Saint Paul","55101",{"type":124,"coordinates":792},[793,794],-93.09327,44.94441,{"lat":794,"lon":793},[797,798],{"name":131,"role":132,"phone":700,"phoneExt":113,"email":701},{"name":703,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":800,"status":117,"city":789,"state":691,"zip":801,"country":121,"countryCode":122,"cosmosGeoPoint":802,"geoPoint":804,"contacts":805},"United Hospital","55102",{"type":124,"coordinates":803},[793,794],{"lat":794,"lon":793},[806,807],{"name":131,"role":132,"phone":700,"phoneExt":113,"email":701},{"name":703,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":809,"status":117,"city":810,"state":691,"zip":811,"country":121,"countryCode":122,"cosmosGeoPoint":812,"geoPoint":816,"contacts":817},"Essentia Health Sandstone","Sandstone","55072",{"type":124,"coordinates":813},[814,815],-92.86742,46.13106,{"lat":815,"lon":814},[818,819],{"name":131,"role":132,"phone":715,"phoneExt":113,"email":716},{"name":718,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":821,"status":117,"city":822,"state":691,"zip":823,"country":121,"countryCode":122,"cosmosGeoPoint":824,"geoPoint":828,"contacts":829},"Saint Francis Regional Medical Center","Shakopee","55379",{"type":124,"coordinates":825},[826,827],-93.5269,44.79802,{"lat":827,"lon":826},[830,831],{"name":131,"role":132,"phone":700,"phoneExt":113,"email":701},{"name":703,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":833,"status":117,"city":834,"state":691,"zip":835,"country":121,"countryCode":122,"cosmosGeoPoint":836,"geoPoint":840,"contacts":841},"Essentia Health Virginia Clinic","Virginia","55792",{"type":124,"coordinates":837},[838,839],-92.53657,47.52326,{"lat":839,"lon":838},[842,843],{"name":131,"role":132,"phone":715,"phoneExt":113,"email":716},{"name":718,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":845,"status":117,"city":846,"state":847,"zip":848,"country":121,"countryCode":122,"cosmosGeoPoint":849,"geoPoint":853,"contacts":854},"MU Health - University Hospital\u002FEllis Fischel Cancer Center","Columbia","Missouri","65212",{"type":124,"coordinates":850},[851,852],-92.33407,38.95171,{"lat":852,"lon":851},[855,857],{"name":131,"role":132,"phone":856,"phoneExt":113,"email":113},"573-882-7440",{"name":858,"role":112,"phone":113,"phoneExt":113,"email":113},"Arwa M. Mohammad",{"facility":860,"status":117,"city":861,"state":847,"zip":862,"country":121,"countryCode":122,"cosmosGeoPoint":863,"geoPoint":867,"contacts":868},"Washington University School of Medicine","St Louis","63110",{"type":124,"coordinates":864},[865,866],-90.19789,38.62727,{"lat":866,"lon":865},[869,872],{"name":131,"role":132,"phone":870,"phoneExt":113,"email":871},"800-600-3606","info@siteman.wustl.edu",{"name":873,"role":112,"phone":113,"phoneExt":113,"email":113},"Premal H. Thaker",{"facility":875,"status":117,"city":876,"state":877,"zip":878,"country":121,"countryCode":122,"cosmosGeoPoint":879,"geoPoint":883,"contacts":884},"Community Hospital of Anaconda","Anaconda","Montana","59711",{"type":124,"coordinates":880},[881,882],-112.94226,46.12854,{"lat":882,"lon":881},[885,886],{"name":131,"role":132,"phone":198,"phoneExt":113,"email":199},{"name":201,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":888,"status":117,"city":889,"state":877,"zip":890,"country":121,"countryCode":122,"cosmosGeoPoint":891,"geoPoint":895,"contacts":896},"Billings Clinic Cancer Center","Billings","59101",{"type":124,"coordinates":892},[893,894],-108.50069,45.78329,{"lat":894,"lon":893},[897,900],{"name":131,"role":132,"phone":898,"phoneExt":113,"email":899},"800-996-2663","research@billingsclinic.org",{"name":201,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":902,"status":117,"city":889,"state":877,"zip":903,"country":121,"countryCode":122,"cosmosGeoPoint":904,"geoPoint":906,"contacts":907},"Saint Vincent Frontier Cancer Center","59102",{"type":124,"coordinates":905},[893,894],{"lat":894,"lon":893},[908,910],{"name":131,"role":132,"phone":909,"phoneExt":113,"email":113},"800-648-6274",{"name":911,"role":112,"phone":113,"phoneExt":113,"email":113},"Megan Petersen",{"facility":913,"status":117,"city":889,"state":877,"zip":914,"country":121,"countryCode":122,"cosmosGeoPoint":915,"geoPoint":917,"contacts":918},"Intermountain Health West End Clinic","59106",{"type":124,"coordinates":916},[893,894],{"lat":894,"lon":893},[919,921],{"name":131,"role":132,"phone":920,"phoneExt":113,"email":113},"406-238-6685",{"name":911,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":923,"status":117,"city":924,"state":877,"zip":925,"country":121,"countryCode":122,"cosmosGeoPoint":926,"geoPoint":930,"contacts":931},"Bozeman Health Deaconess Hospital","Bozeman","59715",{"type":124,"coordinates":927},[928,929],-111.03856,45.67965,{"lat":929,"lon":928},[932,933],{"name":131,"role":132,"phone":198,"phoneExt":113,"email":199},{"name":201,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":935,"status":117,"city":936,"state":877,"zip":937,"country":121,"countryCode":122,"cosmosGeoPoint":938,"geoPoint":942,"contacts":943},"Benefis Sletten Cancer Institute","Great Falls","59405",{"type":124,"coordinates":939},[940,941],-111.30081,47.50024,{"lat":941,"lon":940},[944,945],{"name":131,"role":132,"phone":198,"phoneExt":113,"email":199},{"name":201,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":947,"status":117,"city":948,"state":877,"zip":949,"country":121,"countryCode":122,"cosmosGeoPoint":950,"geoPoint":954,"contacts":955},"Logan Health Medical Center","Kalispell","59901",{"type":124,"coordinates":951},[952,953],-114.31291,48.19579,{"lat":953,"lon":952},[956,957],{"name":131,"role":132,"phone":198,"phoneExt":113,"email":199},{"name":201,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":959,"status":117,"city":960,"state":877,"zip":961,"country":121,"countryCode":122,"cosmosGeoPoint":962,"geoPoint":966,"contacts":967},"Community Medical Center","Missoula","59804",{"type":124,"coordinates":963},[964,965],-113.994,46.87215,{"lat":965,"lon":964},[968,969],{"name":131,"role":132,"phone":198,"phoneExt":113,"email":199},{"name":201,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":971,"status":117,"city":972,"state":973,"zip":974,"country":121,"countryCode":122,"cosmosGeoPoint":975,"geoPoint":979,"contacts":980},"Nebraska Methodist Hospital","Omaha","Nebraska","68114",{"type":124,"coordinates":976},[977,978],-95.94043,41.25626,{"lat":978,"lon":977},[981,983],{"name":131,"role":132,"phone":982,"phoneExt":113,"email":113},"402-354-5144",{"name":984,"role":112,"phone":113,"phoneExt":113,"email":113},"Brent J. Tierney",{"facility":986,"status":117,"city":987,"state":988,"zip":989,"country":121,"countryCode":122,"cosmosGeoPoint":990,"geoPoint":994,"contacts":995},"Women's Cancer Center of Nevada","Las Vegas","Nevada","89106",{"type":124,"coordinates":991},[992,993],-115.13722,36.17497,{"lat":993,"lon":992},[996,998],{"name":131,"role":132,"phone":997,"phoneExt":113,"email":113},"702-851-4672",{"name":999,"role":112,"phone":113,"phoneExt":113,"email":113},"Nicola M. Spirtos",{"facility":1001,"status":117,"city":1002,"state":1003,"zip":1004,"country":121,"countryCode":122,"cosmosGeoPoint":1005,"geoPoint":1009,"contacts":1010},"University of New Mexico Cancer Center","Albuquerque","New Mexico","87106",{"type":124,"coordinates":1006},[1007,1008],-106.65114,35.08449,{"lat":1008,"lon":1007},[1011,1014],{"name":131,"role":132,"phone":1012,"phoneExt":113,"email":1013},"505-925-0348","HSC-ClinicalTrialInfo@salud.unm.edu",{"name":1015,"role":112,"phone":113,"phoneExt":113,"email":113},"Carolyn Y. Muller",{"facility":1017,"status":1018,"city":1019,"state":1020,"zip":1021,"country":121,"countryCode":122,"cosmosGeoPoint":1022,"geoPoint":1026,"contacts":113},"Roswell Park Cancer Institute","ACTIVE_NOT_RECRUITING","Buffalo","New York","14263",{"type":124,"coordinates":1023},[1024,1025],-78.87837,42.88645,{"lat":1025,"lon":1024},{"facility":1028,"status":117,"city":1029,"state":1020,"zip":1030,"country":121,"countryCode":122,"cosmosGeoPoint":1031,"geoPoint":1035,"contacts":1036},"University of Rochester","Rochester","14642",{"type":124,"coordinates":1032},[1033,1034],-77.61556,43.15478,{"lat":1034,"lon":1033},[1037,1039],{"name":131,"role":132,"phone":1038,"phoneExt":113,"email":113},"585-275-5830",{"name":1040,"role":112,"phone":113,"phoneExt":113,"email":113},"Rachael Turner",{"facility":1042,"status":117,"city":1043,"state":1020,"zip":1044,"country":121,"countryCode":122,"cosmosGeoPoint":1045,"geoPoint":1049,"contacts":1050},"State University of New York Upstate Medical University","Syracuse","13210",{"type":124,"coordinates":1046},[1047,1048],-76.14742,43.04812,{"lat":1048,"lon":1047},[1051,1053],{"name":131,"role":132,"phone":1052,"phoneExt":113,"email":113},"315-464-5476",{"name":1054,"role":112,"phone":113,"phoneExt":113,"email":113},"Mary J. Cunningham",{"facility":1056,"status":117,"city":1057,"state":1020,"zip":1058,"country":121,"countryCode":122,"cosmosGeoPoint":1059,"geoPoint":1063,"contacts":1064},"Wilmot Cancer Institute at Webster","Webster","14580",{"type":124,"coordinates":1060},[1061,1062],-77.42999,43.21229,{"lat":1062,"lon":1061},[1065,1067],{"name":131,"role":132,"phone":113,"phoneExt":113,"email":1066},"WCICTOresearch@urmc.rochester.edu",{"name":1040,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1069,"status":117,"city":1070,"state":1071,"zip":1072,"country":121,"countryCode":122,"cosmosGeoPoint":1073,"geoPoint":1077,"contacts":1078},"Duke University Medical Center","Durham","North Carolina","27710",{"type":124,"coordinates":1074},[1075,1076],-78.89862,35.99403,{"lat":1076,"lon":1075},[1079,1081],{"name":131,"role":132,"phone":1080,"phoneExt":113,"email":113},"888-275-3853",{"name":1082,"role":112,"phone":113,"phoneExt":113,"email":113},"Angeles A. Secord",{"facility":1084,"status":117,"city":1085,"state":1071,"zip":1086,"country":121,"countryCode":122,"cosmosGeoPoint":1087,"geoPoint":1091,"contacts":1092},"Duke Women's Cancer Care Raleigh","Raleigh","27607",{"type":124,"coordinates":1088},[1089,1090],-78.63861,35.7721,{"lat":1090,"lon":1089},[1093,1095],{"name":131,"role":132,"phone":1094,"phoneExt":113,"email":113},"919-785-4878",{"name":1082,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1097,"status":117,"city":1098,"state":1099,"zip":1100,"country":121,"countryCode":122,"cosmosGeoPoint":1101,"geoPoint":1105,"contacts":1106},"Essentia Health Cancer Center-South University Clinic","Fargo","North Dakota","58103",{"type":124,"coordinates":1102},[1103,1104],-96.7898,46.87719,{"lat":1104,"lon":1103},[1107,1108],{"name":131,"role":132,"phone":715,"phoneExt":113,"email":716},{"name":718,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1110,"status":117,"city":1111,"state":1112,"zip":1113,"country":121,"countryCode":122,"cosmosGeoPoint":1114,"geoPoint":1118,"contacts":1119},"UHHS-Chagrin Highlands Medical Center","Beachwood","Ohio","44122",{"type":124,"coordinates":1115},[1116,1117],-81.50873,41.4645,{"lat":1117,"lon":1116},[1120,1123],{"name":131,"role":132,"phone":1121,"phoneExt":113,"email":1122},"800-641-2422","CTUReferral@UHhospitals.org",{"name":1124,"role":112,"phone":113,"phoneExt":113,"email":113},"Amy Armstrong",{"facility":1126,"status":117,"city":1127,"state":1112,"zip":1128,"country":121,"countryCode":122,"cosmosGeoPoint":1129,"geoPoint":1133,"contacts":1134},"Miami Valley Hospital South","Centerville","45459",{"type":124,"coordinates":1130},[1131,1132],-84.15938,39.62839,{"lat":1132,"lon":1131},[1135,1138],{"name":131,"role":132,"phone":1136,"phoneExt":113,"email":1137},"937-528-2900","clinical.trials@daytonncorp.org",{"name":1139,"role":112,"phone":113,"phoneExt":113,"email":113},"Michael S. Guy",{"facility":1141,"status":117,"city":1142,"state":1112,"zip":1143,"country":121,"countryCode":122,"cosmosGeoPoint":1144,"geoPoint":1148,"contacts":1149},"Geauga Hospital","Chardon","44024",{"type":124,"coordinates":1145},[1146,1147],-81.14899,41.61422,{"lat":1147,"lon":1146},[1150,1151],{"name":131,"role":132,"phone":1121,"phoneExt":113,"email":1122},{"name":1124,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1153,"status":117,"city":1154,"state":1112,"zip":1155,"country":121,"countryCode":122,"cosmosGeoPoint":1156,"geoPoint":1160,"contacts":1161},"Good Samaritan Hospital - Cincinnati","Cincinnati","45220",{"type":124,"coordinates":1157},[1158,1159],-84.51439,39.12711,{"lat":1159,"lon":1158},[1162,1165],{"name":131,"role":132,"phone":1163,"phoneExt":113,"email":1164},"720-874-1881","ResearchInstituteInquiries@CommonSpirit.org",{"name":1166,"role":112,"phone":113,"phoneExt":113,"email":113},"Shahzad Siddique",{"facility":1168,"status":117,"city":1169,"state":1112,"zip":1170,"country":121,"countryCode":122,"cosmosGeoPoint":1171,"geoPoint":1175,"contacts":1176},"Case Western Reserve University","Cleveland","44106",{"type":124,"coordinates":1172},[1173,1174],-81.69541,41.4995,{"lat":1174,"lon":1173},[1177,1178],{"name":131,"role":132,"phone":1121,"phoneExt":113,"email":1122},{"name":1124,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1180,"status":117,"city":1169,"state":1112,"zip":1181,"country":121,"countryCode":122,"cosmosGeoPoint":1182,"geoPoint":1184,"contacts":1185},"Cleveland Clinic Cancer Center\u002FFairview Hospital","44111",{"type":124,"coordinates":1183},[1173,1174],{"lat":1174,"lon":1173},[1186,1189],{"name":131,"role":132,"phone":1187,"phoneExt":113,"email":1188},"866-223-8100","TaussigResearch@ccf.org",{"name":1190,"role":112,"phone":113,"phoneExt":113,"email":113},"Peter G. Rose",{"facility":1192,"status":117,"city":1169,"state":1112,"zip":1193,"country":121,"countryCode":122,"cosmosGeoPoint":1194,"geoPoint":1196,"contacts":1197},"Cleveland Clinic Foundation","44195",{"type":124,"coordinates":1195},[1173,1174],{"lat":1174,"lon":1173},[1198,1199],{"name":131,"role":132,"phone":1187,"phoneExt":113,"email":1188},{"name":1190,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1201,"status":117,"city":1202,"state":1112,"zip":1203,"country":121,"countryCode":122,"cosmosGeoPoint":1204,"geoPoint":1208,"contacts":1209},"Ohio State University Comprehensive Cancer Center","Columbus","43210",{"type":124,"coordinates":1205},[1206,1207],-82.99879,39.96118,{"lat":1207,"lon":1206},[1210,1213],{"name":131,"role":132,"phone":1211,"phoneExt":113,"email":1212},"800-293-5066","Jamesline@osumc.edu",{"name":1214,"role":112,"phone":113,"phoneExt":113,"email":113},"Floor Backes",{"facility":1216,"status":117,"city":1217,"state":1112,"zip":1218,"country":121,"countryCode":122,"cosmosGeoPoint":1219,"geoPoint":1223,"contacts":1224},"Hillcrest Hospital Cancer Center","Mayfield Heights","44124",{"type":124,"coordinates":1220},[1221,1222],-81.4579,41.51922,{"lat":1222,"lon":1221},[1225,1226],{"name":131,"role":132,"phone":1187,"phoneExt":113,"email":1188},{"name":1190,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1228,"status":117,"city":1229,"state":1112,"zip":1230,"country":121,"countryCode":122,"cosmosGeoPoint":1231,"geoPoint":1235,"contacts":1236},"UH Seidman Cancer Center at Lake Health Mentor Campus","Mentor","44060",{"type":124,"coordinates":1232},[1233,1234],-81.33955,41.66616,{"lat":1234,"lon":1233},[1237,1238],{"name":131,"role":132,"phone":1121,"phoneExt":113,"email":1122},{"name":1124,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1240,"status":117,"city":1241,"state":1112,"zip":1242,"country":121,"countryCode":122,"cosmosGeoPoint":1243,"geoPoint":1247,"contacts":1248},"University Hospitals Parma Medical Center","Parma","44129",{"type":124,"coordinates":1244},[1245,1246],-81.72291,41.40477,{"lat":1246,"lon":1245},[1249,1250],{"name":131,"role":132,"phone":1121,"phoneExt":113,"email":1122},{"name":1124,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1252,"status":117,"city":1253,"state":1112,"zip":1254,"country":121,"countryCode":122,"cosmosGeoPoint":1255,"geoPoint":1259,"contacts":1260},"UH Seidman Cancer Center at Saint John Medical Center","Westlake","44145",{"type":124,"coordinates":1256},[1257,1258],-81.91792,41.45532,{"lat":1258,"lon":1257},[1261,1262],{"name":131,"role":132,"phone":1121,"phoneExt":113,"email":1122},{"name":1124,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1264,"status":117,"city":1265,"state":1266,"zip":1267,"country":121,"countryCode":122,"cosmosGeoPoint":1268,"geoPoint":1272,"contacts":1273},"University of Oklahoma Health Sciences Center","Oklahoma City","Oklahoma","73104",{"type":124,"coordinates":1269},[1270,1271],-97.51643,35.46756,{"lat":1271,"lon":1270},[1274,1277],{"name":131,"role":132,"phone":1275,"phoneExt":113,"email":1276},"405-271-8777","ou-clinical-trials@ouhsc.edu",{"name":1278,"role":112,"phone":113,"phoneExt":113,"email":113},"Christina Washington",{"facility":1280,"status":117,"city":1281,"state":1266,"zip":1282,"country":121,"countryCode":122,"cosmosGeoPoint":1283,"geoPoint":1287,"contacts":1288},"Oklahoma Cancer Specialists and Research Institute-Tulsa","Tulsa","74146",{"type":124,"coordinates":1284},[1285,1286],-95.99277,36.15398,{"lat":1286,"lon":1285},[1289,1291],{"name":131,"role":132,"phone":1290,"phoneExt":113,"email":113},"918-505-3200",{"name":1292,"role":112,"phone":113,"phoneExt":113,"email":113},"Katherine M. Moxley",{"facility":1294,"status":138,"city":1295,"state":1296,"zip":1297,"country":121,"countryCode":122,"cosmosGeoPoint":1298,"geoPoint":1302,"contacts":113},"Saint Alphonsus Cancer Care Center-Ontario","Ontario","Oregon","97914",{"type":124,"coordinates":1299},[1300,1301],-116.96294,44.02655,{"lat":1301,"lon":1300},{"facility":1304,"status":117,"city":1305,"state":1296,"zip":1306,"country":121,"countryCode":122,"cosmosGeoPoint":1307,"geoPoint":1311,"contacts":1312},"Providence Portland Medical Center","Portland","97213",{"type":124,"coordinates":1308},[1309,1310],-122.67621,45.52345,{"lat":1310,"lon":1309},[1313,1316],{"name":131,"role":132,"phone":1314,"phoneExt":113,"email":1315},"503-215-2614","CanRsrchStudies@providence.org",{"name":177,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1318,"status":117,"city":1305,"state":1296,"zip":1319,"country":121,"countryCode":122,"cosmosGeoPoint":1320,"geoPoint":1322,"contacts":1323},"Providence Saint Vincent Medical Center","97225",{"type":124,"coordinates":1321},[1309,1310],{"lat":1310,"lon":1309},[1324,1325],{"name":131,"role":132,"phone":1314,"phoneExt":113,"email":1315},{"name":177,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1327,"status":117,"city":1328,"state":1329,"zip":1330,"country":121,"countryCode":122,"cosmosGeoPoint":1331,"geoPoint":1335,"contacts":1336},"UPMC-Heritage Valley Health System Beaver","Beaver","Pennsylvania","15009",{"type":124,"coordinates":1332},[1333,1334],-80.30478,40.69534,{"lat":1334,"lon":1333},[1337,1340],{"name":131,"role":132,"phone":1338,"phoneExt":113,"email":1339},"412-389-5208","haneydl@upmc.edu",{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},"Alexander B. Olawaiye",{"facility":1343,"status":117,"city":1344,"state":1329,"zip":1345,"country":121,"countryCode":122,"cosmosGeoPoint":1346,"geoPoint":1350,"contacts":1351},"UPMC Hillman Cancer Center at Butler Health System","Butler","16001",{"type":124,"coordinates":1347},[1348,1349],-79.89533,40.86118,{"lat":1349,"lon":1348},[1352,1353],{"name":131,"role":132,"phone":1338,"phoneExt":113,"email":1339},{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1355,"status":117,"city":1356,"state":1329,"zip":1357,"country":121,"countryCode":122,"cosmosGeoPoint":1358,"geoPoint":1362,"contacts":1363},"UPMC Hillman Cancer Center - Passavant - Cranberry","Cranberry Township","16066",{"type":124,"coordinates":1359},[1360,1361],-80.10714,40.68496,{"lat":1361,"lon":1360},[1364,1365],{"name":131,"role":132,"phone":1338,"phoneExt":113,"email":1339},{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1367,"status":117,"city":1368,"state":1329,"zip":1369,"country":121,"countryCode":122,"cosmosGeoPoint":1370,"geoPoint":1374,"contacts":1375},"UPMC Hillman Cancer Center Erie","Erie","16505",{"type":124,"coordinates":1371},[1372,1373],-80.08506,42.12922,{"lat":1373,"lon":1372},[1376,1379],{"name":131,"role":132,"phone":1377,"phoneExt":113,"email":1378},"412-864-7716","ClinicalResearchServices@upmc.edu",{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1381,"status":117,"city":1382,"state":1329,"zip":1383,"country":121,"countryCode":122,"cosmosGeoPoint":1384,"geoPoint":1388,"contacts":1389},"UPMC Cancer Center at UPMC Horizon","Farrell","16121",{"type":124,"coordinates":1385},[1386,1387],-80.49674,41.21228,{"lat":1387,"lon":1386},[1390,1391],{"name":131,"role":132,"phone":435,"phoneExt":113,"email":436},{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1393,"status":117,"city":1394,"state":1329,"zip":1395,"country":121,"countryCode":122,"cosmosGeoPoint":1396,"geoPoint":1400,"contacts":1401},"UPMC Cancer Centers - Arnold Palmer Pavilion","Greensburg","15601",{"type":124,"coordinates":1397},[1398,1399],-79.53893,40.30146,{"lat":1399,"lon":1398},[1402,1404],{"name":131,"role":132,"phone":1403,"phoneExt":113,"email":113},"724-838-1900",{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1406,"status":117,"city":352,"state":1329,"zip":1407,"country":121,"countryCode":122,"cosmosGeoPoint":1408,"geoPoint":1412,"contacts":1413},"IRMC Cancer Center","15701",{"type":124,"coordinates":1409},[1410,1411],-79.15253,40.62146,{"lat":1411,"lon":1410},[1414,1415],{"name":131,"role":132,"phone":1338,"phoneExt":113,"email":1339},{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1417,"status":117,"city":1418,"state":1329,"zip":1419,"country":121,"countryCode":122,"cosmosGeoPoint":1420,"geoPoint":1424,"contacts":1425},"UPMC-Johnstown\u002FJohn P. Murtha Regional Cancer Center","Johnstown","15901",{"type":124,"coordinates":1421},[1422,1423],-78.92197,40.32674,{"lat":1423,"lon":1422},[1426,1428],{"name":131,"role":132,"phone":1427,"phoneExt":113,"email":113},"814-534-4724",{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1430,"status":117,"city":1431,"state":1329,"zip":1432,"country":121,"countryCode":122,"cosmosGeoPoint":1433,"geoPoint":1437,"contacts":1438},"UPMC Cancer Center at UPMC McKeesport","McKeesport","15132",{"type":124,"coordinates":1434},[1435,1436],-79.86422,40.34785,{"lat":1436,"lon":1435},[1439,1441],{"name":131,"role":132,"phone":1440,"phoneExt":113,"email":113},"412-647-8073",{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1443,"status":117,"city":1444,"state":1329,"zip":1445,"country":121,"countryCode":122,"cosmosGeoPoint":1446,"geoPoint":1450,"contacts":1451},"UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion","Mechanicsburg","17050",{"type":124,"coordinates":1447},[1448,1449],-77.00859,40.21426,{"lat":1449,"lon":1448},[1452,1453],{"name":131,"role":132,"phone":1338,"phoneExt":113,"email":1339},{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1455,"status":117,"city":1456,"state":1329,"zip":1457,"country":121,"countryCode":122,"cosmosGeoPoint":1458,"geoPoint":1462,"contacts":1463},"UPMC Hillman Cancer Center - Monroeville","Monroeville","15146",{"type":124,"coordinates":1459},[1460,1461],-79.7881,40.42118,{"lat":1461,"lon":1460},[1464,1465],{"name":131,"role":132,"phone":1377,"phoneExt":113,"email":1378},{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1467,"status":117,"city":1468,"state":1329,"zip":1469,"country":121,"countryCode":122,"cosmosGeoPoint":1470,"geoPoint":1474,"contacts":1475},"UPMC Hillman Cancer Center in Coraopolis","Moon Township","15108",{"type":124,"coordinates":1471},[1472,1473],-80.23923,40.50896,{"lat":1473,"lon":1472},[1476,1477],{"name":131,"role":132,"phone":1338,"phoneExt":113,"email":1339},{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1479,"status":117,"city":1480,"state":1329,"zip":1481,"country":121,"countryCode":122,"cosmosGeoPoint":1482,"geoPoint":1486,"contacts":1487},"UPMC Hillman Cancer Center - Part of Frick Hospital","Mount Pleasant","15666",{"type":124,"coordinates":1483},[1484,1485],-75.18295,40.06011,{"lat":1485,"lon":1484},[1488,1489],{"name":131,"role":132,"phone":1338,"phoneExt":113,"email":1339},{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1491,"status":117,"city":1492,"state":1329,"zip":1493,"country":121,"countryCode":122,"cosmosGeoPoint":113,"geoPoint":113,"contacts":1494},"Arnold Palmer Cancer Center Medical Oncology Norwin","N. Huntingdon","15642",[1495,1496],{"name":131,"role":132,"phone":1377,"phoneExt":113,"email":1378},{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1498,"status":117,"city":1499,"state":1329,"zip":1500,"country":121,"countryCode":122,"cosmosGeoPoint":1501,"geoPoint":1505,"contacts":1506},"UPMC Cancer Center-Natrona Heights","Natrona Heights","15065",{"type":124,"coordinates":1502},[1503,1504],-79.72977,40.6234,{"lat":1504,"lon":1503},[1507,1509],{"name":131,"role":132,"phone":1508,"phoneExt":113,"email":113},"724-230-3030",{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1511,"status":117,"city":1512,"state":1329,"zip":1513,"country":121,"countryCode":122,"cosmosGeoPoint":1514,"geoPoint":1518,"contacts":1519},"UPMC Hillman Cancer Center - New Castle","New Castle","16105",{"type":124,"coordinates":1515},[1516,1517],-80.34701,41.00367,{"lat":1517,"lon":1516},[1520,1521],{"name":131,"role":132,"phone":1338,"phoneExt":113,"email":1339},{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1523,"status":117,"city":1524,"state":1329,"zip":1525,"country":121,"countryCode":122,"cosmosGeoPoint":1526,"geoPoint":1530,"contacts":1531},"UPMC-Magee Womens Hospital","Pittsburgh","15213",{"type":124,"coordinates":1527},[1528,1529],-79.99589,40.44062,{"lat":1529,"lon":1528},[1532,1534],{"name":131,"role":132,"phone":1533,"phoneExt":113,"email":113},"412-647-2811",{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1536,"status":117,"city":1524,"state":1329,"zip":1537,"country":121,"countryCode":122,"cosmosGeoPoint":1538,"geoPoint":1540,"contacts":1541},"UPMC-Saint Margaret","15215",{"type":124,"coordinates":1539},[1528,1529],{"lat":1529,"lon":1528},[1542,1544],{"name":131,"role":132,"phone":1543,"phoneExt":113,"email":113},"412-784-4900",{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1546,"status":117,"city":1524,"state":1329,"zip":1547,"country":121,"countryCode":122,"cosmosGeoPoint":1548,"geoPoint":1550,"contacts":1551},"UPMC-Mercy Hospital","15219",{"type":124,"coordinates":1549},[1528,1529],{"lat":1529,"lon":1528},[1552,1554],{"name":131,"role":132,"phone":1553,"phoneExt":113,"email":113},"800-533-8762",{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1556,"status":117,"city":1524,"state":1329,"zip":1557,"country":121,"countryCode":122,"cosmosGeoPoint":1558,"geoPoint":1560,"contacts":1561},"University of Pittsburgh Cancer Institute (UPCI)","15232",{"type":124,"coordinates":1559},[1528,1529],{"lat":1529,"lon":1528},[1562,1563],{"name":131,"role":132,"phone":1440,"phoneExt":113,"email":113},{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1565,"status":117,"city":1524,"state":1329,"zip":1566,"country":121,"countryCode":122,"cosmosGeoPoint":1567,"geoPoint":1569,"contacts":1570},"UPMC-Passavant Hospital","15237",{"type":124,"coordinates":1568},[1528,1529],{"lat":1529,"lon":1528},[1571,1573],{"name":131,"role":132,"phone":1572,"phoneExt":113,"email":113},"412-367-6454",{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1575,"status":117,"city":1524,"state":1329,"zip":1576,"country":121,"countryCode":122,"cosmosGeoPoint":1577,"geoPoint":1579,"contacts":1580},"UPMC-Saint Clair Hospital Cancer Center","15243",{"type":124,"coordinates":1578},[1528,1529],{"lat":1529,"lon":1528},[1581,1583],{"name":131,"role":132,"phone":1582,"phoneExt":113,"email":113},"412-502-3920",{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1585,"status":117,"city":1586,"state":1329,"zip":1587,"country":121,"countryCode":122,"cosmosGeoPoint":1588,"geoPoint":1592,"contacts":1593},"UPMC Cancer Center at UPMC Northwest","Seneca","16346",{"type":124,"coordinates":1589},[1590,1591],-79.70394,41.37867,{"lat":1591,"lon":1590},[1594,1596],{"name":131,"role":132,"phone":1595,"phoneExt":113,"email":113},"814-676-7900",{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1598,"status":117,"city":1599,"state":1329,"zip":1600,"country":121,"countryCode":122,"cosmosGeoPoint":1601,"geoPoint":1605,"contacts":1606},"UPMC Cancer Center-Washington","Washington","15301",{"type":124,"coordinates":1602},[1603,1604],-80.24617,40.17396,{"lat":1604,"lon":1603},[1607,1608],{"name":131,"role":132,"phone":435,"phoneExt":113,"email":436},{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1610,"status":117,"city":1611,"state":1329,"zip":1612,"country":121,"countryCode":122,"cosmosGeoPoint":1613,"geoPoint":1617,"contacts":1618},"UPMC West Mifflin-Cancer Center Jefferson","West Mifflin","15122",{"type":124,"coordinates":1614},[1615,1616],-79.86644,40.3634,{"lat":1616,"lon":1615},[1619,1621],{"name":131,"role":132,"phone":1620,"phoneExt":113,"email":113},"412-653-8100",{"name":1341,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1623,"status":117,"city":1624,"state":1625,"zip":1626,"country":121,"countryCode":122,"cosmosGeoPoint":1627,"geoPoint":1631,"contacts":1632},"Women and Infants Hospital","Providence","Rhode Island","02905",{"type":124,"coordinates":1628},[1629,1630],-71.41283,41.82399,{"lat":1630,"lon":1629},[1633,1635],{"name":131,"role":132,"phone":1634,"phoneExt":113,"email":113},"401-274-1122",{"name":1636,"role":112,"phone":113,"phoneExt":113,"email":113},"Cara A. Mathews",{"facility":1638,"status":117,"city":1639,"state":1640,"zip":1641,"country":121,"countryCode":122,"cosmosGeoPoint":1642,"geoPoint":1646,"contacts":1647},"Parkland Memorial Hospital","Dallas","Texas","75235",{"type":124,"coordinates":1643},[1644,1645],-96.80667,32.78306,{"lat":1645,"lon":1644},[1648,1651],{"name":131,"role":132,"phone":1649,"phoneExt":113,"email":1650},"214-590-5582","canceranswerline@UTSouthwestern.edu",{"name":1652,"role":112,"phone":113,"phoneExt":113,"email":113},"David S. Miller",{"facility":1654,"status":117,"city":1639,"state":1640,"zip":1655,"country":121,"countryCode":122,"cosmosGeoPoint":1656,"geoPoint":1658,"contacts":1659},"UT Southwestern\u002FSimmons Cancer Center-Dallas","75390",{"type":124,"coordinates":1657},[1644,1645],{"lat":1645,"lon":1644},[1660,1662],{"name":131,"role":132,"phone":1661,"phoneExt":113,"email":1650},"214-648-7097",{"name":1652,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1664,"status":117,"city":1665,"state":1640,"zip":1666,"country":121,"countryCode":122,"cosmosGeoPoint":1667,"geoPoint":1671,"contacts":1672},"UT Southwestern\u002FSimmons Cancer Center-Fort Worth","Fort Worth","76104",{"type":124,"coordinates":1668},[1669,1670],-97.32085,32.72541,{"lat":1670,"lon":1669},[1673,1674],{"name":131,"role":132,"phone":1661,"phoneExt":113,"email":1650},{"name":1652,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1676,"status":117,"city":1677,"state":1640,"zip":1678,"country":121,"countryCode":122,"cosmosGeoPoint":1679,"geoPoint":1683,"contacts":1684},"UT Southwestern Clinical Center at Richardson\u002FPlano","Richardson","75080",{"type":124,"coordinates":1680},[1681,1682],-96.72972,32.94818,{"lat":1682,"lon":1681},[1685,1688],{"name":131,"role":132,"phone":1686,"phoneExt":113,"email":1687},"972-669-7044","Suzanne.cole@utsouthwestern.edu",{"name":1652,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1690,"status":117,"city":1691,"state":834,"zip":1692,"country":121,"countryCode":122,"cosmosGeoPoint":1693,"geoPoint":1697,"contacts":1698},"University of Virginia Cancer Center","Charlottesville","22908",{"type":124,"coordinates":1694},[1695,1696],-78.47668,38.02931,{"lat":1696,"lon":1695},[1699,1702],{"name":131,"role":132,"phone":1700,"phoneExt":113,"email":1701},"434-243-6303","uvacancertrials@hscmail.mcc.virginia.edu",{"name":1703,"role":112,"phone":113,"phoneExt":113,"email":113},"Linda R. Duska",{"facility":1705,"status":117,"city":1706,"state":834,"zip":1707,"country":121,"countryCode":122,"cosmosGeoPoint":1708,"geoPoint":1712,"contacts":1713},"Henrico Doctor's Hospital","Richmond","23229",{"type":124,"coordinates":1709},[1710,1711],-77.46026,37.55376,{"lat":1711,"lon":1710},[1714,1716],{"name":131,"role":132,"phone":1715,"phoneExt":113,"email":113},"804-591-4152",{"name":1717,"role":112,"phone":113,"phoneExt":113,"email":113},"Andrew S. Kennedy",{"facility":1719,"status":1018,"city":1706,"state":834,"zip":1720,"country":121,"countryCode":122,"cosmosGeoPoint":1721,"geoPoint":1723,"contacts":113},"VCU Massey Comprehensive Cancer Center","23298",{"type":124,"coordinates":1722},[1710,1711],{"lat":1711,"lon":1710},{"facility":1725,"status":117,"city":1726,"state":1599,"zip":1727,"country":121,"countryCode":122,"cosmosGeoPoint":1728,"geoPoint":1732,"contacts":1733},"Swedish Cancer Institute-Edmonds","Edmonds","98026",{"type":124,"coordinates":1729},[1730,1731],-122.37736,47.81065,{"lat":1731,"lon":1730},[1734,1737],{"name":131,"role":132,"phone":1735,"phoneExt":113,"email":1736},"206-215-2343","PCRC-NCORP@Swedish.org",{"name":177,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1739,"status":117,"city":1740,"state":1599,"zip":1741,"country":121,"countryCode":122,"cosmosGeoPoint":1742,"geoPoint":1746,"contacts":1747},"Swedish Cancer Institute-Issaquah","Issaquah","98029",{"type":124,"coordinates":1743},[1744,1745],-122.03262,47.5301,{"lat":1745,"lon":1744},[1748,1749],{"name":131,"role":132,"phone":1735,"phoneExt":113,"email":1736},{"name":177,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1751,"status":1018,"city":1752,"state":1599,"zip":1753,"country":121,"countryCode":122,"cosmosGeoPoint":1754,"geoPoint":1758,"contacts":113},"Fred Hutchinson Cancer Center","Seattle","98109",{"type":124,"coordinates":1755},[1756,1757],-122.33207,47.60621,{"lat":1757,"lon":1756},{"facility":1760,"status":117,"city":1752,"state":1599,"zip":1761,"country":121,"countryCode":122,"cosmosGeoPoint":1762,"geoPoint":1764,"contacts":1765},"Swedish Medical Center-First Hill","98122",{"type":124,"coordinates":1763},[1756,1757],{"lat":1757,"lon":1756},[1766,1767],{"name":131,"role":132,"phone":1735,"phoneExt":113,"email":1736},{"name":177,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1769,"status":117,"city":1770,"state":1771,"zip":1772,"country":121,"countryCode":122,"cosmosGeoPoint":1773,"geoPoint":1777,"contacts":1778},"Duluth Clinic Ashland","Ashland","Wisconsin","54806",{"type":124,"coordinates":1774},[1775,1776],-90.8838,46.59244,{"lat":1776,"lon":1775},[1779,1780],{"name":131,"role":132,"phone":715,"phoneExt":113,"email":716},{"name":718,"role":112,"phone":113,"phoneExt":113,"email":113},{"facility":1782,"status":117,"city":1770,"state":1771,"zip":1772,"country":121,"countryCode":122,"cosmosGeoPoint":1783,"geoPoint":1785,"contacts":1786},"Northwest Wisconsin Cancer Center",{"type":124,"coordinates":1784},[1775,1776],{"lat":1776,"lon":1775},[1787,1788],{"name":131,"role":132,"phone":715,"phoneExt":113,"email":716},{"name":718,"role":112,"phone":113,"phoneExt":113,"email":113},{"type":1790,"investigatorFullName":113,"investigatorTitle":113,"investigatorAffiliation":113,"oldNameTitle":113,"oldOrganization":113},"SPONSOR",[1792],{"name":111,"class":1793},"OTHER","100447912","phase-2-testing-nivolumab-with-or-without-ipilimumab-in-deficient-mismatch-repair-system-dmmr-recurrent-endometrial-carcinoma-100447912",false,"NCT05112601","Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma","A Randomized Phase II Trial of Nivolumab and Ipilimumab Compared to Nivolumab Monotherapy in Patients With Deficient Mismatch Repair System Recurrent Endometrial Carcinoma","Inclusion Criteria:\n\n* Patients with measurable or non-measurable (detectable) recurrent endometrial cancer\n* Measurable disease will be defined and monitored by RECIST v 1.1. Measurable disease is defined per RECIST 1.1 criteria as at least one lesion that can be accurately measured in at least one dimension (longest diameter to be recorded). Each lesion must be \\>= 10 mm when measured by computed tomography (CT) or magnetic resonance imaging (MRI). Lymph nodes must be \\>= 15 mm in short axis when measured by CT or MRI\n* Non-measurable (detectable) disease in a patient is defined in this protocol per RECIST 1.1 criteria as one who does not have measurable disease but has at least one of the following conditions:\n\n  * All other lesions (or sites of disease), including small lesions (longest diameter \\\u003C10 mm or pathological lymph nodes with \\>= 10 to \\\u003C 15 mm short axis), are considered non-measurable disease\n  * Ascites and\u002For pleural effusion attributed to tumor\n  * Solid and\u002For cystic abnormalities on radiographic imaging that do not meet RECIST 1.1 definitions for target lesions\n* Patients must have endometrial cancer with deficient mismatch repair system. All patients must have institutional immunohistochemistry (IHC) and\u002For microsatellite instability (MSI) testing to determine mismatch repair (MMR) status. MMR deficiency is defined as lack of expression of one or more mismatch repair proteins (MLH1, PMS2, MSH2, MSH6, EPCAM) by immunohistochemistry and\u002For presence of microsatellite instability high using the National Cancer Institute (NCI)-5plex and Promega v1.2 assays, or institutional standards (e.g. next-generation sequencing \\[NGS\\] panel)\n\n  * Method(s) of detection of MMR deficiency will be recorded for each patient. An institutional pathology report, and additional reports if available, documenting these results must be submitted. Patients with \"equivocal\" results on MMR testing by immunohistochemistry may be eligible if they have documented evidence of microsatellite instability by MSI testing or by next generation sequencing assays. MMR testing by IHC may be used to resolve equivocal\u002Findeterminate MSI results\n* Histologic confirmation of the original primary tumor is required (submission of pathology report(s) is required). Patients with the following histologic types are eligible: Endometrioid adenocarcinoma, mucinous adenocarcinoma, dedifferentiated\u002Fundifferentiated carcinoma, clear cell adenocarcinoma, mixed epithelial carcinoma, adenocarcinoma not otherwise specified (N.O.S.)\n* Patients may have received 1-2 prior lines of systemic therapy:\n\n  * Prior anti-PD1\u002FPD-L1 therapy is allowed if given in combination with chemotherapy or radiation therapy in adjuvant or primary metastatic\u002Frecurrent settings. Patients must have had a complete response and have disease progression\u002Frelapse with treatment-free interval of 12 months or more from last dose of therapy with immune check inhibition\n* Patients may have received prior radiation therapy for treatment of endometrial cancer. Prior radiation therapy may have included pelvic radiation therapy, extended field pelvic\u002Fpara aortic radiation therapy, intravaginal brachytherapy, and\u002For palliative radiation therapy. All radiation therapy must be completed at least 4 weeks prior to registration\n* Patients may have received prior hormonal therapy for treatment of endometrial cancer. All hormonal therapy must be discontinued at least three weeks prior to registration\n* Any other prior therapy directed at the malignant tumor including chemotherapy, targeted agents, biologic agents, immunologic agents, and any investigational agents, must be discontinued at least 4 weeks prior to registration (6 weeks for nitrosoureas or mitomycin C)\n* Age \\>= 18\n* Eastern Cooperative Oncology Group (ECOG) Performance Status of 0, 1, or 2\n* Platelets \\>= 100,000\u002Fmcl\n* Absolute neutrophil count (ANC) \\>= 1,500\u002Fmcl\n* Creatinine =\\\u003C 1.5 x institutional\u002Flaboratory upper limit of normal (ULN)\n* Total serum bilirubin level =\\\u003C 1.5 x ULN (patients with known Gilbert's disease who have bilirubin level =\\\u003C3 x ULN may be enrolled)\n* Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =\\\u003C 3 x ULN\n* Adequate oxygen saturation via pulse oximeter (CTCAE v.5.0 hypoxia \\\u003C grade 2 within 28 days prior to registration)\n* Thyroid-stimulating hormone (TSH) within normal limits (TSH \\\u003C ULN allowed in euthyroid patients on thyroid replacement therapy). TSH testing is only required if clinically indicated\n* Patients must have recovered from effects of recent surgery, radiotherapy or chemotherapy. At least 4 weeks must have elapsed since major surgery\n* As clinically indicated, patients with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, should have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification. To be eligible for this trial, patients should be class 2B or better and have a corrected QT (QTc) interval \\\u003C 450 msec\n* The effects of nivolumab, and ipilimumab on the developing human fetus are unknown. For this reason and because nivolumab and ipilimumab are known to be teratogenic, women of child-bearing potential (WOCBP) must agree to use adequate contraception (hormonal or barrier method of birth control; abstinence) prior to study entry and for 5 months after the last dose of investigational drug. Women of childbearing potential must have a negative serum or urine pregnancy test (minimum sensitivity 25 IU\u002FL or equivalent units of human chorionic gonadotropin \\[HCG\\]) within 24 hours prior to the start of nivolumab. Women must not be breastfeeding. Women who are not of childbearing potential (i.e., who are postmenopausal or surgically sterile) do not require contraception\n\n  * WOCBP is defined as any female who has experienced menarche and who has not undergone surgical sterilization (hysterectomy or bilateral oophorectomy) or who is not postmenopausal. Menopause is defined clinically as 12 months of amenorrhea in a woman over 45 in the absence of other biological or physiological causes. In addition, women under the age of 55 must have a documented serum follicle stimulating hormone (FSH) level less than 40 mIU\u002FmL\n* Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial\n* Human immunodeficiency virus (HIV)-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months of registration are eligible for this trial\n* Patients with evidence of chronic hepatitis B virus (HBV) infection must have an undetectable HBV viral load on suppressive therapy, if indicated\n* Patients with a history of hepatitis C virus (HCV) infection must have been treated and cured. For patients with HCV infection who are currently on treatment, they are eligible if they have an undetectable HCV viral load\n* Patients with treated brain metastases are eligible if follow-up brain imaging after central nervous system (CNS)-directed therapy shows no evidence of progression and the patient is stable off steroids for at least one month\n* The patient or a legally authorized representative must provide study-specific informed consent prior to study entry and, for patients treated in the United States (U.S.), authorization permitting release of personal health information\n* Patients with vitiligo, endocrine deficiencies including thyroiditis managed with replacement hormones including physiologic corticosteroids are eligible\n* Patients with rheumatoid arthritis and other arthropathies, Sjogren's syndrome and psoriasis controlled with topical medication and patients with positive serology, such as antinuclear antibodies (ANA), anti-thyroid antibodies should be evaluated for the presence of target organ involvement and potential need for systemic treatment but should otherwise be eligible\n\nExclusion Criteria:\n\n* Patients with a diagnosis of endometrial serous carcinoma or carcinosarcoma\n* Patients who received prior anti-PD1\u002FPD-L1 therapy and had grade 3-4 or recurring grade 2 immune-related toxicities that led to dose delay or discontinuation of immunotherapy due to those toxicities\n* Patients who received anti-CTLA-4 therapy or other immunotherapeutic agents\n* Patients on chronic steroid therapy except those on replacement therapy at a daily dose of 10mg or less prednisone or equivalent\n* Patients on immunosuppressive therapy, with the exception of:\n\n  * Intra-nasal, inhaled, topical or local steroid injections\n  * Premedication for hypersensitivity reaction\n* Patients with active autoimmune disease or history of autoimmune disease that might recur, which may affect vital organ function or require immune suppressive treatment including systemic corticosteroids, should be excluded. These include but are not limited to patients with a history of immune related neurologic disease, multiple sclerosis, autoimmune (demyelinating) neuropathy, Guillain-Barre syndrome, myasthenia gravis; systemic autoimmune disease such as systemic lupus erythematosus (SLE), connective tissue diseases, scleroderma, inflammatory bowel disease (IBD), Crohn's, ulcerative colitis, hepatitis; and patients with a history of toxic epidermal necrolysis (TEN), Stevens-Johnson syndrome, or phospholipid syndrome should be excluded because of the risk of recurrence or exacerbation of disease\n* Patients with known immune impairment who may be unable to respond to anti-CTLA-4 antibody\n* Patients with uncontrolled intercurrent illness including, but not limited to: ongoing or active infection (except for uncomplicated urinary tract infection), interstitial lung disease or active, non-infectious pneumonitis, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness\u002Fsocial situations that would limit compliance with study requirements\n* Women who are pregnant or unwilling to discontinue nursing\n* Prior therapy with CTLA-4 inhibitors, or any other antibody or drug specifically targeting T-cell co-stimulation or immune checkpoint pathways\n* History of allergic reactions attributed to compounds of similar chemical or biologic composition to nivolumab, and\u002For ipilimumab including severe hypersensitivity reactions to any monoclonal antibody","FEMALE","18 Years",{"count":1804,"type":1805},81,"ESTIMATED","INTERVENTIONAL",[1808],"PHASE2","This phase II trial tests whether the combination of nivolumab and ipilimumab is better than nivolumab alone to shrink tumors in patients with deficient mismatch repair system (dMMR) endometrial carcinoma that has come back after a period of time during which the cancer could not be detected (recurrent). Deoxyribonucleic acid (DNA) mismatch repair (MMR) is a system for recognizing and repairing damaged DNA. In 2-3% of endometrial cancers this may be due to a hereditary condition resulted from gene mutation called Lynch Syndrome (previously called hereditary nonpolyposis colorectal cancer or HNPCC). MMR deficient cells usually have many DNA mutations. Tumors that have evidence of mismatch repair deficiency tend to be more sensitive to immunotherapy. There is some evidence that nivolumab with ipilimumab can shrink or stabilize cancers with deficient mismatch repair system. However, it is not known whether this will happen in endometrial cancer; therefore, this study is designed to answer that question. Monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving nivolumab in combination with ipilimumab may be better than nivolumab alone in treating dMMR recurrent endometrial carcinoma.",[1811,1812,1813,1814,1815,1816,1817,1818,1819],"Endometrial Adenocarcinoma","Endometrial Clear Cell Adenocarcinoma","Endometrial Dedifferentiated Carcinoma","Endometrial Endometrioid Adenocarcinoma","Endometrial Mixed Cell Adenocarcinoma","Endometrial Mucinous Adenocarcinoma","Endometrial Undifferentiated Carcinoma","Endometrioid Adenocarcinoma","Recurrent Endometrial Carcinoma","2026-06-18",{"date":1822,"type":1823},"2026-06-22","ACTUAL",{"date":1825,"type":1823},"2022-06-02",{"date":1827,"type":1805},"2032-07-30",{"name":5,"class":6},137]