[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100548954":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":30,"centralContacts":41,"locations":52,"responsibleParty":74,"collaborators":30,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":30,"eligibilityCriteria":84,"healthyVolunteers":80,"sex":85,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":30,"studyType":91,"phases":92,"briefSummary":95,"conditions":96,"keywords":30,"overallStatus":54,"whyStopped":30,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Group PLM (propofol-lidocaine-magnesium)","ACTIVE_COMPARATOR","intravenous infusion of propofol, lidocaine and magnesium sulfate.",[13],"Drug: Intravenous Infusion of propofol, lidocaine, Magnesium sulfate",{"label":15,"type":10,"description":16,"interventionNames":17},"Group KLM (ketamine-lidocaine-magnesium)","intravenous infusion of Ketamine, lidocaine and magnesium sulfate",[18],"Drug: Intravenous infusion of ketamine, lidocaine, Magnesium sulfate",{"label":20,"type":10,"description":21,"interventionNames":22},"Group DLM (Dexmeditomidine-lidocaine-magnesium)","Intravenous infusion of Dexmeditomidine, lidocaine and magnesium sulfate",[23],"Drug: Intravenous infusion of dexmedetomidine, lidocaine, Magnesium sulfate",[25,31,35],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"DRUG","Intravenous Infusion of propofol, lidocaine, Magnesium sulfate","intravenous infusion of propofol 6-10 mg.kg-1.h-1, lidocaine (lidocaine 2% 400mg in 20 ml) bolus of 1.5 mg.kg-1 followed by infusion with a rate of 1.5 mg.kg-1.h-1 and magnesium sulfate 40 mg.kg-1 loading followed by infusion of 20 mg.kg-1.h-1. the effect of either Propofol injection, or ketamine injection or dexmeditomidine injection on intraoperative bleeding",[9],null,{"type":26,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"Intravenous infusion of ketamine, lidocaine, Magnesium sulfate","Patients will receive intravenous infusion of Ketamine 0.1-0.2 mg.kg-1.h-1 (intravenous infusion of propofol 6-10 mg.kg-1.h-1, lidocaine (lidocaine 2% 400mg in 20 ml) bolus of 1.5 mg.kg-1 followed by infusion with a rate of 1.5 mg.kg-1.h-1 and magnesium sulfate 40 mg.kg-1 loading followed by infusion of 20 mg.kg-1.h-1. dose of 1 mg.kg-1), lidocaine bolus of 1.5 mg.kg-1 followed by infusion with a rate of 1.5 mg.kg-1.h-1 and magnesium sulfate 40 mg.kg-1 loading followed by infusion of 20 mg.kg-1.h-1.",[15],{"type":26,"name":36,"description":37,"armGroupLabels":38,"otherNames":39},"Intravenous infusion of dexmedetomidine, lidocaine, Magnesium sulfate","Dexmeditomidine (Precedex® 200 mcg.2ml-1) with a rate of 0.2-0.6 mcg.Kg-1.h-1. lidocaine bolus of 1.5 mg.kg-1 followed by infusion with a rate of 1.5 mg.kg-1.h-1 and magnesium sulfate 40 mg.kg-1 loading followed by infusion of 20 mg.kg-1.h-1",[20],[40],"Precedex",[42,48],{"name":43,"role":44,"phone":45,"phoneExt":46,"email":47},"RANIA M Hussien, MD","CONTACT","01000544520","202","drrania_maamon@med.asu.edu.eg",{"name":49,"role":44,"phone":50,"phoneExt":46,"email":51},"Fathy Tash, MD","26857539","REC-FMASU@med.asu.edu.eg",[53],{"facility":5,"status":54,"city":55,"state":56,"zip":57,"country":58,"countryCode":59,"cosmosGeoPoint":60,"geoPoint":65,"contacts":66},"RECRUITING","Cairo","Cairo Governorate","69711","Egypt","EG",{"type":61,"coordinates":62},"Point",[63,64],31.24967,30.06263,{"lat":64,"lon":63},[67,70],{"name":68,"role":44,"phone":69,"phoneExt":46,"email":47},"Rania M Hussien, MD","026213948",{"name":71,"role":44,"phone":72,"phoneExt":46,"email":73},"Hala S El Ozairy, MD","01001191199","hala_elozairy@med.asu.edu.eg",{"type":75,"investigatorFullName":76,"investigatorTitle":77,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"PRINCIPAL_INVESTIGATOR","Rania Maher Hussien, MD","Associate Professor","100548954","phase-2-the-effect-of-adding-either-propofol-or-ketamine-to-magnesium-and-lidocaine-infusions-in-nasal-surgeries-100548954",false,"NCT06427707","The Effect of Adding Either Propofol or Ketamine to Magnesium and Lidocaine Infusions in Nasal Surgeries.","The Effect of Adding Either Propofol or Ketamine to Magnesium and Lidocaine Infusions As an Opioid Free Anaesthesia on Surgical Field in Patients Undergoing Nasal Surgeries. a Randomized Controlled Trial","Inclusion Criteria:\n\n* ASA I-II,\n* scheduled for elective nasal surgery\n\nExclusion Criteria:\n\n* Patients with uncontrolled hypertension.\n* Patients with cardiac disease.\n* Patients with renal, hepatic or cerebral insufficiency.\n* Patients with coagulopathy or receiving drugs influencing blood coagulation.\n* Anaemia, haemoglobinopathies or polycythemia.\n* Pregnancy.\n* Patients with known sensitivity to any of the study drug.","ALL","18 Years","60 Years",{"count":89,"type":90},90,"ESTIMATED","INTERVENTIONAL",[93,94],"PHASE2","PHASE3","Nasal surgeries are common day case procedures. Although surgical complications are rare, bleeding decreases surgical field visibility and may cause vascular, orbital or intracranial complications in addition to failure of procedure. So, it is crucial to maintain hypotensive anaesthesia to optimize the surgical field.",[97],"Intraoperative Bleeding","2024-10-05",{"date":100,"type":101},"2024-10-09","ACTUAL",{"date":103,"type":101},"2024-06-15",{"date":105,"type":90},"2024-10-31",{"name":5,"class":6},1]