[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100579814":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":32,"locations":26,"responsibleParty":39,"collaborators":43,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":26,"eligibilityCriteria":52,"healthyVolunteers":48,"sex":53,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":26,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":68,"whyStopped":26,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":26},{"fullName":5,"class":6},"University of Guadalajara","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"case group","EXPERIMENTAL","curcumin capsules 500 mg every 8 hours for 12 weeks",[13],"Dietary Supplement: Curcumin (Longvida™)",{"label":15,"type":16,"description":17,"interventionNames":18},"control group","PLACEBO_COMPARATOR","placebo group",[19],"Drug: Placebo",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIETARY_SUPPLEMENT","Curcumin (Longvida™)","patients will be suplemented during 3 months with longvida, 2 cap \u002F8 hours",[9],null,{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":26},"DRUG","Placebo","one capsules every 8 hours during 12 weeks",[15],[33],{"name":34,"role":35,"phone":36,"phoneExt":37,"email":38},"Mariana Chávez-Tostado, PhD.","CONTACT","3310585200","52","ln.marianachavez@gmail.com",{"type":40,"investigatorFullName":41,"investigatorTitle":42,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Mariana Chávez-Tostado","Doctor in Multidisciplinary Health Research",[44],{"name":45,"class":6},"Hospital Civil de Guadalajara","100579814","phase-2-the-effect-of-curcumin-on-inflammatory-markers-in-hemodialysis-patients-100579814",false,"NCT06829186","The Effect of Curcumin on Inflammatory Markers in Hemodialysis Patients","Effect of Curcumin on the Reduction of Cellular Inflammation Markers in Hemodialysis Patients","Inclusion Criteria:\n\n* Patients of both sexes undergoing dialysis or hemodialysis.\n* Aged 18 years or older.\n* Clinically stable and receiving hemodialysis or dialysis for at least three months before study enrollment.\n* Continuation of pharmacotherapy as prescribed by their physician.\n* Regular use of antioxidant supplements and turmeric consumption.\n* Signed written informed consent.\n\nExclusion Criteria:\n\n* Active malignant disease (diagnosed within the past five years).\n* Critical illness requiring respiratory or circulatory support.\n* Severe congestive heart failure (NYHA class IV).\n* Severe chronic systemic infectious or inflammatory disease.\n* Severe liver disease.\n* Known allergy to study products.\n* Treatment with immunosuppressants or experimental drugs in the past month.\n* Use of anti-inflammatory corticosteroids.\n* Scheduled kidney transplant during the study.\n* Pregnant patients.\n* Active smokers.\n* Autoimmune diseases, cancer, severe infections, or AIDS.","ALL","18 Years","100 Years",{"count":57,"type":58},70,"ESTIMATED","INTERVENTIONAL",[61],"PHASE2","The goal of this clinical trial is to learn if curcumin can lower the inflammation in participants with chronic kidney disease (CKD) undergoing hemodialysis (HD).\n\nThe main questions it aims to answer are:\n\nDoes curcumin lower can lower profinflamatory markers in participants with CKD on HD?\n\nResearchers will compare curcumin to a placebo (a look-alike substance that contains no drug) to see if curcumin works to help the treatment in participants with CKD on HD.\n\nResearchers will compare nutritional status and side effects after taking the supplement.\n\nParticipants will:\n\nTake the curcumin or a placebo twice a day for 3 months Visit the clinic once every week for checkups and tests.",[64],"Hemodialysis",[66,64,67],"CURCUMIN","INFLAMMATION","NOT_YET_RECRUITING","2025-02-10",{"date":71,"type":72},"2025-02-17","ACTUAL",{"date":74,"type":58},"2025-03-15",{"date":76,"type":58},"2026-12-30",{"name":5,"class":6}]