[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100613467":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":39,"responsibleParty":53,"collaborators":25,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":25,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":25,"studyType":70,"phases":71,"briefSummary":74,"conditions":75,"keywords":78,"overallStatus":81,"whyStopped":25,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Margalla Institute of Health Sciences","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A , AH plus sealer , Group B ( bioceramic sealer)","ACTIVE_COMPARATOR","patients in group A will recieve AH plus sealer and in group B shall recieve bioceramic sealer for obturation during root canal treatment",[13],"Drug: bioceramic sealer",{"label":15,"type":10,"description":16,"interventionNames":17},"Group A , (AH plus sealer ) , Group B ( bioceramic sealer)","patients in Group A will recieve Ah plus sealer for obturation and patients in group B shall recieve bioceramic sealer for obtration during root canal treatment second visit",[18],"Drug: AH-Plus Epoxy Resin Sealer",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","AH-Plus Epoxy Resin Sealer","AH plus sealer is an epoxy resin based sealer that is biocompatible with good sealing ability",[15],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"bioceramic sealer","MTA based sealers,biocermic sealers are biocompatible, safe to use",[9],[31,36],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Jaweria gul keyani","CONTACT","+ 92 3312931111","jaweriagulkeyani@gmail.com",{"name":37,"role":33,"phone":38,"phoneExt":25,"email":25},"Dr lubna Pasha","+92 333 9499959",[40],{"facility":41,"status":25,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":25},"Margalla Institute of Health Sciences, Gulraiz phase III Quaid e azam Avenue, Rawalpindi","Rawalpindi","Punjab Province","46000","Pakistan","PK",{"type":48,"coordinates":49},"Point",[50,51],73.0479,33.59733,{"lat":51,"lon":50},{"type":54,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"SPONSOR_INVESTIGATOR","Jaweria Gul Keyani","Post Graduate Trainee","100613467","phase-2-to-evaluate-post-operative-pain-using-two-different-kind-of-sealers-in-obturation-of-teeth-with-symptomatic-irreversible-pulpitis-during-second-visit-when-the-patient-is-painless-100613467",false,"NCT07266974","To Evaluate Post Operative Pain Using Two Different Kind of Sealers in Obturation of Teeth With Symptomatic Irreversible Pulpitis During Second Visit When the Patient is Painless","Evaluation of Post -Operative Pain After Obturation Using Two Different Types of Sealers - A Randomized Clinical Trial","Inclusion Criteria:\n\n* • Patients ranging from 18 to 40 years.\n\n  * Patients whose teeth have been diagnosed with Symptomatic irreversible pulpitis.\n  * maxillary and mandibular teeth.\n  * A normal periapical condition on radiograph, or one with little to no periodontal ligament (PDL) space widening, confirming the normal periapical state.\n  * Teeth that can be restored.\n  * Teeth with healthy periodontium.\n\nExclusion Criteria:\n\n* Non-restorable teeth.\n* Patients with poor health whose systemic complications could change the course of treatment.\n* Teeth with immature roots.\n* Teeth with periapical lesions or apical periodontitis.\n* Teeth with Necrotic pulp.","ALL","18 Years","40 Years",{"count":68,"type":69},60,"ESTIMATED","INTERVENTIONAL",[72,73],"PHASE2","PHASE3","The goal of this randomized clinical trial is to evaluate pain after root canal treatment using two different kinds of sealers during obturation in 60 healthy , male and female patients ages between 18 to 40 years. The main aims is to systematically evaluate and compare post-operative pain levels in patients undergoing root canal treatment with two different types of endodontic sealers: AH plus (SEAL APEX) and bio ceramic sealer(META)\n\n• By identifying the sealer that leads to the least discomfort, this research could significantly enhance patient care, minimize recovery time, and improve overall treatment success in endodontics.\n\nParticipants in both groups will be given a visual analogue scale(VAS) to measure the pain level after the root canal treatment has been completed. They will measure pain levels at 12, 24 and 48 hours. All information will be recorded on proforma and compared.",[76,77],"Post Operative Pain, Acute","Irreversible Pulpitis",[79,27,80],"post operative pain","irreversible pulpitis","NOT_YET_RECRUITING","2026-01-06",{"date":84,"type":85},"2026-01-08","ACTUAL",{"date":87,"type":69},"2026-04-01",{"date":89,"type":69},"2026-10-01",{"name":55,"class":6},1]