[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100579243":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":39,"responsibleParty":58,"collaborators":25,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":25,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":25,"studyType":74,"phases":75,"briefSummary":78,"conditions":79,"keywords":25,"overallStatus":82,"whyStopped":25,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Margalla Institute of Health Sciences","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A( calcium hydroxide)","ACTIVE_COMPARATOR","patients receiving calcium hydroxide as intra canal medicament",[13],"Drug: Calcium Hydroxide Intracanal medication",{"label":15,"type":10,"description":16,"interventionNames":17},"Group B( Triple Antibiotic Paste)","Patients receiving triple antibiotic paste as intra canal medicament",[18],"Drug: triple antibiotic paste (TAP)",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Calcium Hydroxide Intracanal medication","non setting calcium hydroxide(CH) mixed with normal saline and placed as intra canal medicament during first visit of root canal treatment. effectiveness measured after 48hrs, 72hrs and 96hrs",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"triple antibiotic paste (TAP)","mix metronidazole, ciprofloxacin and minocycline in ratio 1:1:1 with normal saline and placed as intra canal medicament during first visit of root canal treatment.",[15],[31,36],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Komal Ashraf Khan","CONTACT","+92 3129433556","komalashraf152@gmail.com",{"name":37,"role":33,"phone":38,"phoneExt":25,"email":25},"Dr. Lubna Pasha","+92 333 9499959",[40],{"facility":41,"status":25,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Margalla Institute Of Health Sciences Quaid e Azam Avenue, Gulraiz phase 3, Gulraiz housing scheme Rawalpindi","Rawalpindi","Punjab Province","46000","Pakistan","PK",{"type":48,"coordinates":49},"Point",[50,51],73.0479,33.59733,{"lat":51,"lon":50},[54],{"name":55,"role":33,"phone":56,"phoneExt":25,"email":57},"Prof Dr Amjad Mehmood Dean MIHS","051-5509640","hod_cdm@margalla.edu.pk",{"type":59,"investigatorFullName":32,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"SPONSOR_INVESTIGATOR","Post Graduate Trainee","100579243","phase-2-to-measure-post-operative-pain-severity-by-using-two-different-intra-canal-medicaments-calcium-hydroxide-and-triple-antibiotic-paste-in-teeth-with-single-roots-and-periapical-disease-called-apical-periodontitis-100579243",false,"NCT06821763","To Measure Post Operative Pain Severity by Using Two Different Intra Canal Medicaments Calcium Hydroxide and Triple Antibiotic Paste in Teeth with Single Roots and Periapical Disease Called Apical Periodontitis","Effect of Calcium Hydroxide on Post Operative Pain Severity in Single Rooted Teeth with Symptomatic Apical Periodontitis","Inclusion Criteria:\n\n* Patients of both genders having age 12-45 years\n* Newly diagnosed cases fulfilling the criteria of INTERNATIONAL ASSOCIATES FOR THE STUDY OF PAIN definition of pain.\n* A Single rooted teeth (Anterior or Posterior)\n* Teeth with symptomatic apical periodontitis\n* Teeth with necrotic pulp that gave a negative response to vitality testing.\n\nExclusion Criteria:\n\n* Patients who have allergies, sensitivity or unable to take medications, periodontal disease, acute endodontic or periodontal abscess, requiring prophylactic antibiotics, systemic diseases like hypertension, diabetes, liver dysfunction renal failure and mental disabilities were excluded.\n* Pregnant ladies or patients on nursing were also excluded from the sample.\n* Teeth with anatomical difficulties such as open apices.\n* Teeth with severe dilacerations, calcified canals, occlusal interferences, chronic periodontitis, internal\u002Fexternal root resorption.\n* Patients with serious medical illness, systemic disorders, immunocompromised diseases such as AIDS or HBV.","ALL","12 Years","45 Years",{"count":72,"type":73},180,"ESTIMATED","INTERVENTIONAL",[76,77],"PHASE2","PHASE3","* The aim of this study is to compare post operative pain effectiveness between two most commonly available intra canal medicaments that are Triple Antibiotic Paste and Calcium Hydroxide during root canal treatment of single rooted teeth with symptomatic apical periodontitis.\n* Patients visiting OPD will be selected after fulfilment of inclusion criteria and randomly divided into two groups i.e group A patients receiving calcium hydroxide and group B with patients receiving Triple Antibiotic Paste as intra canal medicaments\n* Patient will be called at 48hrs 72hrs and 96hrs postoperatively.\n* Effectiveness of intra canal medicaments will be measured as no mild moderate severe on visual analogue scale(VAS).",[80,81],"Apical Periodontitis","Irreversible Pulpitis with Apical Periodontitis","NOT_YET_RECRUITING","2025-02-10",{"date":85,"type":86},"2025-02-12","ACTUAL",{"date":88,"type":73},"2025-05-01",{"date":90,"type":73},"2025-11-01",{"name":32,"class":6},1]