[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100619065":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":38,"locations":47,"responsibleParty":65,"collaborators":11,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":11,"eligibilityCriteria":74,"healthyVolunteers":70,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":11,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":11,"overallStatus":49,"whyStopped":11,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"West China Hospital","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Zishui Daohuo oral liquid combined with Kujiu mouthwash group.","EXPERIMENTAL",null,[13,14],"Drug: Zishui Daohuo oral liquid combined with Kujiu mouthwash","Radiation: Radiotherapy",{"label":16,"type":17,"description":11,"interventionNames":18},"Placebo oral liquid and mouthwash","PLACEBO_COMPARATOR",[19,14],"Drug: Placebo oral liquid and mouthwash",[21,25,29],{"type":22,"name":16,"description":23,"armGroupLabels":24,"otherNames":11},"DRUG","Placebo oral liquid and mouthwash with the same color, aroma, and taste as the experimental group, and without any related drug ingredients",[16],{"type":22,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"Zishui Daohuo oral liquid combined with Kujiu mouthwash","Oral administration of Zishui Daohuo oral liquid combined with gargling using Kujiu mouthwash.",[9],{"type":30,"name":31,"description":32,"armGroupLabels":33,"otherNames":11},"RADIATION","Radiotherapy","One of the inclusion criteria for the study was that patients with squamous carcinoma of the head and neck (including nasopharyngeal carcinoma) needed to receive either radiotherapy alone or simultaneous radiotherapy and chemotherapy.",[16,9],[35],{"name":36,"affiliation":5,"role":37},"Xingchen Peng, Professor","PRINCIPAL_INVESTIGATOR",[39,44],{"name":40,"role":41,"phone":42,"phoneExt":11,"email":43},"Xingchen Peng Professor","CONTACT","+8618980606753","pxx2014@163.com",{"name":45,"role":41,"phone":11,"phoneExt":11,"email":46},"JiaYi Yu Doctor","yujiayi2209@163.com",[48],{"facility":5,"status":49,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"RECRUITING","Chengdu","Sichuan","610041","China","CN",{"type":56,"coordinates":57},"Point",[58,59],104.06667,30.66667,{"lat":59,"lon":58},[62],{"name":63,"role":41,"phone":64,"phoneExt":11,"email":43},"Xingchen Peng Ph.D","18980606753",{"type":37,"investigatorFullName":66,"investigatorTitle":67,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Xingchen Peng","Ph.D","100619065","phase-2-traditional-chinese-medicine-preparation-alleviates-radiotherapy-induced-oral-mucositis-in-head-and-neck-cancer-patients-100619065",false,"NCT07339774","Traditional Chinese Medicine Preparation Alleviates Radiotherapy-induced Oral Mucositis in Head and Neck Cancer Patients.","Chinese Herbal Oral Solution and Mouthwash Shorten the Duration of Severe Radiotherapy-induced Oral Mucositis in Patients With Head and Neck Malignancies.","Inclusion Criteria:\n\n1. Patients pathologically diagnosed with non-metastatic head and neck malignant tumors;\n2. Age range: 18 to 65 years old (including 18 and 65 years old);\n3. Eastern Cooperative Oncology Group performance status of ≤2;\n4. Radiotherapy or concurrent chemoradiotherapy is required;\n5. The main organ functions well;\n6. Sign informed consent.\n\nExclusion Criteria:\n\n1. Allergic constitution (such as those known to be allergic to two or more drugs);\n2. Patients who plan to use drugs that can cause or worsen oral mucosal inflammation (such as anti EGFR monoclonal antibodies, immune checkpoint inhibitors, etc.) after the start of radiotherapy;\n3. Use of antibiotics, antifungal drugs, or antimicrobial mouthwash within 1 month of the study;\n4. Poor oral hygiene and\u002For severe periodontal diseases;\n5. History of head and neck radiotherapy;\n6. Deemed unsuitable for the study by the investigators (concomitant with any other severe diseases).","ALL","18 Years","65 Years",{"count":79,"type":80},128,"ESTIMATED","INTERVENTIONAL",[83],"PHASE2","Evaluate the effectiveness and safety of traditional Chinese medicine compound in improving radiotherapy-induced oral mucositis in patients with head and neck malignant tumors.",[86],"Radiotherapy-induced Oral Mucositis","2026-03-21",{"date":89,"type":90},"2026-03-25","ACTUAL",{"date":92,"type":80},"2026-03-30",{"date":94,"type":80},"2026-12-30",{"name":5,"class":6},1]