[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100449480":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":28,"locations":38,"responsibleParty":127,"collaborators":129,"id":132,"slug":133,"hasResults":134,"nctId":135,"briefTitle":136,"officialTitle":136,"acronym":137,"eligibilityCriteria":138,"healthyVolunteers":134,"sex":139,"minAge":140,"maxAge":27,"enrollmentInfo":141,"targetDuration":27,"studyType":144,"phases":145,"briefSummary":147,"conditions":148,"keywords":27,"overallStatus":41,"whyStopped":27,"lastUpdateSubmitDate":150,"lastUpdatePostDateStruct":151,"startDateStruct":154,"completionDateStruct":156,"leadSponsor":158,"locationsCount":159},{"fullName":5,"class":6},"University Hospital, Ghent","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"beetroot juice","ACTIVE_COMPARATOR","Brand: BEET IT sport NITRATE 400 concentrated beetroot shot (James White Drinks Ltd.) Dosage regimen: 7 shots of 70 mL, once daily in the morning, on 7 consecutive days before surgery",[13],"Dietary Supplement: concentrated beetroot juice",{"label":15,"type":16,"description":17,"interventionNames":18},"nitrate-depleted beetroot juice","PLACEBO_COMPARATOR","Brand: BEET IT sport NITRATE 400 nitrate-depleted concentrated beetroot shot (James White Drinks Ltd.) Dosage regimen: 7 shots of 70 mL, once daily in the morning, on 7 consecutive days before surgery",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DIETARY_SUPPLEMENT","concentrated beetroot juice","Nitrate supplementation; natural source of dietary nitrate",[9,15],[26],"BEET IT sport NITRATE 400 concentrated beetroot shot",null,[29,35],{"name":30,"role":31,"phone":32,"phoneExt":33,"email":34},"Wim Ceelen, MD, PhD","CONTACT","093326251","+32","wim.ceelen@ugent.be",{"name":36,"role":31,"phone":27,"phoneExt":27,"email":37},"Karen De Meuleneir, MSc","karen.demeuleneir@uzgent.be",[39,59,69,85,95,111],{"facility":40,"status":41,"city":42,"state":27,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Antwerp University Hospital","RECRUITING","Edegem","2650","Belgium","BE",{"type":47,"coordinates":48},"Point",[49,50],4.44504,51.15662,{"lat":50,"lon":49},[53,56],{"name":54,"role":31,"phone":27,"phoneExt":27,"email":55},"Sylvie Van den Broeck, MD","Sylvie.VandenBroeck@uza.be",{"name":57,"role":31,"phone":27,"phoneExt":27,"email":58},"Lieselotte Iket","lieselotte.iket@uza.be",{"facility":60,"status":61,"city":62,"state":27,"zip":63,"country":44,"countryCode":45,"cosmosGeoPoint":64,"geoPoint":68,"contacts":27},"Hospital East-Limburg","ACTIVE_NOT_RECRUITING","Genk","3600",{"type":47,"coordinates":65},[66,67],5.50082,50.965,{"lat":67,"lon":66},{"facility":70,"status":41,"city":71,"state":27,"zip":72,"country":44,"countryCode":45,"cosmosGeoPoint":73,"geoPoint":77,"contacts":78},"AZ Sint-Lucas Ghent","Ghent","9000",{"type":47,"coordinates":74},[75,76],3.71667,51.05,{"lat":76,"lon":75},[79,82],{"name":80,"role":31,"phone":27,"phoneExt":27,"email":81},"Kjell Fierens, MD","kjell.fierens@azsintlucas.be",{"name":83,"role":31,"phone":27,"phoneExt":27,"email":84},"Barbara Vincent","barbara.vincent@azsintlucas.be",{"facility":86,"status":41,"city":71,"state":27,"zip":72,"country":44,"countryCode":45,"cosmosGeoPoint":87,"geoPoint":89,"contacts":90},"Ghent University Hospital",{"type":47,"coordinates":88},[75,76],{"lat":76,"lon":75},[91,92],{"name":36,"role":31,"phone":27,"phoneExt":27,"email":37},{"name":93,"role":31,"phone":27,"phoneExt":27,"email":94},"Sarah Cosyns, PhD","sarah.cosyns@ugent.be",{"facility":96,"status":41,"city":97,"state":27,"zip":98,"country":44,"countryCode":45,"cosmosGeoPoint":99,"geoPoint":103,"contacts":104},"University Hospital Leuven","Leuven","3000",{"type":47,"coordinates":100},[101,102],4.70093,50.87959,{"lat":102,"lon":101},[105,108],{"name":106,"role":31,"phone":27,"phoneExt":27,"email":107},"Albert Wolthuis, MD, PhD","albert.wolthuis@uzleuven.be",{"name":109,"role":31,"phone":27,"phoneExt":27,"email":110},"Isabelle Terrasson","isabelle.terrasson@uzleuven.be",{"facility":112,"status":41,"city":113,"state":27,"zip":114,"country":44,"countryCode":45,"cosmosGeoPoint":115,"geoPoint":119,"contacts":120},"VITAZ","Sint-Niklaas","9100",{"type":47,"coordinates":116},[117,118],4.1437,51.16509,{"lat":118,"lon":117},[121,124],{"name":122,"role":31,"phone":27,"phoneExt":27,"email":123},"Ignace De Keukelaere, MD","Ignace.DeKeukelaere@vitaz.be",{"name":125,"role":31,"phone":27,"phoneExt":27,"email":126},"Lise Vermeir, MSc","Lise.Vermeir@vitaz.be",{"type":128,"investigatorFullName":27,"investigatorTitle":27,"investigatorAffiliation":27,"oldNameTitle":27,"oldOrganization":27},"SPONSOR",[130],{"name":131,"class":6},"Research Foundation Flanders","100449480","phase-2-use-of-beetroot-juice-to-protect-against-postoperative-ileus-following-colorectal-surgery-beet-it-study-100449480",false,"NCT05133024","Use of Beetroot Juice to Protect Against Postoperative Ileus Following Colorectal Surgery: BEET IT Study","BEET IT","Inclusion Criteria:\n\n* Adult patients undergoing elective colonic and upper rectum laparoscopic surgery requiring an anastomosis, without the need of conversion\n\nExclusion Criteria:\n\nGeneral:\n\n* \\\u003C 18 years of age\n* Pregnancy or breast feeding\n\nMedical:\n\n* Psychiatric pathology capable of affecting comprehension and judgment faculty\n* History of inflammatory bowel disease\n* Chronic vascular disease affecting the intestines\n* Chronic constipation (\\\u003C= 2 bowel movements\u002Fweek)\n* Previous abdominal or pelvic radiation treatment\n* Recent (\\\u003C 3 months before inclusion) or current intra-abdominal infection or inflammation (e.g. diverticulitis, appendicitis, cholecystitis)\n* Use of gut motility influencing agents (e.g. tricyclic antidepressants, chronic use of laxatives)\n* Use of nitrates (e.g. isosorbide dinitrate, nitroglycerin), including daily consumption of beetroot juice (unless stopped for a month prior to the intervention period)\n* Hypotension (\\\u003C 100\u002F60 mmHg)\n* Uncontrolled diabetes mellitus\n* Renal or hepatic insufficiency\n* Known allergies or intolerances to beetroot, nitrates\u002Fnitrites\n* Enrollment in other clinical trials\u002Fexperiments, unless approved by the Ethics Committee(s)\n\nSurgical:\n\n* History of prior colorectal surgery\n* Emergency surgery\n* Open surgery\n* Colorectal surgery not requiring an anastomosis (e.g. colotomy, wedge resection)\n* More than 1 bowel anastomosis planned\n* Concomitant surgical procedures required (e.g. resection of liver or lung metastases)\n* Protective stoma planned","ALL","18 Years",{"count":142,"type":143},170,"ESTIMATED","INTERVENTIONAL",[146],"PHASE2","The goal of the BEET IT study is to examine if preoperative intake of beetroot juice can ameliorate gastrointestinal (GI) recovery after colorectal surgery and thereby help to reduce the duration of postoperative ileus (POI) and prevent prolonged POI. Adult patients undergoing laparoscopic colorectal surgery are randomized 1:1 to consume either concentrated beetroot juice (active intervention) or nitrate-depleted concentrated beetroot juice (placebo) during the week before their surgery. Blood, tissue and\u002For fecal samples are collected at specific time points pre- and\u002For postoperatively to study markers related to inflammation, oxidative stress and GI function. Patients are followed from the week before surgery (start of the intervention) until 3 months post-surgery. The study takes place at 5 hospitals in Flanders, Belgium.",[149],"Postoperative Ileus","2026-02-06",{"date":152,"type":153},"2026-02-10","ACTUAL",{"date":155,"type":153},"2021-03-31",{"date":157,"type":143},"2027-12-30",{"name":5,"class":6},6]