[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100409401":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":44,"responsibleParty":61,"collaborators":25,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":25,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":25,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":47,"whyStopped":25,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"University Hospital Schleswig-Holstein","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"motor training","EXPERIMENTAL","intervention: motor training",[13],"Behavioral: motor training",{"label":15,"type":16,"description":17,"interventionNames":18},"awareness training","ACTIVE_COMPARATOR","intervention: mindfulness exercises",[19],"Behavioral: mindfulness exercises",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","In the sensorimotor training program task-specific and non-task specific aspects will be combined. It will start with assignments to improve general finger and wrist movements. After four weeks more specific writing exercises will be added.",[9],null,{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"mindfulness exercises","The awareness training will contain mindfulness exercises. The goal is to consciously experience the here and now in sensual perception of oneself and the environment.",[15],[31],{"name":32,"affiliation":33,"role":34},"Kirsten E Zeuner, Prof. MD","University of Kiel","PRINCIPAL_INVESTIGATOR",[36,41],{"name":32,"role":37,"phone":38,"phoneExt":39,"email":40},"CONTACT","0431-500-23801","0049","k.zeuner@neurologie.uni-kiel.de",{"name":42,"role":37,"phone":38,"phoneExt":39,"email":43},"Arne Knutzen, M.Sc. OT","a.knutzen@neurologie.uni-kiel.de",[45],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"Kiel University","RECRUITING","Kiel","Schleswig-Holstein","24105","Germany","DE",{"type":54,"coordinates":55},"Point",[56,57],10.13489,54.32133,{"lat":57,"lon":56},[60],{"name":32,"role":37,"phone":38,"phoneExt":39,"email":40},{"type":62,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100409401","phase-2-video-supervised-motor-and-awareness-training-in-writers-cramp-100409401",false,"NCT04611009","Video-supervised Motor and Awareness Training in Writer's Cramp","Treatment Effect and Relevance on Daily Life of a Video-supervised Sensorimotor Training Program and Its Influence on the Pathophysiology in Writer's Cramp","Inclusion Criteria:\n\n* Right handed idiopathic WC according to standardized criteria (simple and complex WC, any dystonic posture (including flexion, extension, pronation, supination))\n* able to participate in video-calls\n\nExclusion Criteria:\n\n* Additional neurological or psychiatric diseases\n* left-handed patients\n* last botulinum toxin treatment \\\u003C3 months, remaining weakness from the last injection\n* concomitant use of anticholinergics or sedating medication\n\nExclusion criteria for MRI:\n\n* Cardiac pacemaker, electronic or metal implants\n* pregnancy or suspected pregnancy\n* severe ametropia, anxiety in small rooms","ALL","18 Years","80 Years",{"count":74,"type":75},54,"ESTIMATED","INTERVENTIONAL",[78],"PHASE2","Writer's cramp is the most common task-specific dystonia. It is characterized by involuntary co-contraction of antagonistic muscles during writing. This disabling condition may force patients to give up their occupation. In this study the efficacy of a twelve months long-term training in patients with writer's cramp will be investigated. Two different programs will be offered: The first one will consist of a sensorimotor, the second one of an awareness training. All patients will benefit from video-based supervision with the aim to establish a practice-oriented therapeutic approach that will be available to all patients independently of their home location. The treatment effect will be measured primary with the patient-centered Canadian Occupational Performance Measure (COPM) and secondary with clinical scales to assess the clinical efficacy and everyday constraints. Writing will be assessed with a computer-based kinematic writing analysis. To evaluate the influence on the brain network, several functional magnetic resonance imaging (fMRI) evaluations will be performed. This project is of minimal risk without negative side effects from the training. The risks for the MRI experiment are equal to a non-contrast standard MRI investigation.",[81],"Writer's Cramp",[83,84,85,86,87],"dystonia","training","kinematic writing analysis","COPM","functional magnetic resonance imaging","2024-12-09",{"date":90,"type":91},"2024-12-10","ACTUAL",{"date":93,"type":91},"2020-06-26",{"date":95,"type":75},"2027-01-01",{"name":5,"class":6},1]