[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100588034":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":11,"centralContacts":23,"locations":29,"responsibleParty":44,"collaborators":11,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":11,"eligibilityCriteria":51,"healthyVolunteers":48,"sex":52,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":11,"studyType":58,"phases":59,"briefSummary":61,"conditions":62,"keywords":11,"overallStatus":32,"whyStopped":11,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":69,"leadSponsor":71,"locationsCount":72},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Probiotic supplementation (Lacteol fort 10 billion) which contains culture medium and lactobacillus","EXPERIMENTAL",null,[13],"Drug: lactobacillus LS",{"label":15,"type":16,"description":11,"interventionNames":11},"Participants will be advised to be adherent to their standard treatment and followed up regularly.","NO_INTERVENTION",[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":11},"DRUG","lactobacillus LS","Probiotic supplementation (Lacteol fort 10 billion) which contains culture medium and lactobacillus LS as active ingredients",[9],[24],{"name":25,"role":26,"phone":27,"phoneExt":11,"email":28},"Rehab Abdelmaksoud","CONTACT","02 01158336110","rehab.abdelmaksoud@med.asu.edu.eg",[30],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":11},"AinShams university hospitals","RECRUITING","Cairo","Abbassia","00202","Egypt","EG",{"type":39,"coordinates":40},"Point",[41,42],31.24967,30.06263,{"lat":42,"lon":41},{"type":45,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100588034","phase-3--effect-of-probiotic-supplementation-on-atypical-antipsychotic-induced-weight-gain-in-patients-attending-psychiatric-clinics-at-ainshams-university-hospitals-a-randomized-controlled-trial-100588034",false,"NCT06936137",": EFFECT OF PROBIOTIC SUPPLEMENTATION ON ATYPICAL ANTIPSYCHOTIC INDUCED WEIGHT GAIN IN PATIENTS ATTENDING PSYCHIATRIC CLINICS AT AINSHAMS UNIVERSITY HOSPITALS (A RANDOMIZED CONTROLLED TRIAL)","Inclusion Criteria:\n\n* Adult schizophrenia patients (18-45 years) on second generation antipsychotics Stable patients with a total positive and negative syndrome scale (PANSS) score of ≤60.\n\nWith more than 10% weight gain after taking atypical antipsychotics for at least 3 months with treatment duration not more than two years.\n\nExclusion Criteria:\n\n1. Taking probiotics, fiber supplements, antibiotics and laxatives in the last 6 weeks.\n2. Comorbid gastrointestinal diseases, including active peptic ulcer, uncontrolled and recurrent diarrhea, gastrointestinal bleeding, and digestive system neoplastic diseases.\n\n   \\-","ALL","18 Years","45 Years",{"count":56,"type":57},180,"ESTIMATED","INTERVENTIONAL",[60],"PHASE3","the goal of the study is to improve the quality of life of patients on antipsychotic medications and increase the rate of compliance to treatment.\n\nPrimary objective:\n\n1.To determine the effectiveness of probiotics to decrease the weight gained as a result of antipsychotic medications.\n\nSecondary objective:\n\n1\\. To determine the effect of probiotic supplementation on the psychological state of patients.",[63],"Antipsychotic Induced Weight Gain","2025-04-18",{"date":66,"type":67},"2025-04-20","ACTUAL",{"date":66,"type":57},{"date":70,"type":57},"2026-12-20",{"name":5,"class":6},1]