[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100596349":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":41,"centralContacts":45,"locations":51,"responsibleParty":956,"collaborators":27,"id":958,"slug":959,"hasResults":960,"nctId":961,"briefTitle":962,"officialTitle":963,"acronym":27,"eligibilityCriteria":964,"healthyVolunteers":965,"sex":966,"minAge":967,"maxAge":27,"enrollmentInfo":968,"targetDuration":27,"studyType":971,"phases":972,"briefSummary":974,"conditions":975,"keywords":27,"overallStatus":54,"whyStopped":27,"lastUpdateSubmitDate":978,"lastUpdatePostDateStruct":979,"startDateStruct":982,"completionDateStruct":984,"leadSponsor":986,"locationsCount":987},{"fullName":5,"class":6},"Merck Sharp & Dohme LLC","INDUSTRY",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"MK-8527","EXPERIMENTAL","Participants will receive 11 mg MK-8527 once monthly (QM) and placebo to FTC\u002FTDF once daily (QD) for up to approximately 2 years. Participants will then receive open-label 200 mg FTC\u002F245 mg TDF QD for an additional 28 days.",[13,14,15],"Drug: MK-8527","Drug: FTC\u002FTDF","Drug: Placebo to FTC\u002FTDF",{"label":17,"type":18,"description":19,"interventionNames":20},"FTC\u002FTDF","ACTIVE_COMPARATOR","Participants will receive 200 mg FTC\u002F245 mg TDF QD and placebo to MK-8527 QM for up to approximately 2 years. Participants will then receive open-label 200 mg FTC\u002F245 mg TDF QD for an additional 28 days.",[14,21],"Drug: Placebo to MK-8527",[23,28,33,37],{"type":24,"name":9,"description":25,"armGroupLabels":26,"otherNames":27},"DRUG","Oral tablet",[9],null,{"type":24,"name":17,"description":25,"armGroupLabels":29,"otherNames":30},[17,9],[31,32],"Truvada","Emtricitabine\u002FTenofovir Disoproxil Fumarate",{"type":24,"name":34,"description":35,"armGroupLabels":36,"otherNames":27},"Placebo to MK-8527","Placebo tablet matched to MK-8527",[17],{"type":24,"name":38,"description":39,"armGroupLabels":40,"otherNames":27},"Placebo to FTC\u002FTDF","Placebo tablet matched to FTC\u002FTDF",[9],[42],{"name":43,"affiliation":5,"role":44},"Medical Director","STUDY_DIRECTOR",[46],{"name":47,"role":48,"phone":49,"phoneExt":27,"email":50},"Toll Free Number","CONTACT","1-888-577-8839","Trialsites@msd.com",[52,70,82,95,107,120,133,145,158,171,184,197,210,223,236,248,261,273,286,299,311,324,336,349,359,363,369,378,389,404,417,430,443,455,464,473,484,499,512,521,536,549,559,572,587,596,604,615,621,628,642,650,659,674,686,695,709,721,730,736,742,748,754,766,775,779,789,802,814,826,839,852,867,880,892,906,914,922,928,936,947],{"facility":53,"status":54,"city":55,"state":56,"zip":57,"country":58,"countryCode":59,"cosmosGeoPoint":60,"geoPoint":65,"contacts":66},"University of Alabama at Birmingham-UAB 1917 Research Clinic ( Site 0006)","RECRUITING","Birmingham","Alabama","35222","United States","US",{"type":61,"coordinates":62},"Point",[63,64],-86.80249,33.52066,{"lat":64,"lon":63},[67],{"name":68,"role":48,"phone":69,"phoneExt":27,"email":27},"Study Coordinator","205-934-2490",{"facility":71,"status":54,"city":72,"state":56,"zip":73,"country":58,"countryCode":59,"cosmosGeoPoint":74,"geoPoint":78,"contacts":79},"USA Health University Hospitals ( Site 0020)","Mobile","36617",{"type":61,"coordinates":75},[76,77],-88.04305,30.69436,{"lat":77,"lon":76},[80],{"name":68,"role":48,"phone":81,"phoneExt":27,"email":27},"251-471-7000",{"facility":83,"status":54,"city":84,"state":85,"zip":86,"country":58,"countryCode":59,"cosmosGeoPoint":87,"geoPoint":91,"contacts":92},"UCLA Center for Clinical AIDS Research and Education ( Site 0004)","Los Angeles","California","90035",{"type":61,"coordinates":88},[89,90],-118.24368,34.05223,{"lat":90,"lon":89},[93],{"name":68,"role":48,"phone":94,"phoneExt":27,"email":27},"310-843-2015",{"facility":96,"status":54,"city":97,"state":85,"zip":98,"country":58,"countryCode":59,"cosmosGeoPoint":99,"geoPoint":103,"contacts":104},"Bridge HIV - San Francisco Department of Public Health ( Site 0001)","San Francisco","94102",{"type":61,"coordinates":100},[101,102],-122.41942,37.77493,{"lat":102,"lon":101},[105],{"name":68,"role":48,"phone":106,"phoneExt":27,"email":27},"628-217-7400",{"facility":108,"status":54,"city":109,"state":110,"zip":111,"country":58,"countryCode":59,"cosmosGeoPoint":112,"geoPoint":116,"contacts":117},"Whitman-Walker Institute ( Site 0016)","Washington D.C.","District of Columbia","20032",{"type":61,"coordinates":113},[114,115],-77.03637,38.89511,{"lat":115,"lon":114},[118],{"name":68,"role":48,"phone":119,"phoneExt":27,"email":27},"202-207-2510",{"facility":121,"status":54,"city":122,"state":123,"zip":124,"country":58,"countryCode":59,"cosmosGeoPoint":125,"geoPoint":129,"contacts":130},"University of Miami RAPID Research ( Site 0003)","Miami","Florida","33136",{"type":61,"coordinates":126},[127,128],-80.19366,25.77427,{"lat":128,"lon":127},[131],{"name":68,"role":48,"phone":132,"phoneExt":27,"email":27},"305-243-4378",{"facility":134,"status":54,"city":135,"state":123,"zip":136,"country":58,"countryCode":59,"cosmosGeoPoint":137,"geoPoint":141,"contacts":142},"Orlando Immunology Center ( Site 0021)","Orlando","32803",{"type":61,"coordinates":138},[139,140],-81.37924,28.53834,{"lat":140,"lon":139},[143],{"name":68,"role":48,"phone":144,"phoneExt":27,"email":27},"407-374-0220",{"facility":146,"status":54,"city":147,"state":148,"zip":149,"country":58,"countryCode":59,"cosmosGeoPoint":150,"geoPoint":154,"contacts":155},"Hope Clinic of the Emory Vaccine Center ( Site 0009)","Decatur","Georgia","30030",{"type":61,"coordinates":151},[152,153],-84.29631,33.77483,{"lat":153,"lon":152},[156],{"name":68,"role":48,"phone":157,"phoneExt":27,"email":27},"404-712-1370",{"facility":159,"status":54,"city":160,"state":161,"zip":162,"country":58,"countryCode":59,"cosmosGeoPoint":163,"geoPoint":167,"contacts":168},"University of Illinois Chicago ( Site 0027)","Chicago","Illinois","60612",{"type":61,"coordinates":164},[165,166],-87.65005,41.85003,{"lat":166,"lon":165},[169],{"name":68,"role":48,"phone":170,"phoneExt":27,"email":27},"312-864-4578",{"facility":172,"status":54,"city":173,"state":174,"zip":175,"country":58,"countryCode":59,"cosmosGeoPoint":176,"geoPoint":180,"contacts":181},"University Medical Center New Orleans ( Site 0024)","New Orleans","Louisiana","70112",{"type":61,"coordinates":177},[178,179],-90.07507,29.95465,{"lat":179,"lon":178},[182],{"name":68,"role":48,"phone":183,"phoneExt":27,"email":27},"504-568-7740",{"facility":185,"status":54,"city":186,"state":187,"zip":188,"country":58,"countryCode":59,"cosmosGeoPoint":189,"geoPoint":193,"contacts":194},"Open Arms Healthcare Center ( Site 0025)","Jackson","Mississippi","39202",{"type":61,"coordinates":190},[191,192],-90.18481,32.29876,{"lat":192,"lon":191},[195],{"name":68,"role":48,"phone":196,"phoneExt":27,"email":27},"601-500-7660",{"facility":198,"status":54,"city":199,"state":200,"zip":201,"country":58,"countryCode":59,"cosmosGeoPoint":202,"geoPoint":206,"contacts":207},"Rutgers New Jersey Medical School ( Site 0010)","Newark","New Jersey","07103",{"type":61,"coordinates":203},[204,205],-74.17237,40.73566,{"lat":205,"lon":204},[208],{"name":68,"role":48,"phone":209,"phoneExt":27,"email":27},"848-445-4357",{"facility":211,"status":54,"city":212,"state":213,"zip":214,"country":58,"countryCode":59,"cosmosGeoPoint":215,"geoPoint":219,"contacts":220},"Montefiore Medical Center ( Site 0017)","The Bronx","New York","10467",{"type":61,"coordinates":216},[217,218],-73.86641,40.84985,{"lat":218,"lon":217},[221],{"name":68,"role":48,"phone":222,"phoneExt":27,"email":27},"718-920-2229",{"facility":224,"status":54,"city":225,"state":226,"zip":227,"country":58,"countryCode":59,"cosmosGeoPoint":228,"geoPoint":232,"contacts":233},"NC TraCS Institute - CTRC; University of North Carolina at Chapel Hill ( Site 0008)","Chapel Hill","North Carolina","27514-7064",{"type":61,"coordinates":229},[230,231],-79.05584,35.9132,{"lat":231,"lon":230},[234],{"name":68,"role":48,"phone":235,"phoneExt":27,"email":27},"919-843-0720",{"facility":237,"status":54,"city":238,"state":226,"zip":239,"country":58,"countryCode":59,"cosmosGeoPoint":240,"geoPoint":244,"contacts":245},"Regional Center for Infectious Diseases ( Site 0018)","Greensboro","27401",{"type":61,"coordinates":241},[242,243],-79.79198,36.07264,{"lat":243,"lon":242},[246],{"name":68,"role":48,"phone":247,"phoneExt":27,"email":27},"336-832-3275",{"facility":249,"status":54,"city":250,"state":251,"zip":252,"country":58,"countryCode":59,"cosmosGeoPoint":253,"geoPoint":257,"contacts":258},"Philadelphia Fight Community Health Centers ( Site 0011)","Philadelphia","Pennsylvania","19107",{"type":61,"coordinates":254},[255,256],-75.16362,39.95238,{"lat":256,"lon":255},[259],{"name":68,"role":48,"phone":260,"phoneExt":27,"email":27},"214-985-4448",{"facility":262,"status":54,"city":263,"state":251,"zip":264,"country":58,"countryCode":59,"cosmosGeoPoint":265,"geoPoint":269,"contacts":270},"University of Pittsburgh Medical Center-Division of Infectious Diseases ( Site 0022)","Pittsburgh","15213",{"type":61,"coordinates":266},[267,268],-79.99589,40.44062,{"lat":268,"lon":267},[271],{"name":68,"role":48,"phone":272,"phoneExt":27,"email":27},"412-648-9636",{"facility":274,"status":54,"city":275,"state":276,"zip":277,"country":58,"countryCode":59,"cosmosGeoPoint":278,"geoPoint":282,"contacts":283},"Prisma Health Richland Hospital-Clinical Research Unit ( Site 0007)","Columbia","South Carolina","29203",{"type":61,"coordinates":279},[280,281],-81.03481,34.00071,{"lat":281,"lon":280},[284],{"name":68,"role":48,"phone":285,"phoneExt":27,"email":27},"803-434-7703",{"facility":287,"status":54,"city":288,"state":289,"zip":290,"country":58,"countryCode":59,"cosmosGeoPoint":291,"geoPoint":295,"contacts":296},"St. Jude Children's Research Hospital ( Site 0026)","Memphis","Tennessee","38105",{"type":61,"coordinates":292},[293,294],-90.04898,35.14953,{"lat":294,"lon":293},[297],{"name":68,"role":48,"phone":298,"phoneExt":27,"email":27},"901-595-3300",{"facility":300,"status":54,"city":301,"state":289,"zip":302,"country":58,"countryCode":59,"cosmosGeoPoint":303,"geoPoint":307,"contacts":308},"Meharry Medical College ( Site 0013)","Nashville","37208",{"type":61,"coordinates":304},[305,306],-86.78444,36.16589,{"lat":306,"lon":305},[309],{"name":68,"role":48,"phone":310,"phoneExt":27,"email":27},"615-327-6353",{"facility":312,"status":54,"city":313,"state":314,"zip":315,"country":58,"countryCode":59,"cosmosGeoPoint":316,"geoPoint":320,"contacts":321},"Central Texas Clinical Research ( Site 0014)","Austin","Texas","78705",{"type":61,"coordinates":317},[318,319],-97.74306,30.26715,{"lat":319,"lon":318},[322],{"name":68,"role":48,"phone":323,"phoneExt":27,"email":27},"512-496-9899",{"facility":325,"status":54,"city":326,"state":314,"zip":327,"country":58,"countryCode":59,"cosmosGeoPoint":328,"geoPoint":332,"contacts":333},"Saint Hope Foundation, Inc. ( Site 0015)","Bellaire","77401",{"type":61,"coordinates":329},[330,331],-95.45883,29.70579,{"lat":331,"lon":330},[334],{"name":68,"role":48,"phone":335,"phoneExt":27,"email":27},"713-839-7111",{"facility":337,"status":54,"city":338,"state":339,"zip":340,"country":58,"countryCode":59,"cosmosGeoPoint":341,"geoPoint":345,"contacts":346},"Fred Hutchinson Cancer Center - The Seattle HIV Vaccine Trials Unit ( Site 0002)","Seattle","Washington","98104",{"type":61,"coordinates":342},[343,344],-122.33207,47.60621,{"lat":344,"lon":343},[347],{"name":68,"role":48,"phone":348,"phoneExt":27,"email":27},"206-667-2300",{"facility":350,"status":54,"city":351,"state":352,"zip":353,"country":354,"countryCode":355,"cosmosGeoPoint":27,"geoPoint":27,"contacts":356},"Centro de Estudios Infectológicos S.A. ( Site 0357)","CABA","Buenos Aires","C1002ABN","Argentina","AR",[357],{"name":68,"role":48,"phone":358,"phoneExt":27,"email":27},"+5402920323936",{"facility":360,"status":361,"city":351,"state":352,"zip":362,"country":354,"countryCode":355,"cosmosGeoPoint":27,"geoPoint":27,"contacts":27},"Centro Medico Dra. Laura Maffei- Investigacion Clinica Aplicada ( Site 0352)","ACTIVE_NOT_RECRUITING","C1425AGC",{"facility":364,"status":54,"city":351,"state":352,"zip":365,"country":354,"countryCode":355,"cosmosGeoPoint":27,"geoPoint":27,"contacts":366},"Fundación Huésped ( Site 0350)","C1427CEA",[367],{"name":68,"role":48,"phone":368,"phoneExt":27,"email":27},"+541121209999",{"facility":370,"status":361,"city":371,"state":352,"zip":372,"country":354,"countryCode":355,"cosmosGeoPoint":373,"geoPoint":377,"contacts":27},"Instituto de Investigaciones Clínicas Mar del Plata ( Site 0353)","Mar del Plata","B7600FZO",{"type":61,"coordinates":374},[375,376],-57.5562,-38.00042,{"lat":376,"lon":375},{"facility":379,"status":54,"city":352,"state":27,"zip":380,"country":354,"countryCode":355,"cosmosGeoPoint":381,"geoPoint":385,"contacts":386},"Fundación IDEAA ( Site 0351)","C1405CKC",{"type":61,"coordinates":382},[383,384],-58.37723,-34.61315,{"lat":384,"lon":383},[387],{"name":68,"role":48,"phone":388,"phoneExt":27,"email":27},"+541149040623",{"facility":390,"status":54,"city":391,"state":392,"zip":393,"country":394,"countryCode":395,"cosmosGeoPoint":396,"geoPoint":400,"contacts":401},"Fundaçao de Medicina Tropical Doutor Heitor Vieira Dourado ( Site 0412)","Manaus","Amazonas","69040-000","Brazil","BR",{"type":61,"coordinates":397},[398,399],-60.025,-3.10194,{"lat":399,"lon":398},[402],{"name":68,"role":48,"phone":403,"phoneExt":27,"email":27},"+559221273589",{"facility":405,"status":54,"city":406,"state":407,"zip":408,"country":394,"countryCode":395,"cosmosGeoPoint":409,"geoPoint":413,"contacts":414},"Obras Sociais Irma Dulce ( Site 0406)","Salvador","Estado de Bahia","41680-430",{"type":61,"coordinates":410},[411,412],-38.49096,-12.97563,{"lat":412,"lon":411},[415],{"name":68,"role":48,"phone":416,"phoneExt":27,"email":27},"+55 (71) 3483-6649",{"facility":418,"status":54,"city":419,"state":420,"zip":421,"country":394,"countryCode":395,"cosmosGeoPoint":422,"geoPoint":426,"contacts":427},"School of Medicine Federal University of Minas Gerais ( Site 0417)","Belo Horizonte","Minas Gerais","30130-100",{"type":61,"coordinates":423},[424,425],-43.93778,-19.92083,{"lat":425,"lon":424},[428],{"name":68,"role":48,"phone":429,"phoneExt":27,"email":27},"+5531984546856",{"facility":431,"status":54,"city":432,"state":433,"zip":434,"country":394,"countryCode":395,"cosmosGeoPoint":435,"geoPoint":439,"contacts":440},"Hospital Geral de Nova Iguacu ( Site 0411)","Nova Iguaçu","Rio de Janeiro","26030-380",{"type":61,"coordinates":436},[437,438],-43.45111,-22.75917,{"lat":438,"lon":437},[441],{"name":68,"role":48,"phone":442,"phoneExt":27,"email":27},"+552137799900",{"facility":444,"status":54,"city":445,"state":445,"zip":446,"country":394,"countryCode":395,"cosmosGeoPoint":447,"geoPoint":451,"contacts":452},"Ricardo Diaz Scientific Solutions ( Site 0402)","São Paulo","04030-030",{"type":61,"coordinates":448},[449,450],-46.63611,-23.5475,{"lat":450,"lon":449},[453],{"name":68,"role":48,"phone":454,"phoneExt":27,"email":27},"+5521997994412",{"facility":456,"status":54,"city":445,"state":445,"zip":457,"country":394,"countryCode":395,"cosmosGeoPoint":458,"geoPoint":460,"contacts":461},"Centro de Referência e Treinamento DST\u002FAIDS ( Site 0400)","04121-000",{"type":61,"coordinates":459},[449,450],{"lat":450,"lon":449},[462],{"name":68,"role":48,"phone":463,"phoneExt":27,"email":27},"+551150879903",{"facility":465,"status":54,"city":445,"state":445,"zip":466,"country":394,"countryCode":395,"cosmosGeoPoint":467,"geoPoint":469,"contacts":470},"Hospital das Clinicas FMUSP ( Site 0401)","05403-000",{"type":61,"coordinates":468},[449,450],{"lat":450,"lon":449},[471],{"name":68,"role":48,"phone":472,"phoneExt":27,"email":27},"+5511976621295",{"facility":474,"status":54,"city":433,"state":27,"zip":475,"country":394,"countryCode":395,"cosmosGeoPoint":476,"geoPoint":480,"contacts":481},"Instituto Nacional de Infectologia Evandro Chagas ( Site 0407)","21040-360",{"type":61,"coordinates":477},[478,479],-43.18223,-22.90642,{"lat":479,"lon":478},[482],{"name":68,"role":48,"phone":483,"phoneExt":27,"email":27},"+552138659595",{"facility":485,"status":54,"city":486,"state":487,"zip":488,"country":489,"countryCode":490,"cosmosGeoPoint":491,"geoPoint":495,"contacts":496},"Hospital Dr. Hernán Henríquez Aravena ( Site 0451)","Temuco","Araucania","4781151","Chile","CL",{"type":61,"coordinates":492},[493,494],-72.59738,-38.73628,{"lat":494,"lon":493},[497],{"name":68,"role":48,"phone":498,"phoneExt":27,"email":27},"+56452556875",{"facility":500,"status":54,"city":501,"state":502,"zip":503,"country":489,"countryCode":490,"cosmosGeoPoint":504,"geoPoint":508,"contacts":509},"Universidad San Sebastian - Providencia ( Site 0454)","Santiago","Region M. de Santiago","7500000",{"type":61,"coordinates":505},[506,507],-70.64827,-33.45694,{"lat":507,"lon":506},[510],{"name":68,"role":48,"phone":511,"phoneExt":27,"email":27},"+56222606755",{"facility":513,"status":54,"city":501,"state":502,"zip":514,"country":489,"countryCode":490,"cosmosGeoPoint":515,"geoPoint":517,"contacts":518},"Universidad de Chile - Hospital Clínico Universidad de Chile-Inmunologia Alergia y VIH ( Site 0450)","8380420",{"type":61,"coordinates":516},[506,507],{"lat":507,"lon":506},[519],{"name":68,"role":48,"phone":520,"phoneExt":27,"email":27},"+56992280653",{"facility":522,"status":54,"city":523,"state":524,"zip":525,"country":526,"countryCode":527,"cosmosGeoPoint":528,"geoPoint":532,"contacts":533},"IPS SURA San Diego ( Site 0500)","Medellín","Antioquia","50016","Colombia","CO",{"type":61,"coordinates":529},[530,531],-75.57151,6.245,{"lat":531,"lon":530},[534],{"name":68,"role":48,"phone":535,"phoneExt":27,"email":27},"+57311728461",{"facility":537,"status":54,"city":538,"state":539,"zip":540,"country":526,"countryCode":527,"cosmosGeoPoint":541,"geoPoint":545,"contacts":546},"Clinica de la Costa S.A.S. ( Site 0501)","Barranquilla","Atlántico","080020",{"type":61,"coordinates":542},[543,544],-74.78132,10.96854,{"lat":544,"lon":543},[547],{"name":68,"role":48,"phone":548,"phoneExt":27,"email":27},"+57 3128335766",{"facility":550,"status":361,"city":551,"state":552,"zip":553,"country":526,"countryCode":527,"cosmosGeoPoint":554,"geoPoint":558,"contacts":27},"Hospital Universitario San Ignacio ( Site 0503)","Bogotá","Bogota D.C.","110231",{"type":61,"coordinates":555},[556,557],-74.08175,4.60971,{"lat":557,"lon":556},{"facility":560,"status":54,"city":561,"state":562,"zip":563,"country":526,"countryCode":527,"cosmosGeoPoint":564,"geoPoint":568,"contacts":569},"Fundación Valle del Lili ( Site 0502)","Cali","Valle del Cauca Department","760032",{"type":61,"coordinates":565},[566,567],-76.5199,3.43054,{"lat":567,"lon":566},[570],{"name":68,"role":48,"phone":571,"phoneExt":27,"email":27},"3164038861",{"facility":573,"status":54,"city":574,"state":575,"zip":576,"country":577,"countryCode":578,"cosmosGeoPoint":579,"geoPoint":583,"contacts":584},"CEMDOE - Centro Médico de Diabetes, Obesidad y Especialidades ( Site 1001)","Santo Domingo","Nacional","10104","Dominican Republic","DO",{"type":61,"coordinates":580},[581,582],-69.89232,18.47186,{"lat":582,"lon":581},[585],{"name":68,"role":48,"phone":586,"phoneExt":27,"email":27},"+8097410000",{"facility":588,"status":54,"city":574,"state":575,"zip":589,"country":577,"countryCode":578,"cosmosGeoPoint":590,"geoPoint":592,"contacts":593},"Endocardio ( Site 1003)","10147",{"type":61,"coordinates":591},[581,582],{"lat":582,"lon":581},[594],{"name":68,"role":48,"phone":595,"phoneExt":27,"email":27},"+8093642270",{"facility":597,"status":54,"city":598,"state":599,"zip":600,"country":577,"countryCode":578,"cosmosGeoPoint":27,"geoPoint":27,"contacts":601},"Instituto Dermatológico y Cirugía de Piel \"Dr. Huberto Bogaert Díaz\" ( Site 1002)","Santo Domingo de Guzman","Santo Domingo Province","10306",[602],{"name":68,"role":48,"phone":603,"phoneExt":27,"email":27},"+8093428925",{"facility":605,"status":361,"city":606,"state":27,"zip":607,"country":608,"countryCode":609,"cosmosGeoPoint":610,"geoPoint":614,"contacts":27},"Hopital Saint Louis ( Site 0100)","Paris","75010","France","FR",{"type":61,"coordinates":611},[612,613],2.3488,48.85341,{"lat":613,"lon":612},{"facility":616,"status":361,"city":606,"state":27,"zip":617,"country":608,"countryCode":609,"cosmosGeoPoint":618,"geoPoint":620,"contacts":27},"Hôpital Tenon ( Site 0102)","75970",{"type":61,"coordinates":619},[612,613],{"lat":613,"lon":612},{"facility":622,"status":361,"city":606,"state":623,"zip":624,"country":608,"countryCode":609,"cosmosGeoPoint":625,"geoPoint":627,"contacts":27},"Hopital Bichat - Claude Bernard ( Site 0101)","Île-de-France Region","75018",{"type":61,"coordinates":626},[612,613],{"lat":613,"lon":612},{"facility":629,"status":54,"city":630,"state":27,"zip":631,"country":632,"countryCode":633,"cosmosGeoPoint":634,"geoPoint":638,"contacts":639},"Clínica Médica Especializada en Pediatría e Infectología Pediátrica - Dr. Mario Melgar ( Site 1051)","Guatemala City","01009","Guatemala","GT",{"type":61,"coordinates":635},[636,637],-90.51327,14.64072,{"lat":637,"lon":636},[640],{"name":68,"role":48,"phone":641,"phoneExt":27,"email":27},"+50233911230",{"facility":643,"status":54,"city":630,"state":27,"zip":631,"country":632,"countryCode":633,"cosmosGeoPoint":644,"geoPoint":646,"contacts":647},"MEDI-K ( Site 1053)",{"type":61,"coordinates":645},[636,637],{"lat":637,"lon":636},[648],{"name":68,"role":48,"phone":649,"phoneExt":27,"email":27},"+50222912323",{"facility":651,"status":54,"city":630,"state":27,"zip":652,"country":632,"countryCode":633,"cosmosGeoPoint":653,"geoPoint":655,"contacts":656},"CELAN,S.A ( Site 1052)","01010",{"type":61,"coordinates":654},[636,637],{"lat":637,"lon":636},[657],{"name":68,"role":48,"phone":658,"phoneExt":27,"email":27},"+5022912323",{"facility":660,"status":54,"city":661,"state":662,"zip":663,"country":664,"countryCode":665,"cosmosGeoPoint":666,"geoPoint":670,"contacts":671},"Partners for Health and Development in Africa ( Site 0201)","Nairobi","Nairobi City","00506","Kenya","KE",{"type":61,"coordinates":667},[668,669],36.81667,-1.28333,{"lat":669,"lon":668},[672],{"name":68,"role":48,"phone":673,"phoneExt":27,"email":27},"+254733719711",{"facility":675,"status":54,"city":676,"state":27,"zip":677,"country":664,"countryCode":665,"cosmosGeoPoint":678,"geoPoint":682,"contacts":683},"Kargeno Research & Policy Hub ( Site 0200)","Kisumu","40123",{"type":61,"coordinates":679},[680,681],34.76171,-0.10221,{"lat":681,"lon":680},[684],{"name":68,"role":48,"phone":685,"phoneExt":27,"email":27},"+25 474 073 5741",{"facility":687,"status":54,"city":676,"state":27,"zip":688,"country":664,"countryCode":665,"cosmosGeoPoint":689,"geoPoint":691,"contacts":692},"Impact Research and Development Organisation (IRDO) ( Site 0202)","40141",{"type":61,"coordinates":690},[680,681],{"lat":681,"lon":680},[693],{"name":68,"role":48,"phone":694,"phoneExt":27,"email":27},"+254722847249",{"facility":696,"status":54,"city":697,"state":27,"zip":698,"country":699,"countryCode":700,"cosmosGeoPoint":701,"geoPoint":705,"contacts":706},"Universiti Malaya Medical Centre ( Site 0651)","Kuala Lumpur","50603","Malaysia","MY",{"type":61,"coordinates":702},[703,704],101.68653,3.1412,{"lat":704,"lon":703},[707],{"name":68,"role":48,"phone":708,"phoneExt":27,"email":27},"+60379492351",{"facility":710,"status":361,"city":711,"state":712,"zip":713,"country":714,"countryCode":715,"cosmosGeoPoint":716,"geoPoint":720,"contacts":27},"Asociación Civil Selva Amazónica ( Site 0556)","Iquitos","Loreto","16001","Peru","PE",{"type":61,"coordinates":717},[718,719],-73.2529,-3.74814,{"lat":719,"lon":718},{"facility":722,"status":361,"city":723,"state":27,"zip":724,"country":714,"countryCode":715,"cosmosGeoPoint":725,"geoPoint":729,"contacts":27},"Via Libre ( Site 0551)","Lima","15001",{"type":61,"coordinates":726},[727,728],-77.02824,-12.04318,{"lat":728,"lon":727},{"facility":731,"status":361,"city":723,"state":27,"zip":732,"country":714,"countryCode":715,"cosmosGeoPoint":733,"geoPoint":735,"contacts":27},"Policlínico Socios en Salud ( Site 0557)","15024",{"type":61,"coordinates":734},[727,728],{"lat":728,"lon":727},{"facility":737,"status":361,"city":723,"state":27,"zip":738,"country":714,"countryCode":715,"cosmosGeoPoint":739,"geoPoint":741,"contacts":27},"Investigaciones Medicas en Salud ( Site 0552)","15046",{"type":61,"coordinates":740},[727,728],{"lat":728,"lon":727},{"facility":743,"status":361,"city":723,"state":27,"zip":744,"country":714,"countryCode":715,"cosmosGeoPoint":745,"geoPoint":747,"contacts":27},"Asociación Civil Impacta Salud y Educación ( Site 0553)","15063",{"type":61,"coordinates":746},[727,728],{"lat":728,"lon":727},{"facility":749,"status":361,"city":723,"state":27,"zip":750,"country":714,"countryCode":715,"cosmosGeoPoint":751,"geoPoint":753,"contacts":27},"Universidad Nacional Mayor De San Marcos ( Site 0555)","15081",{"type":61,"coordinates":752},[727,728],{"lat":728,"lon":727},{"facility":755,"status":361,"city":756,"state":757,"zip":758,"country":759,"countryCode":760,"cosmosGeoPoint":761,"geoPoint":765,"contacts":27},"LoveYourself Inc. ( Site 0705)","Mandaluyong","National Capital Region","1552","Philippines","PH",{"type":61,"coordinates":762},[763,764],121.0409,14.5832,{"lat":764,"lon":763},{"facility":767,"status":361,"city":768,"state":757,"zip":769,"country":759,"countryCode":760,"cosmosGeoPoint":770,"geoPoint":774,"contacts":27},"Philippine General Hospital ( Site 0700)","Manila","1000",{"type":61,"coordinates":771},[772,773],120.9822,14.6042,{"lat":773,"lon":772},{"facility":776,"status":361,"city":777,"state":757,"zip":778,"country":759,"countryCode":760,"cosmosGeoPoint":27,"geoPoint":27,"contacts":27},"Asian Hospital and Medical Center ( Site 0704)","Muntinlupa","1780",{"facility":780,"status":54,"city":781,"state":782,"zip":783,"country":784,"countryCode":785,"cosmosGeoPoint":27,"geoPoint":27,"contacts":786},"Foundation For Professional Development ( Site 0257)","King Williams Town","Eastern Cape","5660","South Africa","ZA",[787],{"name":68,"role":48,"phone":788,"phoneExt":27,"email":27},"+27672388219",{"facility":790,"status":54,"city":791,"state":792,"zip":793,"country":784,"countryCode":785,"cosmosGeoPoint":794,"geoPoint":798,"contacts":799},"Wits RHI Research Center ( Site 0251)","Johannesburg","Gauteng","2001",{"type":61,"coordinates":795},[796,797],28.04363,-26.20227,{"lat":797,"lon":796},[800],{"name":68,"role":48,"phone":801,"phoneExt":27,"email":27},"011 358 5424",{"facility":803,"status":54,"city":804,"state":792,"zip":805,"country":784,"countryCode":785,"cosmosGeoPoint":806,"geoPoint":810,"contacts":811},"Setshaba Research Centre ( Site 0252)","Pretoria","0152",{"type":61,"coordinates":807},[808,809],28.18783,-25.74486,{"lat":809,"lon":808},[812],{"name":68,"role":48,"phone":813,"phoneExt":27,"email":27},"0127992422",{"facility":815,"status":54,"city":816,"state":792,"zip":817,"country":784,"countryCode":785,"cosmosGeoPoint":818,"geoPoint":822,"contacts":823},"Perinatal HIV Research Unit (PHRU) ( Site 0253)","Soweto","1864",{"type":61,"coordinates":819},[820,821],27.85849,-26.26781,{"lat":821,"lon":820},[824],{"name":68,"role":48,"phone":825,"phoneExt":27,"email":27},"+27 11 989 9711",{"facility":827,"status":54,"city":828,"state":829,"zip":830,"country":784,"countryCode":785,"cosmosGeoPoint":831,"geoPoint":835,"contacts":836},"Wits Maternal Adolescent and Child Health Research Unit (WMRU) ( Site 0256)","Durban","KwaZulu-Natal","4001",{"type":61,"coordinates":832},[833,834],31.0292,-29.8579,{"lat":834,"lon":833},[837],{"name":68,"role":48,"phone":838,"phoneExt":27,"email":27},"031 001 1900",{"facility":840,"status":54,"city":841,"state":842,"zip":843,"country":784,"countryCode":785,"cosmosGeoPoint":844,"geoPoint":848,"contacts":849},"Desmond Tutu Health Foundation ( Site 0250)","Cape Town","Western Cape","7925",{"type":61,"coordinates":845},[846,847],18.42322,-33.92584,{"lat":847,"lon":846},[850],{"name":68,"role":48,"phone":851,"phoneExt":27,"email":27},"+27216501941",{"facility":853,"status":54,"city":854,"state":855,"zip":856,"country":857,"countryCode":858,"cosmosGeoPoint":859,"geoPoint":863,"contacts":864},"University Hospital Basel ( Site 1102)","Basel","Canton of Basel-City","4031","Switzerland","CH",{"type":61,"coordinates":860},[861,862],7.57327,47.55839,{"lat":862,"lon":861},[865],{"name":68,"role":48,"phone":866,"phoneExt":27,"email":27},"+41612652525",{"facility":868,"status":54,"city":869,"state":870,"zip":871,"country":857,"countryCode":858,"cosmosGeoPoint":872,"geoPoint":876,"contacts":877},"Inselspital Bern ( Site 1103)","Bern","Canton of Bern","3010",{"type":61,"coordinates":873},[874,875],7.44744,46.94809,{"lat":875,"lon":874},[878],{"name":68,"role":48,"phone":879,"phoneExt":27,"email":27},"+41316322111",{"facility":881,"status":54,"city":882,"state":27,"zip":883,"country":857,"countryCode":858,"cosmosGeoPoint":884,"geoPoint":888,"contacts":889},"Checkpoint Zurich ( Site 1100)","Zurich","8005",{"type":61,"coordinates":885},[886,887],8.55,47.36667,{"lat":887,"lon":886},[890],{"name":68,"role":48,"phone":891,"phoneExt":27,"email":27},"+41444555910",{"facility":893,"status":54,"city":894,"state":894,"zip":895,"country":896,"countryCode":897,"cosmosGeoPoint":898,"geoPoint":902,"contacts":903},"Chulalongkorn Hospital ( Site 0807)","Bangkok","10330","Thailand","TH",{"type":61,"coordinates":899},[900,901],100.50144,13.75398,{"lat":901,"lon":900},[904],{"name":68,"role":48,"phone":905,"phoneExt":27,"email":27},"+6622564930",{"facility":907,"status":54,"city":894,"state":894,"zip":895,"country":896,"countryCode":897,"cosmosGeoPoint":908,"geoPoint":910,"contacts":911},"HIV Netherlands Australia Thailand Research Collaboration ( Site 0808)",{"type":61,"coordinates":909},[900,901],{"lat":901,"lon":900},[912],{"name":68,"role":48,"phone":913,"phoneExt":27,"email":27},"086-045-1050",{"facility":915,"status":54,"city":894,"state":894,"zip":895,"country":896,"countryCode":897,"cosmosGeoPoint":916,"geoPoint":918,"contacts":919},"Institute of HIV Research and Innovation ( Site 0810)",{"type":61,"coordinates":917},[900,901],{"lat":901,"lon":900},[920],{"name":68,"role":48,"phone":921,"phoneExt":27,"email":27},"+6621605371",{"facility":923,"status":361,"city":894,"state":894,"zip":924,"country":896,"countryCode":897,"cosmosGeoPoint":925,"geoPoint":927,"contacts":27},"Faculty of Medicine Siriraj Hospital ( Site 0806)","10700",{"type":61,"coordinates":926},[900,901],{"lat":901,"lon":900},{"facility":929,"status":54,"city":930,"state":931,"zip":932,"country":896,"countryCode":897,"cosmosGeoPoint":27,"geoPoint":27,"contacts":933},"Research Institute for Health Sciences ( Site 0809)","Muang","Chiang Mai","50200",[934],{"name":68,"role":48,"phone":935,"phoneExt":27,"email":27},"+6653211363",{"facility":937,"status":361,"city":938,"state":938,"zip":939,"country":940,"countryCode":941,"cosmosGeoPoint":942,"geoPoint":946,"contacts":27},"Hanoi Medical University Hospital ( Site 0851)","Hanoi","100000","Vietnam","VN",{"type":61,"coordinates":943},[944,945],105.84117,21.0245,{"lat":945,"lon":944},{"facility":948,"status":361,"city":949,"state":27,"zip":950,"country":940,"countryCode":941,"cosmosGeoPoint":951,"geoPoint":955,"contacts":27},"Thu Duc General Hospital ( Site 0881)","Ho Chi Minh City","700000",{"type":61,"coordinates":952},[953,954],106.62965,10.82302,{"lat":954,"lon":953},{"type":957,"investigatorFullName":27,"investigatorTitle":27,"investigatorAffiliation":27,"oldNameTitle":27,"oldOrganization":27},"SPONSOR","100596349","phase-3-a-clinical-study-of-mk-8527-to-prevent-human-immunodeficiency-virus-type-1-hiv-1-mk-8527-011-100596349",false,"NCT07044297","A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)","A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of MK-8527 Oral Once-Monthly as HIV-1 Preexposure Prophylaxis","Inclusion Criteria:\n\nThe main inclusion criteria include but are not limited to the following:\n\n* Is confirmed HIV-uninfected based on negative HIV-1\u002FHIV-2 test results\n* Is a cisgender man, transgender woman (assigned male sex at birth), transgender man (assigned female sex at birth), or gender nonbinary person\n* Has had condomless receptive anal sex in the 12 months prior to screening (not including sex occurring in a mutually monogamous relationship) and has at least 1 of the following: receptive anal sex with 2 or more partners in the 3 months prior to screening (regardless of condom use), rectal or urethral gonorrhea or chlamydia or incident syphilis in the 6 months prior to screening, or any self-reported stimulant drug use with sex in the 3 months prior to screening\n* Weighs ≥35 kg\n\nExclusion Criteria:\n\nThe main exclusion criteria include but are not limited to the following:\n\n* Has hypersensitivity or other contraindication to any component of the study interventions\n* Has evidence of acute or chronic hepatitis B infection\n* Has a history of malignancy within 5 years of screening except for adequately treated basal cell or squamous cell skin cancer, or in situ anal or cervical cancers\n* Has taken cabotegravir, lenacapavir, or any other long-acting HIV prevention product at any time\n* Is receiving or is anticipated to require any prohibited therapies from 30 days prior to Day 1 through the study duration\n* Has received an HIV vaccine at any time (ie, through past participation in an investigational clinical study) or monoclonal antibodies to HIV within 12 months before Day 1\n* Is expecting to donate eggs at any time during the study",true,"ALL","16 Years",{"count":969,"type":970},4390,"ESTIMATED","INTERVENTIONAL",[973],"PHASE3","Researchers are looking for new medicines to prevent HIV-1 (Human Immunodeficiency Virus Type 1) infection.\n\nThe goals of this study are to learn:\n\n* If taking MK-8527 once a month works to prevent HIV-1 infection as well as or better than a standard (usual) pre-exposure prophylaxis (PrEP) taken once a day\n* About the safety of MK-8527 and if people tolerate it",[976,977],"Human Immunodeficiency Virus (HIV)","HIV Pre-Exposure Prophylaxis","2026-06-25",{"date":980,"type":981},"2026-06-29","ACTUAL",{"date":983,"type":981},"2025-07-31",{"date":985,"type":970},"2027-07-22",{"name":5,"class":6},81]