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County","41346","Sweden","SE",{"type":45,"coordinates":1293},[1294,1295],11.96679,57.70716,{"lat":1295,"lon":1294},{"facility":1298,"status":38,"city":1299,"state":33,"zip":1300,"country":1301,"countryCode":1302,"cosmosGeoPoint":1303,"geoPoint":1307,"contacts":33},"UniversitätsSpital Zürich ( Site 3301)","Zurich","8091","Switzerland","CH",{"type":45,"coordinates":1304},[1305,1306],8.55,47.36667,{"lat":1306,"lon":1305},{"facility":1309,"status":38,"city":1310,"state":33,"zip":1311,"country":1312,"countryCode":1313,"cosmosGeoPoint":1314,"geoPoint":1318,"contacts":33},"Kaohsiung Veteran General Hospital ( Site 3702)","Kaohsiung City","813","Taiwan","TW",{"type":45,"coordinates":1315},[1316,1317],120.31333,22.61626,{"lat":1317,"lon":1316},{"facility":1320,"status":38,"city":1321,"state":33,"zip":1322,"country":1312,"countryCode":1313,"cosmosGeoPoint":1323,"geoPoint":1327,"contacts":33},"National Cheng Kung University Hospital ( Site 3703)","Tainan","704302",{"type":45,"coordinates":1324},[1325,1326],120.21333,22.99083,{"lat":1326,"lon":1325},{"facility":1329,"status":38,"city":1330,"state":1331,"zip":1332,"country":1333,"countryCode":1334,"cosmosGeoPoint":1335,"geoPoint":1339,"contacts":33},"Papworth Hospital NHS Foundation Trust ( Site 1208)","Cambridge","Cambridgeshire","CB2 0AY","United Kingdom","UK",{"type":45,"coordinates":1336},[1337,1338],0.11667,52.2,{"lat":1338,"lon":1337},{"facility":1341,"status":38,"city":1342,"state":1343,"zip":1344,"country":1333,"countryCode":1334,"cosmosGeoPoint":1345,"geoPoint":1349,"contacts":33},"Golden Jubilee National Hospital ( Site 1204)","Glasgow","Glasgow City","G81 4DY",{"type":45,"coordinates":1346},[1347,1348],-4.25763,55.86515,{"lat":1348,"lon":1347},{"facility":1351,"status":38,"city":1352,"state":1353,"zip":1354,"country":1333,"countryCode":1334,"cosmosGeoPoint":1355,"geoPoint":1359,"contacts":33},"Royal Free Hospital ( Site 1202)","London","London, City of","NW3 2QG",{"type":45,"coordinates":1356},[1357,1358],-0.12574,51.50853,{"lat":1358,"lon":1357},{"facility":1361,"status":38,"city":1352,"state":1353,"zip":1362,"country":1333,"countryCode":1334,"cosmosGeoPoint":1363,"geoPoint":1365,"contacts":33},"Royal Brompton Hospital ( Site 1206)","SW3 6NP",{"type":45,"coordinates":1364},[1357,1358],{"lat":1358,"lon":1357},{"facility":1367,"status":38,"city":1352,"state":1353,"zip":1368,"country":1333,"countryCode":1334,"cosmosGeoPoint":1369,"geoPoint":1371,"contacts":33},"Hammersmith Hospital ( Site 1203)","W12 0HS",{"type":45,"coordinates":1370},[1357,1358],{"lat":1358,"lon":1357},{"facility":1373,"status":38,"city":1374,"state":33,"zip":1375,"country":1333,"countryCode":1334,"cosmosGeoPoint":1376,"geoPoint":1380,"contacts":33},"Freeman Hospital ( Site 1205)","Newcastle upon Tyne","NE7 7DN",{"type":45,"coordinates":1377},[1378,1379],-1.61396,54.97328,{"lat":1379,"lon":1378},{"facility":1382,"status":38,"city":1383,"state":33,"zip":1384,"country":1333,"countryCode":1334,"cosmosGeoPoint":1385,"geoPoint":1389,"contacts":33},"Royal Hallamshire Hospital ( Site 1207)","Sheffield","S10 2JF",{"type":45,"coordinates":1386},[1387,1388],-1.4659,53.38297,{"lat":1388,"lon":1387},{"type":1391,"investigatorFullName":33,"investigatorTitle":33,"investigatorAffiliation":33,"oldNameTitle":33,"oldOrganization":33},"SPONSOR","100609703","phase-3-a-clinical-study-of-sotatercept-mk-7962-in-people-with-pulmonary-arterial-hypertension-mk-7962-038-100609703",false,"NCT07218029","A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)","An Open-label Long-term Follow-up Study to Evaluate the Effects of Sotatercept When Added to Background Pulmonary Arterial Hypertension (PAH) Therapy for the Treatment of PAH (MK-7962-038)","SOTERIA","Inclusion Criteria:\n\nThe main inclusion criteria include but are not limited to the following:\n\n* Has completed their current respective PAH sotatercept clinical study and its requirements, and must not have discontinued early\n* Is willing to adhere to the study visit schedule, and understands and will comply with all protocol requirements\n* Must have the ability to understand and provide documented informed consent\n\nExclusion Criteria:\n\nThe main exclusion criteria include but are not limited to the following:\n\n* Did not participate in a sotatercept PAH parent study\n* Missed more than the equivalent of 4 consecutive doses between the end of parent study and the start of this study.\n* Presence of an ongoing serious adverse event that occurred during a PAH sotatercept clinical study that is assessed to be possibly or probably related to sotatercept\n* Is a female who is pregnant or breastfeeding\n* Is or has an immediate family member who is investigational site or Sponsor staff directly involved with this study\n* Is currently enrolled in another investigational product study other than a sotatercept study\n* Is incapacitated","ALL","18 Years",{"count":1403,"type":1404},815,"ESTIMATED","INTERVENTIONAL",[1407],"PHASE3","Researchers are looking for more ways to treat PAH. In PAH, the blood vessels in the lungs become thick and narrow, which makes it harder for blood to flow. This causes high blood pressure in the lungs and overworks the heart. PAH can make it hard to breathe and be active. Some standard (usual) treatments for PAH can treat symptoms of PAH but do not stop PAH from getting worse.\n\nSotatercept is a study medicine designed to treat PAH. It is a targeted therapy, which is a treatment that works on certain proteins that play a role in causing PAH.\n\nThis is a long-term follow-up (LTFU) study. People who took part in certain other studies testing sotatercept for PAH may be able to join this study. The goal of this study is to learn about the long-term safety of sotatercept and if people tolerate it when taken with standard PAH treatment over a longer period of time.",[1410],"Pulmonary Arterial Hypertension","2026-06-25",{"date":1413,"type":1414},"2026-06-26","ACTUAL",{"date":1416,"type":1414},"2021-05-12",{"date":1418,"type":1404},"2028-12-07",{"name":5,"class":6},126]