[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100491907":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":29,"centralContacts":33,"locations":39,"responsibleParty":1283,"collaborators":28,"id":1285,"slug":1286,"hasResults":1287,"nctId":1288,"briefTitle":1289,"officialTitle":1290,"acronym":1291,"eligibilityCriteria":1292,"healthyVolunteers":1287,"sex":1293,"minAge":28,"maxAge":28,"enrollmentInfo":1294,"targetDuration":28,"studyType":1297,"phases":1298,"briefSummary":1300,"conditions":1301,"keywords":28,"overallStatus":42,"whyStopped":28,"lastUpdateSubmitDate":1304,"lastUpdatePostDateStruct":1305,"startDateStruct":1308,"completionDateStruct":1310,"leadSponsor":1312,"locationsCount":1313},{"fullName":5,"class":6},"Novo Nordisk A\u002FS","INDUSTRY",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Arm 1","EXPERIMENTAL","Participants entering from the multiple ascending dose (MAD) part of study NN7769-4513. In part 1, participants will receive Mim8 prophylaxis (PPX) subcutaneous (s.c.) administration using enhanced cartridge for 26 weeks. In part 2, participants will receive Mim8 PPX s.c. administration using enhanced cartridge or DV3407 pen-injector once it is approved.",[13],"Drug: Mim8",{"label":15,"type":10,"description":16,"interventionNames":17},"Arm 2","Participants entering from study NN7769-4514, NN7769-4728 and NN7769-4516. In part 1, participants will receive Mim8 PPX s.c. administration using DV3407 pen-injector for 26 weeks. In part 2, participants will receive Mim8 PPX s.c. administration using DV3407 pen-injector.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Arm 3","In part 1 and 2, participants will receive Mim8 PPX s.c. administration using DV3407 pen-injector.",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"DRUG","Mim8","Participants in arm 1 will administer Mim8 using an enhanced cartridge and switch to the DV3407 pen-injector once it is approved. Participants in arm 2 and 3 will use the DV3407 pen injector.",[9,15,19],null,[30],{"name":31,"affiliation":5,"role":32},"Clinical Transparency dept. 2834","STUDY_DIRECTOR",[34],{"name":35,"role":36,"phone":37,"phoneExt":28,"email":38},"Novo Nordisk","CONTACT","(+1) 866-867-7178","clinicaltrials@novonordisk.com",[40,54,64,74,84,94,105,111,121,131,141,151,160,170,179,189,200,205,214,218,229,238,249,261,270,282,287,297,302,312,317,327,337,342,352,362,367,377,381,392,403,412,417,426,431,440,444,455,464,473,485,489,499,508,512,522,526,536,546,556,560,572,576,587,599,608,617,623,632,637,646,650,654,663,674,678,687,696,705,710,719,725,731,742,748,759,765,777,787,791,802,813,822,834,844,854,859,868,877,881,885,896,905,914,920,931,942,953,962,973,982,991,1003,1007,1017,1021,1030,1034,1040,1045,1056,1060,1069,1078,1083,1094,1103,1112,1121,1132,1138,1147,1152,1163,1168,1172,1174,1184,1193,1199,1204,1209,1213,1215,1224,1229,1240,1249,1258,1263,1269,1274],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":28},"Children's Hospital Los Angeles - Endocrinology","RECRUITING","Los Angeles","California","90027","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-118.24368,34.05223,{"lat":52,"lon":51},{"facility":55,"status":42,"city":56,"state":57,"zip":58,"country":46,"countryCode":47,"cosmosGeoPoint":59,"geoPoint":63,"contacts":28},"UC Denver Hemoph & Thrombo Ctr","Aurora","Colorado","80045",{"type":49,"coordinates":60},[61,62],-104.83192,39.72943,{"lat":62,"lon":61},{"facility":65,"status":42,"city":66,"state":67,"zip":68,"country":46,"countryCode":47,"cosmosGeoPoint":69,"geoPoint":73,"contacts":28},"Univ of Miami\u002FSCCC","Miami","Florida","33136",{"type":49,"coordinates":70},[71,72],-80.19366,25.77427,{"lat":72,"lon":71},{"facility":75,"status":76,"city":77,"state":67,"zip":78,"country":46,"countryCode":47,"cosmosGeoPoint":79,"geoPoint":83,"contacts":28},"St Joseph's Hospital Foundation","ACTIVE_NOT_RECRUITING","Tampa","33607",{"type":49,"coordinates":80},[81,82],-82.45843,27.94752,{"lat":82,"lon":81},{"facility":85,"status":42,"city":86,"state":87,"zip":88,"country":46,"countryCode":47,"cosmosGeoPoint":89,"geoPoint":93,"contacts":28},"Children's Healthcare Atlanta","Atlanta","Georgia","30329",{"type":49,"coordinates":90},[91,92],-84.38798,33.749,{"lat":92,"lon":91},{"facility":95,"status":96,"city":97,"state":98,"zip":99,"country":46,"countryCode":47,"cosmosGeoPoint":100,"geoPoint":104,"contacts":28},"Rush University Med. Cntr","COMPLETED","Chicago","Illinois","60612",{"type":49,"coordinates":101},[102,103],-87.65005,41.85003,{"lat":103,"lon":102},{"facility":106,"status":107,"city":97,"state":98,"zip":99,"country":46,"countryCode":47,"cosmosGeoPoint":108,"geoPoint":110,"contacts":28},"Rush University Medical Center","NOT_YET_RECRUITING",{"type":49,"coordinates":109},[102,103],{"lat":103,"lon":102},{"facility":112,"status":96,"city":113,"state":114,"zip":115,"country":46,"countryCode":47,"cosmosGeoPoint":116,"geoPoint":120,"contacts":28},"Indiana Hemophilia-Thromb Ctr","Indianapolis","Indiana","46260",{"type":49,"coordinates":117},[118,119],-86.15804,39.76838,{"lat":119,"lon":118},{"facility":122,"status":42,"city":123,"state":124,"zip":125,"country":46,"countryCode":47,"cosmosGeoPoint":126,"geoPoint":130,"contacts":28},"University of Iowa_Iowa City","Iowa City","Iowa","52242",{"type":49,"coordinates":127},[128,129],-91.53017,41.66113,{"lat":129,"lon":128},{"facility":132,"status":42,"city":133,"state":134,"zip":135,"country":46,"countryCode":47,"cosmosGeoPoint":136,"geoPoint":140,"contacts":28},"Central Michigan University","Detroit","Michigan","48201",{"type":49,"coordinates":137},[138,139],-83.04575,42.33143,{"lat":139,"lon":138},{"facility":142,"status":42,"city":143,"state":144,"zip":145,"country":46,"countryCode":47,"cosmosGeoPoint":146,"geoPoint":150,"contacts":28},"Univ Hosp Cleveland Med Ctr","Cleveland","Ohio","44106",{"type":49,"coordinates":147},[148,149],-81.69541,41.4995,{"lat":149,"lon":148},{"facility":152,"status":42,"city":153,"state":144,"zip":154,"country":46,"countryCode":47,"cosmosGeoPoint":155,"geoPoint":159,"contacts":28},"Dayton Children Hemostati Ctr","Dayton","45404",{"type":49,"coordinates":156},[157,158],-84.19161,39.75895,{"lat":158,"lon":157},{"facility":161,"status":42,"city":162,"state":163,"zip":164,"country":46,"countryCode":47,"cosmosGeoPoint":165,"geoPoint":169,"contacts":28},"Penn State MS Hershey Med Ctr","Hershey","Pennsylvania","17033-2360",{"type":49,"coordinates":166},[167,168],-76.65025,40.28592,{"lat":168,"lon":167},{"facility":171,"status":42,"city":172,"state":163,"zip":173,"country":46,"countryCode":47,"cosmosGeoPoint":174,"geoPoint":178,"contacts":28},"St Christopher Hosp for Child","Philadelphia","19134",{"type":49,"coordinates":175},[176,177],-75.16362,39.95238,{"lat":177,"lon":176},{"facility":180,"status":42,"city":181,"state":182,"zip":183,"country":46,"countryCode":47,"cosmosGeoPoint":184,"geoPoint":188,"contacts":28},"Vanderbilt U Med Ctr_Nashville","Nashville","Tennessee","37212",{"type":49,"coordinates":185},[186,187],-86.78444,36.16589,{"lat":187,"lon":186},{"facility":190,"status":76,"city":191,"state":28,"zip":192,"country":193,"countryCode":194,"cosmosGeoPoint":195,"geoPoint":199,"contacts":28},"Universitätsklinik für Innere Medizin V","Innsbruck","6020","Austria","AT",{"type":49,"coordinates":196},[197,198],11.39454,47.26266,{"lat":198,"lon":197},{"facility":190,"status":107,"city":191,"state":28,"zip":201,"country":193,"countryCode":194,"cosmosGeoPoint":202,"geoPoint":204,"contacts":28},"A 6020",{"type":49,"coordinates":203},[197,198],{"lat":198,"lon":197},{"facility":206,"status":76,"city":207,"state":28,"zip":208,"country":193,"countryCode":194,"cosmosGeoPoint":209,"geoPoint":213,"contacts":28},"AKH - Klin. Abt. f. Haematologie u. Haemostaseologie","Vienna","1090",{"type":49,"coordinates":210},[211,212],16.37208,48.20849,{"lat":212,"lon":211},{"facility":206,"status":107,"city":207,"state":28,"zip":208,"country":193,"countryCode":194,"cosmosGeoPoint":215,"geoPoint":217,"contacts":28},{"type":49,"coordinates":216},[211,212],{"lat":212,"lon":211},{"facility":219,"status":76,"city":220,"state":28,"zip":221,"country":222,"countryCode":223,"cosmosGeoPoint":224,"geoPoint":228,"contacts":28},"Cliniques universitaires Saint-Luc - Service Hématologie","Brussels","1200","Belgium","BE",{"type":49,"coordinates":225},[226,227],4.34878,50.85045,{"lat":227,"lon":226},{"facility":230,"status":76,"city":231,"state":28,"zip":232,"country":222,"countryCode":223,"cosmosGeoPoint":233,"geoPoint":237,"contacts":28},"UZ Leuven - Kindergeneeskunde","Leuven","3000",{"type":49,"coordinates":234},[235,236],4.70093,50.87959,{"lat":236,"lon":235},{"facility":239,"status":76,"city":240,"state":28,"zip":241,"country":242,"countryCode":243,"cosmosGeoPoint":244,"geoPoint":248,"contacts":28},"SHAT of Haematological Diseases EAD, Clinic of Paediatric Clinical Haematology","Sofia","1797","Bulgaria","BG",{"type":49,"coordinates":245},[246,247],23.32415,42.69751,{"lat":247,"lon":246},{"facility":250,"status":76,"city":251,"state":252,"zip":253,"country":254,"countryCode":255,"cosmosGeoPoint":256,"geoPoint":260,"contacts":28},"McMaster University","Hamilton","Ontario","L8N 3Z5","Canada","CA",{"type":49,"coordinates":257},[258,259],-79.84963,43.25011,{"lat":259,"lon":258},{"facility":262,"status":76,"city":263,"state":252,"zip":264,"country":254,"countryCode":255,"cosmosGeoPoint":265,"geoPoint":269,"contacts":28},"The Hospital for Sick Children","Toronto","M5G 1X8",{"type":49,"coordinates":266},[267,268],-79.39864,43.70643,{"lat":268,"lon":267},{"facility":271,"status":76,"city":272,"state":273,"zip":274,"country":275,"countryCode":276,"cosmosGeoPoint":277,"geoPoint":281,"contacts":28},"Beijing Children's Hospital, Capital Medical University","Beijing","Beijing Municipality","100045","China","CN",{"type":49,"coordinates":278},[279,280],116.39723,39.9075,{"lat":280,"lon":279},{"facility":283,"status":42,"city":272,"state":273,"zip":274,"country":275,"countryCode":276,"cosmosGeoPoint":284,"geoPoint":286,"contacts":28},"Beijing Children's Hospital，Capital Medical University",{"type":49,"coordinates":285},[279,280],{"lat":280,"lon":279},{"facility":288,"status":107,"city":289,"state":290,"zip":291,"country":275,"countryCode":276,"cosmosGeoPoint":292,"geoPoint":296,"contacts":28},"Haemotology, Nanfang Hospital, Southern Medical University","Guangzhou","Guangdong","510515",{"type":49,"coordinates":293},[294,295],113.25,23.11667,{"lat":295,"lon":294},{"facility":298,"status":76,"city":289,"state":290,"zip":291,"country":275,"countryCode":276,"cosmosGeoPoint":299,"geoPoint":301,"contacts":28},"Nanfang Hospital, Southern Medical University-Haematology",{"type":49,"coordinates":300},[294,295],{"lat":295,"lon":294},{"facility":303,"status":76,"city":304,"state":305,"zip":306,"country":275,"countryCode":276,"cosmosGeoPoint":307,"geoPoint":311,"contacts":28},"Tongji Hospital, Tongji Medical College of HUST-Hematology","Wuhan","Hubei","430030",{"type":49,"coordinates":308},[309,310],114.26667,30.58333,{"lat":310,"lon":309},{"facility":313,"status":42,"city":304,"state":305,"zip":306,"country":275,"countryCode":276,"cosmosGeoPoint":314,"geoPoint":316,"contacts":28},"Tongji Hospital, Tongji Medical College of HUST",{"type":49,"coordinates":315},[309,310],{"lat":310,"lon":309},{"facility":318,"status":76,"city":319,"state":320,"zip":321,"country":275,"countryCode":276,"cosmosGeoPoint":322,"geoPoint":326,"contacts":28},"Xiangya Hospital Central-South University","Changsha","Hunan","410008",{"type":49,"coordinates":323},[324,325],112.97087,28.19874,{"lat":325,"lon":324},{"facility":328,"status":76,"city":329,"state":330,"zip":331,"country":275,"countryCode":276,"cosmosGeoPoint":332,"geoPoint":336,"contacts":28},"Jinan Central Hospital Affiliated to Shandong University","Jinan","Shandong","250062",{"type":49,"coordinates":333},[334,335],116.99722,36.66833,{"lat":335,"lon":334},{"facility":338,"status":76,"city":329,"state":330,"zip":331,"country":275,"countryCode":276,"cosmosGeoPoint":339,"geoPoint":341,"contacts":28},"Jinan Central Hospital",{"type":49,"coordinates":340},[334,335],{"lat":335,"lon":334},{"facility":343,"status":76,"city":344,"state":345,"zip":346,"country":275,"countryCode":276,"cosmosGeoPoint":347,"geoPoint":351,"contacts":28},"Chengdu Women's and Children's Central Hospital","Chengdu","Sichuan","610074",{"type":49,"coordinates":348},[349,350],104.06667,30.66667,{"lat":350,"lon":349},{"facility":353,"status":76,"city":354,"state":355,"zip":356,"country":275,"countryCode":276,"cosmosGeoPoint":357,"geoPoint":361,"contacts":28},"Institute of Hematology and Blood Diseases Hospital, Tianjin-Hematology","Tianjin","Tianjin Municipality","300020",{"type":49,"coordinates":358},[359,360],117.17667,39.14222,{"lat":360,"lon":359},{"facility":363,"status":42,"city":354,"state":355,"zip":356,"country":275,"countryCode":276,"cosmosGeoPoint":364,"geoPoint":366,"contacts":28},"Institute of hematology and Blood Diseases Hospital, Tianjin-Hematology",{"type":49,"coordinates":365},[359,360],{"lat":360,"lon":359},{"facility":368,"status":76,"city":369,"state":370,"zip":371,"country":275,"countryCode":276,"cosmosGeoPoint":372,"geoPoint":376,"contacts":28},"Children's Hospital, Zhejiang University School of Medicine-Hematology","Huzhou","Zhejiang","313200",{"type":49,"coordinates":373},[374,375],120.0933,30.8703,{"lat":375,"lon":374},{"facility":338,"status":42,"city":329,"state":28,"zip":331,"country":275,"countryCode":276,"cosmosGeoPoint":378,"geoPoint":380,"contacts":28},{"type":49,"coordinates":379},[334,335],{"lat":335,"lon":334},{"facility":382,"status":76,"city":383,"state":28,"zip":384,"country":385,"countryCode":386,"cosmosGeoPoint":387,"geoPoint":391,"contacts":28},"Rigshospitalet - Department of Haematology, 2081","København Ø","2100","Denmark","DK",{"type":49,"coordinates":388},[389,390],12.56862,55.70968,{"lat":390,"lon":389},{"facility":393,"status":76,"city":394,"state":28,"zip":395,"country":396,"countryCode":397,"cosmosGeoPoint":398,"geoPoint":402,"contacts":28},"Hospices Civils de Lyon- Hopital Louis Pradel","Bron","69500","France","FR",{"type":49,"coordinates":399},[400,401],4.91303,45.73865,{"lat":401,"lon":400},{"facility":404,"status":107,"city":405,"state":28,"zip":406,"country":396,"countryCode":397,"cosmosGeoPoint":407,"geoPoint":411,"contacts":28},"Ap-Hp-Hopital de Bicetre-1","Le Kremlin-Bicêtre","94275",{"type":49,"coordinates":408},[409,410],2.36073,48.81471,{"lat":410,"lon":409},{"facility":413,"status":76,"city":405,"state":28,"zip":406,"country":396,"countryCode":397,"cosmosGeoPoint":414,"geoPoint":416,"contacts":28},"Ap-Hp-Hopital de Bicetre",{"type":49,"coordinates":415},[409,410],{"lat":410,"lon":409},{"facility":418,"status":107,"city":419,"state":28,"zip":420,"country":396,"countryCode":397,"cosmosGeoPoint":421,"geoPoint":425,"contacts":28},"Centre Hospitalier Universitaire de Lille-Institut Coeur Poumon","Lille","59037",{"type":49,"coordinates":422},[423,424],3.05512,50.63391,{"lat":424,"lon":423},{"facility":427,"status":76,"city":419,"state":28,"zip":420,"country":396,"countryCode":397,"cosmosGeoPoint":428,"geoPoint":430,"contacts":28},"INSTITUT COEUR POUMON_Service d'hémostase et transfusion",{"type":49,"coordinates":429},[423,424],{"lat":424,"lon":423},{"facility":432,"status":76,"city":433,"state":28,"zip":434,"country":396,"countryCode":397,"cosmosGeoPoint":435,"geoPoint":439,"contacts":28},"Centre Hospitalier Universitaire de Nantes-Hopital Hotel-Dieu","Nantes","44000",{"type":49,"coordinates":436},[437,438],-1.55336,47.21725,{"lat":438,"lon":437},{"facility":432,"status":107,"city":433,"state":28,"zip":433,"country":396,"countryCode":397,"cosmosGeoPoint":441,"geoPoint":443,"contacts":28},{"type":49,"coordinates":442},[437,438],{"lat":438,"lon":437},{"facility":445,"status":42,"city":446,"state":28,"zip":447,"country":448,"countryCode":449,"cosmosGeoPoint":450,"geoPoint":454,"contacts":28},"Vivantes Netzwerk für Gesundheit GmbH - Vivantes Klinikum im Friedrichshain","Berlin","10249","Germany","DE",{"type":49,"coordinates":451},[452,453],13.41053,52.52437,{"lat":453,"lon":452},{"facility":456,"status":42,"city":457,"state":28,"zip":458,"country":448,"countryCode":449,"cosmosGeoPoint":459,"geoPoint":463,"contacts":28},"Universitätsklinikum Bonn - Institut für Experimentelle Hämatologie","Bonn","53127",{"type":49,"coordinates":460},[461,462],7.09549,50.73438,{"lat":462,"lon":461},{"facility":465,"status":76,"city":466,"state":28,"zip":467,"country":448,"countryCode":449,"cosmosGeoPoint":468,"geoPoint":472,"contacts":28},"HZRM Haemophilie-Zentrum Rhein Main GmbH","Frankfurt am Main","60596",{"type":49,"coordinates":469},[470,471],8.68417,50.11552,{"lat":471,"lon":470},{"facility":474,"status":76,"city":475,"state":476,"zip":477,"country":478,"countryCode":479,"cosmosGeoPoint":480,"geoPoint":484,"contacts":28},"Nirmal Hospital Pvt. Ltd.","Surat","Gujarat","395002","India","IN",{"type":49,"coordinates":481},[482,483],72.83023,21.19594,{"lat":483,"lon":482},{"facility":474,"status":42,"city":475,"state":476,"zip":477,"country":478,"countryCode":479,"cosmosGeoPoint":486,"geoPoint":488,"contacts":28},{"type":49,"coordinates":487},[482,483],{"lat":483,"lon":482},{"facility":490,"status":76,"city":491,"state":492,"zip":493,"country":478,"countryCode":479,"cosmosGeoPoint":494,"geoPoint":498,"contacts":28},"Seth GS medical college and KEM Hospital","Mumbai","Maharashtra","400012",{"type":49,"coordinates":495},[496,497],72.88261,19.07283,{"lat":497,"lon":496},{"facility":500,"status":76,"city":501,"state":492,"zip":502,"country":478,"countryCode":479,"cosmosGeoPoint":503,"geoPoint":507,"contacts":28},"Sahyadri Clinical Research And Development Center","Pune","411004",{"type":49,"coordinates":504},[505,506],73.85535,18.51957,{"lat":506,"lon":505},{"facility":500,"status":42,"city":501,"state":492,"zip":502,"country":478,"countryCode":479,"cosmosGeoPoint":509,"geoPoint":511,"contacts":28},{"type":49,"coordinates":510},[505,506],{"lat":506,"lon":505},{"facility":513,"status":76,"city":514,"state":515,"zip":516,"country":478,"countryCode":479,"cosmosGeoPoint":517,"geoPoint":521,"contacts":28},"Christian Medical College and Hospital","Ludhiana","Punjab","141008",{"type":49,"coordinates":518},[519,520],75.85379,30.91204,{"lat":520,"lon":519},{"facility":513,"status":42,"city":514,"state":515,"zip":516,"country":478,"countryCode":479,"cosmosGeoPoint":523,"geoPoint":525,"contacts":28},{"type":49,"coordinates":524},[519,520],{"lat":520,"lon":519},{"facility":527,"status":76,"city":528,"state":529,"zip":530,"country":478,"countryCode":479,"cosmosGeoPoint":531,"geoPoint":535,"contacts":28},"SMS Medical College & Hospital","Jaipur","Rajasthan","302004",{"type":49,"coordinates":532},[533,534],75.78781,26.91962,{"lat":534,"lon":533},{"facility":537,"status":76,"city":538,"state":539,"zip":540,"country":478,"countryCode":479,"cosmosGeoPoint":541,"geoPoint":545,"contacts":28},"CMCV","Ranipet","Tamil Nadu","632517",{"type":49,"coordinates":542},[543,544],79.33331,12.92471,{"lat":544,"lon":543},{"facility":547,"status":76,"city":548,"state":549,"zip":550,"country":478,"countryCode":479,"cosmosGeoPoint":551,"geoPoint":555,"contacts":28},"Post Graduate Institute of Child Health","Noida","Uttar Pradesh","201303",{"type":49,"coordinates":552},[553,554],77.33,28.58,{"lat":554,"lon":553},{"facility":490,"status":76,"city":491,"state":28,"zip":493,"country":478,"countryCode":479,"cosmosGeoPoint":557,"geoPoint":559,"contacts":28},{"type":49,"coordinates":558},[496,497],{"lat":497,"lon":496},{"facility":561,"status":76,"city":562,"state":563,"zip":564,"country":565,"countryCode":566,"cosmosGeoPoint":567,"geoPoint":571,"contacts":28},"St James's CRF","Dublin","Leinster","D08 A978","Ireland","IE",{"type":49,"coordinates":568},[569,570],-6.24889,53.33306,{"lat":570,"lon":569},{"facility":561,"status":107,"city":562,"state":563,"zip":564,"country":565,"countryCode":566,"cosmosGeoPoint":573,"geoPoint":575,"contacts":28},{"type":49,"coordinates":574},[569,570],{"lat":570,"lon":569},{"facility":577,"status":42,"city":578,"state":28,"zip":579,"country":580,"countryCode":581,"cosmosGeoPoint":582,"geoPoint":586,"contacts":28},"Sheba MC - The Israeli National Hemophilia Center","Tel Litwinsky","52621","Israel","IL",{"type":49,"coordinates":583},[584,585],34.84588,32.05096,{"lat":585,"lon":584},{"facility":588,"status":76,"city":589,"state":590,"zip":591,"country":592,"countryCode":593,"cosmosGeoPoint":594,"geoPoint":598,"contacts":28},"A.O.U. Policlinico Umberto I","Rome","Lazio","00161","Italy","IT",{"type":49,"coordinates":595},[596,597],12.51133,41.89193,{"lat":597,"lon":596},{"facility":600,"status":76,"city":601,"state":28,"zip":602,"country":592,"countryCode":593,"cosmosGeoPoint":603,"geoPoint":607,"contacts":28},"AOU Careggi Firenze","Florence","50134",{"type":49,"coordinates":604},[605,606],11.24626,43.77925,{"lat":606,"lon":605},{"facility":609,"status":76,"city":610,"state":28,"zip":611,"country":592,"countryCode":593,"cosmosGeoPoint":612,"geoPoint":616,"contacts":28},"IRCCS Humanitas Research Hospital - Centro Trombosi e Malattie Emorragiche","Milan","20089",{"type":49,"coordinates":613},[614,615],12.59836,42.78235,{"lat":615,"lon":614},{"facility":618,"status":76,"city":610,"state":28,"zip":619,"country":592,"countryCode":593,"cosmosGeoPoint":620,"geoPoint":622,"contacts":28},"Fondazione IRCSS Ca' Granda Ospedale Maggiore Policlinico","20122",{"type":49,"coordinates":621},[614,615],{"lat":615,"lon":614},{"facility":624,"status":42,"city":625,"state":28,"zip":626,"country":592,"countryCode":593,"cosmosGeoPoint":627,"geoPoint":631,"contacts":28},"Azienda Ospedaliera di Rilievo Nazionale Santobono Pausilipon","Naples","80122",{"type":49,"coordinates":628},[629,630],14.26811,40.85216,{"lat":630,"lon":629},{"facility":633,"status":76,"city":625,"state":28,"zip":626,"country":592,"countryCode":593,"cosmosGeoPoint":634,"geoPoint":636,"contacts":28},"Azienda Ospedaliera Santobono Pausilipon - U.S.D. Centro Regionale Pediatrico Malattie della Coagulazione",{"type":49,"coordinates":635},[629,630],{"lat":630,"lon":629},{"facility":638,"status":76,"city":639,"state":28,"zip":640,"country":592,"countryCode":593,"cosmosGeoPoint":641,"geoPoint":645,"contacts":28},"Ospedale Pediatrico Bambino Ges","Roma","00165",{"type":49,"coordinates":642},[643,644],11.10642,44.99364,{"lat":644,"lon":643},{"facility":638,"status":42,"city":639,"state":28,"zip":640,"country":592,"countryCode":593,"cosmosGeoPoint":647,"geoPoint":649,"contacts":28},{"type":49,"coordinates":648},[643,644],{"lat":644,"lon":643},{"facility":588,"status":76,"city":589,"state":28,"zip":591,"country":592,"countryCode":593,"cosmosGeoPoint":651,"geoPoint":653,"contacts":28},{"type":49,"coordinates":652},[596,597],{"lat":597,"lon":596},{"facility":655,"status":96,"city":656,"state":28,"zip":657,"country":592,"countryCode":593,"cosmosGeoPoint":658,"geoPoint":662,"contacts":28},"AOU Città della Salute e della Scienza di Torino - Ospedale Regina Margherita","Torino","10126",{"type":49,"coordinates":659},[660,661],11.99138,44.88856,{"lat":661,"lon":660},{"facility":664,"status":76,"city":665,"state":28,"zip":666,"country":667,"countryCode":668,"cosmosGeoPoint":669,"geoPoint":673,"contacts":28},"Nagoya University Hospital_Blood Transfusion","Aichi","466-8560","Japan","JP",{"type":49,"coordinates":670},[671,672],130.62158,32.51879,{"lat":672,"lon":671},{"facility":675,"status":42,"city":676,"state":28,"zip":677,"country":667,"countryCode":668,"cosmosGeoPoint":28,"geoPoint":28,"contacts":28},"Ota Memorial Hospital_Pediatrics","Gunma","373-8585",{"facility":679,"status":42,"city":680,"state":28,"zip":681,"country":667,"countryCode":668,"cosmosGeoPoint":682,"geoPoint":686,"contacts":28},"Nara Medical University Hospital_Pediatrics","Nara","634-8522",{"type":49,"coordinates":683},[684,685],135.80485,34.68505,{"lat":685,"lon":684},{"facility":688,"status":42,"city":689,"state":28,"zip":690,"country":667,"countryCode":668,"cosmosGeoPoint":691,"geoPoint":695,"contacts":28},"Saitama Children's Med Centre_Hematology-Oncology","Saitama","330-8777",{"type":49,"coordinates":692},[693,694],139.65657,35.90807,{"lat":694,"lon":693},{"facility":697,"status":76,"city":698,"state":28,"zip":699,"country":667,"countryCode":668,"cosmosGeoPoint":700,"geoPoint":704,"contacts":28},"Jichi Medical University Hospital_Hematology","Tochigi","329-0498",{"type":49,"coordinates":701},[702,703],139.73333,36.38333,{"lat":703,"lon":702},{"facility":706,"status":76,"city":698,"state":28,"zip":699,"country":667,"countryCode":668,"cosmosGeoPoint":707,"geoPoint":709,"contacts":28},"Jichi Medical University Hospital_Pediatrics",{"type":49,"coordinates":708},[702,703],{"lat":703,"lon":702},{"facility":711,"status":76,"city":712,"state":28,"zip":713,"country":667,"countryCode":668,"cosmosGeoPoint":714,"geoPoint":718,"contacts":28},"National Center for Child Health and Development_Hematology","Tokyo","157-8535",{"type":49,"coordinates":715},[716,717],139.69171,35.6895,{"lat":717,"lon":716},{"facility":720,"status":76,"city":712,"state":28,"zip":721,"country":667,"countryCode":668,"cosmosGeoPoint":722,"geoPoint":724,"contacts":28},"Tokyo Medical Univ. Hospital_Laboratory Medicine","160-0023",{"type":49,"coordinates":723},[716,717],{"lat":717,"lon":716},{"facility":726,"status":76,"city":712,"state":28,"zip":727,"country":667,"countryCode":668,"cosmosGeoPoint":728,"geoPoint":730,"contacts":28},"Ogikubo Hospital_Pediatries & Blood","167-0035",{"type":49,"coordinates":729},[716,717],{"lat":717,"lon":716},{"facility":732,"status":76,"city":733,"state":28,"zip":734,"country":735,"countryCode":736,"cosmosGeoPoint":737,"geoPoint":741,"contacts":28},"Stradini Clinic of Oncology","Riga","1002","Latvia","LV",{"type":49,"coordinates":738},[739,740],24.10589,56.946,{"lat":740,"lon":739},{"facility":743,"status":76,"city":733,"state":28,"zip":744,"country":735,"countryCode":736,"cosmosGeoPoint":745,"geoPoint":747,"contacts":28},"Children University Clinical Hospital","1004",{"type":49,"coordinates":746},[739,740],{"lat":740,"lon":739},{"facility":749,"status":76,"city":750,"state":28,"zip":751,"country":752,"countryCode":753,"cosmosGeoPoint":754,"geoPoint":758,"contacts":28},"Vilnius University hospital Santaros klinikos","Vilnius","08661","Lithuania","LT",{"type":49,"coordinates":755},[756,757],25.2798,54.68916,{"lat":757,"lon":756},{"facility":760,"status":76,"city":750,"state":28,"zip":761,"country":752,"countryCode":753,"cosmosGeoPoint":762,"geoPoint":764,"contacts":28},"Centre of Oncology and Hematology, Vilnius University","LT-08406",{"type":49,"coordinates":763},[756,757],{"lat":757,"lon":756},{"facility":766,"status":76,"city":767,"state":768,"zip":769,"country":770,"countryCode":771,"cosmosGeoPoint":772,"geoPoint":776,"contacts":28},"Hospital Queen Elizabeth 1","Kota Kinabalu","Sabah","88586","Malaysia","MY",{"type":49,"coordinates":773},[774,775],116.0724,5.9749,{"lat":775,"lon":774},{"facility":778,"status":76,"city":779,"state":780,"zip":781,"country":770,"countryCode":771,"cosmosGeoPoint":782,"geoPoint":786,"contacts":28},"Hospital Ampang","Ampang, Selangor","Selangor","68000",{"type":49,"coordinates":783},[784,785],101.25,3.35,{"lat":785,"lon":784},{"facility":778,"status":42,"city":779,"state":780,"zip":781,"country":770,"countryCode":771,"cosmosGeoPoint":788,"geoPoint":790,"contacts":28},{"type":49,"coordinates":789},[784,785],{"lat":785,"lon":784},{"facility":792,"status":76,"city":793,"state":28,"zip":794,"country":795,"countryCode":796,"cosmosGeoPoint":797,"geoPoint":801,"contacts":28},"Centro Multidisciplinario Para El Desarrollo Especializado De La Investigación Clínica En Yucatán S.C.P. (CEMDEICY S.C.P.)","Mérida","97130","Mexico","MX",{"type":49,"coordinates":798},[799,800],-89.62318,20.967,{"lat":800,"lon":799},{"facility":803,"status":76,"city":804,"state":28,"zip":805,"country":806,"countryCode":807,"cosmosGeoPoint":808,"geoPoint":812,"contacts":28},"AmsterdamUMC AMC","Amsterdam","1105 AZ","Netherlands","NL",{"type":49,"coordinates":809},[810,811],4.88969,52.37403,{"lat":811,"lon":810},{"facility":814,"status":76,"city":815,"state":28,"zip":816,"country":806,"countryCode":807,"cosmosGeoPoint":817,"geoPoint":821,"contacts":28},"UMC Utrecht, Van Creveldkliniek","Utrecht","3584 CX",{"type":49,"coordinates":818},[819,820],5.12222,52.09083,{"lat":820,"lon":819},{"facility":823,"status":76,"city":824,"state":825,"zip":826,"country":827,"countryCode":828,"cosmosGeoPoint":829,"geoPoint":833,"contacts":28},"Uniwersytecki Szpital Kliniczny W Poznaniu","Poznan","Greater Poland Voivodeship","60-569","Poland","PL",{"type":49,"coordinates":830},[831,832],16.92993,52.40692,{"lat":832,"lon":831},{"facility":835,"status":42,"city":836,"state":837,"zip":838,"country":827,"countryCode":828,"cosmosGeoPoint":839,"geoPoint":843,"contacts":28},"Uniwersytecki Szpital Kliniczny im. J.Mikulicza-Radeckiego","Wroclaw","Lower Silesian Voivodeship","50-556",{"type":49,"coordinates":840},[841,842],17.03006,51.10286,{"lat":842,"lon":841},{"facility":845,"status":76,"city":846,"state":847,"zip":848,"country":827,"countryCode":828,"cosmosGeoPoint":849,"geoPoint":853,"contacts":28},"Instytut Hematologii i Transfuzjologii","Warsaw","Masovian Voivodeship","02-776",{"type":49,"coordinates":850},[851,852],21.01178,52.22977,{"lat":852,"lon":851},{"facility":855,"status":42,"city":846,"state":847,"zip":848,"country":827,"countryCode":828,"cosmosGeoPoint":856,"geoPoint":858,"contacts":28},"Intytut Hematologii i Transfuzjologii",{"type":49,"coordinates":857},[851,852],{"lat":852,"lon":851},{"facility":860,"status":76,"city":861,"state":28,"zip":862,"country":827,"countryCode":828,"cosmosGeoPoint":863,"geoPoint":867,"contacts":28},"Szpital Uniwersytecki, Oddzial Kliniczny Hematologii","Krakow","30-688",{"type":49,"coordinates":864},[865,866],19.93658,50.06143,{"lat":866,"lon":865},{"facility":869,"status":42,"city":870,"state":28,"zip":871,"country":827,"countryCode":828,"cosmosGeoPoint":872,"geoPoint":876,"contacts":28},"Uniwersytecki Szpital Dzieciecy, Dzial Krwiolecznictwa","Lublin","20-093",{"type":49,"coordinates":873},[874,875],22.57009,51.25058,{"lat":875,"lon":874},{"facility":869,"status":76,"city":870,"state":28,"zip":871,"country":827,"countryCode":828,"cosmosGeoPoint":878,"geoPoint":880,"contacts":28},{"type":49,"coordinates":879},[874,875],{"lat":875,"lon":874},{"facility":835,"status":76,"city":836,"state":28,"zip":838,"country":827,"countryCode":828,"cosmosGeoPoint":882,"geoPoint":884,"contacts":28},{"type":49,"coordinates":883},[841,842],{"lat":842,"lon":841},{"facility":886,"status":76,"city":887,"state":28,"zip":888,"country":889,"countryCode":890,"cosmosGeoPoint":891,"geoPoint":895,"contacts":28},"Unidade De Coimbra, E.P.E. - Hospital da Universidade de Coimbra","Coimbra","3000-459","Portugal","PT",{"type":49,"coordinates":892},[893,894],-8.41996,40.20686,{"lat":894,"lon":893},{"facility":897,"status":76,"city":898,"state":28,"zip":899,"country":889,"countryCode":890,"cosmosGeoPoint":900,"geoPoint":904,"contacts":28},"ULS De São José, E.P.E.- Hospital D. Estefânia","Lisbon","1169-045",{"type":49,"coordinates":901},[902,903],-9.1498,38.72509,{"lat":903,"lon":902},{"facility":906,"status":76,"city":907,"state":28,"zip":908,"country":889,"countryCode":890,"cosmosGeoPoint":909,"geoPoint":913,"contacts":28},"ULS De Santo António, E.P.E. _H.Santo António_ Imunohemoterapia","Porto","4050-342",{"type":49,"coordinates":910},[911,912],-8.61097,41.1485,{"lat":912,"lon":911},{"facility":915,"status":76,"city":907,"state":28,"zip":916,"country":889,"countryCode":890,"cosmosGeoPoint":917,"geoPoint":919,"contacts":28},"ULS São João, E.P.E._H.São João_Imunohemoterapia","4200-319",{"type":49,"coordinates":918},[911,912],{"lat":912,"lon":911},{"facility":921,"status":76,"city":922,"state":28,"zip":923,"country":924,"countryCode":925,"cosmosGeoPoint":926,"geoPoint":930,"contacts":28},"Institut Oncologic \"Prof. Dr. Ion Chiricuta\" Cluj Napoca","Cluj-Napoca","400015","Romania","RO",{"type":49,"coordinates":927},[928,929],23.6,46.76667,{"lat":929,"lon":928},{"facility":932,"status":76,"city":933,"state":28,"zip":934,"country":935,"countryCode":936,"cosmosGeoPoint":937,"geoPoint":941,"contacts":28},"King Faisal Specialist Hospital & Research Centre, Riyadh","Riyadh","12713","Saudi Arabia","SA",{"type":49,"coordinates":938},[939,940],46.72185,24.68773,{"lat":940,"lon":939},{"facility":943,"status":76,"city":944,"state":28,"zip":945,"country":946,"countryCode":947,"cosmosGeoPoint":948,"geoPoint":952,"contacts":28},"Clinical Centre of Serbia, Institute for Haematology","Belgrade","11000","Serbia","RS",{"type":49,"coordinates":949},[950,951],20.46513,44.80401,{"lat":951,"lon":950},{"facility":954,"status":96,"city":955,"state":28,"zip":956,"country":946,"countryCode":947,"cosmosGeoPoint":957,"geoPoint":961,"contacts":28},"Clinical Centre of Vojvodina","Novi Sad","21000",{"type":49,"coordinates":958},[959,960],19.83694,45.25167,{"lat":960,"lon":959},{"facility":963,"status":76,"city":964,"state":28,"zip":965,"country":966,"countryCode":967,"cosmosGeoPoint":968,"geoPoint":972,"contacts":28},"Univerzitna Nemocnica Martin","Martin","036 59","Slovakia","SK",{"type":49,"coordinates":969},[970,971],18.92399,49.06651,{"lat":971,"lon":970},{"facility":974,"status":76,"city":975,"state":28,"zip":976,"country":966,"countryCode":967,"cosmosGeoPoint":977,"geoPoint":981,"contacts":28},"Vseobecna nemocnica Rimavska Sobota","Rimavská Sobota","979 01",{"type":49,"coordinates":978},[979,980],20.02239,48.38284,{"lat":980,"lon":979},{"facility":983,"status":76,"city":984,"state":28,"zip":985,"country":966,"countryCode":967,"cosmosGeoPoint":986,"geoPoint":990,"contacts":28},"Vranovska nemocnica, a.s.","Vranov nad Topľou","09327",{"type":49,"coordinates":987},[988,989],21.68479,48.88836,{"lat":989,"lon":988},{"facility":992,"status":76,"city":993,"state":994,"zip":995,"country":996,"countryCode":997,"cosmosGeoPoint":998,"geoPoint":1002,"contacts":28},"Wits Bara Clinical Trial Site","Johannesburg","Gauteng","2013","South Africa","ZA",{"type":49,"coordinates":999},[1000,1001],28.04363,-26.20227,{"lat":1001,"lon":1000},{"facility":1004,"status":76,"city":1005,"state":994,"zip":1006,"country":996,"countryCode":997,"cosmosGeoPoint":28,"geoPoint":28,"contacts":28},"Charlotte Maxeke Johannesburg Academic Hospital","Parktown, Johannesburg","2193",{"facility":1008,"status":96,"city":1009,"state":28,"zip":1010,"country":1011,"countryCode":28,"cosmosGeoPoint":1012,"geoPoint":1016,"contacts":28},"Daejeon Eulji Medical Center, Eulji University","Daejeon","35233","South Korea",{"type":49,"coordinates":1013},[1014,1015],127.38493,36.34913,{"lat":1015,"lon":1014},{"facility":1008,"status":42,"city":1009,"state":28,"zip":1010,"country":1011,"countryCode":28,"cosmosGeoPoint":1018,"geoPoint":1020,"contacts":28},{"type":49,"coordinates":1019},[1014,1015],{"lat":1015,"lon":1014},{"facility":1022,"status":76,"city":1023,"state":28,"zip":1024,"country":1011,"countryCode":28,"cosmosGeoPoint":1025,"geoPoint":1029,"contacts":28},"Severance Hospital, Yonsei University Health System","Seoul","03722",{"type":49,"coordinates":1026},[1027,1028],126.9784,37.566,{"lat":1028,"lon":1027},{"facility":1022,"status":107,"city":1023,"state":28,"zip":1024,"country":1011,"countryCode":28,"cosmosGeoPoint":1031,"geoPoint":1033,"contacts":28},{"type":49,"coordinates":1032},[1027,1028],{"lat":1028,"lon":1027},{"facility":1035,"status":42,"city":1023,"state":28,"zip":1036,"country":1011,"countryCode":28,"cosmosGeoPoint":1037,"geoPoint":1039,"contacts":28},"Gangdong Kyung Hee University Hospital","05278",{"type":49,"coordinates":1038},[1027,1028],{"lat":1028,"lon":1027},{"facility":1041,"status":76,"city":1023,"state":28,"zip":1036,"country":1011,"countryCode":28,"cosmosGeoPoint":1042,"geoPoint":1044,"contacts":28},"Kyung Hee University Hospital at Gangdong",{"type":49,"coordinates":1043},[1027,1028],{"lat":1028,"lon":1027},{"facility":1046,"status":76,"city":1047,"state":28,"zip":1048,"country":1049,"countryCode":1050,"cosmosGeoPoint":1051,"geoPoint":1055,"contacts":28},"Hospital Vall d'Hebron","Barcelona","08035","Spain","ES",{"type":49,"coordinates":1052},[1053,1054],2.15899,41.38879,{"lat":1054,"lon":1053},{"facility":1057,"status":76,"city":1058,"state":28,"zip":1059,"country":1049,"countryCode":1050,"cosmosGeoPoint":28,"geoPoint":28,"contacts":28},"Hospital Sant Joan de Déu","Esplugues Llobregat","08950",{"facility":1061,"status":76,"city":1062,"state":28,"zip":1063,"country":1049,"countryCode":1050,"cosmosGeoPoint":1064,"geoPoint":1068,"contacts":28},"Hospital Universitario La Paz","Madrid","28046",{"type":49,"coordinates":1065},[1066,1067],-3.70256,40.4165,{"lat":1067,"lon":1066},{"facility":1070,"status":42,"city":1071,"state":28,"zip":1072,"country":1049,"countryCode":1050,"cosmosGeoPoint":1073,"geoPoint":1077,"contacts":28},"Hospital Carlos Haya","Málaga","29010",{"type":49,"coordinates":1074},[1075,1076],-4.42034,36.72016,{"lat":1076,"lon":1075},{"facility":1079,"status":76,"city":1071,"state":28,"zip":1072,"country":1049,"countryCode":1050,"cosmosGeoPoint":1080,"geoPoint":1082,"contacts":28},"Hospital Regional Universitario de Málaga",{"type":49,"coordinates":1081},[1075,1076],{"lat":1076,"lon":1075},{"facility":1084,"status":76,"city":1085,"state":28,"zip":1086,"country":1087,"countryCode":1088,"cosmosGeoPoint":1089,"geoPoint":1093,"contacts":28},"Universitätsklinik für Hämatologie","Bern","3010","Switzerland","CH",{"type":49,"coordinates":1090},[1091,1092],7.44744,46.94809,{"lat":1092,"lon":1091},{"facility":1095,"status":76,"city":1096,"state":28,"zip":1097,"country":1087,"countryCode":1088,"cosmosGeoPoint":1098,"geoPoint":1102,"contacts":28},"Pädiatrische Onkologie-Hämatologie","Lucerne","6000",{"type":49,"coordinates":1099},[1100,1101],8.30635,47.05048,{"lat":1101,"lon":1100},{"facility":1104,"status":76,"city":1105,"state":28,"zip":1106,"country":1087,"countryCode":1088,"cosmosGeoPoint":1107,"geoPoint":1111,"contacts":28},"Zentrum für Labormedizin","Sankt Gallen","9008",{"type":49,"coordinates":1108},[1109,1110],9.37477,47.42391,{"lat":1110,"lon":1109},{"facility":1113,"status":76,"city":1114,"state":28,"zip":1115,"country":1087,"countryCode":1088,"cosmosGeoPoint":1116,"geoPoint":1120,"contacts":28},"Universitätsspital Zürich - Klinik für Medizinische Onkologie und Hämatologie","Zurich","8091",{"type":49,"coordinates":1117},[1118,1119],8.55,47.36667,{"lat":1119,"lon":1118},{"facility":1122,"status":76,"city":1123,"state":28,"zip":1124,"country":1125,"countryCode":1126,"cosmosGeoPoint":1127,"geoPoint":1131,"contacts":28},"Chung Shan Medical University Hospital","Taichung","402","Taiwan","TW",{"type":49,"coordinates":1128},[1129,1130],120.6839,24.1469,{"lat":1130,"lon":1129},{"facility":1133,"status":76,"city":1123,"state":28,"zip":1134,"country":1125,"countryCode":1126,"cosmosGeoPoint":1135,"geoPoint":1137,"contacts":28},"Taichung Veterans General Hospital","407",{"type":49,"coordinates":1136},[1129,1130],{"lat":1130,"lon":1129},{"facility":1139,"status":76,"city":1140,"state":28,"zip":1141,"country":1125,"countryCode":1126,"cosmosGeoPoint":1142,"geoPoint":1146,"contacts":28},"National Taiwan University Hospital_main","Taipei","100",{"type":49,"coordinates":1143},[1144,1145],121.52639,25.05306,{"lat":1145,"lon":1144},{"facility":1148,"status":107,"city":1140,"state":28,"zip":1141,"country":1125,"countryCode":1126,"cosmosGeoPoint":1149,"geoPoint":1151,"contacts":28},"National Taiwan University Hospital",{"type":49,"coordinates":1150},[1144,1145],{"lat":1145,"lon":1144},{"facility":1153,"status":107,"city":1154,"state":1155,"zip":1156,"country":1157,"countryCode":28,"cosmosGeoPoint":1158,"geoPoint":1162,"contacts":28},"Gazi University","Ankara","Beşevler\u002FAnkara","06500","Turkey (Türkiye)",{"type":49,"coordinates":1159},[1160,1161],32.85427,39.91987,{"lat":1161,"lon":1160},{"facility":1164,"status":76,"city":1154,"state":1155,"zip":1156,"country":1157,"countryCode":28,"cosmosGeoPoint":1165,"geoPoint":1167,"contacts":28},"Gazi Üniversitesi Hastanesi- Hematoloji",{"type":49,"coordinates":1166},[1160,1161],{"lat":1161,"lon":1160},{"facility":1169,"status":42,"city":1170,"state":1170,"zip":1171,"country":1157,"countryCode":28,"cosmosGeoPoint":28,"geoPoint":28,"contacts":28},"Istanbul University Oncology Institute","Capa-ISTANBUL","34093",{"facility":1173,"status":76,"city":1170,"state":1170,"zip":1171,"country":1157,"countryCode":28,"cosmosGeoPoint":28,"geoPoint":28,"contacts":28},"İstanbul Üniversitesi İstanbul Tıp Fakültesi Hastanesi- Onkoloji Enstitüsü",{"facility":1175,"status":76,"city":1176,"state":1177,"zip":1178,"country":1157,"countryCode":28,"cosmosGeoPoint":1179,"geoPoint":1183,"contacts":28},"Akdeniz Üniversitesi Hastanesi- Hematoloji","Antalya","Konyaaltı\u002F Antalya","01010",{"type":49,"coordinates":1180},[1181,1182],30.69556,36.90812,{"lat":1182,"lon":1181},{"facility":1185,"status":76,"city":1186,"state":28,"zip":1187,"country":1157,"countryCode":28,"cosmosGeoPoint":1188,"geoPoint":1192,"contacts":28},"Acıbadem Adana Hastanesi-Hematoloji","Adana","01130",{"type":49,"coordinates":1189},[1190,1191],35.32531,36.98615,{"lat":1191,"lon":1190},{"facility":1194,"status":76,"city":1154,"state":28,"zip":1195,"country":1157,"countryCode":28,"cosmosGeoPoint":1196,"geoPoint":1198,"contacts":28},"Hacettepe Universitesi","06100",{"type":49,"coordinates":1197},[1160,1161],{"lat":1161,"lon":1160},{"facility":1200,"status":76,"city":1154,"state":28,"zip":1195,"country":1157,"countryCode":28,"cosmosGeoPoint":1201,"geoPoint":1203,"contacts":28},"Hacettepe Üniversitesi Hastanesi- Hematoloji",{"type":49,"coordinates":1202},[1160,1161],{"lat":1161,"lon":1160},{"facility":1205,"status":42,"city":1176,"state":28,"zip":1178,"country":1157,"countryCode":28,"cosmosGeoPoint":1206,"geoPoint":1208,"contacts":28},"Akdeniz Universitesi",{"type":49,"coordinates":1207},[1181,1182],{"lat":1182,"lon":1181},{"facility":1210,"status":42,"city":1211,"state":28,"zip":1212,"country":1157,"countryCode":28,"cosmosGeoPoint":28,"geoPoint":28,"contacts":28},"Ege Universitesi Tip Fakultesi","Bornova-IZMIR","35100",{"facility":1214,"status":76,"city":1211,"state":28,"zip":1212,"country":1157,"countryCode":28,"cosmosGeoPoint":28,"geoPoint":28,"contacts":28},"Ege Üniversitesi Hastanesi- Hematoloji",{"facility":1216,"status":76,"city":1217,"state":28,"zip":1218,"country":1157,"countryCode":28,"cosmosGeoPoint":1219,"geoPoint":1223,"contacts":28},"Trakya University","Edirne","22030",{"type":49,"coordinates":1220},[1221,1222],26.55597,41.67719,{"lat":1222,"lon":1221},{"facility":1225,"status":76,"city":1217,"state":28,"zip":1218,"country":1157,"countryCode":28,"cosmosGeoPoint":1226,"geoPoint":1228,"contacts":28},"Trakya Üniversitesi Tıp Fakültesi Hastanesi-Hematoloji",{"type":49,"coordinates":1227},[1221,1222],{"lat":1222,"lon":1221},{"facility":1230,"status":76,"city":1231,"state":28,"zip":1232,"country":1233,"countryCode":1234,"cosmosGeoPoint":1235,"geoPoint":1239,"contacts":28},"Belfast City Hospital","Belfast","BT9 78B","United Kingdom","UK",{"type":49,"coordinates":1236},[1237,1238],-5.92541,54.59682,{"lat":1238,"lon":1237},{"facility":1241,"status":76,"city":1242,"state":28,"zip":1243,"country":1233,"countryCode":1234,"cosmosGeoPoint":1244,"geoPoint":1248,"contacts":28},"University Hospital of Wales - Haemophilia","Cardiff","CF14 4XW",{"type":49,"coordinates":1245},[1246,1247],-3.18,51.48,{"lat":1247,"lon":1246},{"facility":1250,"status":76,"city":1251,"state":28,"zip":1252,"country":1233,"countryCode":1234,"cosmosGeoPoint":1253,"geoPoint":1257,"contacts":28},"Royal Free Haemophilia Comprehensive Care Center","London","NW3 2QG",{"type":49,"coordinates":1254},[1255,1256],-0.12574,51.50853,{"lat":1256,"lon":1255},{"facility":1259,"status":76,"city":1251,"state":28,"zip":1252,"country":1233,"countryCode":1234,"cosmosGeoPoint":1260,"geoPoint":1262,"contacts":28},"Royal Free Hospital - Haemophilia",{"type":49,"coordinates":1261},[1255,1256],{"lat":1256,"lon":1255},{"facility":1264,"status":76,"city":1251,"state":28,"zip":1265,"country":1233,"countryCode":1234,"cosmosGeoPoint":1266,"geoPoint":1268,"contacts":28},"Evelina London Children's Hospital - Haemophilia","SE1 7EH",{"type":49,"coordinates":1267},[1255,1256],{"lat":1256,"lon":1255},{"facility":1270,"status":76,"city":1251,"state":28,"zip":1265,"country":1233,"countryCode":1234,"cosmosGeoPoint":1271,"geoPoint":1273,"contacts":28},"St Thomas' Hospital - Haemostasis and Thrombosis Centre",{"type":49,"coordinates":1272},[1255,1256],{"lat":1256,"lon":1255},{"facility":1275,"status":76,"city":1276,"state":28,"zip":1277,"country":1233,"countryCode":1234,"cosmosGeoPoint":1278,"geoPoint":1282,"contacts":28},"Royal Hallamshire Hospital","Sheffield","S10 2JF",{"type":49,"coordinates":1279},[1280,1281],-1.4659,53.38297,{"lat":1281,"lon":1280},{"type":1284,"investigatorFullName":28,"investigatorTitle":28,"investigatorAffiliation":28,"oldNameTitle":28,"oldOrganization":28},"SPONSOR","100491907","phase-3-a-research-study-looking-at-long-term-treatment-with-mim8-in-people-with-haemophilia-a-100491907",false,"NCT05685238","A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A","Open-label, Long-term Safety and Efficacy Study of Mim8 in Participants With Haemophilia A With or Without Inhibitors","FRONTIER4","Arm 1 \\& 2:\n\nInclusion Criteria:\n\n1. Informed consent obtained before any study related activities. Study related activities are any procedures that are carried out as part of the study, including activities to determine suitability for the study.\n2. Male or female with diagnosis of congenital haemophilia A based on medical records.\n3. Ongoing participation in study NN7769-4513, NN7769-4514, NN7769-4516, or NN7769-4728 at the time of transfer. Participant should qualify either of the following criteria:\n\n   1. Participant from study NN7769-4513, who has participated in the extension part of the study for at least 12 weeks prior to enrolment in study NN7769-4532, or,\n   2. Participant has completed the end of treatment visit for study NN7769-4514, NN7769-4516 or NN7769-4728.\n4. Participant and\u002For participant's parent(s)\u002Fparticipant's Legally acceptable representative (LAR) willingness and ability to comply with scheduled visits and study procedures, including the completion of diary.\n\nExclusion Criteria:\n\n1. Any disorder, except for conditions associated with haemophilia A, which in the investigator's opinion might jeopardise participant's safety or compliance with the protocol.\n2. Participant who has discontinued or been withdrawn from studies NN7769-4513, NN7769-4514, NN7769-4516, or NN7769-4728.\n3. Previous participation in this study. Participation is defined as signed informed consent.\n4. Female who is pregnant, breast-feeding or intends to become pregnant.\n5. Female of child-bearing potential and not using a highly effective contraceptive method (highly effective contraceptive measures or as required by local regulation or practice).\n6. Participation (i.e., signed informed consent) in any interventional, clinical study (except from study NN7769-4513, NN7769-4514, NN7769-4516, or NN7769-4728) of an approved or non-approved investigational medicinal product.\n7. Any planned major surgery, during part 1 of the study.\n8. Mental incapacity, unwillingness to cooperate, or a language barrier precluding adequate understanding and cooperation.\n\nArm 3:\n\nInclusion criteria\n\n1. Informed consent obtained before any study-related activities. Study-related activities are any procedures that are carried out as part of the study, including activities to determine suitability for the study.\n2. Male or female with diagnosis of congenital severe haemophilia A (endogenous FVIII activity less than (\\\u003C) 1 percentage \\[%\\]) with or without FVIII inhibitors based on medical records.\n3. Aged \\\u003C1 year at the time of signing informed consent.\n4. Body weight greater than or equal to (≥) 3.2 kilograms at the time of signing informed consent.\n5. previously untreated patients (PUPs) or minimally treated patients (MTPs) (i.e., up to 5 days of exposure to haemophilia-related treatment such as plasma-derived FVIII, recombinant FVIII, fresh frozen plasma, cryoprecipitate, or whole blood products).\n6. Full-term pregnancy (gestational age ≥37 weeks).\n7. Participant's parent(s)\u002FLAR(s) willingness and ability to comply with scheduled visits and Arm 3 (infant) procedures, including the completion of diary and patient reported outcome (PRO) questionnaire.\n8. Participants \\\u003C3 months of age must show no signs of active intracranial haemorrhage at screening. This is confirmed by cranial ultrasound performed according to local practice and regardless of delivery method.\n9. Receipt of vitamin K prophylaxis (as per local standard practice).\n10. Availability of historical results in medical records for:\n\n    1. activated partial thromboplastin time (aPTT)\n    2. FVIII levels.\n11. Availability of historical results in medical records or pre-dose sample taken for:\n\n    1. fibrinogen\n    2. haematology parameters\n    3. biochemistry parameters (aspartate aminotransferase (AST) and\u002For alanine aminotransferase (ALT), bilirubin and creatinine).\n\nExclusion criteria\n\n1. Known or suspected hypersensitivity to trial product or related products.\n2. Previous participation in study 4532. Participation is defined as signed informed consent.\n3. Participation (i.e., signed informed consent) in any interventional clinical study with receipt of the last dose within 6 months (or 5 half-lives of the investigational medicinal product, whichever is shorter) before planned enrolment.\n4. Exposure to non-factor haemostatic products for bleeding prophylaxis within 6 months (or 5 half-lives of the medicinal product, whichever is shorter) before planned enrolment.\n5. Known congenital or acquired coagulation disorders other than haemophilia A.\n6. Other conditions (e.g., autoimmune disease) or laboratory abnormality that may increase the risk of bleeding or thrombosis, as evaluated by the investigator. Any disorder, except for conditions associated with haemophilia A, that in the investigator's opinion might jeopardise the participant's safety or compliance with the protocol.\n7. Lack of adequate parental\u002Flegally acceptable representative (LAR) support to enter accurately and timely information regarding treatment and bleeding episodes into an (electronic) diary.\n8. Previous or current treatment for thromboembolic disease (with the exception of previous catheter-associated thrombosis for which anti-thrombotic treatment is not currently ongoing) or signs of thromboembolic disease.\n9. Any planned major surgery, during part 1 of Arm 3 (infant). For definition of major surgery.\n10. Immune tolerance induction planned to take place after treatment initiation.\n11. Hepatic dysfunction defined as AST and\u002For ALT greater than (\\>) 3 times the upper limit of normal (ULN) combined with total bilirubin \\>1.5 times the ULN.\n12. Serum creatinine above 1.5 times the ULN.","ALL",{"count":1295,"type":1296},451,"ESTIMATED","INTERVENTIONAL",[1299],"PHASE3","This study is looking at how Mim8 works in people with haemophilia A, who either have inhibitors or do not have inhibitors. Mim8 is a new medicine that will be used to avoid bleeding episodes. Mim8 works by replacing the function of the missing clotting factor VIII (FVIII). The study will last for up to 5.5 years. The duration of the study depends on when the participant enrolled in this study. The study will end if Mim8 is approved and marketed in participant's country during the study, or the study will end in June 2028, whichever comes first. Participants will get up to 262 injections; the number of injections depends on how often participants will get injections and how long time participants take part in the study. While taking part in this study, there are some restrictions about what medicine participants can use. The study doctor will tell the participants more about this. In case the participants experience bleeds, these can be treated with additional haemostatic medicine as agreed with the study doctor. Female participants cannot take part if they are pregnant, breast-feeding or plan to get pregnant during the study period.",[1302,1303],"Haemophilia A","Haemophilia A With Inhibitors","2026-06-25",{"date":1306,"type":1307},"2026-06-30","ACTUAL",{"date":1309,"type":1307},"2023-02-13",{"date":1311,"type":1296},"2028-06-30",{"name":5,"class":6},152]