[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100527161":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":43,"centralContacts":47,"locations":56,"responsibleParty":139,"collaborators":31,"id":141,"slug":142,"hasResults":143,"nctId":144,"briefTitle":145,"officialTitle":146,"acronym":31,"eligibilityCriteria":147,"healthyVolunteers":143,"sex":148,"minAge":149,"maxAge":150,"enrollmentInfo":151,"targetDuration":31,"studyType":154,"phases":155,"briefSummary":157,"conditions":158,"keywords":165,"overallStatus":59,"whyStopped":31,"lastUpdateSubmitDate":172,"lastUpdatePostDateStruct":173,"startDateStruct":176,"completionDateStruct":178,"leadSponsor":180,"locationsCount":181},{"fullName":5,"class":6},"Memorial Sloan Kettering Cancer Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Participants with Breast Cancer","EXPERIMENTAL","Participants will have a diagnosis of breast cancer and may undergo axillary lymph node dissection.",[13,14,15,16,17],"Procedure: Immediate Lymphatic Reconstruction","Diagnostic Test: Volumetric arm measurements","Other: Lymphatic massage","Other: Range of motion exercises","Other: Compression garment use",[19,26,32,36,39],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","Immediate Lymphatic Reconstruction","Immediate Lymphatic Reconstruction will happen at the time of Axillary Lymph Node Dissection",[9],[25],"ILR",{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"DIAGNOSTIC_TEST","Volumetric arm measurements","Volumetric arm measurements will occur at each in-person postoperative visit time points.",[9],null,{"type":6,"name":33,"description":34,"armGroupLabels":35,"otherNames":31},"Lymphatic massage","Participants will begin self-directed lymphatic massage 24 to 48 h after surgery and will continue to do lymphatic massage 3 times a week for 3 months after surgery or until 3 months after any adjuvant treatments (chemotherapy, radiation, etc.) are completed",[9],{"type":6,"name":37,"description":34,"armGroupLabels":38,"otherNames":31},"Range of motion exercises",[9],{"type":6,"name":40,"description":41,"armGroupLabels":42,"otherNames":31},"Compression garment use","Participants will use compression garments 24 to 48 h after surgery and will continue daily use for at least 8 h a day for 3 months or until 3 months after any adjuvant treatments are completed",[9],[44],{"name":45,"affiliation":5,"role":46},"Michelle Coriddi, MD","PRINCIPAL_INVESTIGATOR",[48,52],{"name":45,"role":49,"phone":50,"phoneExt":31,"email":51},"CONTACT","646-608-8042","coriddim@mskcc.org",{"name":53,"role":49,"phone":54,"phoneExt":31,"email":55},"Babak Mahrara, MD","646-608-8085","mehrarab@MSKCC.ORG",[57,73,84,95,107,118,128],{"facility":58,"status":59,"city":60,"state":61,"zip":62,"country":63,"countryCode":64,"cosmosGeoPoint":65,"geoPoint":70,"contacts":71},"Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)","RECRUITING","Basking Ridge","New Jersey","07920","United States","US",{"type":66,"coordinates":67},"Point",[68,69],-74.54932,40.70621,{"lat":69,"lon":68},[72],{"name":45,"role":49,"phone":50,"phoneExt":31,"email":31},{"facility":74,"status":59,"city":75,"state":61,"zip":76,"country":63,"countryCode":64,"cosmosGeoPoint":77,"geoPoint":81,"contacts":82},"Memorial Sloan Kettering Monmouth (Limited Protocol Activities)","Middletown","07748",{"type":66,"coordinates":78},[79,80],-74.11709,40.39428,{"lat":80,"lon":79},[83],{"name":45,"role":49,"phone":50,"phoneExt":31,"email":31},{"facility":85,"status":59,"city":86,"state":61,"zip":87,"country":63,"countryCode":64,"cosmosGeoPoint":88,"geoPoint":92,"contacts":93},"Memorial Sloan Kettering Bergen (Limited Protocol Activities)","Montvale","07645",{"type":66,"coordinates":89},[90,91],-74.02292,41.04676,{"lat":91,"lon":90},[94],{"name":45,"role":49,"phone":50,"phoneExt":31,"email":31},{"facility":96,"status":59,"city":97,"state":98,"zip":99,"country":63,"countryCode":64,"cosmosGeoPoint":100,"geoPoint":104,"contacts":105},"Memorial Sloan Kettering Commack (Limited Protocol Activities)","Commack","New York","11725",{"type":66,"coordinates":101},[102,103],-73.29289,40.84288,{"lat":103,"lon":102},[106],{"name":45,"role":49,"phone":50,"phoneExt":31,"email":31},{"facility":108,"status":59,"city":109,"state":98,"zip":110,"country":63,"countryCode":64,"cosmosGeoPoint":111,"geoPoint":115,"contacts":116},"Memorial Sloan Kettering Westchester (Limited Protocol Activities)","Harrison","10604",{"type":66,"coordinates":112},[113,114],-73.71263,40.96899,{"lat":114,"lon":113},[117],{"name":45,"role":49,"phone":50,"phoneExt":31,"email":31},{"facility":119,"status":59,"city":98,"state":98,"zip":120,"country":63,"countryCode":64,"cosmosGeoPoint":121,"geoPoint":125,"contacts":126},"Memorial Sloan Kettering Cancer Center (All Protocol Activities)","10065",{"type":66,"coordinates":122},[123,124],-74.00597,40.71427,{"lat":124,"lon":123},[127],{"name":45,"role":49,"phone":50,"phoneExt":31,"email":31},{"facility":129,"status":59,"city":130,"state":98,"zip":131,"country":63,"countryCode":64,"cosmosGeoPoint":132,"geoPoint":136,"contacts":137},"Memorial Sloan Kettering Nassau (Limited Protocol Activities)","Uniondale","11553",{"type":66,"coordinates":133},[134,135],-73.59291,40.70038,{"lat":135,"lon":134},[138],{"name":45,"role":49,"phone":50,"phoneExt":31,"email":31},{"type":140,"investigatorFullName":31,"investigatorTitle":31,"investigatorAffiliation":31,"oldNameTitle":31,"oldOrganization":31},"SPONSOR","100527161","phase-3-a-study-of-a-comprehensive-prevention-program-to-reduce-lymphedema-after-axillary-lymph-node-dissection-in-people-with-breast-cancer-100527161",false,"NCT06144164","A Study of a Comprehensive Prevention Program to Reduce Lymphedema After Axillary Lymph Node Dissection in People With Breast Cancer","A Prospective Cohort Study of Patients Undergoing ALND for Treatment of Breast Cancer: The Efficacy of a Comprehensive Prevention Program in Decreasing the Incidence of Lymphedema and Improving Quality of Life","Inclusion Criteria:\n\n* Female sex\n* Diagnosis of breast cancer\n* Ages 18 to 75 years\n* Consented for unilateral ALND or for unilateral SLNB with possible ALND\n\nExclusion Criteria:\n\n* Male sex\n* Does not speak English\n* Does not fit into study garment\n* Axillary recurrence\n* History of ALND\n* Requirement of bilateral ALND for the treatment of breast cancer\n* Treatment with SLNB only\n* Known anaphylactic allergy to ICG dye used in ILR\n* Impaired decision-making capacity","FEMALE","18 Years","75 Years",{"count":152,"type":153},285,"ESTIMATED","INTERVENTIONAL",[156],"PHASE3","The purpose of this study to test whether a comprehensive program may help the lymph fluid to drain out of the arm and prevent lymphedema in participants with breast cancer.",[159,160,161,162,163,164],"Lymphedema","Lymphedema Arm","Lymphedema of Upper Arm","Breast Cancer","Breast Carcinoma","Female Breast Cancer",[166,167,159,160,161,168,169,170,5,171],"immediate lymphatic reconstruction","axillary lymph node dissection","Breast cancer","breast carcinoma","female breast cancer","23-303","2025-11-06",{"date":174,"type":175},"2025-11-10","ACTUAL",{"date":177,"type":175},"2023-11-16",{"date":179,"type":153},"2030-03-16",{"name":5,"class":6},7]