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Must have discontinued ARPI before randomization into the study\n* Have an eastern cooperative oncology group (ECOG) performance status of 0 to 1\n\nExclusion criteria:\n\n* Known history of either brain or leptomeningeal prostate cancer metastases\n* Participants with known breast cancer gene 1\u002F2 (BRCA 1\u002F2) mutations (germline or somatic) who have not received treatment with a poly (ADP-ribose) polymerase (PARP) inhibitor, unless not available or contraindicated\n* Prior or concurrent second malignancy (other than the disease under study) because the natural history or treatment could interfere with study endpoints\n* Received cytotoxic chemotherapy for prostate cancer in any setting\n* Received prior treatment with human kallikrein 2 (KLK-2) directed therapies","ALL","18 Years",{"count":1278,"type":1279},800,"ESTIMATED","INTERVENTIONAL",[1282],"PHASE3","The purpose of this study is to find out whether treatment with pasritamig and docetaxel prolongs radiographic progression free survival (rPFS) (the length of time from start of treatment until disease worsens as determined by scans) when compared to treatment with docetaxel in participants with metastatic castrate-resistant prostate cancer (mCRPC; a cancer of prostate, a male reproductive gland found below the bladder, that grows despite low levels of male hormones).",[1285],"Prostatic Neoplasms, Castration-Resistant","2026-06-04",{"date":1288,"type":1289},"2026-06-05","ACTUAL",{"date":1291,"type":1289},"2025-12-19",{"date":1293,"type":1279},"2029-07-20",{"name":5,"class":6},136]