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gender-specific growth chart for diagnosis of obesity) with at least 2 of the following predefined weight-related comorbidities: hypertension, prediabetes and hypertriglyceridemia.\n* Have history of at least 1 self-reported unsuccessful dietary effort to lose weight.\n* Are capable of giving signed informed consent by a legal representative or assent by a study participant (when applicable).\n\nExclusion Criteria:\n\n* Have undergone or plan to undergo a weight reduction procedure during the study, such as, but not limited to\n\n  * gastric bypass\n  * sleeve gastrectomy\n  * restrictive bariatric surgery, such as Lap-Band gastric banding, or\n  * any other procedure intended to result in weight reduction.\n* Have a self-reported, or by parent or legal guardian where applicable, decrease in body weight greater than 5 kg (11 lbs) within 90 days before screening irrespective of medical records\n* Have type 1 diabetes or history of ketoacidosis, or hyperosmolar state\n* Have type 2 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