[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100615127":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":33,"locations":41,"responsibleParty":566,"collaborators":11,"id":568,"slug":569,"hasResults":570,"nctId":571,"briefTitle":572,"officialTitle":573,"acronym":11,"eligibilityCriteria":574,"healthyVolunteers":570,"sex":575,"minAge":576,"maxAge":577,"enrollmentInfo":578,"targetDuration":11,"studyType":581,"phases":582,"briefSummary":584,"conditions":585,"keywords":11,"overallStatus":44,"whyStopped":11,"lastUpdateSubmitDate":587,"lastUpdatePostDateStruct":588,"startDateStruct":591,"completionDateStruct":593,"leadSponsor":595,"locationsCount":596},{"fullName":5,"class":6},"Bristol-Myers Squibb","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"KarXT","EXPERIMENTAL",null,[13],"Drug: KarXT",{"label":15,"type":16,"description":11,"interventionNames":17},"Placebo","PLACEBO_COMPARATOR",[18],"Other: KarXT Matching Placebo",[20,26],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"DRUG","Specified dose on specified days",[9],[25],"BMS-986510",{"type":27,"name":28,"description":22,"armGroupLabels":29,"otherNames":11},"OTHER","KarXT Matching Placebo",[15],[31],{"name":5,"affiliation":5,"role":32},"STUDY_DIRECTOR",[34,39],{"name":35,"role":36,"phone":37,"phoneExt":11,"email":38},"BMS Clinical Trials Contact Center www.BMSClinicalTrials.com","CONTACT","855-907-3286","Clinical.Trials@bms.com",{"name":40,"role":36,"phone":11,"phoneExt":11,"email":11},"First line of the email MUST contain NCT # and Site #.",[42,60,73,86,98,110,123,136,150,162,174,188,201,213,226,239,252,265,277,289,301,314,322,331,339,348,357,372,385,397,409,419,433,446,459,467,479,486,500,509,518,530,542,554],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Advanced Research Center Inc.","RECRUITING","Anaheim","California","92805","United States","US",{"type":51,"coordinates":52},"Point",[53,54],-117.9145,33.83529,{"lat":54,"lon":53},[57],{"name":58,"role":36,"phone":59,"phoneExt":11,"email":11},"Steven Macina, Site 0077","714-999-6688",{"facility":61,"status":44,"city":62,"state":46,"zip":63,"country":48,"countryCode":49,"cosmosGeoPoint":64,"geoPoint":68,"contacts":69},"Inland Psychiatric Medical Group.","Chino","91710",{"type":51,"coordinates":65},[66,67],-117.68894,34.01223,{"lat":67,"lon":66},[70],{"name":71,"role":36,"phone":72,"phoneExt":11,"email":11},"Nandita Puchakayala, Site 0058","909-488-9116",{"facility":74,"status":75,"city":76,"state":46,"zip":77,"country":48,"countryCode":49,"cosmosGeoPoint":78,"geoPoint":82,"contacts":83},"Local Institution - 0024","NOT_YET_RECRUITING","Culver City","90230",{"type":51,"coordinates":79},[80,81],-118.39647,34.02112,{"lat":81,"lon":80},[84],{"name":85,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0024",{"facility":87,"status":75,"city":88,"state":46,"zip":89,"country":48,"countryCode":49,"cosmosGeoPoint":90,"geoPoint":94,"contacts":95},"Local Institution - 0083","Redlands","92373",{"type":51,"coordinates":91},[92,93],-117.18254,34.05557,{"lat":93,"lon":92},[96],{"name":97,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0083",{"facility":99,"status":75,"city":100,"state":46,"zip":101,"country":48,"countryCode":49,"cosmosGeoPoint":102,"geoPoint":106,"contacts":107},"Local Institution - 0089","San Francisco","94158",{"type":51,"coordinates":103},[104,105],-122.41942,37.77493,{"lat":105,"lon":104},[108],{"name":109,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0089",{"facility":111,"status":75,"city":112,"state":113,"zip":114,"country":48,"countryCode":49,"cosmosGeoPoint":115,"geoPoint":119,"contacts":120},"Local Institution - 0119","Hollywood","Florida","33024",{"type":51,"coordinates":116},[117,118],-80.14949,26.0112,{"lat":118,"lon":117},[121],{"name":122,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0119",{"facility":124,"status":44,"city":125,"state":113,"zip":126,"country":48,"countryCode":49,"cosmosGeoPoint":127,"geoPoint":131,"contacts":132},"Apg Research, Llc","Orlando","32803",{"type":51,"coordinates":128},[129,130],-81.37924,28.53834,{"lat":130,"lon":129},[133],{"name":134,"role":36,"phone":135,"phoneExt":11,"email":11},"Morteza Nadjafi, Site 0032","407-423-7149",{"facility":137,"status":44,"city":138,"state":139,"zip":140,"country":48,"countryCode":49,"cosmosGeoPoint":141,"geoPoint":145,"contacts":146},"Atlanta Center for Medical Research","Atlanta","Georgia","30331",{"type":51,"coordinates":142},[143,144],-84.38798,33.749,{"lat":144,"lon":143},[147],{"name":148,"role":36,"phone":149,"phoneExt":11,"email":11},"Elyssa Barron, Site 0057","404-881-5800",{"facility":151,"status":44,"city":152,"state":139,"zip":153,"country":48,"countryCode":49,"cosmosGeoPoint":154,"geoPoint":158,"contacts":159},"Salveo Integrative Health - Lawrenceville","Lawrenceville","30046",{"type":51,"coordinates":155},[156,157],-83.98796,33.95621,{"lat":157,"lon":156},[160],{"name":161,"role":36,"phone":11,"phoneExt":11,"email":11},"Shahzad Hashmi, Site 0106",{"facility":163,"status":44,"city":164,"state":139,"zip":165,"country":48,"countryCode":49,"cosmosGeoPoint":166,"geoPoint":170,"contacts":171},"Denali Health Atlanta, LLC","Stone Mountain","30083",{"type":51,"coordinates":167},[168,169],-84.1702,33.80816,{"lat":169,"lon":168},[172],{"name":173,"role":36,"phone":11,"phoneExt":11,"email":11},"Maria Johnson, Site 0039",{"facility":175,"status":44,"city":176,"state":177,"zip":178,"country":48,"countryCode":49,"cosmosGeoPoint":179,"geoPoint":183,"contacts":184},"EmVenio Research Center - Prime Healthcare","Chicago","Illinois","60622",{"type":51,"coordinates":180},[181,182],-87.65005,41.85003,{"lat":182,"lon":181},[185],{"name":186,"role":36,"phone":187,"phoneExt":11,"email":11},"Mitchell Glaser, Site 0044","773-620-2995",{"facility":189,"status":75,"city":190,"state":191,"zip":192,"country":48,"countryCode":49,"cosmosGeoPoint":193,"geoPoint":197,"contacts":198},"Local Institution - 0076","Boston","Massachusetts","02115",{"type":51,"coordinates":194},[195,196],-71.05977,42.35843,{"lat":196,"lon":195},[199],{"name":200,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0076",{"facility":202,"status":75,"city":203,"state":191,"zip":204,"country":48,"countryCode":49,"cosmosGeoPoint":205,"geoPoint":209,"contacts":210},"Local Institution - 0059","Worcester","01608",{"type":51,"coordinates":206},[207,208],-71.80229,42.26259,{"lat":208,"lon":207},[211],{"name":212,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0059",{"facility":214,"status":75,"city":215,"state":216,"zip":217,"country":48,"countryCode":49,"cosmosGeoPoint":218,"geoPoint":222,"contacts":223},"Local Institution - 0061","Great Neck","New York","11021",{"type":51,"coordinates":219},[220,221],-73.72846,40.80066,{"lat":221,"lon":220},[224],{"name":225,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0061",{"facility":227,"status":44,"city":228,"state":229,"zip":230,"country":48,"countryCode":49,"cosmosGeoPoint":231,"geoPoint":235,"contacts":236},"University of Cincinnati Dept of Psychiatry and Behavioral Neuroscience","Cincinnati","Ohio","45219",{"type":51,"coordinates":232},[233,234],-84.51439,39.12711,{"lat":234,"lon":233},[237],{"name":238,"role":36,"phone":11,"phoneExt":11,"email":11},"Melissa DelBello, Site 0051",{"facility":240,"status":75,"city":241,"state":242,"zip":243,"country":48,"countryCode":49,"cosmosGeoPoint":244,"geoPoint":248,"contacts":249},"Local Institution - 0113","Nashville","Tennessee","37212",{"type":51,"coordinates":245},[246,247],-86.78444,36.16589,{"lat":247,"lon":246},[250],{"name":251,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0113",{"facility":253,"status":75,"city":254,"state":255,"zip":256,"country":48,"countryCode":49,"cosmosGeoPoint":257,"geoPoint":261,"contacts":262},"Local Institution - 0046","Garland","Texas","75043",{"type":51,"coordinates":258},[259,260],-96.63888,32.91262,{"lat":260,"lon":259},[263],{"name":264,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0046",{"facility":266,"status":75,"city":267,"state":255,"zip":268,"country":48,"countryCode":49,"cosmosGeoPoint":269,"geoPoint":273,"contacts":274},"Local Institution - 0120","Houston","77043",{"type":51,"coordinates":270},[271,272],-95.36327,29.76328,{"lat":272,"lon":271},[275],{"name":276,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0120",{"facility":278,"status":75,"city":279,"state":255,"zip":280,"country":48,"countryCode":49,"cosmosGeoPoint":281,"geoPoint":285,"contacts":286},"Local Institution - 0118","Plano","75093",{"type":51,"coordinates":282},[283,284],-96.69889,33.01984,{"lat":284,"lon":283},[287],{"name":288,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0118",{"facility":290,"status":75,"city":291,"state":255,"zip":292,"country":48,"countryCode":49,"cosmosGeoPoint":293,"geoPoint":297,"contacts":298},"Local Institution - 0066","Spring","77381",{"type":51,"coordinates":294},[295,296],-95.41716,30.07994,{"lat":296,"lon":295},[299],{"name":300,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0066",{"facility":302,"status":75,"city":303,"state":304,"zip":305,"country":48,"countryCode":49,"cosmosGeoPoint":306,"geoPoint":310,"contacts":311},"Local Institution - 0050","Richmond","Virginia","23284",{"type":51,"coordinates":307},[308,309],-77.46026,37.55376,{"lat":309,"lon":308},[312],{"name":313,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0050",{"facility":315,"status":316,"city":317,"state":318,"zip":319,"country":320,"countryCode":321,"cosmosGeoPoint":11,"geoPoint":11,"contacts":11},"Local Institution - 0084","WITHDRAWN","Ciudad Autónoma de Buenos Aires","Buenos Aires","C1133AAH","Argentina","AR",{"facility":323,"status":316,"city":324,"state":318,"zip":325,"country":320,"countryCode":321,"cosmosGeoPoint":326,"geoPoint":330,"contacts":11},"Local Institution - 0085","La Plata","1900",{"type":51,"coordinates":327},[328,329],-57.95442,-34.92126,{"lat":329,"lon":328},{"facility":332,"status":316,"city":318,"state":11,"zip":333,"country":320,"countryCode":321,"cosmosGeoPoint":334,"geoPoint":338,"contacts":11},"Local Institution - 0036","C1405BOA",{"type":51,"coordinates":335},[336,337],-58.37723,-34.61315,{"lat":337,"lon":336},{"facility":340,"status":316,"city":341,"state":11,"zip":342,"country":320,"countryCode":321,"cosmosGeoPoint":343,"geoPoint":347,"contacts":11},"Local Institution - 0035","Córdoba","X5003DCE",{"type":51,"coordinates":344},[345,346],-64.18853,-31.40648,{"lat":346,"lon":345},{"facility":349,"status":316,"city":350,"state":11,"zip":351,"country":320,"countryCode":321,"cosmosGeoPoint":352,"geoPoint":356,"contacts":11},"Local Institution - 0102","Santiago del Estero","4200",{"type":51,"coordinates":353},[354,355],-64.26285,-27.80047,{"lat":355,"lon":354},{"facility":358,"status":75,"city":359,"state":360,"zip":361,"country":362,"countryCode":363,"cosmosGeoPoint":364,"geoPoint":368,"contacts":369},"Local Institution - 0109","Bello","Antioquia","051053","Colombia","CO",{"type":51,"coordinates":365},[366,367],-75.55795,6.33732,{"lat":367,"lon":366},[370],{"name":371,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0109",{"facility":373,"status":75,"city":374,"state":375,"zip":376,"country":362,"countryCode":363,"cosmosGeoPoint":377,"geoPoint":381,"contacts":382},"Local Institution - 0009","Pereira","Risaralda Department","660003",{"type":51,"coordinates":378},[379,380],-75.69488,4.81428,{"lat":380,"lon":379},[383],{"name":384,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0009",{"facility":386,"status":75,"city":387,"state":11,"zip":388,"country":362,"countryCode":363,"cosmosGeoPoint":389,"geoPoint":393,"contacts":394},"Local Institution - 0001","Barranquilla","080020",{"type":51,"coordinates":390},[391,392],-74.78132,10.96854,{"lat":392,"lon":391},[395],{"name":396,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0001",{"facility":398,"status":75,"city":399,"state":11,"zip":400,"country":362,"countryCode":363,"cosmosGeoPoint":401,"geoPoint":405,"contacts":406},"Local Institution - 0020","Bogotá","111166",{"type":51,"coordinates":402},[403,404],-74.08175,4.60971,{"lat":404,"lon":403},[407],{"name":408,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0020",{"facility":410,"status":75,"city":411,"state":412,"zip":413,"country":414,"countryCode":415,"cosmosGeoPoint":11,"geoPoint":11,"contacts":416},"Local Institution - 0075","Chikugo-Shi","Fukuoka","833-0041","Japan","JP",[417],{"name":418,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0075",{"facility":420,"status":44,"city":421,"state":422,"zip":423,"country":414,"countryCode":415,"cosmosGeoPoint":424,"geoPoint":428,"contacts":429},"Goryokai Medical Corporation - Goryokai Hospital","Sapporo","Hokkaido","002-8029",{"type":51,"coordinates":425},[426,427],141.35,43.06667,{"lat":427,"lon":426},[430],{"name":431,"role":36,"phone":432,"phoneExt":11,"email":11},"Kimihiro Nakajima, Site 0073","+81-11-771-5660",{"facility":434,"status":75,"city":435,"state":436,"zip":437,"country":414,"countryCode":415,"cosmosGeoPoint":438,"geoPoint":442,"contacts":443},"Local Institution - 0025","Zentsujichó","Kagawa-ken","765-8507",{"type":51,"coordinates":439},[440,441],133.77791,34.22699,{"lat":441,"lon":440},[444],{"name":445,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0025",{"facility":447,"status":75,"city":448,"state":449,"zip":450,"country":414,"countryCode":415,"cosmosGeoPoint":451,"geoPoint":455,"contacts":456},"Local Institution - 0062","Miyakonojō","Miyazaki","885-0093",{"type":51,"coordinates":452},[453,454],131.06667,31.73333,{"lat":454,"lon":453},[457],{"name":458,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0062",{"facility":460,"status":75,"city":461,"state":462,"zip":463,"country":414,"countryCode":415,"cosmosGeoPoint":11,"geoPoint":11,"contacts":464},"Local Institution - 0086","Bunkyo-ku","Tokyo","113-8431",[465],{"name":466,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0086",{"facility":468,"status":75,"city":469,"state":462,"zip":470,"country":414,"countryCode":415,"cosmosGeoPoint":471,"geoPoint":475,"contacts":476},"Local Institution - 0056","Ōta-ku","1438541",{"type":51,"coordinates":472},[473,474],139.71605,35.56126,{"lat":474,"lon":473},[477],{"name":478,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0056",{"facility":480,"status":75,"city":481,"state":11,"zip":482,"country":414,"countryCode":415,"cosmosGeoPoint":11,"geoPoint":11,"contacts":483},"Local Institution - 0063","Yokohama, Kanagawa","213-8507",[484],{"name":485,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0063",{"facility":487,"status":75,"city":488,"state":488,"zip":489,"country":490,"countryCode":491,"cosmosGeoPoint":492,"geoPoint":496,"contacts":497},"Local Institution - 0029","Bucharest","041914","Romania","RO",{"type":51,"coordinates":493},[494,495],26.10626,44.43225,{"lat":495,"lon":494},[498],{"name":499,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0029",{"facility":501,"status":75,"city":488,"state":11,"zip":502,"country":490,"countryCode":491,"cosmosGeoPoint":503,"geoPoint":505,"contacts":506},"Local Institution - 0040","021056",{"type":51,"coordinates":504},[494,495],{"lat":495,"lon":494},[507],{"name":508,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0040",{"facility":510,"status":75,"city":488,"state":11,"zip":511,"country":490,"countryCode":491,"cosmosGeoPoint":512,"geoPoint":514,"contacts":515},"Local Institution - 0042","031871",{"type":51,"coordinates":513},[494,495],{"lat":495,"lon":494},[516],{"name":517,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0042",{"facility":519,"status":75,"city":520,"state":11,"zip":521,"country":490,"countryCode":491,"cosmosGeoPoint":522,"geoPoint":526,"contacts":527},"Local Institution - 0031","Cluj-Napoca","400370",{"type":51,"coordinates":523},[524,525],23.6,46.76667,{"lat":525,"lon":524},[528],{"name":529,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0031",{"facility":531,"status":75,"city":532,"state":11,"zip":533,"country":490,"countryCode":491,"cosmosGeoPoint":534,"geoPoint":538,"contacts":539},"Local Institution - 0008","Iași","700282",{"type":51,"coordinates":535},[536,537],27.6,47.16667,{"lat":537,"lon":536},[540],{"name":541,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0008",{"facility":543,"status":75,"city":544,"state":11,"zip":545,"country":490,"countryCode":491,"cosmosGeoPoint":546,"geoPoint":550,"contacts":551},"Local Institution - 0030","Sibiu","550082",{"type":51,"coordinates":547},[548,549],24.15,45.8,{"lat":549,"lon":548},[552],{"name":553,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0030",{"facility":555,"status":75,"city":556,"state":11,"zip":557,"country":490,"countryCode":491,"cosmosGeoPoint":558,"geoPoint":562,"contacts":563},"Local Institution - 0038","Timișoara","300329",{"type":51,"coordinates":559},[560,561],21.22571,45.75372,{"lat":561,"lon":560},[564],{"name":565,"role":36,"phone":11,"phoneExt":11,"email":11},"Site 0038",{"type":567,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100615127","phase-3-a-study-to-evaluate-the-efficacy-and-safety-of-karxt-for-the-treatment-of-schizophrenia-in-adolescents-emergent-teen-100615127",false,"NCT07288567","A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)","A Phase 3 Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (13 to 17 Years of Age)","Inclusion Criteria:\n\n* Diagnosis of schizophrenia as defined by the The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition,Text Revision (DSM-5-TR) criteria, confirmed by the Kiddie Schedule for Affective Disorders and Schizophrenia-Present and Lifetime version (K-SADS-PL) and experiencing symptoms of psychosis at screening (Visit 1).\n* PANSS total score of at least 70 at screening (Visit 1) and randomization (Visit 2).\n* Participant has a CGI-S score of ≥ 4 at screening (Visit 1) and randomization (Visit 2).\n\nExclusion Criteria:\n\n* Any primary DSM-5-TR disorder other than schizophrenia within 12 months before screening.\n* History or presence of clinically significant cardiovascular, pulmonary, hepatic impairment, renal, hematologic, GI, endocrine, immunologic, dermatologic, neurologic, or oncologic disease or any other condition that, in the opinion of the investigator, would jeopardize the safety of the participant or the validity of the study results.\n* All grades of hepatic impairment (mild \\[Child-Pugh Class A\\], moderate \\[Child-Pugh Class B\\], and severe \\[Child-Pugh Class C\\]). Participants with known intellectual disability defined as an IQ less than 70; or, either clinical evidence or known social or school history indicative of intellectual disability.\n* Any neurological disorder, except for Tourette's Syndrome.\n* Participants who have either a systolic blood pressure (sBP) or diastolic blood pressure (dBP) meeting criteria for stage 2 HTN, regardless of the presence or absence of symptoms.\n* Other protocol-defined Inclusion\u002FExclusion criteria apply.","ALL","13 Years","17 Years",{"count":579,"type":580},166,"ESTIMATED","INTERVENTIONAL",[583],"PHASE3","The purpose of this study is to evaluate the efficacy and safety of KarXT for treatment of Schizophrenia in adolescents.",[586],"Schizophrenia","2026-06-29",{"date":589,"type":590},"2026-06-30","ACTUAL",{"date":592,"type":590},"2026-01-29",{"date":594,"type":580},"2029-12-18",{"name":5,"class":6},44]