[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639784":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":29,"centralContacts":36,"locations":42,"responsibleParty":58,"collaborators":29,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":29,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":29,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":79,"overallStatus":45,"whyStopped":29,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Control","ACTIVE_COMPARATOR","The patients will receive 20ml plain bupivacaine (0.125%) in the caudal block",[13],"Drug: Group C (plain bupivacaine (0.125%))",{"label":15,"type":10,"description":16,"interventionNames":17},"Dexmedetomidine","The patients will receive 20ml plain bupivacaine (0.125%) + 2μg\u002Fkg dexmedetomidine in the caudal block",[18],"Drug: Group D (plain bupivacaine (0.125%) + 2μg\u002Fkg dexmedetomidine)",{"label":20,"type":10,"description":21,"interventionNames":22},"Ketamine","The patients will receive 20ml plain bupivacaine (0.125%) + 1mg\u002Fkg ketamine in the caudal block",[23],"Drug: Group K (plain bupivacaine (0.125%) + 1mg\u002Fkg ketamine)",[25,30,33],{"type":26,"name":27,"description":11,"armGroupLabels":28,"otherNames":29},"DRUG","Group C (plain bupivacaine (0.125%))",[9],null,{"type":26,"name":31,"description":16,"armGroupLabels":32,"otherNames":29},"Group D (plain bupivacaine (0.125%) + 2μg\u002Fkg dexmedetomidine)",[15],{"type":26,"name":34,"description":21,"armGroupLabels":35,"otherNames":29},"Group K (plain bupivacaine (0.125%) + 1mg\u002Fkg ketamine)",[20],[37],{"name":38,"role":39,"phone":40,"phoneExt":29,"email":41},"Salma Ayman Abdulazeem, MSc","CONTACT","+201285665828","Salmaaymen0103389@med.asu.edu.eg",[43],{"facility":44,"status":45,"city":46,"state":29,"zip":29,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Ain Shams University hospitals","RECRUITING","Cairo","Egypt","EG",{"type":50,"coordinates":51},"Point",[52,53],31.24967,30.06263,{"lat":53,"lon":52},[56],{"name":57,"role":39,"phone":40,"phoneExt":29,"email":41},"Dr. Salma Ayman, MSc.",{"type":59,"investigatorFullName":29,"investigatorTitle":29,"investigatorAffiliation":29,"oldNameTitle":29,"oldOrganization":29},"SPONSOR","100639784","phase-3-adding-dexmedetomidine-versus-ketamine-to-bupivacaine-in-fluoroscopy-guided-caudal-analgesia-for-lumbosacral-surgeries-100639784",false,"NCT07573969","Adding Dexmedetomidine Versus Ketamine to Bupivacaine in Fluoroscopy Guided Caudal Analgesia for Lumbosacral Surgeries","Effect of Adding Dexmedetomidine Versus Ketamine to Bupivacaine in Fluoroscopy Guided Caudal Analgesia for Lumbosacral Surgeries Under General Anaesthesia; a Randomised Controlled Double Blinded Study","Inclusion Criteria:\n\n* Age 21-60 years.\n* Sex: Both sexes.\n* American Society of Anesthesiologists (ASA) Physical Status Class-I and II.\n* Scheduled for lumbosacral surgery under General Anesthesia.\n\nExclusion Criteria:\n\n* Declining to give written informed consent or patients with significant cognitive dysfunction that hinders informed consent.\n* History of allergy to the medications used in the study.\n* Contraindications to regional anesthesia (including coagulopathy and local infection).\n* History of recent analgesic intake or abuse.\n* Pregnancy or lactating mothers.","ALL","21 Years","60 Years",{"count":71,"type":72},72,"ESTIMATED","INTERVENTIONAL",[75],"PHASE3","This study will evaluate the effect of adding dexmedetomidine to bupivacaine compared to ketamine in the caudal block on perioperative analgesia in patients undergoing lumbosacral surgeries under general anesthesia.",[78],"Perioperative Analgesia",[80,81,82,83,84],"Caudal analgesia","Adult caudal blocks","Lumbosacral surgeries","Caudal ketamine","Caudal dexmedetomidine","2026-05-05",{"date":87,"type":88},"2026-05-07","ACTUAL",{"date":90,"type":72},"2026-05",{"date":92,"type":72},"2027-05",{"name":5,"class":6},1]