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Inclusion criteria will include absolute neutrophils count ≥1.5 x 109\u002FL, platelets ≥100 x 10\u002FL, serum bilirubin ≤ 2.0 x upper limit of normal (ULN), calculated creatinine clearance ≥50 mL\u002Fmin and alanine aminotransferase (ALT), aspartate aminotransferase (AST) and alkaline phosphatase ≤ 2.5 x ULN.\n* Patients of child-bearing potential were obligated to use an approved contraceptive method during and for 3 months after the study;\n* Agree with research procedures, by signing the Informed Consent Form (ICF).\n\nExclusion Criteria:\n\n* Previous cervical cancer or other malignancies,\n* Pregnant women,\n* Inability to perform concurrent cisplatin based-chemoradiotherapy.\n* Tumors containing different HPV genotypes\n* Absence of anatomopathological examination to prove the diagnosis and\u002For staging examinations.","FEMALE","18 Years","70 Years",{"count":468,"type":469},365,"ESTIMATED","INTERVENTIONAL",[472],"PHASE3","This study hypothesizes that patients who persist with cell-free human papillomavirus deoxyribonucleic acid (cfHPV-DNA) plasma expression at the end of standard treatment, can derive the benefit of using adjuvant chemotherapy in locally advanced cervical cancer (CC). 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