[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100498156":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":35,"locations":44,"responsibleParty":85,"collaborators":87,"id":91,"slug":92,"hasResults":93,"nctId":94,"briefTitle":95,"officialTitle":95,"acronym":24,"eligibilityCriteria":96,"healthyVolunteers":93,"sex":97,"minAge":98,"maxAge":24,"enrollmentInfo":99,"targetDuration":24,"studyType":102,"phases":103,"briefSummary":105,"conditions":106,"keywords":109,"overallStatus":67,"whyStopped":24,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":122},{"fullName":5,"class":6},"Yale University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"LGBTQ-affirmative CBT","EXPERIMENTAL","Individuals assigned to LGBTQ-affirmative cognitive behavioral therapy will receive 16 weekly individually-delivered sessions, directly after baseline assessment, delivered via telehealth. Based on the Unified Protocol, sessions will address minority stress mechanisms underlying sexual and gender minority mental health disparities.",[13],"Behavioral: LGBTQ-affirmative CBT",{"label":15,"type":10,"description":16,"interventionNames":17},"ABFT-SGM","Individuals assigned to attachment-based family therapy for sexual and gender minorities will receive a 16-session sequence of family-based therapy delivered via telehealth. This sequence will include sessions with sexual and\u002For gender minority adult children alone, adult children and parent(s), and parent(s) alone. Sessions will address the quality parent-child relationship in relation to child sexual orientation and gender identity to target mental health disparities.",[18],"Behavioral: ABFT-SGM",[20,25],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL","16-session LGBTQ-affirmative psychotherapy using cognitive behavioral techniques",[9],null,{"type":21,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"16-session attachment-based family therapy for sexual and gender minority young adults and their nonaccepting parents",[15],[29,32],{"name":30,"affiliation":5,"role":31},"John E Pachankis, PhD","PRINCIPAL_INVESTIGATOR",{"name":33,"affiliation":34,"role":31},"Gary M Diamond, PhD","Ben-Gurion University of the Negev",[36,40],{"name":30,"role":37,"phone":38,"phoneExt":24,"email":39},"CONTACT","646-429-9407","john.pachankis@yale.edu",{"name":41,"role":37,"phone":42,"phoneExt":24,"email":43},"Danielle M Chiaramonte, PhD","708-334-8331","danielle.chiaramonte@yale.edu",[45,65],{"facility":46,"status":47,"city":48,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Yale LGBTQ Mental Health Initiative with the Yale School of Public Health Office","NOT_YET_RECRUITING","New York","10001","United States","US",{"type":53,"coordinates":54},"Point",[55,56],-74.00597,40.71427,{"lat":56,"lon":55},[59,60,64],{"name":41,"role":37,"phone":42,"phoneExt":24,"email":43},{"name":61,"role":37,"phone":62,"phoneExt":24,"email":63},"Benjamin E Eisenstadt, BA","347-633-0610","ben.eisenstadt@yale.edu",{"name":30,"role":31,"phone":24,"phoneExt":24,"email":24},{"facility":66,"status":67,"city":68,"state":24,"zip":69,"country":70,"countryCode":71,"cosmosGeoPoint":72,"geoPoint":76,"contacts":77},"Ben-Gurion University Psychotherapy Research Lab","RECRUITING","Beersheba","84105","Israel","IL",{"type":53,"coordinates":73},[74,75],34.7913,31.25181,{"lat":75,"lon":74},[78,81,84],{"name":33,"role":37,"phone":79,"phoneExt":24,"email":80},"267-388-9393","gdiamond@bgu.ac.il",{"name":82,"role":37,"phone":24,"phoneExt":24,"email":83},"Noam Aiziczon","noamaizi@post.bgu.ac.il",{"name":33,"role":31,"phone":24,"phoneExt":24,"email":24},{"type":86,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR",[88,89],{"name":34,"class":6},{"name":90,"class":6},"Israel Science Foundation","100498156","phase-3-affirmative-family-and-individual-psychotherapy-for-sexual-and-gender-minority-adults-and-their-nonaccepting-parents-100498156",false,"NCT05766592","Affirmative Family and Individual Psychotherapy for Sexual and Gender Minority Adults and Their Nonaccepting Parents","Inclusion Criteria:\n\n* be 20 and older\n* be fluent in English\n* self-identify as lesbian, bisexual, queer, pansexual, or other non-heterosexual identity\n* currently experience elevated depressive or anxiety symptoms (screened initially using a cutoff of ≥ 2.5 on the Brief Symptom Inventory-4 and further confirmed by the BDI and BAI).\n* report at least moderate levels of parental rejection or low levels of parental acceptance, as measured using the PARSOS.\n* have at least one rejecting\u002Fnonaccepting parent that agrees to participate in the therapy.\n* live in New York State, Pennsylvania, Connecticut, or Israel.\n\nExclusion Criteria:\n\n* report current mental health treatment ≥1 day\u002Fmonth (except for medication management ≤1 day\u002Fweek)\n* report beginning a new medication within the past 30 days\n* exhibit active psychosis or active mania, as assessed by the SCID-Psych Screen.\n* exhibit active suicidality or active homicidality, as assessed by the SIDAS\n* be currently legally mandated to attend treatment\n* demonstrate gross cognitive impairment, as assessed with the Telephone Interview for Cognitive Status\n* do not have a parent willing to participate","ALL","20 Years",{"count":100,"type":101},124,"ESTIMATED","INTERVENTIONAL",[104],"PHASE3","The purpose of this study is to assess the efficacy of an LGBTQ-affirmative individual cognitive behavioral psychotherapy (CBT) and LGBTQ-affirmative family therapy (attachment-based family therapy for sexual and gender minority young adults; ABFT-SGM) delivered via telehealth to a sample of sexual and gender minority adults with nonaccepting parent(s) in New York, Pennsylvania, Connecticut, and Israel. The investigators will assess whether both treatments are associated with significant decreases in depressive and anxiety symptoms. The investigators will also assess whether and how each treatment achieves reductions in mental health symptoms through specific mechanisms (e.g., rejection sensitivity, internalized stigma, emotion dysregulation, parental rejection and acceptance).",[107,108],"Mental Health Issue","Parent-Child Relations",[110,111,112],"LGBTQ","Cognitive Behavioral Therapy","Attachment-Based Family Therapy","2026-01-12",{"date":115,"type":116},"2026-01-13","ACTUAL",{"date":118,"type":116},"2024-08-13",{"date":120,"type":101},"2027-06-30",{"name":5,"class":6},2]