[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100511436":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":31,"locations":38,"responsibleParty":1540,"collaborators":18,"id":1542,"slug":1543,"hasResults":1544,"nctId":1545,"briefTitle":1546,"officialTitle":1547,"acronym":1548,"eligibilityCriteria":1549,"healthyVolunteers":1544,"sex":1550,"minAge":1551,"maxAge":1552,"enrollmentInfo":1553,"targetDuration":18,"studyType":1556,"phases":1557,"briefSummary":1559,"conditions":1560,"keywords":1562,"overallStatus":41,"whyStopped":18,"lastUpdateSubmitDate":1572,"lastUpdatePostDateStruct":1573,"startDateStruct":1576,"completionDateStruct":1578,"leadSponsor":1580,"locationsCount":1581},{"fullName":5,"class":6},"Novartis","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Investigational Arm: lutetium (177Lu) vipivotide tetraxetan (AAA617)","EXPERIMENTAL","All participants will be treated with Stereotactic Body Radiation Therapy (SBRT) to all metastatic lesions followed by a dose of 7.4 GBq (200 mCi) +\u002F- 10% of AAA617 which will be administered once every 6 weeks (1 cycle) for a planned 4 cycles.",[13],"Drug: AAA617",{"label":15,"type":16,"description":17,"interventionNames":18},"Control arm: observation (watchful waiting)","NO_INTERVENTION","All participants will be treated with Stereotactic Body Radiation Therapy (SBRT) to all metastatic lesions followed by observation only.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","AAA617","Stereotactic Body Radiation Therapy (SBRT) followed by AAA617 will be administered once every 6 weeks (1 cycle) for a planned 4 cycles to participants randomized to the Investigational arm",[9],[26],"(177Lu) vipivotide tetraxetan",[28],{"name":29,"affiliation":29,"role":30},"Novartis Pharmaceuticals","STUDY_DIRECTOR",[32,36],{"name":29,"role":33,"phone":34,"phoneExt":18,"email":35},"CONTACT","1-888-669-6682","novartis.email@novartis.com",{"name":29,"role":33,"phone":37,"phoneExt":18,"email":35},"+41613241111",[39,61,78,94,107,123,140,156,171,186,203,216,232,248,265,280,297,309,325,337,353,363,375,392,408,420,432,448,464,479,495,512,529,546,559,574,582,598,615,630,647,662,669,671,674,685,694,703,712,722,730,740,748,756,766,777,786,795,803,811,820,825,833,843,851,859,865,873,883,891,899,910,918,926,934,942,950,958,969,978,986,994,1002,1010,1018,1026,1036,1041,1049,1060,1068,1073,1083,1091,1099,1107,1115,1126,1135,1144,1153,1162,1171,1180,1188,1199,1208,1217,1226,1230,1238,1243,1248,1256,1264,1272,1283,1291,1301,1304,1314,1332,1341,1346,1356,1364,1372,1380,1391,1400,1409,1414,1422,1427,1435,1443,1453,1461,1469,1479,1484,1489,1497,1508,1517,1525,1533],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Highlands Oncology Group","RECRUITING","Fayetteville","Arkansas","72703","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-94.15743,36.06258,{"lat":51,"lon":50},[54,58],{"name":55,"role":33,"phone":56,"phoneExt":18,"email":57},"Tina Patrick","+1 479 878 7098","tpatrick@hogonc.com",{"name":59,"role":60,"phone":18,"phoneExt":18,"email":18},"Joseph Thaddeus Beck","PRINCIPAL_INVESTIGATOR",{"facility":62,"status":41,"city":63,"state":64,"zip":65,"country":45,"countryCode":46,"cosmosGeoPoint":66,"geoPoint":70,"contacts":71},"VA Greater LA Healthcare System","Los Angeles","California","90073",{"type":48,"coordinates":67},[68,69],-118.24368,34.05223,{"lat":69,"lon":68},[72,76],{"name":73,"role":33,"phone":74,"phoneExt":18,"email":75},"Samantha Tran","310-478-3711","Samantha.Tran@va.gov",{"name":77,"role":60,"phone":18,"phoneExt":18,"email":18},"Matthew Rettig",{"facility":79,"status":41,"city":80,"state":64,"zip":81,"country":45,"countryCode":46,"cosmosGeoPoint":82,"geoPoint":86,"contacts":87},"VA Palo Alto Health Care System","Palo Alto","94304-1207",{"type":48,"coordinates":83},[84,85],-122.14302,37.44188,{"lat":85,"lon":84},[88,92],{"name":89,"role":33,"phone":90,"phoneExt":18,"email":91},"Niko Del Mar","650-493-5000","niko.delmar@va.gov",{"name":93,"role":60,"phone":18,"phoneExt":18,"email":18},"Minal Vasanawala",{"facility":95,"status":41,"city":80,"state":64,"zip":96,"country":45,"countryCode":46,"cosmosGeoPoint":97,"geoPoint":99,"contacts":100},"Stanford University","94304",{"type":48,"coordinates":98},[84,85],{"lat":85,"lon":84},[101,105],{"name":102,"role":33,"phone":103,"phoneExt":18,"email":104},"Camellia Djebroun","605-498-6000","cdjebrou@stanford.edu",{"name":106,"role":60,"phone":18,"phoneExt":18,"email":18},"Mallika Marar",{"facility":108,"status":41,"city":109,"state":64,"zip":110,"country":45,"countryCode":46,"cosmosGeoPoint":111,"geoPoint":115,"contacts":116},"UCSF","San Francisco","94115",{"type":48,"coordinates":112},[113,114],-122.41942,37.77493,{"lat":114,"lon":113},[117,121],{"name":118,"role":33,"phone":119,"phoneExt":18,"email":120},"Brittany Liu","415-514-6241","brittany.liu@ucsf.edu",{"name":122,"role":60,"phone":18,"phoneExt":18,"email":18},"Steven Seyedin",{"facility":124,"status":41,"city":125,"state":126,"zip":127,"country":45,"countryCode":46,"cosmosGeoPoint":128,"geoPoint":132,"contacts":133},"Rocky Mountain Cancer Centers","Denver","Colorado","80218",{"type":48,"coordinates":129},[130,131],-104.9847,39.73915,{"lat":131,"lon":130},[134,138],{"name":135,"role":33,"phone":136,"phoneExt":18,"email":137},"Jennifer Hege","303-338-4876","jennifer.hege@usoncology.com",{"name":139,"role":60,"phone":18,"phoneExt":18,"email":18},"Allen Cohn",{"facility":141,"status":41,"city":142,"state":143,"zip":144,"country":45,"countryCode":46,"cosmosGeoPoint":145,"geoPoint":149,"contacts":150},"Cancer Specialists of North Florida","Jacksonville","Florida","32256",{"type":48,"coordinates":146},[147,148],-81.65565,30.33218,{"lat":148,"lon":147},[151,154],{"name":152,"role":33,"phone":18,"phoneExt":18,"email":153},"Bhaloo Desai","Bhaloo.Desai@CSNF.us",{"name":155,"role":60,"phone":18,"phoneExt":18,"email":18},"Richard Cassidy",{"facility":157,"status":41,"city":158,"state":143,"zip":159,"country":45,"countryCode":46,"cosmosGeoPoint":160,"geoPoint":164,"contacts":165},"Woodlands Medical Specialists","Pensacola","32503",{"type":48,"coordinates":161},[162,163],-87.21691,30.42131,{"lat":163,"lon":162},[166,169],{"name":167,"role":33,"phone":18,"phoneExt":18,"email":168},"Jacqueline Martin","jacqueline.martin@woodlandsmed.com",{"name":170,"role":60,"phone":18,"phoneExt":18,"email":18},"Michael Poiesz",{"facility":172,"status":41,"city":173,"state":174,"zip":175,"country":45,"countryCode":46,"cosmosGeoPoint":176,"geoPoint":180,"contacts":181},"Piedmont Healthcare","Atlanta","Georgia","30318",{"type":48,"coordinates":177},[178,179],-84.38798,33.749,{"lat":179,"lon":178},[182,184],{"name":183,"role":33,"phone":18,"phoneExt":18,"email":18},"Sharon Joseph",{"name":185,"role":60,"phone":18,"phoneExt":18,"email":18},"Adam Nowlan",{"facility":187,"status":41,"city":188,"state":189,"zip":190,"country":45,"countryCode":46,"cosmosGeoPoint":191,"geoPoint":195,"contacts":196},"University of Chicago","Chicago","Illinois","60637",{"type":48,"coordinates":192},[193,194],-87.65005,41.85003,{"lat":194,"lon":193},[197,201],{"name":198,"role":33,"phone":199,"phoneExt":18,"email":200},"Ashley Page","773-702-8582","apage99@bsd.uchicago.edu",{"name":202,"role":60,"phone":18,"phoneExt":18,"email":18},"Mohammed Atiq",{"facility":204,"status":41,"city":205,"state":189,"zip":206,"country":45,"countryCode":46,"cosmosGeoPoint":207,"geoPoint":211,"contacts":212},"The Cancer Institute of Alexian Brothers","Elk Grove","60007",{"type":48,"coordinates":208},[209,210],-87.94034,42.00725,{"lat":210,"lon":209},[213],{"name":214,"role":33,"phone":18,"phoneExt":18,"email":215},"Khalada Ahmad","khalada.ahmad@ascension.org",{"facility":217,"status":41,"city":218,"state":219,"zip":220,"country":45,"countryCode":46,"cosmosGeoPoint":221,"geoPoint":225,"contacts":226},"Unity Point Clinic","Des Moines","Iowa","50323",{"type":48,"coordinates":222},[223,224],-93.60911,41.60054,{"lat":224,"lon":223},[227,230],{"name":228,"role":33,"phone":18,"phoneExt":18,"email":229},"Tracy Sarin","tsarin@iora.org",{"name":231,"role":60,"phone":18,"phoneExt":18,"email":18},"Mark Kellerman",{"facility":233,"status":41,"city":234,"state":235,"zip":236,"country":45,"countryCode":46,"cosmosGeoPoint":237,"geoPoint":241,"contacts":242},"University of Kansas Hospital","Kansas City","Kansas","66160",{"type":48,"coordinates":238},[239,240],-94.62746,39.11417,{"lat":240,"lon":239},[243,246],{"name":244,"role":33,"phone":18,"phoneExt":18,"email":245},"Daniel Rivera","drivera3@kumc.edu",{"name":247,"role":60,"phone":18,"phoneExt":18,"email":18},"Xinglei Shen",{"facility":249,"status":41,"city":250,"state":251,"zip":252,"country":45,"countryCode":46,"cosmosGeoPoint":253,"geoPoint":257,"contacts":258},"Mary Bird Perkins Cancer Center","Baton Rouge","Louisiana","70809",{"type":48,"coordinates":254},[255,256],-91.18747,30.44332,{"lat":256,"lon":255},[259,263],{"name":260,"role":33,"phone":261,"phoneExt":18,"email":262},"Courtney Hill","225-215-1353","chill@marybird.com",{"name":264,"role":60,"phone":18,"phoneExt":18,"email":18},"Victor Lin",{"facility":266,"status":41,"city":267,"state":251,"zip":268,"country":45,"countryCode":46,"cosmosGeoPoint":269,"geoPoint":273,"contacts":274},"East Jefferson Hospital","Metairie","70006",{"type":48,"coordinates":270},[271,272],-90.15285,29.98409,{"lat":272,"lon":271},[275,278],{"name":276,"role":33,"phone":18,"phoneExt":18,"email":277},"Alexandra Lieberman","alexandra.lieberman@lcmchealth.org",{"name":279,"role":60,"phone":18,"phoneExt":18,"email":18},"Alton Oliver Sartor",{"facility":281,"status":41,"city":282,"state":283,"zip":284,"country":45,"countryCode":46,"cosmosGeoPoint":285,"geoPoint":289,"contacts":290},"University of Maryland Medical Ctr","Baltimore","Maryland","21201",{"type":48,"coordinates":286},[287,288],-76.61219,39.29038,{"lat":288,"lon":287},[291,295],{"name":292,"role":33,"phone":293,"phoneExt":18,"email":294},"Dawn Barth","410-328-8667","Dawn.Barth@umm.edu",{"name":296,"role":60,"phone":18,"phoneExt":18,"email":18},"Arif Hussain",{"facility":298,"status":41,"city":282,"state":283,"zip":299,"country":45,"countryCode":46,"cosmosGeoPoint":300,"geoPoint":302,"contacts":303},"Johns Hopkins Kimmel Com Cancer Ctr","21231",{"type":48,"coordinates":301},[287,288],{"lat":288,"lon":287},[304,307],{"name":305,"role":33,"phone":18,"phoneExt":18,"email":306},"Dana Kaplan","dkaplin1@jhmi.edu",{"name":308,"role":60,"phone":18,"phoneExt":18,"email":18},"Ana Kiess",{"facility":310,"status":41,"city":311,"state":312,"zip":313,"country":45,"countryCode":46,"cosmosGeoPoint":314,"geoPoint":318,"contacts":319},"Dana Farber Cancer Institute","Boston","Massachusetts","02115",{"type":48,"coordinates":315},[316,317],-71.05977,42.35843,{"lat":317,"lon":316},[320,323],{"name":321,"role":33,"phone":18,"phoneExt":18,"email":322},"Sinead Christensen","smchristensen@bwh.harvard.edu",{"name":324,"role":60,"phone":18,"phoneExt":18,"email":18},"Mai Anh Huynh",{"facility":326,"status":41,"city":311,"state":312,"zip":327,"country":45,"countryCode":46,"cosmosGeoPoint":328,"geoPoint":330,"contacts":331},"Beth Israel Deaconess Med Ctr","02215",{"type":48,"coordinates":329},[316,317],{"lat":317,"lon":316},[332,335],{"name":333,"role":33,"phone":18,"phoneExt":18,"email":334},"Stephen Duggan","sduggan@bidmc.harvard.edu",{"name":336,"role":60,"phone":18,"phoneExt":18,"email":18},"David J Einstein",{"facility":338,"status":41,"city":339,"state":340,"zip":341,"country":45,"countryCode":46,"cosmosGeoPoint":342,"geoPoint":346,"contacts":347},"BAMF Health","Grand Rapids","Michigan","49503",{"type":48,"coordinates":343},[344,345],-85.66809,42.96336,{"lat":345,"lon":344},[348,351],{"name":349,"role":33,"phone":18,"phoneExt":18,"email":350},"Kamara Kam Bailey","kam.bailey@bamfhealth.com",{"name":352,"role":60,"phone":18,"phoneExt":18,"email":18},"Brandon Mancini",{"facility":354,"status":355,"city":356,"state":340,"zip":357,"country":45,"countryCode":46,"cosmosGeoPoint":358,"geoPoint":362,"contacts":18},"Profound Research LLC","WITHDRAWN","Royal Oak","48073",{"type":48,"coordinates":359},[360,361],-83.14465,42.48948,{"lat":361,"lon":360},{"facility":364,"status":41,"city":356,"state":340,"zip":357,"country":45,"countryCode":46,"cosmosGeoPoint":365,"geoPoint":367,"contacts":368},"William Beaumont Hospital",{"type":48,"coordinates":366},[360,361],{"lat":361,"lon":360},[369,373],{"name":370,"role":33,"phone":371,"phoneExt":18,"email":372},"Jennifer Murray","248-551-6485","jennifer.murray@beaumont.org",{"name":374,"role":60,"phone":18,"phoneExt":18,"email":18},"Andrew Thompson",{"facility":376,"status":41,"city":377,"state":378,"zip":379,"country":45,"countryCode":46,"cosmosGeoPoint":380,"geoPoint":384,"contacts":385},"Mayo Clinic Rochester","Rochester","Minnesota","55905",{"type":48,"coordinates":381},[382,383],-92.4699,44.02163,{"lat":383,"lon":382},[386,390],{"name":387,"role":33,"phone":388,"phoneExt":18,"email":389},"Takeru Walleser","507-538-2155","Walleser.Takeru@mayo.edu",{"name":391,"role":60,"phone":18,"phoneExt":18,"email":18},"Ryan Phillips",{"facility":393,"status":41,"city":394,"state":395,"zip":396,"country":45,"countryCode":46,"cosmosGeoPoint":397,"geoPoint":401,"contacts":402},"St Louis University","St Louis","Missouri","63104",{"type":48,"coordinates":398},[399,400],-90.19789,38.62727,{"lat":400,"lon":399},[403,406],{"name":404,"role":33,"phone":18,"phoneExt":18,"email":405},"Sabrina Abdullaeva","sabrina.abdullaeva@health.slu.edu",{"name":407,"role":60,"phone":18,"phoneExt":18,"email":18},"Medhat Osman",{"facility":409,"status":41,"city":394,"state":395,"zip":410,"country":45,"countryCode":46,"cosmosGeoPoint":411,"geoPoint":413,"contacts":414},"VA St Louis Health Care System","63106",{"type":48,"coordinates":412},[399,400],{"lat":400,"lon":399},[415,419],{"name":416,"role":33,"phone":417,"phoneExt":18,"email":418},"Janine Kampelman","314-652-4100","janine.kampelman@va.gov",{"name":407,"role":60,"phone":18,"phoneExt":18,"email":18},{"facility":421,"status":41,"city":394,"state":395,"zip":422,"country":45,"countryCode":46,"cosmosGeoPoint":423,"geoPoint":425,"contacts":426},"Wash U School of Medicine","63110",{"type":48,"coordinates":424},[399,400],{"lat":400,"lon":399},[427,430],{"name":428,"role":33,"phone":18,"phoneExt":18,"email":429},"Collin Welch","c.welch@wustl.edu",{"name":431,"role":60,"phone":18,"phoneExt":18,"email":18},"Hiram Gay",{"facility":433,"status":41,"city":434,"state":435,"zip":436,"country":45,"countryCode":46,"cosmosGeoPoint":437,"geoPoint":441,"contacts":442},"The Urology Center PC DBA UroHealth Partners","Omaha","Nebraska","68114",{"type":48,"coordinates":438},[439,440],-95.94043,41.25626,{"lat":440,"lon":439},[443,446],{"name":444,"role":33,"phone":18,"phoneExt":18,"email":445},"Amy Nelson","anelson@urohealthpartners.com",{"name":447,"role":60,"phone":18,"phoneExt":18,"email":18},"Andrew Trainer",{"facility":449,"status":41,"city":450,"state":450,"zip":451,"country":45,"countryCode":46,"cosmosGeoPoint":452,"geoPoint":456,"contacts":457},"Memorial Sloan Kettering Cancer Ctr","New York","10065",{"type":48,"coordinates":453},[454,455],-74.00597,40.71427,{"lat":455,"lon":454},[458,462],{"name":459,"role":33,"phone":460,"phoneExt":18,"email":461},"Viktoria Matessi","212-639-3854","matessiv@mskcc.org",{"name":463,"role":60,"phone":18,"phoneExt":18,"email":18},"Daniel Gorovets",{"facility":465,"status":41,"city":466,"state":450,"zip":467,"country":45,"countryCode":46,"cosmosGeoPoint":468,"geoPoint":472,"contacts":473},"Associated Med Professionals of NY","Syracuse","13210",{"type":48,"coordinates":469},[470,471],-76.14742,43.04812,{"lat":471,"lon":470},[474,477],{"name":475,"role":33,"phone":18,"phoneExt":18,"email":476},"Alex Bart","alex.bart@ampofny.com",{"name":478,"role":60,"phone":18,"phoneExt":18,"email":18},"Steven Finkelstein",{"facility":480,"status":41,"city":481,"state":450,"zip":482,"country":45,"countryCode":46,"cosmosGeoPoint":483,"geoPoint":487,"contacts":488},"Montefiore Hospital","The Bronx","10467 2490",{"type":48,"coordinates":484},[485,486],-73.86641,40.84985,{"lat":486,"lon":485},[489,493],{"name":490,"role":33,"phone":491,"phoneExt":18,"email":492},"Darciann O Sullivan","267-455-2717","dosulli@montefiore.org",{"name":494,"role":60,"phone":18,"phoneExt":18,"email":18},"Benjamin A Gartrell",{"facility":496,"status":41,"city":497,"state":498,"zip":499,"country":45,"countryCode":46,"cosmosGeoPoint":500,"geoPoint":504,"contacts":505},"East Carolina University","Greenville","North Carolina","27858",{"type":48,"coordinates":501},[502,503],-77.36635,35.61266,{"lat":503,"lon":502},[506,510],{"name":507,"role":33,"phone":508,"phoneExt":18,"email":509},"Kayleigh Nunley","252-744-0456","nunleyk16@ecu.edu",{"name":511,"role":60,"phone":18,"phoneExt":18,"email":18},"Andrew Ju",{"facility":513,"status":41,"city":514,"state":515,"zip":516,"country":45,"countryCode":46,"cosmosGeoPoint":517,"geoPoint":521,"contacts":522},"Dayton Physicians","Kettering","Ohio","45409",{"type":48,"coordinates":518},[519,520],-84.16883,39.6895,{"lat":520,"lon":519},[523,527],{"name":524,"role":33,"phone":525,"phoneExt":18,"email":526},"Lynette Tipton","937-771-2287","Lynette.Tipton@StatResearch.com",{"name":528,"role":60,"phone":18,"phoneExt":18,"email":18},"Trevor Bluemel",{"facility":530,"status":41,"city":531,"state":532,"zip":533,"country":45,"countryCode":46,"cosmosGeoPoint":534,"geoPoint":538,"contacts":539},"Oregon Urology Institute","Springfield","Oregon","97477",{"type":48,"coordinates":535},[536,537],-123.02203,44.04624,{"lat":537,"lon":536},[540,544],{"name":541,"role":33,"phone":542,"phoneExt":18,"email":543},"Victoria Evans","541-284-5508","vevans@oregonurology.com",{"name":545,"role":60,"phone":18,"phoneExt":18,"email":18},"Bryan Mehlhaff",{"facility":547,"status":41,"city":548,"state":549,"zip":550,"country":45,"countryCode":46,"cosmosGeoPoint":551,"geoPoint":555,"contacts":556},"Coastal Cancer Center","Conway","South Carolina","29526",{"type":48,"coordinates":552},[553,554],-79.04781,33.836,{"lat":554,"lon":553},[557],{"name":558,"role":60,"phone":18,"phoneExt":18,"email":18},"Neal D Shore",{"facility":560,"status":41,"city":561,"state":549,"zip":562,"country":45,"countryCode":46,"cosmosGeoPoint":563,"geoPoint":567,"contacts":568},"Carolina Urologic Research Center","Myrtle Beach","29572",{"type":48,"coordinates":564},[565,566],-78.88669,33.68906,{"lat":566,"lon":565},[569,573],{"name":570,"role":33,"phone":571,"phoneExt":18,"email":572},"Rebecca Floyd","843-839-1679","rebecca.floyd@startresearch.com",{"name":558,"role":60,"phone":18,"phoneExt":18,"email":18},{"facility":575,"status":41,"city":561,"state":549,"zip":576,"country":45,"countryCode":46,"cosmosGeoPoint":577,"geoPoint":579,"contacts":580},"Carolina Regional Cancer Center","29577",{"type":48,"coordinates":578},[565,566],{"lat":566,"lon":565},[581],{"name":558,"role":60,"phone":18,"phoneExt":18,"email":18},{"facility":583,"status":41,"city":584,"state":585,"zip":586,"country":45,"countryCode":46,"cosmosGeoPoint":587,"geoPoint":591,"contacts":592},"Vanderbilt University Medical Center","Nashville","Tennessee","37232",{"type":48,"coordinates":588},[589,590],-86.78444,36.16589,{"lat":590,"lon":589},[593,596],{"name":594,"role":33,"phone":18,"phoneExt":18,"email":595},"Laura Diedrich","laura.diedrich@vumc.org",{"name":597,"role":60,"phone":18,"phoneExt":18,"email":18},"Kerry Schaffer",{"facility":599,"status":41,"city":600,"state":601,"zip":602,"country":45,"countryCode":46,"cosmosGeoPoint":603,"geoPoint":607,"contacts":608},"Univ of Texas Southwest Med Center","Dallas","Texas","75390-9034",{"type":48,"coordinates":604},[605,606],-96.80667,32.78306,{"lat":606,"lon":605},[609,613],{"name":610,"role":33,"phone":611,"phoneExt":18,"email":612},"Amy Rowell","214-645-5905","Amy.Rowell@UTSouthwestern.edu",{"name":614,"role":60,"phone":18,"phoneExt":18,"email":18},"Kevin Courtney",{"facility":616,"status":41,"city":617,"state":601,"zip":618,"country":45,"countryCode":46,"cosmosGeoPoint":619,"geoPoint":623,"contacts":624},"Rio Grande Urology","El Paso","79912",{"type":48,"coordinates":620},[621,622],-106.48693,31.75872,{"lat":622,"lon":621},[625,628],{"name":626,"role":33,"phone":18,"phoneExt":18,"email":627},"Paola Delgado","pdelgado@riograndeurology.com",{"name":629,"role":60,"phone":18,"phoneExt":18,"email":18},"Jameson T Mendel",{"facility":631,"status":41,"city":632,"state":633,"zip":634,"country":45,"countryCode":46,"cosmosGeoPoint":635,"geoPoint":639,"contacts":640},"Virginia Oncology Associates","Norfolk","Virginia","23502",{"type":48,"coordinates":636},[637,638],-76.28522,36.84681,{"lat":638,"lon":637},[641,645],{"name":642,"role":33,"phone":643,"phoneExt":18,"email":644},"Amber Ingram","757-466-8683","amber.ingram@usoncology.com",{"name":646,"role":60,"phone":18,"phoneExt":18,"email":18},"Mark Fleming",{"facility":648,"status":41,"city":649,"state":633,"zip":650,"country":45,"countryCode":46,"cosmosGeoPoint":651,"geoPoint":655,"contacts":656},"Blue Ridge Cancer Center","Wytheville","24382",{"type":48,"coordinates":652},[653,654],-81.08481,36.94845,{"lat":654,"lon":653},[657,660],{"name":658,"role":33,"phone":18,"phoneExt":18,"email":659},"Gayatri Chembula","gayatri.chembula@usoncology.com",{"name":661,"role":60,"phone":18,"phoneExt":18,"email":18},"David Buck",{"facility":663,"status":41,"city":664,"state":665,"zip":666,"country":667,"countryCode":668,"cosmosGeoPoint":18,"geoPoint":18,"contacts":18},"Novartis Investigative Site","CABA","Buenos Aires","C1426ANZ","Argentina","AR",{"facility":663,"status":41,"city":664,"state":18,"zip":670,"country":667,"countryCode":668,"cosmosGeoPoint":18,"geoPoint":18,"contacts":18},"C1181ACH",{"facility":663,"status":41,"city":672,"state":18,"zip":673,"country":667,"countryCode":668,"cosmosGeoPoint":18,"geoPoint":18,"contacts":18},"Caba","C1431FWO",{"facility":663,"status":41,"city":675,"state":676,"zip":677,"country":678,"countryCode":679,"cosmosGeoPoint":680,"geoPoint":684,"contacts":18},"Darlinghurst","New South Wales","2010","Australia","AU",{"type":48,"coordinates":681},[682,683],151.21925,-33.87939,{"lat":683,"lon":682},{"facility":663,"status":41,"city":686,"state":687,"zip":688,"country":678,"countryCode":679,"cosmosGeoPoint":689,"geoPoint":693,"contacts":18},"Herston","Queensland","4029",{"type":48,"coordinates":690},[691,692],153.01852,-27.44453,{"lat":692,"lon":691},{"facility":663,"status":41,"city":695,"state":696,"zip":697,"country":678,"countryCode":679,"cosmosGeoPoint":698,"geoPoint":702,"contacts":18},"Adelaide","South Australia","5000",{"type":48,"coordinates":699},[700,701],138.59863,-34.92866,{"lat":701,"lon":700},{"facility":663,"status":41,"city":704,"state":705,"zip":706,"country":678,"countryCode":679,"cosmosGeoPoint":707,"geoPoint":711,"contacts":18},"Malvern","Victoria","3144",{"type":48,"coordinates":708},[709,710],145.02811,-37.86259,{"lat":710,"lon":709},{"facility":663,"status":41,"city":713,"state":18,"zip":714,"country":715,"countryCode":716,"cosmosGeoPoint":717,"geoPoint":721,"contacts":18},"Linz","4020","Austria","AT",{"type":48,"coordinates":718},[719,720],14.28611,48.30639,{"lat":720,"lon":719},{"facility":663,"status":41,"city":723,"state":18,"zip":724,"country":715,"countryCode":716,"cosmosGeoPoint":725,"geoPoint":729,"contacts":18},"Vienna","1090",{"type":48,"coordinates":726},[727,728],16.37208,48.20849,{"lat":728,"lon":727},{"facility":663,"status":41,"city":731,"state":18,"zip":732,"country":733,"countryCode":734,"cosmosGeoPoint":735,"geoPoint":739,"contacts":18},"Aalst","9300","Belgium","BE",{"type":48,"coordinates":736},[737,738],4.0355,50.93604,{"lat":738,"lon":737},{"facility":663,"status":41,"city":741,"state":18,"zip":742,"country":733,"countryCode":734,"cosmosGeoPoint":743,"geoPoint":747,"contacts":18},"Ghent","9000",{"type":48,"coordinates":744},[745,746],3.71667,51.05,{"lat":746,"lon":745},{"facility":663,"status":41,"city":749,"state":18,"zip":750,"country":733,"countryCode":734,"cosmosGeoPoint":751,"geoPoint":755,"contacts":18},"Wilrijk","2610",{"type":48,"coordinates":752},[753,754],4.39513,51.16734,{"lat":754,"lon":753},{"facility":663,"status":41,"city":757,"state":757,"zip":758,"country":759,"countryCode":760,"cosmosGeoPoint":761,"geoPoint":765,"contacts":18},"São Paulo","01246 000","Brazil","BR",{"type":48,"coordinates":762},[763,764],-46.63611,-23.5475,{"lat":764,"lon":763},{"facility":663,"status":41,"city":767,"state":768,"zip":769,"country":770,"countryCode":771,"cosmosGeoPoint":772,"geoPoint":776,"contacts":18},"Calgary","Alberta","T2N 5G2","Canada","CA",{"type":48,"coordinates":773},[774,775],-114.08529,51.05011,{"lat":775,"lon":774},{"facility":663,"status":41,"city":778,"state":779,"zip":780,"country":770,"countryCode":771,"cosmosGeoPoint":781,"geoPoint":785,"contacts":18},"Halifax","Nova Scotia","B3H 2Y9",{"type":48,"coordinates":782},[783,784],-63.57688,44.64269,{"lat":784,"lon":783},{"facility":663,"status":41,"city":787,"state":788,"zip":789,"country":770,"countryCode":771,"cosmosGeoPoint":790,"geoPoint":794,"contacts":18},"London","Ontario","N6A 4G5",{"type":48,"coordinates":791},[792,793],-81.23304,42.98339,{"lat":793,"lon":792},{"facility":663,"status":41,"city":796,"state":788,"zip":797,"country":770,"countryCode":771,"cosmosGeoPoint":798,"geoPoint":802,"contacts":18},"Ottawa","K1H 8L6",{"type":48,"coordinates":799},[800,801],-75.69812,45.41117,{"lat":801,"lon":800},{"facility":663,"status":41,"city":804,"state":788,"zip":805,"country":770,"countryCode":771,"cosmosGeoPoint":806,"geoPoint":810,"contacts":18},"Toronto","M5G 2M9",{"type":48,"coordinates":807},[808,809],-79.39864,43.70643,{"lat":809,"lon":808},{"facility":663,"status":41,"city":812,"state":813,"zip":814,"country":770,"countryCode":771,"cosmosGeoPoint":815,"geoPoint":819,"contacts":18},"Montreal","Quebec","H2X 1R9",{"type":48,"coordinates":816},[817,818],-73.58781,45.50884,{"lat":818,"lon":817},{"facility":663,"status":41,"city":812,"state":813,"zip":821,"country":770,"countryCode":771,"cosmosGeoPoint":822,"geoPoint":824,"contacts":18},"H3T 1E2",{"type":48,"coordinates":823},[817,818],{"lat":818,"lon":817},{"facility":663,"status":41,"city":826,"state":813,"zip":827,"country":770,"countryCode":771,"cosmosGeoPoint":828,"geoPoint":832,"contacts":18},"Québec","G1J 1Z4",{"type":48,"coordinates":829},[830,831],-71.21454,46.81228,{"lat":831,"lon":830},{"facility":663,"status":41,"city":834,"state":18,"zip":835,"country":836,"countryCode":837,"cosmosGeoPoint":838,"geoPoint":842,"contacts":18},"Beijing","100036","China","CN",{"type":48,"coordinates":839},[840,841],116.39723,39.9075,{"lat":841,"lon":840},{"facility":663,"status":41,"city":844,"state":18,"zip":845,"country":836,"countryCode":837,"cosmosGeoPoint":846,"geoPoint":850,"contacts":18},"Guangzhou","510060",{"type":48,"coordinates":847},[848,849],113.25,23.11667,{"lat":849,"lon":848},{"facility":663,"status":41,"city":852,"state":18,"zip":853,"country":836,"countryCode":837,"cosmosGeoPoint":854,"geoPoint":858,"contacts":18},"Shanghai","200127",{"type":48,"coordinates":855},[856,857],121.45806,31.22222,{"lat":857,"lon":856},{"facility":663,"status":41,"city":860,"state":861,"zip":862,"country":863,"countryCode":864,"cosmosGeoPoint":18,"geoPoint":18,"contacts":18},"Bogota","Cundinamarca","110111","Colombia","CO",{"facility":663,"status":41,"city":866,"state":18,"zip":867,"country":863,"countryCode":864,"cosmosGeoPoint":868,"geoPoint":872,"contacts":18},"Bogotá","110131",{"type":48,"coordinates":869},[870,871],-74.08175,4.60971,{"lat":871,"lon":870},{"facility":663,"status":41,"city":874,"state":875,"zip":876,"country":877,"countryCode":18,"cosmosGeoPoint":878,"geoPoint":882,"contacts":18},"Ostrava","Poruba","708 52","Czechia",{"type":48,"coordinates":879},[880,881],18.28204,49.83465,{"lat":881,"lon":880},{"facility":663,"status":41,"city":884,"state":18,"zip":885,"country":877,"countryCode":18,"cosmosGeoPoint":886,"geoPoint":890,"contacts":18},"Olomouc","779 00",{"type":48,"coordinates":887},[888,889],17.25175,49.59552,{"lat":889,"lon":888},{"facility":663,"status":41,"city":892,"state":18,"zip":893,"country":877,"countryCode":18,"cosmosGeoPoint":894,"geoPoint":898,"contacts":18},"Prague","150 06",{"type":48,"coordinates":895},[896,897],14.42076,50.08804,{"lat":897,"lon":896},{"facility":663,"status":41,"city":900,"state":901,"zip":902,"country":903,"countryCode":904,"cosmosGeoPoint":905,"geoPoint":909,"contacts":18},"Saint-Cloud","Hauts De Seine","92210","France","FR",{"type":48,"coordinates":906},[907,908],2.20289,48.84598,{"lat":908,"lon":907},{"facility":663,"status":41,"city":911,"state":18,"zip":912,"country":903,"countryCode":904,"cosmosGeoPoint":913,"geoPoint":917,"contacts":18},"Angers","49055",{"type":48,"coordinates":914},[915,916],-0.55202,47.47156,{"lat":916,"lon":915},{"facility":663,"status":41,"city":919,"state":18,"zip":920,"country":903,"countryCode":904,"cosmosGeoPoint":921,"geoPoint":925,"contacts":18},"Bordeaux","33076",{"type":48,"coordinates":922},[923,924],-0.58046,44.84124,{"lat":924,"lon":923},{"facility":663,"status":41,"city":927,"state":18,"zip":928,"country":903,"countryCode":904,"cosmosGeoPoint":929,"geoPoint":933,"contacts":18},"Bron","69677",{"type":48,"coordinates":930},[931,932],4.91303,45.73865,{"lat":932,"lon":931},{"facility":663,"status":41,"city":935,"state":18,"zip":936,"country":903,"countryCode":904,"cosmosGeoPoint":937,"geoPoint":941,"contacts":18},"Clermont-Ferrand","63011",{"type":48,"coordinates":938},[939,940],3.08682,45.77969,{"lat":940,"lon":939},{"facility":663,"status":41,"city":943,"state":18,"zip":944,"country":903,"countryCode":904,"cosmosGeoPoint":945,"geoPoint":949,"contacts":18},"Rouen","76038",{"type":48,"coordinates":946},[947,948],1.09932,49.44313,{"lat":948,"lon":947},{"facility":663,"status":41,"city":951,"state":18,"zip":952,"country":903,"countryCode":904,"cosmosGeoPoint":953,"geoPoint":957,"contacts":18},"Saint-Herblain","44805",{"type":48,"coordinates":954},[955,956],-1.651,47.21154,{"lat":956,"lon":955},{"facility":663,"status":41,"city":959,"state":960,"zip":961,"country":962,"countryCode":963,"cosmosGeoPoint":964,"geoPoint":968,"contacts":18},"Munich","Bavaria","81377","Germany","DE",{"type":48,"coordinates":965},[966,967],11.57549,48.13743,{"lat":967,"lon":966},{"facility":663,"status":41,"city":970,"state":971,"zip":972,"country":962,"countryCode":963,"cosmosGeoPoint":973,"geoPoint":977,"contacts":18},"Cologne","North Rhine-Westphalia","50937",{"type":48,"coordinates":974},[975,976],6.95,50.93333,{"lat":976,"lon":975},{"facility":663,"status":41,"city":979,"state":18,"zip":980,"country":962,"countryCode":963,"cosmosGeoPoint":981,"geoPoint":985,"contacts":18},"Aachen","52074",{"type":48,"coordinates":982},[983,984],6.08342,50.77664,{"lat":984,"lon":983},{"facility":663,"status":41,"city":987,"state":18,"zip":988,"country":962,"countryCode":963,"cosmosGeoPoint":989,"geoPoint":993,"contacts":18},"Augsburg","86179",{"type":48,"coordinates":990},[991,992],10.89851,48.37154,{"lat":992,"lon":991},{"facility":663,"status":41,"city":995,"state":18,"zip":996,"country":962,"countryCode":963,"cosmosGeoPoint":997,"geoPoint":1001,"contacts":18},"Berlin","10249",{"type":48,"coordinates":998},[999,1000],13.41053,52.52437,{"lat":1000,"lon":999},{"facility":663,"status":41,"city":1003,"state":18,"zip":1004,"country":962,"countryCode":963,"cosmosGeoPoint":1005,"geoPoint":1009,"contacts":18},"Essen","45147",{"type":48,"coordinates":1006},[1007,1008],7.01228,51.45657,{"lat":1008,"lon":1007},{"facility":663,"status":41,"city":1011,"state":18,"zip":1012,"country":962,"countryCode":963,"cosmosGeoPoint":1013,"geoPoint":1017,"contacts":18},"Münster","48149",{"type":48,"coordinates":1014},[1015,1016],7.62571,51.96236,{"lat":1016,"lon":1015},{"facility":663,"status":41,"city":1019,"state":18,"zip":1020,"country":962,"countryCode":963,"cosmosGeoPoint":1021,"geoPoint":1025,"contacts":18},"Rostock","18057",{"type":48,"coordinates":1022},[1023,1024],12.14049,54.0887,{"lat":1024,"lon":1023},{"facility":663,"status":41,"city":1027,"state":18,"zip":1028,"country":1029,"countryCode":1030,"cosmosGeoPoint":1031,"geoPoint":1035,"contacts":18},"Athens","106 76","Greece","GR",{"type":48,"coordinates":1032},[1033,1034],23.72784,37.98376,{"lat":1034,"lon":1033},{"facility":663,"status":41,"city":1027,"state":18,"zip":1037,"country":1029,"countryCode":1030,"cosmosGeoPoint":1038,"geoPoint":1040,"contacts":18},"11528",{"type":48,"coordinates":1039},[1033,1034],{"lat":1034,"lon":1033},{"facility":663,"status":41,"city":1042,"state":18,"zip":1043,"country":1029,"countryCode":1030,"cosmosGeoPoint":1044,"geoPoint":1048,"contacts":18},"Thessaloniki","540 07",{"type":48,"coordinates":1045},[1046,1047],22.93493,40.64072,{"lat":1047,"lon":1046},{"facility":663,"status":41,"city":1050,"state":1051,"zip":1052,"country":1053,"countryCode":1054,"cosmosGeoPoint":1055,"geoPoint":1059,"contacts":18},"Debrecen","Hajdu Bihar Megye","4032","Hungary","HU",{"type":48,"coordinates":1056},[1057,1058],21.62444,47.53167,{"lat":1058,"lon":1057},{"facility":663,"status":41,"city":1061,"state":18,"zip":1062,"country":1053,"countryCode":1054,"cosmosGeoPoint":1063,"geoPoint":1067,"contacts":18},"Budapest","H 1122",{"type":48,"coordinates":1064},[1065,1066],19.04045,47.49835,{"lat":1066,"lon":1065},{"facility":663,"status":41,"city":1061,"state":18,"zip":1069,"country":1053,"countryCode":1054,"cosmosGeoPoint":1070,"geoPoint":1072,"contacts":18},"H-1083",{"type":48,"coordinates":1071},[1065,1066],{"lat":1066,"lon":1065},{"facility":663,"status":41,"city":1074,"state":18,"zip":1075,"country":1076,"countryCode":1077,"cosmosGeoPoint":1078,"geoPoint":1082,"contacts":18},"Beersheba","8457108","Israel","IL",{"type":48,"coordinates":1079},[1080,1081],34.7913,31.25181,{"lat":1081,"lon":1080},{"facility":663,"status":41,"city":1084,"state":18,"zip":1085,"country":1076,"countryCode":1077,"cosmosGeoPoint":1086,"geoPoint":1090,"contacts":18},"Haifa","3109601",{"type":48,"coordinates":1087},[1088,1089],34.99928,32.81303,{"lat":1089,"lon":1088},{"facility":663,"status":41,"city":1092,"state":18,"zip":1093,"country":1076,"countryCode":1077,"cosmosGeoPoint":1094,"geoPoint":1098,"contacts":18},"Jerusalem","9112001",{"type":48,"coordinates":1095},[1096,1097],35.21633,31.76904,{"lat":1097,"lon":1096},{"facility":663,"status":41,"city":1100,"state":18,"zip":1101,"country":1076,"countryCode":1077,"cosmosGeoPoint":1102,"geoPoint":1106,"contacts":18},"Petah Tikva","4941492",{"type":48,"coordinates":1103},[1104,1105],34.88747,32.08707,{"lat":1105,"lon":1104},{"facility":663,"status":41,"city":1108,"state":18,"zip":1109,"country":1076,"countryCode":1077,"cosmosGeoPoint":1110,"geoPoint":1114,"contacts":18},"Tel Aviv","6423906",{"type":48,"coordinates":1111},[1112,1113],34.78057,32.08088,{"lat":1113,"lon":1112},{"facility":663,"status":355,"city":1116,"state":1117,"zip":1118,"country":1119,"countryCode":1120,"cosmosGeoPoint":1121,"geoPoint":1125,"contacts":18},"Brescia","BS","25123","Italy","IT",{"type":48,"coordinates":1122},[1123,1124],10.21472,45.53558,{"lat":1124,"lon":1123},{"facility":663,"status":41,"city":1127,"state":1128,"zip":1129,"country":1119,"countryCode":1120,"cosmosGeoPoint":1130,"geoPoint":1134,"contacts":18},"Cona","FE","44124",{"type":48,"coordinates":1131},[1132,1133],11.7069,44.80583,{"lat":1133,"lon":1132},{"facility":663,"status":41,"city":1136,"state":1137,"zip":1138,"country":1119,"countryCode":1120,"cosmosGeoPoint":1139,"geoPoint":1143,"contacts":18},"Genova","GE","16132",{"type":48,"coordinates":1140},[1141,1142],11.87211,45.21604,{"lat":1142,"lon":1141},{"facility":663,"status":41,"city":1145,"state":1146,"zip":1147,"country":1119,"countryCode":1120,"cosmosGeoPoint":1148,"geoPoint":1152,"contacts":18},"Rozzano","MI","20089",{"type":48,"coordinates":1149},[1150,1151],9.1559,45.38193,{"lat":1151,"lon":1150},{"facility":663,"status":41,"city":1154,"state":1155,"zip":1156,"country":1119,"countryCode":1120,"cosmosGeoPoint":1157,"geoPoint":1161,"contacts":18},"Pisa","PI","56126",{"type":48,"coordinates":1158},[1159,1160],10.4036,43.70853,{"lat":1160,"lon":1159},{"facility":663,"status":41,"city":1163,"state":1164,"zip":1165,"country":1119,"countryCode":1120,"cosmosGeoPoint":1166,"geoPoint":1170,"contacts":18},"Roma","RM","00168",{"type":48,"coordinates":1167},[1168,1169],11.10642,44.99364,{"lat":1169,"lon":1168},{"facility":663,"status":41,"city":1172,"state":1173,"zip":1174,"country":1119,"countryCode":1120,"cosmosGeoPoint":1175,"geoPoint":1179,"contacts":18},"Negrar","VR","37024",{"type":48,"coordinates":1176},[1177,1178],10.93899,45.52918,{"lat":1178,"lon":1177},{"facility":663,"status":41,"city":1181,"state":18,"zip":1182,"country":1119,"countryCode":1120,"cosmosGeoPoint":1183,"geoPoint":1187,"contacts":18},"Milan","20141",{"type":48,"coordinates":1184},[1185,1186],12.59836,42.78235,{"lat":1186,"lon":1185},{"facility":663,"status":41,"city":1189,"state":1190,"zip":1191,"country":1192,"countryCode":1193,"cosmosGeoPoint":1194,"geoPoint":1198,"contacts":18},"Kashiwa","Chiba","277-8577","Japan","JP",{"type":48,"coordinates":1195},[1196,1197],139.97732,35.86224,{"lat":1197,"lon":1196},{"facility":663,"status":41,"city":1200,"state":1201,"zip":1202,"country":1192,"countryCode":1193,"cosmosGeoPoint":1203,"geoPoint":1207,"contacts":18},"Sapporo","Hokkaido","060-8648",{"type":48,"coordinates":1204},[1205,1206],141.35,43.06667,{"lat":1206,"lon":1205},{"facility":663,"status":41,"city":1209,"state":1210,"zip":1211,"country":1192,"countryCode":1193,"cosmosGeoPoint":1212,"geoPoint":1216,"contacts":18},"Kobe","Hyōgo","6500047",{"type":48,"coordinates":1213},[1214,1215],135.183,34.6913,{"lat":1215,"lon":1214},{"facility":663,"status":41,"city":1218,"state":1219,"zip":1220,"country":1192,"countryCode":1193,"cosmosGeoPoint":1221,"geoPoint":1225,"contacts":18},"Yokohama","Kanagawa","236-0004",{"type":48,"coordinates":1222},[1223,1224],139.65,35.43333,{"lat":1224,"lon":1223},{"facility":663,"status":41,"city":1227,"state":1228,"zip":1229,"country":1192,"countryCode":1193,"cosmosGeoPoint":18,"geoPoint":18,"contacts":18},"Chuo Ku","Tokyo","1040045",{"facility":663,"status":41,"city":1231,"state":18,"zip":1232,"country":1192,"countryCode":1193,"cosmosGeoPoint":1233,"geoPoint":1237,"contacts":18},"Fukuoka","811-0213",{"type":48,"coordinates":1234},[1235,1236],130.41667,33.6,{"lat":1236,"lon":1235},{"facility":663,"status":41,"city":1231,"state":18,"zip":1239,"country":1192,"countryCode":1193,"cosmosGeoPoint":1240,"geoPoint":1242,"contacts":18},"812-0033",{"type":48,"coordinates":1241},[1235,1236],{"lat":1236,"lon":1235},{"facility":663,"status":41,"city":1231,"state":18,"zip":1244,"country":1192,"countryCode":1193,"cosmosGeoPoint":1245,"geoPoint":1247,"contacts":18},"8128582",{"type":48,"coordinates":1246},[1235,1236],{"lat":1236,"lon":1235},{"facility":663,"status":41,"city":1249,"state":18,"zip":1250,"country":1192,"countryCode":1193,"cosmosGeoPoint":1251,"geoPoint":1255,"contacts":18},"Fukushima","9601295",{"type":48,"coordinates":1252},[1253,1254],140.46667,37.75,{"lat":1254,"lon":1253},{"facility":663,"status":41,"city":1257,"state":18,"zip":1258,"country":1192,"countryCode":1193,"cosmosGeoPoint":1259,"geoPoint":1263,"contacts":18},"Ishikawa","9208641",{"type":48,"coordinates":1260},[1261,1262],127.82139,26.42333,{"lat":1262,"lon":1261},{"facility":663,"status":41,"city":1265,"state":18,"zip":1266,"country":1192,"countryCode":1193,"cosmosGeoPoint":1267,"geoPoint":1271,"contacts":18},"Kyoto","6068507",{"type":48,"coordinates":1268},[1269,1270],135.75385,35.02107,{"lat":1270,"lon":1269},{"facility":663,"status":41,"city":1273,"state":1274,"zip":1275,"country":1276,"countryCode":1277,"cosmosGeoPoint":1278,"geoPoint":1282,"contacts":18},"Petaling Jaya","Selangor","46050","Malaysia","MY",{"type":48,"coordinates":1279},[1280,1281],101.60671,3.10726,{"lat":1281,"lon":1280},{"facility":663,"status":41,"city":1284,"state":18,"zip":1285,"country":1276,"countryCode":1277,"cosmosGeoPoint":1286,"geoPoint":1290,"contacts":18},"Kuala Lumpur","59100",{"type":48,"coordinates":1287},[1288,1289],101.68653,3.1412,{"lat":1289,"lon":1288},{"facility":663,"status":41,"city":1292,"state":1292,"zip":1293,"country":1294,"countryCode":1295,"cosmosGeoPoint":1296,"geoPoint":1300,"contacts":18},"Mexico City","14050","Mexico","MX",{"type":48,"coordinates":1297},[1298,1299],-99.12766,19.42847,{"lat":1299,"lon":1298},{"facility":663,"status":41,"city":1302,"state":18,"zip":1303,"country":1294,"countryCode":1295,"cosmosGeoPoint":18,"geoPoint":18,"contacts":18},"Huxquilucan","52763",{"facility":663,"status":41,"city":1305,"state":18,"zip":1306,"country":1307,"countryCode":1308,"cosmosGeoPoint":1309,"geoPoint":1313,"contacts":18},"Amsterdam","1066 CX","Netherlands","NL",{"type":48,"coordinates":1310},[1311,1312],4.88969,52.37403,{"lat":1312,"lon":1311},{"facility":1315,"status":41,"city":1316,"state":18,"zip":1317,"country":1318,"countryCode":1319,"cosmosGeoPoint":1320,"geoPoint":1324,"contacts":1325},"VA Caribbean Healthcare System","San Juan","00921","Puerto Rico","PR",{"type":48,"coordinates":1321},[1322,1323],-66.10572,18.46633,{"lat":1323,"lon":1322},[1326,1330],{"name":1327,"role":33,"phone":1328,"phoneExt":18,"email":1329},"Sara Fuentes-Medina","+17876417582#10393","Sara.Fuentes-Medina@va.gov",{"name":1331,"role":60,"phone":18,"phoneExt":18,"email":18},"Bartolo Santiago-Delgado",{"facility":663,"status":41,"city":1333,"state":18,"zip":1334,"country":1333,"countryCode":1335,"cosmosGeoPoint":1336,"geoPoint":1340,"contacts":18},"Singapore","119074","SG",{"type":48,"coordinates":1337},[1338,1339],103.85007,1.28967,{"lat":1339,"lon":1338},{"facility":663,"status":41,"city":1333,"state":18,"zip":1342,"country":1333,"countryCode":1335,"cosmosGeoPoint":1343,"geoPoint":1345,"contacts":18},"168583",{"type":48,"coordinates":1344},[1338,1339],{"lat":1339,"lon":1338},{"facility":663,"status":41,"city":1347,"state":18,"zip":1348,"country":1349,"countryCode":1350,"cosmosGeoPoint":1351,"geoPoint":1355,"contacts":18},"Bratislava","83310","Slovakia","SK",{"type":48,"coordinates":1352},[1353,1354],17.10674,48.14816,{"lat":1354,"lon":1353},{"facility":663,"status":41,"city":1357,"state":18,"zip":1358,"country":1349,"countryCode":1350,"cosmosGeoPoint":1359,"geoPoint":1363,"contacts":18},"Košice","041 91",{"type":48,"coordinates":1360},[1361,1362],21.25802,48.71441,{"lat":1362,"lon":1361},{"facility":663,"status":41,"city":1365,"state":18,"zip":1366,"country":1349,"countryCode":1350,"cosmosGeoPoint":1367,"geoPoint":1371,"contacts":18},"Nitra","949 01",{"type":48,"coordinates":1368},[1369,1370],18.08453,48.30763,{"lat":1370,"lon":1369},{"facility":663,"status":41,"city":1373,"state":18,"zip":1374,"country":1349,"countryCode":1350,"cosmosGeoPoint":1375,"geoPoint":1379,"contacts":18},"Trenčín","911 01",{"type":48,"coordinates":1376},[1377,1378],18.04436,48.89452,{"lat":1378,"lon":1377},{"facility":663,"status":41,"city":1381,"state":1382,"zip":1383,"country":1384,"countryCode":1385,"cosmosGeoPoint":1386,"geoPoint":1390,"contacts":18},"Granada","Andalusia","18014","Spain","ES",{"type":48,"coordinates":1387},[1388,1389],-3.60667,37.18817,{"lat":1389,"lon":1388},{"facility":663,"status":41,"city":1392,"state":1393,"zip":1394,"country":1384,"countryCode":1385,"cosmosGeoPoint":1395,"geoPoint":1399,"contacts":18},"Barcelona","Catalonia","08025",{"type":48,"coordinates":1396},[1397,1398],2.15899,41.38879,{"lat":1398,"lon":1397},{"facility":663,"status":41,"city":1401,"state":1402,"zip":1403,"country":1384,"countryCode":1385,"cosmosGeoPoint":1404,"geoPoint":1408,"contacts":18},"El Palmar","Murcia","30120",{"type":48,"coordinates":1405},[1406,1407],-1.16095,37.93939,{"lat":1407,"lon":1406},{"facility":663,"status":41,"city":1392,"state":18,"zip":1410,"country":1384,"countryCode":1385,"cosmosGeoPoint":1411,"geoPoint":1413,"contacts":18},"08036",{"type":48,"coordinates":1412},[1397,1398],{"lat":1398,"lon":1397},{"facility":663,"status":41,"city":1415,"state":18,"zip":1416,"country":1384,"countryCode":1385,"cosmosGeoPoint":1417,"geoPoint":1421,"contacts":18},"Madrid","28040",{"type":48,"coordinates":1418},[1419,1420],-3.70256,40.4165,{"lat":1420,"lon":1419},{"facility":663,"status":41,"city":1415,"state":18,"zip":1423,"country":1384,"countryCode":1385,"cosmosGeoPoint":1424,"geoPoint":1426,"contacts":18},"28041",{"type":48,"coordinates":1425},[1419,1420],{"lat":1420,"lon":1419},{"facility":663,"status":41,"city":1428,"state":18,"zip":1429,"country":1384,"countryCode":1385,"cosmosGeoPoint":1430,"geoPoint":1434,"contacts":18},"Seville","41013",{"type":48,"coordinates":1431},[1432,1433],-5.97317,37.38283,{"lat":1433,"lon":1432},{"facility":663,"status":41,"city":1436,"state":18,"zip":1437,"country":1384,"countryCode":1385,"cosmosGeoPoint":1438,"geoPoint":1442,"contacts":18},"Valencia","46010",{"type":48,"coordinates":1439},[1440,1441],-0.37966,39.47391,{"lat":1441,"lon":1440},{"facility":663,"status":41,"city":1444,"state":18,"zip":1445,"country":1446,"countryCode":1447,"cosmosGeoPoint":1448,"geoPoint":1452,"contacts":18},"Geneva","1211","Switzerland","CH",{"type":48,"coordinates":1449},[1450,1451],6.14569,46.20222,{"lat":1451,"lon":1450},{"facility":663,"status":41,"city":1454,"state":18,"zip":1455,"country":1446,"countryCode":1447,"cosmosGeoPoint":1456,"geoPoint":1460,"contacts":18},"Lucerne","6006",{"type":48,"coordinates":1457},[1458,1459],8.30635,47.05048,{"lat":1459,"lon":1458},{"facility":663,"status":41,"city":1462,"state":18,"zip":1463,"country":1446,"countryCode":1447,"cosmosGeoPoint":1464,"geoPoint":1468,"contacts":18},"Zurich","8063",{"type":48,"coordinates":1465},[1466,1467],8.55,47.36667,{"lat":1467,"lon":1466},{"facility":663,"status":41,"city":1470,"state":18,"zip":1471,"country":1472,"countryCode":1473,"cosmosGeoPoint":1474,"geoPoint":1478,"contacts":18},"Taipei","10002","Taiwan","TW",{"type":48,"coordinates":1475},[1476,1477],121.52639,25.05306,{"lat":1477,"lon":1476},{"facility":663,"status":41,"city":1470,"state":18,"zip":1480,"country":1472,"countryCode":1473,"cosmosGeoPoint":1481,"geoPoint":1483,"contacts":18},"103616",{"type":48,"coordinates":1482},[1476,1477],{"lat":1477,"lon":1476},{"facility":663,"status":41,"city":1470,"state":18,"zip":1485,"country":1472,"countryCode":1473,"cosmosGeoPoint":1486,"geoPoint":1488,"contacts":18},"11217",{"type":48,"coordinates":1487},[1476,1477],{"lat":1477,"lon":1476},{"facility":663,"status":41,"city":1490,"state":18,"zip":1491,"country":1472,"countryCode":1473,"cosmosGeoPoint":1492,"geoPoint":1496,"contacts":18},"Taoyuan","33305",{"type":48,"coordinates":1493},[1494,1495],121.29696,24.99368,{"lat":1495,"lon":1494},{"facility":663,"status":41,"city":1498,"state":1499,"zip":1500,"country":1501,"countryCode":1502,"cosmosGeoPoint":1503,"geoPoint":1507,"contacts":18},"Bristol","Avon","BS2 8ED","United Kingdom","UK",{"type":48,"coordinates":1504},[1505,1506],-2.59665,51.45523,{"lat":1506,"lon":1505},{"facility":663,"status":41,"city":1509,"state":1510,"zip":1511,"country":1501,"countryCode":1502,"cosmosGeoPoint":1512,"geoPoint":1516,"contacts":18},"Guildford","Surrey","GU2 7XX",{"type":48,"coordinates":1513},[1514,1515],-0.57427,51.23536,{"lat":1515,"lon":1514},{"facility":663,"status":41,"city":1518,"state":1510,"zip":1519,"country":1501,"countryCode":1502,"cosmosGeoPoint":1520,"geoPoint":1524,"contacts":18},"Sutton","SM2 5PT",{"type":48,"coordinates":1521},[1522,1523],-0.2,51.35,{"lat":1523,"lon":1522},{"facility":663,"status":41,"city":1526,"state":18,"zip":1527,"country":1501,"countryCode":1502,"cosmosGeoPoint":1528,"geoPoint":1532,"contacts":18},"Coventry","CV2 2DX",{"type":48,"coordinates":1529},[1530,1531],-1.51217,52.40656,{"lat":1531,"lon":1530},{"facility":663,"status":41,"city":787,"state":18,"zip":1534,"country":1501,"countryCode":1502,"cosmosGeoPoint":1535,"geoPoint":1539,"contacts":18},"NW3 2QG",{"type":48,"coordinates":1536},[1537,1538],-0.12574,51.50853,{"lat":1538,"lon":1537},{"type":1541,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100511436","phase-3-an-open-label-study-comparing-lutetium-177lu-vipivotide-tetraxetan-versus-observation-in-psma-positive-ompc-100511436",false,"NCT05939414","An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.","An International, Prospective, Open-label, Multi-center, Randomized Phase III Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) Versus Observation to Delay Castration or Disease Recurrence in Adult Male Patients With Prostate-specific Membrane Antigen (PSMA) Positive Oligometastatic Prostate Cancer (OMPC)","PSMA-DC","Key Inclusion criteria:\n\n1. Histologically confirmed prostate cancer prior to randomization\n2. Participants must have biochemically recurrent disease after definitive treatment to prostate by Radical Prostatectomy ((RP), (alone or with post-operative radiation to prostate bed\u002Fpelvic nodes)) or External beam Radiation Therapy (EBRT), (prostate alone or prostate with seminal vesicle and\u002For pelvic nodes) and\u002For brachytherapy prior to randomization. Biochemical recurrence (BCR) is defined as: nadir PSA + 2 ng\u002FmL post XRT (if participant received-radiation therapy to intact prostate) and PSA \\> 0.2 ng\u002FmL and rising post RP (with or without post-operation Radiation Therapy (RT))\n3. Participants must have OMPC with 1-5 PSMA -positive metastatic lesions on screening PSMA PET\u002FCT scan (with either gallium (68Ga) gozetotide or piflufolastat (18F)) as visually assessed by BIRC. For definition of PSMA PET positivity, please refer to Section 8.1 and the Imaging Manual. Metastatic lesions may include regional\u002Fpelvic lymph nodes (N1), distant lymph nodes (M1a), bone (M1b), lung and others visceral (M1c) except liver and brain classified using American Joint Committee on Cancer (AJCC) 8. When counting the number of oligometastatic lesions, each lesion is counted as distinct metastasis irrespective of its anatomical location (e.g., one pelvic and one extra-pelvic lymph node will be counted as two metastatic lesions)\n4. At least 1 PSMA-positive lesion must be a distant metastasis (M1) per AJCC8 classification at screening. For AJCC M staging, PSMA PET\u002FCT information should be used\n5. Participants must have a negative CI for M1 disease at screening.\n\n   Note:\n   * For a participant not to be eligible, CI positive M1 lesions should be unequivocal in CI scans, i.e., potentially not attributable to findings thought to represent something other than tumor (e.g., degenerative, or post-traumatic changes or Paget's disease in bone lesions). For CI assessments, bone lesions must be assessed by bone scan only and soft tissue lesions must be assessed by CT\u002FMRI scans only at screening.\n   * Prior knowledge of PSMA PET positivity should not influence the radiologist (reader) in determination of CI positivity. Two different readers will be involved, one reader for PSMA PET\u002FCT scan and one reader for CI: Reader will be blinded to PSMA PET scan results while reading CI scans. Reader should not modify their assessment of CI scans (e.g. changing a lesion previously identified as equivocal in CI to unequivocal) after reading the PSMA PET scan. Similarly, biopsy positivity should not influence the reader in the assessment of CI positivity. More details on the reading paradigm will be provided in the imaging charter\n   * MRI for radiation treatment planning may show M1 disease but this will not exclude the participant from the study if the lesion is deemed negative per baseline CT or bone scans\n   * Participants with pelvic disease (N1) seen in CI are allowed if the local spread is below common iliac bifurcation (per AJCC 8 definition of local disease)\n   * Distant lymph node disease (M1a) that is visible per CI and less than 10mm in the short axis is not exclusionary irrespective of PSMA PET positivity.\n   * If a previously surgically removed lesion was unequivocal for M1 by bone scan or CT, the participant is not eligible.\n6. All metastatic lesions detected at screening must be amenable to SBRT\n7. Non-castration testosterone level \\>100 ng\u002FdL at screening\n\nKey Exclusion criteria:\n\n1. Participants with de novo OMPC at screening\n2. Unmanageable concurrent bladder outflow obstruction or urinary incontinence at screening. Note: participants with bladder outflow obstruction or urinary incontinence, which is manageable and controlled with best available standard of care (incl. pads, drainage) are allowed\n3. Prior therapy with:\n\n   1. ADT (including bilateral orchiectomy) and ARPIs used for metastatic prostate cancer treatment\n\n      * Participants who received AR-directed therapy, whether ADT or an ARPI or both, as neoadjuvant or adjuvant therapy as a component of their primary therapy, are eligible provided that they discontinued therapy ≥12 months prior to randomization for ADT (i.e., 12 months after the last day of the last injection) or ≥3 months if ARPI was given as monotherapy. ARPI's as a term includes both contemporary androgen synthesis inhibitors (e.g., abiraterone, galeterone, and orteneronel), and receptor inhibitors (enzalutamide, apalutamide and darolutamide).\n      * Patients who biochemically relapsed after primary therapy may also have had treatment with AR directed therapy and participants who had SBRT with ADT are also eligible provided that the ARPI +\u002F- ADT or ADT alone was terminated\n\n        ≥12 months prior to randomization for ADT (i.e., 12 months after the last day of the last injection) or ≥3 months if ARPI was given as monotherapy.\n      * Participants who received first generation anti-androgens (bicalutamide, flutamide, nilutamide, cyproterone) for biochemical recurrence or adjuvant\u002Fneoadjuvant therapy are eligible provided that they discontinued therapy ≥3 months prior to randomization.\n      * Participants who have discontinued ADT due to disease progression are not eligible (i.e., Castration-Resistant Prostate Cancer (CRPC) participants)\n   2. Other hormonal therapy. e.g.,\n\n      •Use of estrogens, 5-α reductase inhibitors (finasteride, dutasteride), other steroidogenesis inhibitors (aminoglutethimide) if used in the context of prostate cancer treatment. Same medications are allowed if used for other indications: e.g., Benign Prostatic Hyperplasia (BPH), if stopped ≥3 months before randomization.\n   3. Radiopharmaceutical agents (e.g., Strontium-89, PSMA-targeted radioligand therapy)\n   4. Immunotherapy (e.g., sipuleucel-T)\n   5. Chemotherapy, except if administered in the adjuvant\u002Fneoadjuvant setting completed \\> 12 months before randomization\n   6. Any other investigational or systemic agents for metastatic disease\n4. Radiation therapy external beam radiation therapy (EBRT) and brachytherapy within 28 days before randomization\n5. Concurrent cytotoxic chemotherapy, immunotherapy, radioligand therapy, hormonal therapy (see ADT initiation guidance in Section 6.8.2), Poly Adenosine Diphosphate-Ribose Polymerase (PARP) inhibitor, biological therapy or investigational therapy\n6. Diagnosed at screening with other malignancies that are expected to alter life expectancy or may interfere with disease assessment. However, participants with a prior history of malignancy that has been adequately treated and who have been disease\u002Ftreatment free for more than 3 years are eligible, as are participants with adequately treated non-melanoma skin cancer and superficial bladder cancer.\n7. History or current diagnosis of ECG abnormalities indicating significant risk of safety for participants participating in the study such as:\n\n   * Concomitant clinically significant cardiac arrhythmias, e.g. sustained ventricular tachycardia, and clinically significant second or third degree Atrioventricular (AV) block without a pacemaker\n   * History of familial long QT syndrome or known family history of Torsades de Pointe\n8. Participants in immediate need of ADT as assessed by the investigator.\n\nOther protocol defined Inclusion\u002FExclusion may apply.","MALE","18 Years","100 Years",{"count":1554,"type":1555},450,"ESTIMATED","INTERVENTIONAL",[1558],"PHASE3","The purpose of this study is to evaluate the efficacy and safety of lutetium (177Lu) vipivotide tetraxetan (AAA617) in participants with oligometastatic prostate cancer (OMPC) progressing after definitive therapy to their primary tumor. The data generated from this study will provide evidence for the treatment of AAA617 in early-stage prostate cancer patients to control recurrent tumor from progressing to fatal metastatic disease while preserving quality of life by delaying treatment with androgen deprivation therapy (ADT).",[1561],"Oligometastatic Prostate Cancer (OMPC)",[1563,1561,1564,1565,1566,1567,1568,1569,1570,1571],"Lutetium (177Lu) vipivotide tetraxetan","Metastasis Free Survival (MFS)","gallium (68Ga) gozetotide","piflufolastat (18F)","prostate-specific membrane antigen (PSMA)","Delay Castration","Stereotactic Body Radiation Therapy (SBRT)","metastasis-directed therapy","Androgen Deprivation Therapy (ADT)-free survival.","2026-06-08",{"date":1574,"type":1575},"2026-06-10","ACTUAL",{"date":1577,"type":1575},"2024-03-12",{"date":1579,"type":1555},"2031-10-03",{"name":29,"class":6},147]