[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100487333":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":44,"responsibleParty":312,"collaborators":25,"id":314,"slug":315,"hasResults":316,"nctId":317,"briefTitle":318,"officialTitle":319,"acronym":320,"eligibilityCriteria":321,"healthyVolunteers":316,"sex":322,"minAge":323,"maxAge":25,"enrollmentInfo":324,"targetDuration":25,"studyType":327,"phases":328,"briefSummary":330,"conditions":331,"keywords":25,"overallStatus":47,"whyStopped":25,"lastUpdateSubmitDate":334,"lastUpdatePostDateStruct":335,"startDateStruct":338,"completionDateStruct":340,"leadSponsor":342,"locationsCount":343},{"fullName":5,"class":6},"University Hospital, Toulouse","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Aspirin","EXPERIMENTAL","Low-dose Aspirin: 150mg, daily, oral route, at bedtime, initiated between 9 and 14 weeks of gestation, until 35 (+6) weeks of gestation, or in the event of earlier delivery, until the onset of labor.",[13],"Drug: Aspirin",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","PLACEBO_COMPARATOR","Matching placebo administrated daily, oral route, at bedtime, initiated between 9 and 14 weeks of gestation, until 35 (+6) weeks of gestation, or in the event of earlier delivery, until the onset of labor.",[19],"Drug: Placebo",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Experimental drug administrated orally",[9],null,{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Placebo","Treatment for the control group",[15],[31],{"name":32,"affiliation":5,"role":33},"Christophe VAYSSIERE, MD","PRINCIPAL_INVESTIGATOR",[35,40],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"Paul GUERBY, MD","CONTACT","5 67 77 12 33","guerby.p@chu-toulouse.fr",{"name":41,"role":37,"phone":38,"phoneExt":42,"email":43},"Delphine DUCHANOIS, Midwife","+33","duchanois.d@chu-toulouse.fr",[45,62,75,88,101,114,127,140,150,163,176,189,202,215,226,236,249,262,275,288,301],{"facility":46,"status":47,"city":48,"state":25,"zip":25,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"CHU Angers","RECRUITING","Angers","France","FR",{"type":52,"coordinates":53},"Point",[54,55],-0.55202,47.47156,{"lat":55,"lon":54},[58,60],{"name":59,"role":37,"phone":25,"phoneExt":25,"email":25},"Pierre-Emmanuel BOUET, MD",{"name":61,"role":33,"phone":25,"phoneExt":25,"email":25},"Pierre-Emmanuel BOUET",{"facility":63,"status":47,"city":64,"state":25,"zip":25,"country":49,"countryCode":50,"cosmosGeoPoint":65,"geoPoint":69,"contacts":70},"CHU Bordeaux","Bordeaux",{"type":52,"coordinates":66},[67,68],-0.58046,44.84124,{"lat":68,"lon":67},[71,73],{"name":72,"role":37,"phone":25,"phoneExt":25,"email":25},"Loic Sentilhes, MD",{"name":74,"role":33,"phone":25,"phoneExt":25,"email":25},"Loic SENTILHES",{"facility":76,"status":47,"city":77,"state":25,"zip":25,"country":49,"countryCode":50,"cosmosGeoPoint":78,"geoPoint":82,"contacts":83},"CHU Clermont-Ferrand","Clermont-Ferrand",{"type":52,"coordinates":79},[80,81],3.08682,45.77969,{"lat":81,"lon":80},[84,86],{"name":85,"role":37,"phone":25,"phoneExt":25,"email":25},"Amélie DELABAERE, MD",{"name":87,"role":33,"phone":25,"phoneExt":25,"email":25},"Amélie DELABAERE",{"facility":89,"status":47,"city":90,"state":25,"zip":25,"country":49,"countryCode":50,"cosmosGeoPoint":91,"geoPoint":95,"contacts":96},"CHU Dijon-Bourgogne","Dijon",{"type":52,"coordinates":92},[93,94],5.01391,47.31344,{"lat":94,"lon":93},[97,99],{"name":98,"role":37,"phone":25,"phoneExt":25,"email":25},"Emmanuel Simon, MD",{"name":100,"role":33,"phone":25,"phoneExt":25,"email":25},"Emmanuel SIMON",{"facility":102,"status":47,"city":103,"state":25,"zip":25,"country":49,"countryCode":50,"cosmosGeoPoint":104,"geoPoint":108,"contacts":109},"CHU Lille","Lille",{"type":52,"coordinates":105},[106,107],3.05512,50.63391,{"lat":107,"lon":106},[110,112],{"name":111,"role":37,"phone":25,"phoneExt":25,"email":25},"Véronique Debarge, MD",{"name":113,"role":33,"phone":25,"phoneExt":25,"email":25},"Véronique DEBARGE",{"facility":115,"status":47,"city":116,"state":25,"zip":25,"country":49,"countryCode":50,"cosmosGeoPoint":117,"geoPoint":121,"contacts":122},"HCL - Groupement Hospitalier Est, Hôpital Femme Mère Enfant","Lyon",{"type":52,"coordinates":118},[119,120],4.84789,45.74906,{"lat":120,"lon":119},[123,125],{"name":124,"role":37,"phone":25,"phoneExt":25,"email":25},"Mona Massoud, MD",{"name":126,"role":33,"phone":25,"phoneExt":25,"email":25},"Mona MASSOUD",{"facility":128,"status":47,"city":129,"state":25,"zip":25,"country":49,"countryCode":50,"cosmosGeoPoint":130,"geoPoint":134,"contacts":135},"AP-HM Hôpital de la Conception","Marseille",{"type":52,"coordinates":131},[132,133],5.38107,43.29695,{"lat":133,"lon":132},[136,138],{"name":137,"role":37,"phone":25,"phoneExt":25,"email":25},"Blandine Courbière, MD",{"name":139,"role":33,"phone":25,"phoneExt":25,"email":25},"Blandine COURBIERE",{"facility":141,"status":47,"city":129,"state":25,"zip":25,"country":49,"countryCode":50,"cosmosGeoPoint":142,"geoPoint":144,"contacts":145},"AP-HM Hôpital Nord",{"type":52,"coordinates":143},[132,133],{"lat":133,"lon":132},[146,148],{"name":147,"role":37,"phone":25,"phoneExt":25,"email":25},"Julie Blanc, MD",{"name":149,"role":33,"phone":25,"phoneExt":25,"email":25},"Julie BLANC",{"facility":151,"status":47,"city":152,"state":25,"zip":25,"country":49,"countryCode":50,"cosmosGeoPoint":153,"geoPoint":157,"contacts":158},"CHU Montpellier","Montpellier",{"type":52,"coordinates":154},[155,156],3.87635,43.61093,{"lat":156,"lon":155},[159,161],{"name":160,"role":37,"phone":25,"phoneExt":25,"email":25},"Noémie Ranisavljevic, MD",{"name":162,"role":33,"phone":25,"phoneExt":25,"email":25},"Noémie RANISAVLJEVIC",{"facility":164,"status":47,"city":165,"state":25,"zip":25,"country":49,"countryCode":50,"cosmosGeoPoint":166,"geoPoint":170,"contacts":171},"CHRU Nancy","Nancy",{"type":52,"coordinates":167},[168,169],6.18496,48.68439,{"lat":169,"lon":168},[172,174],{"name":173,"role":37,"phone":25,"phoneExt":25,"email":25},"Catherine Zuili Lamy, MD",{"name":175,"role":33,"phone":25,"phoneExt":25,"email":25},"Catherine ZUILI LAMY",{"facility":177,"status":47,"city":178,"state":25,"zip":25,"country":49,"countryCode":50,"cosmosGeoPoint":179,"geoPoint":183,"contacts":184},"CHU Nantes","Nantes",{"type":52,"coordinates":180},[181,182],-1.55336,47.21725,{"lat":182,"lon":181},[185,187],{"name":186,"role":37,"phone":25,"phoneExt":25,"email":25},"Vincent Dochez, MD",{"name":188,"role":33,"phone":25,"phoneExt":25,"email":25},"Vincent DOCHEZ",{"facility":190,"status":47,"city":191,"state":25,"zip":25,"country":49,"countryCode":50,"cosmosGeoPoint":192,"geoPoint":196,"contacts":197},"CHU Nîmes","Nîmes",{"type":52,"coordinates":193},[194,195],4.35788,43.83665,{"lat":195,"lon":194},[198,200],{"name":199,"role":37,"phone":25,"phoneExt":25,"email":25},"Stéphanie Huberlant, MD",{"name":201,"role":33,"phone":25,"phoneExt":25,"email":25},"Stéphanie HUBERLANT",{"facility":203,"status":47,"city":204,"state":25,"zip":25,"country":49,"countryCode":50,"cosmosGeoPoint":205,"geoPoint":209,"contacts":210},"Groupe hospitalier St Joseph","Paris",{"type":52,"coordinates":206},[207,208],2.3488,48.85341,{"lat":208,"lon":207},[211,213],{"name":212,"role":37,"phone":25,"phoneExt":25,"email":25},"Elie Azria, MD",{"name":214,"role":33,"phone":25,"phoneExt":25,"email":25},"Elie AZRIA",{"facility":216,"status":217,"city":204,"state":25,"zip":25,"country":49,"countryCode":50,"cosmosGeoPoint":218,"geoPoint":220,"contacts":221},"Hôpital Armand - Trousseau","NOT_YET_RECRUITING",{"type":52,"coordinates":219},[207,208],{"lat":208,"lon":207},[222,224],{"name":223,"role":37,"phone":25,"phoneExt":25,"email":25},"Gilles Kayem, MD",{"name":225,"role":33,"phone":25,"phoneExt":25,"email":25},"Gilles KAYEM",{"facility":227,"status":47,"city":204,"state":25,"zip":25,"country":49,"countryCode":50,"cosmosGeoPoint":228,"geoPoint":230,"contacts":231},"Hôpital Cochin",{"type":52,"coordinates":229},[207,208],{"lat":208,"lon":207},[232,234],{"name":233,"role":37,"phone":25,"phoneExt":25,"email":25},"Vassilis Tsatsaris, MD",{"name":235,"role":33,"phone":25,"phoneExt":25,"email":25},"Vassilis TSATSARIS",{"facility":237,"status":47,"city":238,"state":25,"zip":25,"country":49,"countryCode":50,"cosmosGeoPoint":239,"geoPoint":243,"contacts":244},"CHI Poissy Saint Germain en Laye","Poissy",{"type":52,"coordinates":240},[241,242],2.04952,48.92902,{"lat":242,"lon":241},[245,247],{"name":246,"role":37,"phone":25,"phoneExt":25,"email":25},"Paul Berveiller, MD",{"name":248,"role":33,"phone":25,"phoneExt":25,"email":25},"Paul BERVEILLER",{"facility":250,"status":217,"city":251,"state":25,"zip":25,"country":49,"countryCode":50,"cosmosGeoPoint":252,"geoPoint":256,"contacts":257},"CHU Poitiers","Poitiers",{"type":52,"coordinates":253},[254,255],0.34348,46.58261,{"lat":255,"lon":254},[258,260],{"name":259,"role":37,"phone":25,"phoneExt":25,"email":25},"Aurélie Brossard Violeau, MD",{"name":261,"role":33,"phone":25,"phoneExt":25,"email":25},"Aurélie BROSSARD VIOLEAU",{"facility":263,"status":47,"city":264,"state":25,"zip":25,"country":49,"countryCode":50,"cosmosGeoPoint":265,"geoPoint":269,"contacts":270},"CHU Rennes","Rennes",{"type":52,"coordinates":266},[267,268],-1.67431,48.11109,{"lat":268,"lon":267},[271,273],{"name":272,"role":37,"phone":25,"phoneExt":25,"email":25},"Céline Pimentel, MD",{"name":274,"role":33,"phone":25,"phoneExt":25,"email":25},"Céline PIMENTEL",{"facility":276,"status":47,"city":277,"state":25,"zip":25,"country":49,"countryCode":50,"cosmosGeoPoint":278,"geoPoint":282,"contacts":283},"CHU Saint Etienne, Hôpital Nord","Saint-Etienne",{"type":52,"coordinates":279},[280,281],4.39,45.43389,{"lat":281,"lon":280},[284,286],{"name":285,"role":37,"phone":25,"phoneExt":25,"email":25},"Tiphaine Barjat, MD",{"name":287,"role":33,"phone":25,"phoneExt":25,"email":25},"Tiphaine BARJAT",{"facility":289,"status":47,"city":290,"state":25,"zip":25,"country":49,"countryCode":50,"cosmosGeoPoint":291,"geoPoint":295,"contacts":296},"CHU Strasbourg","Strasbourg",{"type":52,"coordinates":292},[293,294],7.74553,48.58392,{"lat":294,"lon":293},[297,299],{"name":298,"role":37,"phone":25,"phoneExt":25,"email":25},"Catherine Rongières, MD",{"name":300,"role":33,"phone":25,"phoneExt":25,"email":25},"Catherine RONGIERE",{"facility":302,"status":47,"city":303,"state":25,"zip":25,"country":49,"countryCode":50,"cosmosGeoPoint":304,"geoPoint":308,"contacts":309},"CHU Toulouse","Toulouse",{"type":52,"coordinates":305},[306,307],1.44367,43.60426,{"lat":307,"lon":306},[310,311],{"name":36,"role":37,"phone":25,"phoneExt":25,"email":39},{"name":32,"role":33,"phone":25,"phoneExt":25,"email":25},{"type":313,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100487333","phase-3-aspirin-for-the-prevention-of-preeclampsia-and-pregnancy-outcomes-after-assisted-reproductive-technology-100487333",false,"NCT05625724","Aspirin for the Prevention of Preeclampsia and Pregnancy Outcomes After Assisted Reproductive Technology","Aspirin for the Prevention of Preeclampsia and Pregnancy Outcomes in Nulliparous Women After Assisted Reproductive Technology. APPART","APPART","Inclusion Criteria:\n\n* Nulliparous women aged 18 years or more\n* Pregnancy following ART, including in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), oocyte donation or intrauterine insemination with sperm donor\n* Singleton pregnancy\n* Evolutive pregnancy between 9 and 14 weeks of gestation\n* Women affiliated to a French Social Security Insurance or equivalent social protection\n* Written informed consent\n\nExclusion Criteria:\n\n* Major fetal abnormality\n* Regular treatment with aspirin (including antiphospholipid syndrome)\n* Aspirin contraindications (allergy, von Willebrand disease, peptic ulceration, hemophilia)\n* Women protected by law.\n* Women included in another interventional study.","FEMALE","18 Years",{"count":325,"type":326},1164,"ESTIMATED","INTERVENTIONAL",[329],"PHASE3","This study seeks to validate the hypothesis that nulliparous pregnant women after Assisted Reproductive Technology (ART) are at high risk of preeclampsia and perinatal complications and represent a subgroup for which aspirin prophylaxis during pregnancy may be effective in the prevention of preterm preeclampsia and other perinatal adverse outcomes.",[332,333],"ART","Pre-Eclampsia","2026-05-04",{"date":336,"type":337},"2026-05-07","ACTUAL",{"date":339,"type":337},"2023-08-02",{"date":341,"type":326},"2029-05",{"name":5,"class":6},21]