[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100624701":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":31,"centralContacts":38,"locations":48,"responsibleParty":65,"collaborators":31,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":31,"eligibilityCriteria":75,"healthyVolunteers":71,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":31,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":51,"whyStopped":31,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"Oman Ministry of Health","OTHER_GOV",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"8mg Dexamethasone","EXPERIMENTAL","8mg\u002F2ml dexamethasone injection.",[13],"Drug: Dexamethasone 8Mg Solution for Injection",{"label":15,"type":10,"description":16,"interventionNames":17},"4mg Dexamethasone","4mg\u002F1ml Dexamethasone ampoule + 1ml of sterile normal saline for injection. Mixing dexamethasone with sterile normal saline for injection is considered safe and has no effect on drug potency and efficacy based on current evidence.",[18],"Drug: Dexamethasone 4 Mg\u002FmL Injectable Solution",{"label":20,"type":21,"description":22,"interventionNames":23},"Placebo","PLACEBO_COMPARATOR","2 ml of sterile normal saline for injection.",[24],"Drug: Saline (NaCl 0,9 %) (placebo)",[26,32,35],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"DRUG","Dexamethasone 4 Mg\u002FmL Injectable Solution","Syringe will be concealed. Submucosal injection will be adjacent to the surgical site in the buccal vestibule",[15],null,{"type":27,"name":33,"description":29,"armGroupLabels":34,"otherNames":31},"Dexamethasone 8Mg Solution for Injection",[9],{"type":27,"name":36,"description":29,"armGroupLabels":37,"otherNames":31},"Saline (NaCl 0,9 %) (placebo)",[20],[39,44],{"name":40,"role":41,"phone":42,"phoneExt":31,"email":43},"Shurooq Slim Al Hinai, BDS","CONTACT","+968 96148103","shurooqalhinai@gmail.com",{"name":45,"role":41,"phone":46,"phoneExt":31,"email":47},"Nasser Al Khaldi, Senior Consultant Prosth","+ 968 92898987","dent2020@gmail.com",[49],{"facility":50,"status":51,"city":52,"state":31,"zip":31,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Al Nahdha Hospital","RECRUITING","Muscat","Oman","OM",{"type":56,"coordinates":57},"Point",[58,59],58.40778,23.58413,{"lat":59,"lon":58},[62],{"name":63,"role":41,"phone":64,"phoneExt":31,"email":47},"Nasser Al Khaldi, Senior Consultant Prostho","+968 92898987",{"type":66,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"PRINCIPAL_INVESTIGATOR","Shurooq Al-Hinai","Principal Investigator","100624701","phase-3-comparative-efficacy-of-4-mg-vs-8-mg-submucosal-dexamethasone-in-postoperative-pain-management-after-dental-implant-surgery-a-randomized-double-blind-controlled-clinical-trial-100624701",false,"NCT07413055","Comparative Efficacy Of 4 mg VS. 8 mg Submucosal Dexamethasone In Postoperative Pain Management After Dental Implant Surgery: A Randomized Double-Blind Controlled Clinical Trial","Comparative Efficacy of 4 mg vs. 8 mg Submucosal Dexamethasone in Postoperative Pain Management After Dental Implant Surgery: A Randomized Double-Blind Controlled Clinical Trial","Inclusion Criteria:\n\n* Males \\& females\n* Age range (21-80)\n* ASA I \\& II according to (American Society of Anesthesiologists) classification\n* Single tooth implant\n* Type 3 \\& type 4 implant placement timing (Chen and Buser, 2009)\n\nExclusion Criteria:\n\n* Any known allergy to any medications which will be used in the study\n* Smokers\u002F Alcoholics\n* Pregnant and lactating women\n* Bone augmentation\u002F sinus lifting required during the surgery\n* The need of antibiotic prophylaxis","ALL","21 Years","80 Years",{"count":80,"type":81},138,"ESTIMATED","INTERVENTIONAL",[84],"PHASE3","This study aims to compare the effectiveness of 4mg and 8mg dexamethasone administered submucosally in reducing postoperative pain after dental implant surgery. Participants will be randomly assigned to receive either 4mg dexamethasone, 8mg dexamethasone, or a placebo (normal saline) at the surgical site.\n\nLater, postoperative pain will be assessed using a Visual Analog Scale at 6 hours after the surgery and daily for the next 6 days. Also the number of pain-relief tablets consumed after the surgery will be recorded.\n\nPreoperative anxiety will be assessed using Generalized Anxiety Disorder-7 (GAD-7) questionnaire to assess its association with postoperative pain scores.\n\nThe results of this study will help determine the optimal dose of dexamethasone that is effective for postoperative pain control following dental implant surgery.",[87],"Postoperative Pain",[89,90,91,92,93,94],"Dexamethasone","Dental implants","Postoperative pain","Submucosal injection","Analgesic consumption","Anxiety","2026-03-25",{"date":97,"type":98},"2026-03-30","ACTUAL",{"date":95,"type":81},{"date":101,"type":81},"2026-12-01",{"name":5,"class":6},1]