[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635749":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":38,"centralContacts":39,"locations":51,"responsibleParty":67,"collaborators":38,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":74,"sex":79,"minAge":80,"maxAge":38,"enrollmentInfo":81,"targetDuration":38,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":93,"overallStatus":99,"whyStopped":38,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Hospital General de Mexico","OTHER_GOV",[8,15,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Oral ferrous fumarate administered every 24 hours","ACTIVE_COMPARATOR","Administration of ferrous fumarate (each dose contains elemental iron, usually approximately 60 mg, together with ascorbic acid (vitamin C) in an amount of approximately 30 mg. In addition, it includes folic acid at a dose of approximately 400 mcg and vitamin B12 at approximately 8 mcg. Additional inactive ingredients may include excipients and coating agents to facilitate administration and absorption), administered every 24 hours.\n\nParticipants are instructed to take one tablet or capsule per day, preferably with food to improve absorption and minimize potential gastrointestinal discomfort. The duration of treatment is three months for the recovery of anemia.",[13,14],"Drug: Ferrous fumarate administered orally every 48 hours.","Drug: Liposomal iron formulation.",{"label":16,"type":10,"description":17,"interventionNames":18},"Ferrous fumarate administered orally every 48 hours.","Administration of ferrous fumarate (each dose contains elemental iron, usually approximately 60 mg, together with ascorbic acid (vitamin C) in an amount of approximately 30 mg. In addition, it includes folic acid at a dose of approximately 400 mcg and vitamin B12 at approximately 8 mcg. Additional inactive ingredients may include excipients and coating agents to facilitate administration and absorption), administered every 48 hours.",[19,14],"Drug: Oral ferrous fumarate administered every 24 hours",{"label":21,"type":10,"description":22,"interventionNames":23},"Liposomal iron formulation.","Administration of an oral supplement combining liposomal iron (19.20 mg of elemental iron), vitamin C (60 mg), and soluble fiber (350 mg). The formulation includes dehydrated glucose syrup, soluble corn fiber, iron in the form of ferric pyrophosphate, natural strawberry flavor, along with vitamins and coloring agents such as beet red and carminic acid.\n\nThe combination of liposomal iron, vitamin C, and soluble fiber is designed to enhance iron absorption in the body, facilitating its utilization in hemoglobin synthesis and other essential components. The supplement is administered orally once daily (every 24 hours) for a duration of three months.",[19,13],[25,30,34],{"type":26,"name":9,"description":11,"armGroupLabels":27,"otherNames":28},"DRUG",[16,21],[29],"A arm",{"type":26,"name":16,"description":17,"armGroupLabels":31,"otherNames":32},[21,9],[33],"B arm",{"type":26,"name":21,"description":22,"armGroupLabels":35,"otherNames":36},[16,9],[37],"C arm",null,[40,46],{"name":41,"role":42,"phone":43,"phoneExt":44,"email":45},"Christian Omar R. Peñafiel. PhD, MD, PhD","CONTACT","52+5523351588","+52","leukemiachop33@gmail.com",{"name":47,"role":42,"phone":48,"phoneExt":49,"email":50},"Ernesto V Carpintero, MD","52+7771358561","52","nerev16@gmail.com",[52],{"facility":53,"status":38,"city":54,"state":54,"zip":55,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"Hospital General de México \"Eduardo Liceaga\"","Mexico City","06720","Mexico","MX",{"type":59,"coordinates":60},"Point",[61,62],-99.12766,19.42847,{"lat":62,"lon":61},[65],{"name":47,"role":42,"phone":66,"phoneExt":49,"email":50},"52´+ 7771358561",{"type":68,"investigatorFullName":69,"investigatorTitle":70,"investigatorAffiliation":71,"oldNameTitle":38,"oldOrganization":38},"PRINCIPAL_INVESTIGATOR","Christian Omar Ramos-Peñafiel, MD, PhD","Medical Doctor, Haematologist, Head of Department at Hospital General de Mexico,,Editor in Chief \"Revista de Hematología de México\"","Hospital General de México Dr. Eduardo Liceaga","100635749","phase-3-comparison-of-ferrous-salt-vs-liposomal-iron-in-adult-women-with-iron-deficiency-anemia-100635749",false,"NCT07556731","Comparison of Ferrous Salt vs. Liposomal Iron in Adult Women With Iron-Deficiency Anemia","IDA","Inclusion Criteria:\n\n* Female patients of reproductive age (15 to 49 years) with a diagnosis of iron-deficiency anemia secondary to dysfunctional uterine bleeding.\n* Patients with iron-deficiency anemia who are treatment-naïve or whose last administration of iron therapy, either oral or parenteral, occurred at least three months prior to enrollment and who continue to have anemia.\n* Patients with a functional oral route.\n* Signed informed consent.\n\nExclusion Criteria:\n\n* Patients with abnormal uterine bleeding secondary to cancer\n* Severe intolerance to iron supplementation\n* Patients with gastritis or chronic use of proton pump inhibitors\n* Concomitant treatment with dietary supplements rich in calcium, magnesium, or zinc\n* Patients with endocrine disorders (hypothyroidism, hyperthyroidism)\n* Uncontrolled type 2 diabetes mellitus\n* Associated gastrointestinal bleeding\n* Patients with esophageal disorders","FEMALE","18 Years",{"count":82,"type":83},100,"ESTIMATED","INTERVENTIONAL",[86],"PHASE3","The goal of this study is to compare ferrous salt and liposomal iron for the treatment of iron-deficiency anemia in adult women. The study will also evaluate how well each treatment is tolerated.\n\nThe main questions this study aims to answer are:\n\nDoes liposomal iron increase hemoglobin levels as effectively as ferrous salt?\n\nAre there differences in side effects, especially gastrointestinal symptoms, between the treatments?\n\nDoes dosing ferrous salt every other day improve tolerance compared to daily dosing?\n\nResearchers will compare three oral iron treatment strategies to determine which approach provides the best balance between effectiveness and tolerability.\n\nParticipants will:\n\nBe adult women diagnosed with iron-deficiency anemia\n\nBe randomly assigned to one of three groups:\n\nDaily ferrous salt Ferrous salt taken every other day Daily liposomal iron Take the assigned iron treatment for 3 months Have blood tests at the beginning and end of the study to measure hemoglobin and iron levels Report any side effects or intolerance during treatment",[89,90,91,92],"Iron-deficiency Anemia (IDA)","Hemoglobin","Iron Deficiencies","Adverse Effect",[94,95,96,97,98],"Iron-deficiency anemia treatment comparision","Oral iron dosing","Liposomal iron","Iron replacement therapy","ferritin","NOT_YET_RECRUITING","2026-04-22",{"date":102,"type":103},"2026-04-29","ACTUAL",{"date":105,"type":83},"2026-05-01",{"date":107,"type":83},"2027-07-01",{"name":5,"class":6},1]