[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100491188":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":38,"responsibleParty":93,"collaborators":96,"id":103,"slug":104,"hasResults":105,"nctId":106,"briefTitle":107,"officialTitle":107,"acronym":18,"eligibilityCriteria":108,"healthyVolunteers":105,"sex":109,"minAge":110,"maxAge":111,"enrollmentInfo":112,"targetDuration":18,"studyType":115,"phases":116,"briefSummary":118,"conditions":119,"keywords":122,"overallStatus":40,"whyStopped":18,"lastUpdateSubmitDate":126,"lastUpdatePostDateStruct":127,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":135},{"fullName":5,"class":6},"American University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Dietary Intervention Group","EXPERIMENTAL","Subjects will undergo a 2-hour in-depth training via Zoom on how to follow the diet and will receive a binder with helpful information. They will be give the weekend to prepare and then will start the diet the following Monday, and will continue following it for 4 weeks before being reassessed in the lab.",[13],"Behavioral: Dietary Intervention",{"label":15,"type":16,"description":17,"interventionNames":18},"Waitlisted Control Group","NO_INTERVENTION","The waitlisted control group will follow their usual diet for one month and then will be reassessed (as a comparator group) before being trained on the dietary intervention which they will then follow for the next month.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"BEHAVIORAL","Dietary Intervention","This is a whole food, nutrient-dense diet that aims to remove exposure to specific food additives thought to have negative neurological effects, while also optimizing micronutrient intake.",[9],[26],{"name":27,"affiliation":5,"role":28},"Kathleen F Holton, PhD, MPH","PRINCIPAL_INVESTIGATOR",[30,35],{"name":31,"role":32,"phone":33,"phoneExt":18,"email":34},"Houra Taheri, PhD","CONTACT","202- 885-3810","htaheri@american.edu",{"name":27,"role":32,"phone":36,"phoneExt":18,"email":37},"202-885-3797","holton@american.edu",[39,55,72],{"facility":5,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"RECRUITING","Washington D.C.","District of Columbia","20016","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-77.03637,38.89511,{"lat":50,"lon":49},[53,54],{"name":31,"role":32,"phone":18,"phoneExt":18,"email":34},{"name":27,"role":28,"phone":18,"phoneExt":18,"email":18},{"facility":56,"status":40,"city":57,"state":58,"zip":59,"country":44,"countryCode":45,"cosmosGeoPoint":60,"geoPoint":64,"contacts":65},"Nova Southeastern University","Fort Lauderdale","Florida","33314",{"type":47,"coordinates":61},[62,63],-80.14338,26.12231,{"lat":63,"lon":62},[66,70],{"name":67,"role":32,"phone":68,"phoneExt":18,"email":69},"Oleksandra Shchebet","954-262-2896","oshchebe@nova.edu",{"name":71,"role":28,"phone":18,"phoneExt":18,"email":18},"Amanpreet Cheema, PhD",{"facility":73,"status":40,"city":74,"state":75,"zip":76,"country":44,"countryCode":45,"cosmosGeoPoint":77,"geoPoint":81,"contacts":82},"Boston University","Boston","Massachusetts","02118",{"type":47,"coordinates":78},[79,80],-71.05977,42.35843,{"lat":80,"lon":79},[83,87,91],{"name":84,"role":32,"phone":85,"phoneExt":18,"email":86},"Dylan Keating","617-358-2230","dmk13@bu.edu",{"name":88,"role":32,"phone":89,"phoneExt":18,"email":90},"Camryn Isemann","617-358-1717","camryns@bu.edu",{"name":92,"role":28,"phone":18,"phoneExt":18,"email":18},"Kimberly Sullivan, PhD",{"type":28,"investigatorFullName":94,"investigatorTitle":95,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Kathleen Holton","Associate Professor",[97,98,100,102],{"name":73,"class":6},{"name":99,"class":6},"Massachusetts General Hospital",{"name":101,"class":6},"Georgetown University",{"name":56,"class":6},"100491188","phase-3-confirmation-of-diet-as-a-treatment-for-gulf-war-illness-100491188",false,"NCT05675878","Confirmation of Diet as a Treatment for Gulf War Illness","Inclusion Criteria:\n\n* Males and Females of all races and ethnicities who are ≤75 yrs of age\n* Served in the 1990-1991 Persian Gulf War\n* Fulfill both Center for Disease Control (CDC) and Kansas definitions of Gulf War Illness\n* Stable medication regimen for ≥1 month and willing to keep medications and supplements stable throughout study participation\n\nExclusion Criteria:\n\n* Recent substance use disorder (past year)\n* Unwilling to stop using alcohol, tobacco (including vaping) and\u002For marijuana; or unwilling to change diet\n* Diagnosed seizure disorder or severe asthma requiring past hospitalization\n* Currently taking medication which affects glutamatergic or GABAergic neurotransmission (but can work with their physician to wean off of these medications prior to participating)","ALL","50 Years","75 Years",{"count":113,"type":114},160,"ESTIMATED","INTERVENTIONAL",[117],"PHASE3","This clinical trial aims to confirm previous findings from a smaller study which demonstrated significant improvements in all symptoms among veterans with Gulf War Illness after one month on the dietary intervention. The main objectives of this study are: 1) to confirm previous findings of treatment response to the diet in a larger and more diverse group; 2) to examine how changes in the nervous system may be the reason for improvement; and 3) to identify markers which change in the blood after one month on the diet. Participants will have baseline measures collected and then will be randomized into the intervention or wait-listed control group, which they will follow for one month before being reassessed.",[120,121],"Gulf War Syndrome","Gulf War Illness",[121,123,120,124,125],"GWI","Diet","Treatment","2024-07-05",{"date":128,"type":129},"2024-07-09","ACTUAL",{"date":131,"type":129},"2023-03-01",{"date":133,"type":114},"2025-12-30",{"name":5,"class":6},3]