[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100644144":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":27,"centralContacts":36,"locations":42,"responsibleParty":55,"collaborators":27,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":27,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":27,"maxAge":27,"enrollmentInfo":67,"targetDuration":27,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":45,"whyStopped":27,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Instituto do Coracao","OTHER_GOV",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"ESP Block Ropivacaine PCA group","ACTIVE_COMPARATOR","Local anesthetic solution group that received the solution with the local anesthetic in the ESP block and also in the patient-controlled analgesia pump. Perform the esp block, at the level of the fourth thoracic vertebra, administration of local anesthetic (25 ml of 0.25% ropivacaine in each side, respecting the toxic dose).After puncture and infusion of the initial dose, a catheter will be inserted on each side, also under ultrasound guidance and connected to a patient-controlled analgesia pump (PCA), with a corresponding bupivacaine solution programmed with a maintenance dose of 4ml \u002F Hr and bolus of 06 ml with the trigger firing.",[13,14],"Drug: Ropivacaine","Drug: Standard Postoperative Analgesics",{"label":16,"type":17,"description":18,"interventionNames":19},"ESP Block placebo PCA group","PLACEBO_COMPARATOR","Group that will serve as a comparison for blockade with analgesia. That is, this group had received a placebo solution. Perform the esp block, at the level of the fourth thoracic vertebra, and the content of the solution will be placebo (25 ml of saline \u002F 0.9% NaCl on each side). After puncture and infusion of the initial dose, a catheter will be inserted on each side, also under ultrasound guidance and connected to a patient-controlled analgesia pump (PCA), with 0.9% NaCl solution programmed with a maintenance dose at 4ml \u002F Hr and 06 ml bolus with trigger.",[14,20],"Drug: Placebo (0.9% Sodium Chloride)",[22,28,32],{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"DRUG","Ropivacaine","Bilateral Erector Spinae Plane (ESP) block performed at the T4 level using 25 mL of 0.25% ropivacaine per side, followed by continuous postoperative patient-controlled regional analgesia (PCA) pump programmed with ropivacaine (maintenance rate of 4 mL\u002Fh, demand bolus of 6 mL).",[9],null,{"type":23,"name":29,"description":30,"armGroupLabels":31,"otherNames":27},"Standard Postoperative Analgesics","Systemic multimodal analgesic regimen based on institutional protocols, consisting of scheduled and rescue oral and intravenous (IV) analgesics (such as dipyrone, NSAIDs, or opioids) as part of usual postoperative care.",[9,16],{"type":23,"name":33,"description":34,"armGroupLabels":35,"otherNames":27},"Placebo (0.9% Sodium Chloride)","Inactive saline solution (25 mL of 0.9% NaCl per side) administered during a sham bilateral ESP block at the T4 level, followed by a continuous postoperative PCA pump infusion of 0.9% NaCl (maintenance rate of 4 mL\u002Fh, demand bolus of 6 mL) to serve as a comparator.",[16],[37],{"name":38,"role":39,"phone":40,"phoneExt":27,"email":41},"JOAO ALBERTO PASTOR de OLIVEIRA, MD","CONTACT","+5511991700431","joaoalbertopastor@yahoo.com.br",[43],{"facility":44,"status":45,"city":46,"state":46,"zip":27,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":27},"InCor","RECRUITING","São Paulo","Brazil","BR",{"type":50,"coordinates":51},"Point",[52,53],-46.63611,-23.5475,{"lat":53,"lon":52},{"type":56,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":27,"oldOrganization":27},"PRINCIPAL_INVESTIGATOR","Filomena R B G Galas","Associate Professor of Anesthesiology at University São Paulo Medical School","100644144","phase-3-continuous-esp-block-in-patients-undergoing-cabg-surgery-100644144",false,"NCT07666178","Continuous ESP Block in Patients Undergoing CABG Surgery.","Continuous Erector Spinea Plane Block in Patients Undergoing Coronary Artery By-pass Graft Surgery.","Inclusion Criteria:\n\n* Consent to the free and informed consent term.\n* Patient undergoing coronary artery bypass graft surgery with cardiopulmonary bypass (CPB).\n* Preserved left ventricular global function (LVEF \\> 50%).\n\nExclusion Criteria:\n\n* Moderate or severe valvular dysfunction.\n* Previous anterior sternotomy.\n* Known allergy to the study drugs.\n* Complications during catheter insertion or block placement.\n* Pre-existing diagnosed chronic pain under treatment.\n* Concomitant use of drugs with a long half-life (induction and anesthetic maintenance doses will be standardized; patients taking medications with a long half-life are excluded to prevent bias in outcome assessment).\n* Concomitant administration of Magnesium Sulfate.","ALL",{"count":68,"type":69},78,"ESTIMATED","INTERVENTIONAL",[72],"PHASE3","This study addresses articles and studies related to the erector spinae plane (ESP) block and its technique, advantages and disadvantages, applicability, among others. It aims to provide more information about this block, which is relatively new, and how it can be explored in the anesthesiologist's routine, mainly inserted in the anesthesia scenario for cardiac surgery with a focus on postoperative analgesia.",[75],"Erector Spinae Plane Block",[77,78,79,80,81],"Spinae erector block","esp block","Analgesia","Continuous analgesia","block","2026-06-18",{"date":84,"type":85},"2026-06-24","ACTUAL",{"date":87,"type":85},"2024-12-12",{"date":89,"type":69},"2027-12-12",{"name":5,"class":6},1]