[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100422792":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":35,"locations":41,"responsibleParty":62,"collaborators":25,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":70,"eligibilityCriteria":71,"healthyVolunteers":66,"sex":72,"minAge":73,"maxAge":25,"enrollmentInfo":74,"targetDuration":25,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":43,"whyStopped":25,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"University Hospital, Brest","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"ICG group","EXPERIMENTAL","Patient receiving 2 or 3 intraoperative injections of indocyanine green.",[13],"Drug: ICG",{"label":15,"type":6,"description":16,"interventionNames":17},"Control group","Patient benefiting from the traditional surgical act",[18],"Procedure: Control group",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","ICG","During thyroidectomy surgery, the patient will received 2 or 3 injections of 5 mg as a bolus. The first one during the dissection of the first lobe, then during the dissection of the second lobe and finally if needed, a 3rd injection will be done at the end of the dissection.\n\nPatients will then be followed during 6 months.",[9],null,{"type":27,"name":15,"description":28,"armGroupLabels":29,"otherNames":25},"PROCEDURE","During thyroidectomy surgery, patients are treated according to traditional surgery with detection of parathyroids with the naked eyes.\n\nPatients will then be followed during 6 months.",[15],[31],{"name":32,"affiliation":33,"role":34},"Jean-Christophe LECLERE, PhD","CHRU de Brest","PRINCIPAL_INVESTIGATOR",[36],{"name":32,"role":37,"phone":38,"phoneExt":39,"email":40},"CONTACT","0298223630","+33","jean-christophe.leclere@chu-brest.fr",[42],{"facility":33,"status":43,"city":44,"state":25,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"RECRUITING","Brest","29609","France","FR",{"type":49,"coordinates":50},"Point",[51,52],-4.48628,48.39029,{"lat":52,"lon":51},[55,57,60],{"name":56,"role":37,"phone":25,"phoneExt":25,"email":25},"Jean-Christophe LECLERE",{"name":58,"role":59,"phone":25,"phoneExt":25,"email":25},"Gael POTARD","SUB_INVESTIGATOR",{"name":61,"role":59,"phone":25,"phoneExt":25,"email":25},"Julien PREVOT",{"type":63,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100422792","phase-3-contribution-of-icg-angiography-in-the-detection-of-parathyroids-and-the-prevention-of-hypoparathyroidism-post-total-thyroidectomy-100422792",false,"NCT04785443","Contribution of ICG Angiography in the Detection of Parathyroids and the Prevention of Hypoparathyroidism Post Total Thyroidectomy","Contribution of Indocyanine Green Angiography in the Detection of Parathyroids and the Prevention of Hypoparathyroidism Post Total Thyroidectomy","HYPOCAAVI","Inclusion Criteria:\n\n* Patient having to undergo a total thyroidectomy\n* Signed consent\n* Patient beneficiary of a social security regimen\n\nExclusion Criteria:\n\n* Minor patient under 18 years old\n* Major patient protected by law or unable to give informed consent\n* Pregnant or breastfeeding woman\n* Thyroidectomy totalization\n* History of thyroid or parathyroid surgery\n* Participation refusal\n* Known allergy to ICG\n* Woman of child-bearing age not using adequate method of contraception","ALL","18 Years",{"count":75,"type":76},242,"ESTIMATED","INTERVENTIONAL",[79],"PHASE3","* Hypoparathyroidism is the most common complication after a total thyroidectomy surgery. It becomes permanent after 6 months.\n* Untreated permanent hypoparathyroidism is a source of numerous complications in general and therefore requires lifelong replacement therapy resulting in a significant deterioration in quality of life.\n* The intraoperative use of indocyanine green (ICG) angiography has recently been described as a reliable means of detecting parathyroidism and predicting the risk of postoperative hypoparathyroidism.\n* This use could prove to be a way to preserve parathyroid in vivo and thus reduce post-operative hypoparathyroidism rates.",[82],"Thyroid Diseases",[84,85,86],"Hypocalcemia","Hypoparathyroidism","Angiography","2026-03-18",{"date":89,"type":90},"2026-03-19","ACTUAL",{"date":92,"type":90},"2021-06-22",{"date":94,"type":76},"2027-06-22",{"name":5,"class":6},1]