[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100583252":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":30,"centralContacts":39,"locations":49,"responsibleParty":62,"collaborators":30,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":30,"eligibilityCriteria":72,"healthyVolunteers":68,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":30,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":85,"overallStatus":92,"whyStopped":30,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Deep Parasternal Intercostal Plane Block","ACTIVE_COMPARATOR","Patients will receive bilateral deep parasternal intercostal plane block.",[13],"Procedure: Deep Parasternal intercostal plane block",{"label":15,"type":10,"description":16,"interventionNames":17},"Erector Spinae plane block","Patients will receive bilateral erector spinae plane block",[18],"Procedure: Erector Spinae Plane Block",{"label":20,"type":10,"description":21,"interventionNames":22},"conventional analgesic regimen","patients will receive conventional analgesic regimen",[23],"Drug: conventional analgesic regimen",[25,31,35],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"PROCEDURE","Deep Parasternal intercostal plane block","Patients will receive bilateral deep parasternal plane block using, 1mg\u002Fkg of 0.25% bupivacaine on each side under ultrasound guidance. The total dose of bupivacaine amounting to 2 mg\u002Fkg.",[9],null,{"type":26,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"Erector Spinae Plane Block","Patients will receive bilateral erector spinae plane block using, 1 mg\u002Fkg of 0.25% bupivacaine will be administered on each side under ultrasound guidance. The total dose of bupivacaine amounted to 2 mg\u002Fkg",[15],{"type":36,"name":20,"description":37,"armGroupLabels":38,"otherNames":30},"DRUG","Anesthesia will be induced with IV ketamine, 2 mg\u002Fkg, fentanyl, 2 µg\u002Fkg, and rocuronium 0.9 mg\u002Fkg, administered to facilitate endotracheal intubation.\n\nMaintenance of anesthesia will be achieved by isoflurane at an end tidal concentration of 1-1.5% in FiO2 of 0.5, intravenous fentanyl at a dose of 1 µg\u002Fkg in incremental dosage, and intravenous rocuronium 0.15 mg\u002Fkg administration according to nerve stimulator.",[20],[40,45],{"name":41,"role":42,"phone":43,"phoneExt":30,"email":44},"Sarah A. H. Bakr, Ms degree of Anesthesia","CONTACT","[202] 01062638487","sarahhanee@med.asu.edu.eg",{"name":46,"role":42,"phone":47,"phoneExt":30,"email":48},"Amin M Alansary, MD of Anesthesia","[202] 01007962192","aminalansary@yahoo.com",[50],{"facility":51,"status":30,"city":52,"state":30,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":30},"Faculty of Medicine, Ain Shams University","Cairo","11591","Egypt","EG",{"type":57,"coordinates":58},"Point",[59,60],31.24967,30.06263,{"lat":60,"lon":59},{"type":63,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"PRINCIPAL_INVESTIGATOR","Sarah Ahmed Hanee Abdelmohaimen Bakr","Assisstant Lecturer","100583252","phase-3-deep-parasternal-intercostal-plane-block-versus-erector-spinae-plane-block-in-pediatric-cardiac-patients-undergoing-primary-repair-of-septal-defects-via-median-sternotomy-100583252",false,"NCT06873906","Deep Parasternal Intercostal Plane Block Versus Erector Spinae Plane Block in Pediatric Cardiac Patients Undergoing Primary Repair of Septal Defects Via Median Sternotomy","Comparative Study Between Deep Parasternal Intercostal Plane Block Versus Erector Spinae Plane Block in Pediatric Cardiac Patients Undergoing Primary Repair of Septal Defects Via Median Sternotomy","Inclusion Criteria:\n\n* Pediatric patients with acyanotic heart disease\n* Patients with septal defect undergoing primary repair\n* ASA Ⅰ and Ⅱ\n\nExclusion Criteria:\n\n* Patient's guardian refusal of procedure or participation in the study.\n* Patients with hemodynamic instability\n* Preexisting infection at the block site\n* Allergy to local anesthetics\n* Psychiatric illness\n* Abnormal coagulation profile\n* Preoperative ejection fraction less than 35%\n* Recurrent ventricular arrhythmias\n* Emergency Surgery\n* Redo surgeries","ALL","1 Year","10 Years",{"count":77,"type":78},45,"ESTIMATED","INTERVENTIONAL",[81],"PHASE3","In this study we are aiming to compare the Erector Spinae Plane Block and the Deep Parasternal intercostal plane block as regard to their technique, application and outcome in order to describe the most suitable method for pediatric cardiac patients undergoing primary repair of septal defects\n\nThe primary outcome of this study will be the time of the first request for postoperative analgesics by FLACC pain scale more than 4 The secondary outcomes will be the total postoperative analgesic consumption, time for extubation, the incidence of nausea and vomiting, hemodynamic instability, onset of ambulation and any other complications on the first day after surgery\n\nParticipants will be enrolled in this double-blinded randomly allocated using computer-based randomization into three groups. Group 1 will receive bilateral deep parasternal intercostal plane block. Group 2 will receive bilateral erector spinae plane block. Group 3 will receive conventional analgesic regimen without having a regional block",[84],"Septal Defect",[86,87,88,89,90,91],"septal defect","acyanotic heart disease","median sternotomy","deep parasternal intercostal plane block","erector spinae plane block","eras","NOT_YET_RECRUITING","2025-03-07",{"date":95,"type":96},"2025-03-13","ACTUAL",{"date":98,"type":78},"2025-03-20",{"date":100,"type":78},"2026-04-01",{"name":5,"class":6},1]