[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100567226":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":30,"centralContacts":38,"locations":49,"responsibleParty":77,"collaborators":30,"id":81,"slug":82,"hasResults":83,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":87,"eligibilityCriteria":88,"healthyVolunteers":83,"sex":89,"minAge":90,"maxAge":91,"enrollmentInfo":92,"targetDuration":30,"studyType":95,"phases":96,"briefSummary":98,"conditions":99,"keywords":101,"overallStatus":51,"whyStopped":30,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":114},{"fullName":5,"class":6},"Al-Azhar University","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"group of control (C)","EXPERIMENTAL","receive 18 ml of normal saline only and serve as the control group.the normal saline will injected in the knee joint by the surgeon through the arthroscope after completing the procedure",[13],"Drug: Normal Saline (Placebo)",{"label":15,"type":10,"description":16,"interventionNames":17},"groups of Bupivacaine (B)","The 18ml 0.25% bupivacaine will injected intra articular in the knee joint by the surgeon through the arthroscope after completing the procedure",[18,19],"Drug: Bupivacaine 0.25%","Drug: Dexmedetomidine",{"label":21,"type":10,"description":22,"interventionNames":23},"groups of dexmedetomidine (D)","Dexmedetomidine 1 μg\u002Fkg will injected intra articular in the knee joint by the surgeon through the arthroscope after completing the procedure.",[19],[25,31,35],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"DRUG","Normal Saline (Placebo)","the 18 ml of normal saline will injected intra articular in the knee joint by the surgeon through the arthroscope after completing the procedure",[9],null,{"type":26,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"Bupivacaine 0.25%","the 18ml 0.25% bupivacaine. will injected intra articular in the knee joint by the surgeon through the arthroscope after completing the procedure",[15],{"type":26,"name":36,"description":22,"armGroupLabels":37,"otherNames":30},"Dexmedetomidine",[15,21],[39,45],{"name":40,"role":41,"phone":42,"phoneExt":43,"email":44},"Mohamed A. Mahmoud, MD","CONTACT","01002538320","002","mohamedali.226@azhar.edu.eg",{"name":46,"role":41,"phone":47,"phoneExt":43,"email":48},"Warda D.K. Ali, MD","012224668648","d.wardah8888@gmail.com",[50,67],{"facility":5,"status":51,"city":52,"state":30,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"RECRUITING","Asyut","71523","Egypt","EG",{"type":57,"coordinates":58},"Point",[59,60],31.18368,27.18096,{"lat":60,"lon":59},[63,65],{"name":64,"role":41,"phone":42,"phoneExt":43,"email":44},"Mohamed A. Mahmoud, M.D",{"name":66,"role":41,"phone":42,"phoneExt":43,"email":44},"Mohamed A Mahmoud, M.D",{"facility":5,"status":68,"city":52,"state":30,"zip":30,"country":54,"countryCode":55,"cosmosGeoPoint":69,"geoPoint":71,"contacts":72},"NOT_YET_RECRUITING",{"type":57,"coordinates":70},[59,60],{"lat":60,"lon":59},[73,75],{"name":74,"role":41,"phone":42,"phoneExt":43,"email":44},"Mohamed A. Mahmoud",{"name":76,"role":41,"phone":42,"phoneExt":43,"email":44},"Mohamed A Mahmoud",{"type":78,"investigatorFullName":79,"investigatorTitle":80,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"PRINCIPAL_INVESTIGATOR","Mohamed Ali Mahmoud","Lecturer of anesthesia, intensive care and pain management","100567226","phase-3-dexmedetomidine-and-bupivacaine-intra-articular-for-postoperative-analgesia-after-knee-arthroscopic-surgery-100567226",false,"NCT06665438","Dexmedetomidine and Bupivacaine Intra-articular for Postoperative Analgesia After Knee Arthroscopic Surgery","Impact of Dexmedetomidine Add to Intra-articular Bupivacaine for Post Operative Analgesia After Knee Arthroscopic Surgery","DEXMED","Inclusion Criteria:\n\n* ASA I-II patients\n* Either sex\n* Aged 18-65 years\n* Candidates for anterior cruciate ligament (ACL) reconstruction by knee arthroscopy\n* Exclusion Criteria:\n* the patients with kidney failure, liver failure, valvular and ischemic heart disease , high blood pressure, diabetes, history of infection and malignancy.\n* history of coagulation diseases, and history of drug allergies to used drugs.\n* those who consumed NSAIDs and analgesics 24 h before surgery were excluded from the study.","ALL","18 Years","65 Years",{"count":93,"type":94},75,"ESTIMATED","INTERVENTIONAL",[97],"PHASE3","The aim of this study to compare the analgesic effects of intraarticular dexmedetomidine added to bupivacaine with those of bupivacaine alone after knee arthroscopy",[100],"Post Operative Analgesia",[102,103,36,104],"Knee arthroscopy","Bupivacaine","Postoperative pain","2025-04-20",{"date":107,"type":108},"2025-04-22","ACTUAL",{"date":110,"type":108},"2024-12-01",{"date":112,"type":94},"2025-04",{"name":5,"class":6},2]