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Pavlov\u002FDepartment of Childhood Diseases with a course in hospital pediatrics","Ryazan","390026",{"type":44,"coordinates":197},[198,199],39.70415,54.62696,{"lat":199,"lon":198},[202,204],{"name":203,"role":31,"phone":25,"phoneExt":25,"email":25},"Andrey Dmitriev",{"name":205,"role":53,"phone":25,"phoneExt":25,"email":25},"Andrey Dmitriev, MD, PhD",{"facility":207,"status":38,"city":208,"state":25,"zip":209,"country":41,"countryCode":42,"cosmosGeoPoint":210,"geoPoint":214,"contacts":215},"Children's City Polyclinic # 44","Saint Petersburg","191144",{"type":44,"coordinates":211},[212,213],30.31413,59.93863,{"lat":213,"lon":212},[216,218],{"name":217,"role":31,"phone":25,"phoneExt":25,"email":25},"Andrey Kamaev, MD, PhD",{"name":217,"role":53,"phone":25,"phoneExt":25,"email":25},{"facility":220,"status":112,"city":208,"state":25,"zip":221,"country":41,"countryCode":42,"cosmosGeoPoint":222,"geoPoint":224,"contacts":225},"Saint Petersburg State Pediatric University\u002FDepartment of Infectious Diseases of Adults and Epidemiology","194100",{"type":44,"coordinates":223},[212,213],{"lat":213,"lon":212},[226,228],{"name":227,"role":31,"phone":25,"phoneExt":25,"email":25},"Elena Esaulenko, Prof.",{"name":227,"role":53,"phone":25,"phoneExt":25,"email":25},{"facility":230,"status":38,"city":208,"state":25,"zip":231,"country":41,"countryCode":42,"cosmosGeoPoint":232,"geoPoint":234,"contacts":235},"LLC \"Zvezdnaya Clinic\"","196158",{"type":44,"coordinates":233},[212,213],{"lat":213,"lon":212},[236,238],{"name":237,"role":31,"phone":25,"phoneExt":25,"email":25},"Dmitry Shkarbul, MD",{"name":237,"role":53,"phone":25,"phoneExt":25,"email":25},{"facility":240,"status":38,"city":208,"state":25,"zip":241,"country":41,"countryCode":42,"cosmosGeoPoint":242,"geoPoint":244,"contacts":245},"Children's City Polyclinic # 35","196191",{"type":44,"coordinates":243},[212,213],{"lat":213,"lon":212},[246,248],{"name":247,"role":31,"phone":25,"phoneExt":25,"email":25},"Tatyana Antonova, MD, PhD",{"name":247,"role":53,"phone":25,"phoneExt":25,"email":25},{"facility":250,"status":38,"city":208,"state":25,"zip":251,"country":41,"countryCode":42,"cosmosGeoPoint":252,"geoPoint":254,"contacts":255},"Federal Scientific and Clinical Center for Infectious Diseases of the Federal Medical and Biological Agency","197022",{"type":44,"coordinates":253},[212,213],{"lat":213,"lon":212},[256,258],{"name":257,"role":31,"phone":25,"phoneExt":25,"email":25},"Konstantin Ermolenko, MD, PhD",{"name":257,"role":53,"phone":25,"phoneExt":25,"email":25},{"facility":260,"status":38,"city":208,"state":25,"zip":261,"country":41,"countryCode":42,"cosmosGeoPoint":262,"geoPoint":264,"contacts":265},"City Polyclinic # 3","199155",{"type":44,"coordinates":263},[212,213],{"lat":213,"lon":212},[266,268],{"name":267,"role":31,"phone":25,"phoneExt":25,"email":25},"Gleb Kondratiev, MD",{"name":267,"role":53,"phone":25,"phoneExt":25,"email":25},{"facility":270,"status":38,"city":208,"state":25,"zip":271,"country":41,"countryCode":42,"cosmosGeoPoint":272,"geoPoint":274,"contacts":275},"City Polyclinic # 4","199178",{"type":44,"coordinates":273},[212,213],{"lat":213,"lon":212},[276,278],{"name":277,"role":31,"phone":25,"phoneExt":25,"email":25},"Natalia Soroka, MD, PhD",{"name":277,"role":53,"phone":25,"phoneExt":25,"email":25},{"facility":280,"status":38,"city":281,"state":25,"zip":282,"country":41,"countryCode":42,"cosmosGeoPoint":283,"geoPoint":287,"contacts":288},"Samara Regional Children's Clinical Hospital named after N.N. 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Ogarev\u002FDepartment of Pediatrics","Saransk","430005",{"type":44,"coordinates":303},[304,305],45.17166,54.18485,{"lat":305,"lon":304},[308,310],{"name":309,"role":31,"phone":25,"phoneExt":25,"email":25},"Larisa Balykova, Prof.",{"name":309,"role":53,"phone":25,"phoneExt":25,"email":25},{"facility":312,"status":105,"city":313,"state":25,"zip":314,"country":41,"countryCode":42,"cosmosGeoPoint":315,"geoPoint":319,"contacts":25},"Saratov City Children's Clinical Hospital","Saratov","410064",{"type":44,"coordinates":316},[317,318],45.9901,51.54048,{"lat":318,"lon":317},{"facility":321,"status":38,"city":322,"state":25,"zip":323,"country":41,"countryCode":42,"cosmosGeoPoint":324,"geoPoint":328,"contacts":329},"Bashkir State Medical University\u002FDepartment of Outpatient and Emergency Pediatrics","Ufa","450008",{"type":44,"coordinates":325},[326,327],55.96779,54.74306,{"lat":327,"lon":326},[330,332],{"name":331,"role":31,"phone":25,"phoneExt":25,"email":25},"Lyudmila Yakovleva, Prof.",{"name":331,"role":53,"phone":25,"phoneExt":25,"email":25},{"facility":334,"status":38,"city":335,"state":25,"zip":336,"country":41,"countryCode":42,"cosmosGeoPoint":337,"geoPoint":341,"contacts":342},"Yaroslavl State Medical University\u002FDepartment of Pediatrics, INPO","Yaroslavl","150000",{"type":44,"coordinates":338},[339,340],39.87368,57.62987,{"lat":340,"lon":339},[343,345],{"name":344,"role":31,"phone":25,"phoneExt":25,"email":25},"Elena Shubina, MD, PhD",{"name":344,"role":53,"phone":25,"phoneExt":25,"email":25},{"facility":347,"status":38,"city":335,"state":25,"zip":348,"country":41,"countryCode":42,"cosmosGeoPoint":349,"geoPoint":351,"contacts":352},"Clinical Hospital # 2","150030",{"type":44,"coordinates":350},[339,340],{"lat":340,"lon":339},[353,355],{"name":354,"role":31,"phone":25,"phoneExt":25,"email":25},"Irina Melnikova, Prof.",{"name":354,"role":53,"phone":25,"phoneExt":25,"email":25},{"facility":357,"status":38,"city":358,"state":25,"zip":359,"country":41,"countryCode":42,"cosmosGeoPoint":360,"geoPoint":364,"contacts":365},"Children's City Clinical Hospital # 11","Yekaterinburg","620028",{"type":44,"coordinates":361},[362,363],60.61529,56.85733,{"lat":363,"lon":362},[366,368],{"name":367,"role":31,"phone":25,"phoneExt":25,"email":25},"Sophia Tsarkova, Prof.",{"name":367,"role":53,"phone":25,"phoneExt":25,"email":25},{"facility":370,"status":38,"city":358,"state":25,"zip":359,"country":41,"countryCode":42,"cosmosGeoPoint":371,"geoPoint":373,"contacts":374},"Ural State Medical University\u002FDepartment of Infectious Diseases, Phthisiology and Pulmonology",{"type":44,"coordinates":372},[362,363],{"lat":363,"lon":362},[375,377],{"name":376,"role":31,"phone":25,"phoneExt":25,"email":25},"Alebay Sabitov, Prof.",{"name":376,"role":53,"phone":25,"phoneExt":25,"email":25},{"type":379,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100606096","phase-3-efficacy-and-safety-of-rengalin-in-the-treatment-of-arvi-cough-in-children-100606096",false,"NCT07171099","Efficacy and Safety of Rengalin in the Treatment of ARVI Cough in Children","Multicenter, Double-blind, Placebo-controlled, Randomized, Parallel-group Clinical Trial of the Efficacy and Safety of Rengalin in the Treatment of Cough in Acute Viral Upper Respiratory Tract Infections Tract Infections in Children During the Epidemic Growth of Influenza and ARVI","Inclusion Criteria:\n\n1. Outpatients of both genders aged over 6 months and under 3 years.\n2. Clinically confirmed diagnosis of acute viral upper respiratory tract infections (acute pharyngitis, nasopharyngitis, tonsillitis, laryngitis, laryngotracheitis, tracheitis, acute viral respiratory infection of multiple and unspecified localization) during the epidemic growth of influenza and ARVI.\n3. Dry (non-productive) cough lasting at least 24 hours but not more than 72 hours.\n4. Total (day and night) cough severity score of 6 or more.\n5. Availability of a patient information sheet and an informed consent form for participation in the clinical trial signed by one of the patient's parents\u002Fadoptive parents.\n\nExclusion Criteria:\n\n1. Presence of the following diseases at the time of inclusion in the clinical trial:\n\n   1.1 Inflammatory processes in the lower respiratory tract. 1.2 Grade III adenoid hypertrophy. 1.3 Chronic adenoiditis. 1.4 Postnasal drip syndrome. 1.5 Gastroesophageal reflux. 1.6 Bronchial asthma. 1.7 Cystic fibrosis. 1.8 Primary ciliary dyskinesia 1.9 Bronchopulmonary dysplasia 1.10 Malformations of the respiratory and ENT organs 1.11 Other chronic lung diseases. 1.12 Primary\u002Fsecondary immunodeficiency. 1.13 Oncological disease of any localization.\n2. Suspected bacterial infection of any localization, including pneumonia, sinusitis, otitis media.\n3. Allergic rhinitis.\n4. Bronchial obstruction syndrome.\n5. Acute obstructive laryngitis \\[croup\\] and epiglottitis.\n6. Congenital heart defects with hypervolemia in pulmonary circulation.\n7. Acute respiratory failure.\n8. Inflammatory, degenerative, demyelinating diseases of the central nervous system, polyneuropathies, epilepsy.\n9. Exacerbation or decompensation of chronic diseases affecting the patient's ability to participate in a clinical trial.\n10. Presence of allergy\u002Fhypersensitivity to any components of the medicines used in the treatment.\n11. Taking medications listed in the section \"Prohibited Concomitant Therapy\" within 4 weeks prior to inclusion in the study.\n12. Patients whose parents\u002Fadoptive parents, from the investigator's point of view, will not comply with observation requirements during the study or with the administration of study drugs.\n13. Participation in other clinical trials within 3 months prior to inclusion in this trial.\n14. A patient's parent\u002Fadoptive parent is related to on-site research personnel directly involved in the trial, or is the immediate family member of the investigator. 'Immediate family members' mean spouses, parents, children, or siblings, whether related or adopted.\n15. The patient's parent\u002Fadoptive parent is employed by OOO \"NPF \"MATERIA MEDICA HOLDING\", i.e., is an employee of the company, a temporary contract employee, or a designated official responsible for conducting the trial or their immediate family member.","ALL","6 Months","3 Years",{"count":391,"type":392},264,"ESTIMATED","INTERVENTIONAL",[395],"PHASE3","The goal of this clinical trial is to evaluate the efficacy and safety of liquid dosage form of Rengalin in the treatment of cough in acute viral upper respiratory tract infections infections in children in during the epidemic growth of influenza and ARVI. The main questions it aims to answer are:\n\nInvestigators will compare the liquid dosage form of Rengalin to a placebo (a look-alike substance that contains no drug) to see if Rengalin in the liquid dosage form works for cough in acute viral upper respiratory tract infections in children.\n\nParticipants will:\n\nTake the liquid dosage form of Rengalin or placebo per os 5 ml per administration 3 times a day for 7 days.",[398],"Cough",[398,400,401],"Upper respiratory infection","Children from 6 months to 3 years","2026-02-11",{"date":404,"type":405},"2026-02-13","ACTUAL",{"date":407,"type":405},"2025-10-03",{"date":409,"type":392},"2028-12-31",{"name":5,"class":6},30]