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Currently on the recommended (as per label) dosage regimen of anti-C5 antibody treatment, for at least 3 months prior to entering the screening period.\n* In the opinion of the investigator the participant has responded to anti-C5 antibodytreatment prior to screening and has clinical evidence of response (in absence of PE\u002FPI) during the Screening period.\n\nClinical evidence of response to anti-C5 antibody treatment (in absence of PE\u002FPI) confirmed during the Screening period by central laboratory at two visits 12 weeks apart. Clinical evidence of response is defined as:\n\n1. Hematological normalization in platelet count ≥150 x 10\\^9\u002FL and LDH below upper limit of normal \\[ULN\\], and\n2. 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