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Phenotype","A Phase 2b\u002FPhase 3, Randomized, Double-blind, Placebocontrolled, Multicenter Study, to Investigate the Efficacy and Safety of Lunsekimig in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype","PERSEPHONE","Inclusion Criteria:\n\n* Between 40 to 80 years of age\n* Physician diagnosed chronic obstructive pulmonary disease (COPD) ≥1 year\n* Post-bronchodilator forced expiratory volume in 1 second (post-BD FEV1) ≥ 20% and ≤ 70% of predicted value and FEV1\u002FFVC (forced expiratory volume in 1 second \u002Fforced vital capacity) \\\u003C0.70\n* Former or current smokers ≥10 pack-years\n* Chronic Airways Assessment Test (CAAT) ≥10\n* ≥2 moderate or ≥1 severe COPD exacerbations in the prior year\n* Triple (ICS+LABA+LAMA) COPD therapy ≥12 consecutive weeks\n* EOS (blood eosinophil count) ≥ 150 cells\u002FμL\n* 18.0 ≤ Body Mass Index ≤ 40.0 kg\u002Fm2\n\nExclusion Criteria:\n\nParticipants are excluded from the study if any of the following criteria apply:\n\n* Asthma, including pediatric asthma, or asthma-COPD overlap syndrome (ACOS)\n* Significant pulmonary disease other than COPD\n* Long-term oxygen therapy \\>4.0 L\u002Fmin or requirement of \\>2.0 L\u002Fmin to maintain oxygen saturation \\>88% at rest\n* Unstable disorder that can impact participants safety or study outcomes\n* Active or incompletely treated tuberculosis\n* Current or past malignancies\n* Concomitant therapies:\n\n  * long-term macrolides or phosphodiesterase Type 3 (PDE-3) or PDE-4 inhibitors unless on stable therapy for \\>6 months\n  * any biologic therapy or systemic immunosuppressant within 4 months or 5 half-lives prior to Screening\n\nThe above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial","ALL","40 Years","80 Years",{"count":1922,"type":1923},942,"ESTIMATED","INTERVENTIONAL",[1926],"PHASE3","This is a parallel, 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