[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100530674":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":32,"centralContacts":36,"locations":42,"responsibleParty":62,"collaborators":31,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":31,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":73,"maxAge":31,"enrollmentInfo":74,"targetDuration":31,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":84,"overallStatus":44,"whyStopped":31,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Spray coag mode","ACTIVE_COMPARATOR","After initial mucosal incision, Endoscopic submucosal dissection will be performed using Spray coag mode using ERBE VIO 3 generator (effect 3-3.5)",[13],"Procedure: endoscopic submucosal dissection using SPRAY COAG mode",{"label":15,"type":10,"description":16,"interventionNames":17},"Precisect mode","After initial mucosal incision, Endoscopic submucosal dissection will be performed using Precisect mode using ERBE VIO 3 generator (effect 4.5-5)",[18],"Procedure: endoscopic submucosal dissection using Precisect mode",[20,27],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","endoscopic submucosal dissection using SPRAY COAG mode","After initial mucosal incision, submucosal dissection will be performed down to 2cm below the cardia using Spray coag mode using ERBE VIO3 generator and a Hybrid knife (T-type) aided by ERBEJET for submucosal injection",[9],[26],"POEM",{"type":21,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"endoscopic submucosal dissection using Precisect mode","After initial mucosal incision, submucosal dissection will be performed down to 2cm below the cardia using Precisect mode using ERBE VIO3 generator and a Hybrid knife (T-type) aided by ERBEJET for submucosal injection",[15],null,[33],{"name":34,"affiliation":5,"role":35},"hany shehab","PRINCIPAL_INVESTIGATOR",[37],{"name":38,"role":39,"phone":40,"phoneExt":31,"email":41},"hany Shehab, MD, FRCP","CONTACT","+201111111071","h.shehab@kasralainy.edu.eg",[43],{"facility":5,"status":44,"city":45,"state":31,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"RECRUITING","Cairo","11562","Egypt","EG",{"type":50,"coordinates":51},"Point",[52,53],31.24967,30.06263,{"lat":53,"lon":52},[56,60],{"name":57,"role":39,"phone":58,"phoneExt":31,"email":59},"Hany M Shehab, MD","01111111071","H.shehab@kasralainy.edu.eg",{"name":61,"role":35,"phone":31,"phoneExt":31,"email":31},"Hany M Shehab, FRCP",{"type":35,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"Hany Shehab","professor","100530674","phase-3-electrosurgical-modes-for-endoscopic-submucosal-dissection-in-peroral-endoscopic-esophageal-myotomy-100530674",false,"NCT06189859","Electrosurgical Modes for Endoscopic Submucosal Dissection in Peroral Endoscopic Esophageal Myotomy","Electrosurgical Modes for Endoscopic Submucosal Dissection in Peroral Endoscopic Esophageal Myotomy: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients undergoing POEM procedure for any esophageal motility disorder\n* Esophageal motility disorder confirmed by high-resolution manometry and gastroscopy\n\nExclusion Criteria:\n\n* Esophageal varices\n* Esophageal neoplasms\n* Non-correctable coagulopathy\n* Failure to provide an informed consent","ALL","18 Years",{"count":75,"type":76},52,"ESTIMATED","INTERVENTIONAL",[79],"PHASE3","Peroral endoscopic esophagel myotomy (POEM) is a third space endoscopy technique that depends on creating a submucosal tunnel to expose the esophageal muscle and eventually perform an esophageal myotomy. Submucosal dissection can be performed using numerous electrosurgical modes. Spray coagulation has been anecdotally favored by many endoscopists due to its high coagulation power and assumed safety. Recently, Precisect mode has been developed, it has theoretical advantages of very minimal tissue penetration and minimal to no charring effect. In this trial, the investigators compare the efficacy and safety of both electrosurgical modes in POEM procedures.",[82,83],"Achalasia","Achalasia Cardia",[85,26,86,87,88],"achalasia","ELECTROSURGERY","SPRAY COAGULATION","PERORALENDOSCOPIC ESOPHAGEAL MYOTOMY","2025-05-08",{"date":91,"type":92},"2025-05-13","ACTUAL",{"date":94,"type":92},"2024-03-16",{"date":96,"type":76},"2025-08",{"name":5,"class":6},1]