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Centro de Pesquisas Clínicas em Oncologia (CPCO)","RECRUITING","Cachoeiro de Itapemirim","Espírito Santo","29.308-065","Brazil","BR",{"type":60,"coordinates":61},"Point",[62,63],-41.11278,-20.84889,{"lat":63,"lon":62},[66],{"name":67,"role":38,"phone":44,"phoneExt":44,"email":44},"Sabina Bandeira Aleixo",{"facility":69,"status":53,"city":70,"state":71,"zip":72,"country":57,"countryCode":58,"cosmosGeoPoint":73,"geoPoint":77,"contacts":78},"Santa Casa de Misericórdia da Bahia - Hospital Santa Izabel","Salvador","Estado de Bahia","400.50-410",{"type":60,"coordinates":74},[75,76],-38.49096,-12.97563,{"lat":76,"lon":75},[79],{"name":80,"role":38,"phone":44,"phoneExt":44,"email":44},"Daniela Galvão Barros de Oliveira",{"facility":82,"status":53,"city":83,"state":84,"zip":85,"country":57,"countryCode":58,"cosmosGeoPoint":86,"geoPoint":90,"contacts":91},"Centro de Pesquisa do Hospital Araújo Jorge","Goiânia","Goiás","74.605-010",{"type":60,"coordinates":87},[88,89],-49.25389,-16.67861,{"lat":89,"lon":88},[92],{"name":93,"role":38,"phone":44,"phoneExt":44,"email":44},"Geraldo Silva Queiroz",{"facility":95,"status":53,"city":96,"state":97,"zip":98,"country":57,"countryCode":58,"cosmosGeoPoint":99,"geoPoint":103,"contacts":104},"ICTR - 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Instituto de Medicina Integral Professor Fernando Figueira","Recife","Pernambuco","50.070-902",{"type":60,"coordinates":131},[132,133],-34.88111,-8.05389,{"lat":133,"lon":132},[136],{"name":137,"role":38,"phone":44,"phoneExt":44,"email":44},"Andréa Lopes Ponte de Souza",{"facility":139,"status":53,"city":127,"state":128,"zip":140,"country":57,"countryCode":58,"cosmosGeoPoint":141,"geoPoint":143,"contacts":144},"Hospital Universitário Oswaldo Cruz (UNIPECLIN)","50.110-130",{"type":60,"coordinates":142},[132,133],{"lat":133,"lon":132},[145],{"name":146,"role":38,"phone":44,"phoneExt":44,"email":44},"Thiago Lourenço Apolinário",{"facility":148,"status":53,"city":149,"state":150,"zip":151,"country":57,"countryCode":58,"cosmosGeoPoint":152,"geoPoint":156,"contacts":157},"HINJA - Hospital Jardim Amália","Volta Redonda","Rio de Janeiro","27.251-260",{"type":60,"coordinates":153},[154,155],-44.10417,-22.52306,{"lat":155,"lon":154},[158],{"name":159,"role":38,"phone":44,"phoneExt":44,"email":44},"Heloísa Magda Resende",{"facility":161,"status":53,"city":162,"state":163,"zip":164,"country":57,"countryCode":58,"cosmosGeoPoint":165,"geoPoint":169,"contacts":170},"HCPA - Hospital de Clinicas de Porto Alegre","Porto Alegre","Rio Grande do Sul","90.035-903",{"type":60,"coordinates":166},[167,168],-51.23019,-30.03283,{"lat":168,"lon":167},[171],{"name":172,"role":38,"phone":44,"phoneExt":44,"email":44},"Pedro Emanuel Rubini Liedke",{"facility":174,"status":53,"city":175,"state":176,"zip":177,"country":57,"countryCode":58,"cosmosGeoPoint":178,"geoPoint":182,"contacts":183},"CEPON - Centro de Pesquisas Oncológicas","Florianópolis","Santa Catarina","88.034-000",{"type":60,"coordinates":179},[180,181],-48.54917,-27.59667,{"lat":181,"lon":180},[184],{"name":185,"role":38,"phone":44,"phoneExt":44,"email":44},"Yeni Verônica Nerón",{"facility":187,"status":53,"city":188,"state":189,"zip":190,"country":57,"countryCode":58,"cosmosGeoPoint":191,"geoPoint":195,"contacts":196},"Hospital de Amor de Barretos","Barretos","São Paulo","14.784-400",{"type":60,"coordinates":192},[193,194],-48.56778,-20.55722,{"lat":194,"lon":193},[197],{"name":198,"role":38,"phone":44,"phoneExt":44,"email":44},"Cristiano de Pádua Souza",{"facility":200,"status":53,"city":201,"state":189,"zip":202,"country":57,"countryCode":58,"cosmosGeoPoint":203,"geoPoint":207,"contacts":208},"UNESP - Faculdade de Medicina da Universidade Estadual Paulista (UPECLIN)","Botucatu","18.618-686",{"type":60,"coordinates":204},[205,206],-48.445,-22.88583,{"lat":206,"lon":205},[209],{"name":210,"role":38,"phone":44,"phoneExt":44,"email":44},"Ana Lucia Coradazzi",{"facility":212,"status":53,"city":213,"state":189,"zip":214,"country":57,"countryCode":58,"cosmosGeoPoint":215,"geoPoint":219,"contacts":220},"Faculdade de Ciências Médicas da Unicamp","Campinas","13.083-881",{"type":60,"coordinates":216},[217,218],-47.06083,-22.90556,{"lat":218,"lon":217},[221],{"name":222,"role":38,"phone":44,"phoneExt":44,"email":44},"Susana Oliveira Botelho Ramalho",{"facility":224,"status":53,"city":225,"state":189,"zip":226,"country":57,"countryCode":58,"cosmosGeoPoint":227,"geoPoint":231,"contacts":232},"Hospital de Amor Jales - Hospital de Câncer de Barretos","Jales","15.706-396",{"type":60,"coordinates":228},[229,230],-50.54583,-20.26889,{"lat":230,"lon":229},[233],{"name":234,"role":38,"phone":44,"phoneExt":44,"email":44},"Túlio Samara Rodrigues de Almeida Lucas Furquim",{"facility":236,"status":53,"city":150,"state":44,"zip":237,"country":57,"countryCode":58,"cosmosGeoPoint":238,"geoPoint":242,"contacts":243},"INCA - Instituto Nacional de Câncer","20.230-130",{"type":60,"coordinates":239},[240,241],-43.18223,-22.90642,{"lat":241,"lon":240},[244],{"name":245,"role":38,"phone":44,"phoneExt":44,"email":44},"Rodrigo Moura Araújo",{"facility":247,"status":53,"city":189,"state":44,"zip":248,"country":57,"countryCode":58,"cosmosGeoPoint":249,"geoPoint":253,"contacts":254},"ICESP - Instituto do Câncer do Estado de São Paulo","01.246-000",{"type":60,"coordinates":250},[251,252],-46.63611,-23.5475,{"lat":252,"lon":251},[255],{"name":256,"role":38,"phone":44,"phoneExt":44,"email":44},"Laura Testa",{"facility":258,"status":53,"city":189,"state":44,"zip":259,"country":57,"countryCode":58,"cosmosGeoPoint":260,"geoPoint":262,"contacts":263},"IBCC Oncologia - Núcleo de Pesquisa São Camilo","04.014-002",{"type":60,"coordinates":261},[251,252],{"lat":252,"lon":251},[264],{"name":265,"role":38,"phone":44,"phoneExt":44,"email":44},"Lilian Arruda do Rêgo Barros",{"type":267,"investigatorFullName":44,"investigatorTitle":44,"investigatorAffiliation":44,"oldNameTitle":44,"oldOrganization":44},"SPONSOR",[269],{"name":37,"class":270},"UNKNOWN","100404004","phase-3-evaluation-of-sequencing-of-anthracyclines-and-taxanes-for-locally-advanced-her2-negative-breast-cancer-100404004",false,"NCT04540692","Evaluation of Sequencing of Anthracyclines and Taxanes for Locally Advanced HER2-negative Breast Cancer","NEOSAMBA Clinical Trial - Stage I","NEOSAMBA","Inclusion Criteria:\n\n* Female participants, with at least 18 years old on the day of signing the free and informed consent;\n* Invasive breast carcinoma stage III (RH positive) or IIB\u002FIII (RH negative), according to TNM 8th edition; Histologically confirmed diagnosis of invasive breast carcinoma (with any histology), HER-2 negative;\n* The participant (or legally acceptable representative, if applicable) provides written informed consent for the study;\n* The participant must agree to use a contraceptive as detailed in Appendix B of this protocol during the treatment period and for at least 120 days after the last dose of the study treatment;\n* Have a functional capacity according to the Eastern Cooperative Oncology Group (ECOG) from 0 to 2. The evaluation of the ECOG must be carried out within 7 days before the inclusion date.\n* Have adequate organic function. The samples must be collected within 60 days before the start of the study treatment;\n* Have adequate cardiac function as assessed by echocardiogram or MUGA performed up to 60 days before the start of treatment under study.\n\nExclusion Criteria:\n\n\\- Individuals who do not meet the inclusion criteria above-mentioned.","FEMALE","18 Years",{"count":282,"type":283},444,"ESTIMATED","INTERVENTIONAL",[286],"PHASE3","Phase III randomized clinical trial evaluating the sequencing of anthracyclines and taxanes in neoadjuvant therapy for locally advanced HER2-negative breast cancer.",[289],"Breast Cancer","2024-06-03",{"date":292,"type":293},"2024-06-04","ACTUAL",{"date":295,"type":293},"2021-01-12",{"date":297,"type":283},"2030-08",{"name":5,"class":6},18]