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Brucker, MD","215-662-9702","Ruoming.Fan@pennmedicine.upenn.edu",{"facility":706,"status":33,"city":707,"state":708,"zip":709,"country":37,"countryCode":38,"cosmosGeoPoint":710,"geoPoint":714,"contacts":715},"Hilton Head Retina Institute","Hilton Head Island","South Carolina","29926",{"type":40,"coordinates":711},[712,713],-80.73816,32.19382,{"lat":713,"lon":712},[716],{"name":717,"role":48,"phone":718,"phoneExt":23,"email":719},"Carl W. Baker, MD","8437152424","jdb@hhretina.com",{"facility":721,"status":33,"city":722,"state":723,"zip":724,"country":37,"countryCode":38,"cosmosGeoPoint":725,"geoPoint":729,"contacts":730},"Ophthalmology Ltd.","Sioux Falls","South Dakota","57108",{"type":40,"coordinates":726},[727,728],-96.72796,43.54369,{"lat":728,"lon":727},[731],{"name":732,"role":48,"phone":733,"phoneExt":23,"email":734},"Elizabeth A. Atchison, MD","6053366294","jweisbrod@opltd.com",{"facility":736,"status":33,"city":737,"state":738,"zip":739,"country":37,"countryCode":38,"cosmosGeoPoint":740,"geoPoint":744,"contacts":745},"Southeastern Retina Associates","Hixson","Tennessee","37343",{"type":40,"coordinates":741},[742,743],-85.23273,35.14063,{"lat":743,"lon":742},[746],{"name":747,"role":48,"phone":748,"phoneExt":23,"email":749},"Francis C. DeCroos, MD","423-756-1002","kschratter@seretina.com",{"facility":751,"status":33,"city":752,"state":738,"zip":753,"country":37,"countryCode":38,"cosmosGeoPoint":754,"geoPoint":758,"contacts":759},"Southeastern Retina Associates, P.C.","Knoxville","37922",{"type":40,"coordinates":755},[756,757],-83.92074,35.96064,{"lat":757,"lon":756},[760],{"name":761,"role":48,"phone":762,"phoneExt":23,"email":763},"R. K. Shuler, Jr., MD","865-588-0811","jwalsh@seretina.com",{"facility":765,"status":33,"city":766,"state":767,"zip":768,"country":37,"countryCode":38,"cosmosGeoPoint":769,"geoPoint":773,"contacts":774},"Austin Research Center for Retina","Austin","Texas","78705",{"type":40,"coordinates":770},[771,772],-97.74306,30.26715,{"lat":772,"lon":771},[775],{"name":776,"role":48,"phone":777,"phoneExt":23,"email":778},"Chirag Jhaveri, MD","737-704-0130","beatris.ramirez@nvisioncenters.com",{"facility":780,"status":33,"city":781,"state":767,"zip":782,"country":37,"countryCode":38,"cosmosGeoPoint":783,"geoPoint":787,"contacts":788},"Retina Consultants of Texas, PA","Bellaire","77401",{"type":40,"coordinates":784},[785,786],-95.45883,29.70579,{"lat":786,"lon":785},[789],{"name":790,"role":48,"phone":791,"phoneExt":23,"email":792},"Charles C. Wykoff, MD, PhD","713-524-3434","ilsa.ortega@retinaconsultantstexas.com",{"facility":794,"status":33,"city":795,"state":767,"zip":796,"country":37,"countryCode":38,"cosmosGeoPoint":797,"geoPoint":801,"contacts":802},"UT Southwestern Medical Center","Dallas","75390",{"type":40,"coordinates":798},[799,800],-96.80667,32.78306,{"lat":800,"lon":799},[803],{"name":804,"role":48,"phone":805,"phoneExt":23,"email":806},"Judy E. Kim, MD","214-645-2012","Juan.Mo@UTSouthwestern.edu",{"facility":808,"status":33,"city":809,"state":767,"zip":810,"country":37,"countryCode":38,"cosmosGeoPoint":811,"geoPoint":815,"contacts":816},"Southwest Retina Consultants","El Paso","79902",{"type":40,"coordinates":812},[813,814],-106.48693,31.75872,{"lat":814,"lon":813},[817],{"name":818,"role":48,"phone":819,"phoneExt":23,"email":820},"Richard Y Hwang, MD","9155323912","ceciliasambrano3@gmail.com",{"facility":822,"status":33,"city":823,"state":767,"zip":824,"country":37,"countryCode":38,"cosmosGeoPoint":825,"geoPoint":829,"contacts":830},"Baylor College of Medicine, Baylor Eye Physicians and Surgeons","Houston","77030-4101",{"type":40,"coordinates":826},[827,828],-95.36327,29.76328,{"lat":828,"lon":827},[831],{"name":832,"role":48,"phone":833,"phoneExt":23,"email":834},"Christina Y. Weng, MD, MBA","713-798-3493","Becky.Chatham@bcm.edu",{"facility":836,"status":33,"city":837,"state":767,"zip":838,"country":37,"countryCode":38,"cosmosGeoPoint":839,"geoPoint":843,"contacts":844},"Texas Retina Associates","Lubbock","79424",{"type":40,"coordinates":840},[841,842],-101.85517,33.57786,{"lat":842,"lon":841},[845],{"name":846,"role":48,"phone":847,"phoneExt":23,"email":848},"Michel Shami, MD","806-792-0066","ysaldivar@texasretina.com",{"facility":850,"status":33,"city":851,"state":767,"zip":852,"country":37,"countryCode":38,"cosmosGeoPoint":853,"geoPoint":857,"contacts":858},"Retina Associates of South Texas","San Antonio","78240",{"type":40,"coordinates":854},[855,856],-98.49363,29.42412,{"lat":856,"lon":855},[859],{"name":860,"role":48,"phone":861,"phoneExt":23,"email":862},"Juan E. Rubio, MD","2106157600","jcervantes@retinastx.com",{"facility":864,"status":33,"city":851,"state":767,"zip":852,"country":37,"countryCode":38,"cosmosGeoPoint":865,"geoPoint":867,"contacts":868},"Retinal Consultants of Texas",{"type":40,"coordinates":866},[855,856],{"lat":856,"lon":855},[869],{"name":870,"role":48,"phone":871,"phoneExt":23,"email":872},"Moises A. Chica, MD","210-615-1311","olivia.gonzales@retinaconsultantstexas.com",{"facility":874,"status":33,"city":875,"state":876,"zip":877,"country":37,"countryCode":38,"cosmosGeoPoint":878,"geoPoint":882,"contacts":883},"The Board of Regents of the University of Wisconsin System","Madison","Wisconsin","53705",{"type":40,"coordinates":879},[880,881],-89.40123,43.07305,{"lat":881,"lon":880},[884],{"name":885,"role":48,"phone":886,"phoneExt":23,"email":887},"Kathleen Schildroth","608-263-7290","kadietzman@wisc.edu",{"facility":889,"status":33,"city":890,"state":876,"zip":891,"country":37,"countryCode":38,"cosmosGeoPoint":892,"geoPoint":896,"contacts":897},"Eye Clinic of Wisconsin","Wausau","54403",{"type":40,"coordinates":893},[894,895],-89.63012,44.95914,{"lat":895,"lon":894},[898],{"name":899,"role":48,"phone":900,"phoneExt":23,"email":901},"Deepak Sambhara, MD","8002618500","ottoser@eyeclinicwi.com",{"facility":903,"status":33,"city":904,"state":905,"zip":906,"country":907,"countryCode":908,"cosmosGeoPoint":23,"geoPoint":23,"contacts":909},"Chow Berger Koushan Medicine Professional Corporation o\u002Fa Toronto Retina Institute","North YORK","Ontario","M3C0G9","Canada","CA",[910],{"name":911,"role":48,"phone":912,"phoneExt":23,"email":913},"Keyvan Koushan","416-449-3937","Mayuri.triresearch@gmail.com",{"facility":915,"status":33,"city":916,"state":905,"zip":917,"country":907,"countryCode":908,"cosmosGeoPoint":918,"geoPoint":922,"contacts":923},"University Health Network","Toronto","M5T 2S8",{"type":40,"coordinates":919},[920,921],-79.39864,43.70643,{"lat":921,"lon":920},[924],{"name":925,"role":48,"phone":926,"phoneExt":23,"email":927},"Michael H. Brent, MD, FRCSC","416-603-5444","Judy.Hung@uhn.ca",{"type":929,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":23,"oldOrganization":23},"SPONSOR",[931,934,936],{"name":932,"class":933},"National Institutes of Health (NIH)","NIH",{"name":935,"class":933},"National Eye Institute (NEI)",{"name":937,"class":6},"Juvenile Diabetes Research Foundation","100508715","phase-3-home-oct-guided-treatment-versus-treat-and-extend-for-the-management-of-neovascular-amd-100508715",false,"NCT05904028","Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD","AO","Key Inclusion Criteria:\n\n* Age ≥ 50 years\n* Have the capacity to consent on his\u002Fher own behalf\n* Able to successfully and independently complete at least one self-scanning session on the Home OCT device located at the enrolling clinical site\n* Willing to perform once daily Home OCT monitoring tests for 2 years without significant interruption (such as travel of more than 14 days)\n* Best corrected E-ETDRS visual acuity ≥24 ETDRS letters (approximately 20\u002F320 or better (Snellen))\n* Previously untreated, active MNV lesion (i.e., any intraretinal or subretinal fluid within the center 3 mm diameter circle on OCT) secondary to age-related macular degeneration\n* ≥ 1 intermediate drusen (≥ 63 microns) in either eye OR late AMD (MNV or macular atrophy) in the contralateral eye\n\nKey Exclusion Criteria for Study Eye:\n\n* Previous treatment for MNV (intravitreal injection of any anti-VEGF or anti-VEGF\u002Fanti-Ang2 agent, or any other AMD therapy)\n* Prior treatment with intravitreal injection of any anti-VEGF or anti-VEGF\u002Fanti-Ang2 agent or with macular laser for any indication\n* Treatment with intravitreal corticosteroids within the last 6 months\n* A condition that, in the opinion of the investigator, would preclude participation in the study or ability to complete daily Home OCT scans for 2 years (e.g., unstable medical status that may preclude successful completion of follow-up, dementia, Alzheimer's disease, uncontrollable tremors)\n* MNV due to other causes, such as ocular histoplasmosis, central serous choroidopathy, or pathologic myopia","ALL","50 Years",{"count":948,"type":949},600,"ESTIMATED","INTERVENTIONAL",[952],"PHASE3","Home optical coherence tomography- guided treatment versus treat and extend for the management of neovascular age-related macular degeneration.",[955],"Neovascular Age-related Macular Degeneration",[957],"optical coherence tomography","2026-05-15",{"date":960,"type":961},"2026-05-18","ACTUAL",{"date":963,"type":961},"2023-11-09",{"date":965,"type":949},"2027-07-30",{"name":5,"class":6},65]