[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100642249":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":30,"locations":36,"responsibleParty":50,"collaborators":26,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":58,"acronym":26,"eligibilityCriteria":59,"healthyVolunteers":56,"sex":60,"minAge":61,"maxAge":26,"enrollmentInfo":62,"targetDuration":26,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":73,"whyStopped":26,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Atlantic Health System","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Emergency Department Vancomycin Powder","EXPERIMENTAL","Patients receive 1 gram topical vancomycin powder applied to the open fracture wound in the Emergency Department in addition to standard open fracture management.",[13],"Drug: Vancomycin (VAN) treatment",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard Open Fracture Care","ACTIVE_COMPARATOR","Patients receive standard open fracture management without Emergency Department (ED) vancomycin powder.",[19],"Other: Standard Open Fracture Care",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Vancomycin (VAN) treatment","A single 1-gram dose of sterile vancomycin powder is applied directly to the open fracture wound in the Emergency Department after initial wound assessment and irrigation and prior to definitive operative debridement and fixation.",[9],null,{"type":6,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"Standard management of open fractures according to institutional protocols, including intravenous antibiotics, wound care, irrigation, operative debridement, and fracture stabilization as indicated, without topical vancomycin powder application in the Emergency Department.",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":26,"email":35},"Kristen De Wilde MD","CONTACT","201-572-9087","kristen.dewilde@atlantichealth.org",[37],{"facility":38,"status":26,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":26},"Morristown Medical Center","Morristown","New Jersey","07930","United States","US",{"type":45,"coordinates":46},"Point",[47,48],-74.48154,40.79677,{"lat":48,"lon":47},{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Kristen De Wilde","Resident physician","100642249","phase-3-implementation-of-vancomycin-powder-application-in-the-emergency-department-for-open-fractures-100642249",false,"NCT07659886","Implementation of Vancomycin Powder Application in the Emergency Department for Open Fractures","Inclusion Criteria:\n\n* Participants aged 18 years or older presenting to the Emergency Department with Gustilo-Anderson Type I, II, or III open fractures.\n\nExclusion Criteria:\n\n* Known allergy to vancomycin\n* Ballistic open fractures\n* Pregnancy\n* Currently breastfeeding\n* Age younger than 18 years.","ALL","18 Years",{"count":63,"type":64},100,"ESTIMATED","INTERVENTIONAL",[67],"PHASE3","To evaluate the feasibility, safety, and potential efficacy of applying vancomycin powder locally to open fractures in the emergency department prior to definitive surgical intervention.",[70],"Open Fracture",[72],"open fracture","NOT_YET_RECRUITING","2026-06-17",{"date":76,"type":77},"2026-06-22","ACTUAL",{"date":79,"type":64},"2026-06-10",{"date":81,"type":64},"2027-06-10",{"name":5,"class":6},1]