[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100486954":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":33,"locations":39,"responsibleParty":60,"collaborators":18,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":18,"eligibilityCriteria":69,"healthyVolunteers":70,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":18,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":18,"overallStatus":41,"whyStopped":18,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Northwestern University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Loop Diuretic (Furosemide)","EXPERIMENTAL","This group of patients will receive 20mg of IV furosemide during the morcellation phase of their HoLEP.",[13],"Drug: Furosemide",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","NO_INTERVENTION","This group of patients will not receive 20mg of IV furosemide during the morcellation phase of their HoLEP.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Furosemide","20mg of IV furosemide injection during the morcellation phase of HoLEP",[9],[26,27],"Lasix","Loop diuretic",[29],{"name":30,"affiliation":31,"role":32},"Amy E Krambeck, MD","Northwestern Medicine","PRINCIPAL_INVESTIGATOR",[34],{"name":35,"role":36,"phone":37,"phoneExt":18,"email":38},"Nicholas S Dean, MD","CONTACT","7806906285","nicholas.dean@northwestern.edu",[40],{"facility":5,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"RECRUITING","Chicago","Illinois","60611","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-87.65005,41.85003,{"lat":51,"lon":50},[54,57],{"name":55,"role":36,"phone":18,"phoneExt":18,"email":56},"Nicholas Dean, MD","nicholas.dean@nm.org",{"name":58,"role":36,"phone":18,"phoneExt":18,"email":59},"Alyssa McDonald","alyssa.mcdonald@northwestern.edu",{"type":32,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Amy Krambeck","Director of The Division of Endourology & Stone Disease","100486954","phase-3-intra-operative-loop-diuretics-to-improve-same-day-discharge-rates-after-holep-100486954",false,"NCT05620784","Intra-operative Loop Diuretics to Improve Same-day Discharge Rates After HoLEP","Loop Diuretics During Morcellation to Improve Same-day Discharge Rates After Holmium Laser Enucleation of the Prostate (HoLEP)","Inclusion Criteria:\n\n* Males 18 -89 undergoing HoLEP\n* Willing to sign the Informed Consent Form\n* Able to read, understand, and complete patient questionnaires.\n\nExclusion Criteria:\n\n* Allergy or hypersensitivity to furosemide or other loop diuretic\n* Anuric patients or patients with liver failure\n* Patients having a concurrent ureteroscopy +\u002F- laser lithotripsy, percutaneous nephrolithotomy, or non-urologic surgery at the time of their HoLEP\n* Anticipated need for perineal urethrostomy at the time of HoLEP\n* Patient not undergoing catheter removal and voiding trial at Northwestern Memorial Hospital",true,"MALE","18 Years","89 Years",{"count":75,"type":76},138,"ESTIMATED","INTERVENTIONAL",[79],"PHASE3","Holmium Laser Enucleation of the Prostate (HoLEP) is a size-independent treatment option for benign prostatic hypertrophy (BPH) as recommended by the American Urological Association (AUA) Guidelines. Loop diuretics (furosemide) have been given historically during the morcellation portion of HoLEP to promote urine production in the post-operative setting and to minimize the impact of fluid absorption during long periods of morcellation. The intra-operative use of 20mg IV furosemide in perioperative HoLEP pathways has been propagated with the dissemination of HoLEP across North America without evidence to support its routine administration. With increasing surgical efficiency from improvements in laser and morcellator technology, the role of intra-operative furosemide is unknown. This study is designed to assess if there is a significant difference in same day discharge rates after Holmium Laser Enucleation of the Prostate (HoLEP) with and without IV furosemide. .",[82,83,84,85],"BPH With Urinary Obstruction","BPH","Hematuria","Same Day Discharge","2023-09-11",{"date":88,"type":89},"2023-09-13","ACTUAL",{"date":91,"type":89},"2023-03-01",{"date":93,"type":76},"2024-08-01",{"name":5,"class":6},1]