[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100594284":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":56,"collaborators":26,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":26,"eligibilityCriteria":64,"healthyVolunteers":65,"sex":66,"minAge":67,"maxAge":26,"enrollmentInfo":68,"targetDuration":26,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":26,"overallStatus":77,"whyStopped":26,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"University of Manitoba","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Mirabegron post procedure","EXPERIMENTAL","In this arm, patients will receive a 30 day prescription of mirabegron post-procedure.",[13],"Drug: Beta-3 agonists (Mirabegron\u002FMyrbetriq)",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo pill post rezum","SHAM_COMPARATOR","Patients in this arm will be given the placebo pill following their procedure.",[19],"Other: Placebo group post rezum",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Beta-3 agonists (Mirabegron\u002FMyrbetriq)","Patients in this arm will receive the medication in pill form following their procedure",[9],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Placebo group post rezum","Patients in this arm will receive the placebo pill following their procedure.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Premal Patel, MD","CONTACT","204-221-4476","ppatel5@hsc.mb.ca",[38],{"facility":39,"status":26,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Men's Health Clinic Manitoba","Winnipeg","Manitoba","R3P 2S8","Canada","CA",{"type":46,"coordinates":47},"Point",[48,49],-97.14704,49.8844,{"lat":49,"lon":48},[52,54],{"name":53,"role":34,"phone":35,"phoneExt":26,"email":36},"Preal Patel, MD",{"name":33,"role":55,"phone":26,"phoneExt":26,"email":26},"PRINCIPAL_INVESTIGATOR",{"type":55,"investigatorFullName":33,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Assistant Professor, Department of Surgery. Director, Undergraduate Urologic Medical Education","100594284","phase-3-investigating-the-adjunctive-use-of-mirabegron-in-the-early-post-rezum-procedure-period-100594284",false,"NCT07017439","Investigating the Adjunctive Use of Mirabegron in the Early Post-Rezum Procedure Period","Investigating the Adjunctive Use of B3-agonist in the Early Post-Rezum Procedure Period: A Randomized Controlled Trial","Inclusion Criteria:\n\n* age \\>50, symptomatic LUTS with IPSS ≥ 10\n* prostate volume 30-80cc on any imaging modality\n* Qmax between 5 and 15ml\u002Fs with minimum voided volume of 125cc\n* frequency ≥ 8 voids\u002Fday.\n\nExclusion Criteria:\n\n* PVR greater than 300ml\n* active UTI within past week\n* previous surgical intervention for BPH\n* documented urethral stricture disease\n* bladder stones\n* active malignancy\n* any confirmed or suspected neurologic disease\n* hypertension\n* known insensitivity to B3 agonist\n* current catheter dependence\n* currently taking anticholinergic or B3 agonist.",true,"MALE","50 Years",{"count":69,"type":70},50,"ESTIMATED","INTERVENTIONAL",[73],"PHASE3","The investigators propose conducting a randomized controlled trial at the Men's Health Clinic to evaluate whether patients who start and continue mirabegron postoperatively after undergoing Rezum therapy experience enhanced patient-reported outcomes, improved quality of life (QoL), and comparable rates of adverse events. There are no predicted adverse events of this study. There are no identified potential harms of this study.",[76],"Benign Prostate Hypertrophy(BPH)","NOT_YET_RECRUITING","2025-06-11",{"date":80,"type":81},"2025-06-12","ACTUAL",{"date":83,"type":70},"2025-08",{"date":85,"type":70},"2026-06",{"name":5,"class":6},1]