[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100574862":3},{"organization":4,"armGroups":7,"interventions":31,"overallOfficials":50,"centralContacts":54,"locations":64,"responsibleParty":94,"collaborators":97,"id":103,"slug":104,"hasResults":105,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":109,"eligibilityCriteria":110,"healthyVolunteers":105,"sex":111,"minAge":112,"maxAge":37,"enrollmentInfo":113,"targetDuration":37,"studyType":116,"phases":117,"briefSummary":119,"conditions":120,"keywords":123,"overallStatus":67,"whyStopped":37,"lastUpdateSubmitDate":126,"lastUpdatePostDateStruct":127,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":135},{"fullName":5,"class":6},"King Saud University","OTHER",[8,14,20,25],{"label":9,"type":10,"description":11,"interventionNames":12},"anodal tDCS combined with VRMT","EXPERIMENTAL","20 minutes of anodal tDCS combined with 45 minutes of VRMT",[13],"Device: Transcranial Direct Current Stimulation compined with virtual reality based mirror therapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Anodal tDCS alone","ACTIVE_COMPARATOR","20 minutes of anodal tDCS alone",[19],"Device: Transcranial Direct Current Stimulation",{"label":21,"type":16,"description":22,"interventionNames":23},"VRMT alone, Sham tDCS","45 minutes of VRMT alone, For the sham-tDCS, the current flow will be terminated after 30 seconds.",[24],"Device: Virtual reality",{"label":26,"type":27,"description":28,"interventionNames":29},"Conventional Physical therapy alone, Sham tDCS","SHAM_COMPARATOR","45 minutes of conventional physical therapy, For the sham-tDCS, the current flow will be terminated after 30 seconds.",[30],"Other: Conventional physical therapy",[32,38,42,46],{"type":33,"name":34,"description":35,"armGroupLabels":36,"otherNames":37},"DEVICE","Transcranial Direct Current Stimulation","tDCS will be used during the sessions. The anodal tDCS (2 mA) will be applied for 20 minutes. Continuous, direct currents. The anodal electrode will be positioned over the ipsilesional primary motor cortex (M1) (C3 or C4, international 10-20 system) of the affected hemisphere and the cathodal electrode over the contralateral orbit.",[15],null,{"type":33,"name":39,"description":40,"armGroupLabels":41,"otherNames":37},"Virtual reality","The VRMT group will receive VRMT game-based training using their non-affected upper limb. using a semi-immersive motion-tracking device.",[21],{"type":33,"name":43,"description":44,"armGroupLabels":45,"otherNames":37},"Transcranial Direct Current Stimulation compined with virtual reality based mirror therapy","20 minutes of tDCS during 45 minutes of VRMT games.",[9],{"type":6,"name":47,"description":48,"armGroupLabels":49,"otherNames":37},"Conventional physical therapy","45 minutes of conventional physical therapy with sham tDCS",[26],[51],{"name":52,"affiliation":5,"role":53},"Alaa M. Albishi, Doctor of Philosophy","PRINCIPAL_INVESTIGATOR",[55,60],{"name":56,"role":57,"phone":58,"phoneExt":37,"email":59},"Dr. Alaa M. Albishi, Assistant Professor","CONTACT","+966555090015","aalbeshi@ksu.edu.sa",{"name":61,"role":57,"phone":62,"phoneExt":37,"email":63},"Dr. Ahmad O Alokaily, Assistant Professor","+966557447442","aalokaily@ksu.edu.sa",[65,84],{"facility":66,"status":67,"city":68,"state":69,"zip":70,"country":71,"countryCode":72,"cosmosGeoPoint":73,"geoPoint":78,"contacts":79},"King fahad medical city","RECRUITING","Riyadh","Riyadh Region","11461","Saudi Arabia","SA",{"type":74,"coordinates":75},"Point",[76,77],46.72185,24.68773,{"lat":77,"lon":76},[80],{"name":81,"role":57,"phone":82,"phoneExt":37,"email":83},"Dr. Fahad alsubaie alsubaie, Phd","+966554728899","falsubaie@kfmc.med.sa",{"facility":85,"status":67,"city":68,"state":69,"zip":70,"country":71,"countryCode":72,"cosmosGeoPoint":86,"geoPoint":88,"contacts":89},"King Khalid University Hospital",{"type":74,"coordinates":87},[76,77],{"lat":77,"lon":76},[90],{"name":91,"role":57,"phone":92,"phoneExt":37,"email":93},"Dr. Taha Inam Dr. Taha Inam, Phd","+966548083373","dr_taha_inam@hotmail.com",{"type":53,"investigatorFullName":95,"investigatorTitle":96,"investigatorAffiliation":5,"oldNameTitle":37,"oldOrganization":37},"Dr. Alaa Albishi","Associate professor",[98,101],{"name":99,"class":100},"King Fahad Medical City","OTHER_GOV",{"name":102,"class":100},"King Saud Medical City","100574862","phase-3-investigating-the-efficacy-of-combining-virtual-reality-based-mirror-therapy-vrmt-and-transcranial-direct-current-stimulation-tdcs-to-improve-upper-limb-recovery-in-patients-with-stroke-100574862",false,"NCT06764797","Investigating the Efficacy of Combining Virtual Reality-Based Mirror Therapy (VRMT) and Transcranial Direct Current Stimulation (tDCS) to Improve Upper Limb Recovery in Patients with Stroke","Investigating the Efficacy of Combining Virtual Reality-Based Mirror Therapy and Transcranial Direct Current Stimulation to Improve Upper Limb Recovery in Patients with Stroke","tDCS","Inclusion Criteria:\n\n* At least 18 years old.\n* Stroke patients with unilateral cerebral infarction or hemorrhage, more than three months following the stroke.\n* Adequate cognitive ability to follow instructions (The Arabic version of the Mini-Mental State Examination scores \\> 24).\n* Modified Ashworth scale score \\\u003C 3.\n* Fugl-Meyer Assessment (FMA) score of 10-58 indicating moderate-to-severe arm impairment.\n\nExclusion Criteria:\n\n* visual impairment and field defect or hemi-sensory inattention and unilateral neglect.\n* Wernicke's aphasia, or global aphasia, leads to difficulty following instructions.\n* Any contraindication to NIBS.\n* Other neurological conditions or participation in another study.","ALL","18 Years",{"count":114,"type":115},300,"ESTIMATED","INTERVENTIONAL",[118],"PHASE3","This study will investigate whether combining virtual reality-based mirror therapy (VRMT) and transcranial direct current stimulation (tDCS) alongside conventional physical therapy (CPT) will significantly improve hand function for patients with stroke compared to using VRMT or tDCS alone.",[121,122],"Stroke Rehabilitaion","Stroke",[124,125],"Virtual reality, Mirror therapy, non invasive brain stimulation, tDCS, stroke","transcranial direct current stimulation","2025-01-02",{"date":128,"type":129},"2025-01-08","ACTUAL",{"date":131,"type":129},"2023-09-19",{"date":133,"type":115},"2025-07-21",{"name":5,"class":6},2]