[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586043":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":11,"locations":27,"responsibleParty":48,"collaborators":50,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":57,"acronym":11,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":60,"minAge":61,"maxAge":11,"enrollmentInfo":62,"targetDuration":11,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":11,"overallStatus":30,"whyStopped":11,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Florida Atlantic University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Lidocaine","ACTIVE_COMPARATOR",null,[13],"Drug: Lidocaine",{"label":15,"type":16,"description":11,"interventionNames":17},"Diphenhydramine","EXPERIMENTAL",[18],"Drug: Diphenhydramine",[20,24],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":11},"DRUG","Lidocaine local infiltration",[9],{"type":21,"name":15,"description":25,"armGroupLabels":26,"otherNames":11},"Diphenhydramine local infiltration",[15],[28],{"facility":29,"status":30,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Bethesda Hospital East","RECRUITING","Boynton Beach","Florida","33435","United States","US",{"type":37,"coordinates":38},"Point",[39,40],-80.06643,26.52535,{"lat":40,"lon":39},[43],{"name":44,"role":45,"phone":46,"phoneExt":11,"email":47},"Scott M Alter, MD","CONTACT","561-733-5933","alters@health.fau.edu",{"type":49,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR",[51],{"name":52,"class":6},"Baptist Health South Florida","100586043","phase-3-lidocaine-versus-diphenhydramine-to-achieve-local-anesthesia-for-laceration-repairs-100586043",false,"NCT06910241","Lidocaine Versus Diphenhydramine to Achieve Local Anesthesia for Laceration Repairs","Inclusion Criteria:\n\n* Lacerations requiring one layer of sutures\n* Lacerations appropriate for repair by emergency physicians\n\nExclusion Criteria:\n\n* Active bleeding from laceration\n* Complex lacerations requiring multiple layers\n* Lacerations to be repaired by a specialist service\n* Patients with allergies to either diphenhydramine or lidocaine\n* Laceration repairs would benefit from the use of epinephrine as an additive to the local anesthetic",true,"ALL","18 Years",{"count":63,"type":64},100,"ESTIMATED","INTERVENTIONAL",[67],"PHASE3","Diphenhydramine, when injected locally, has been shown to achieve a certain level of local anesthesia. It has been documented for use in simple bedside procedures, however there is a gap in knowledge in its comparison to lidocaine. The purpose of the study is to determine if local infiltration of diphenhydramine is noninferior to the use of lidocaine 1% when trying to achieve local anesthesia for simple laceration repair. Patients who present to the emergency department with a simple laceration will be enrolled in the study. Patients will be evaluated for the pain of the injection as well as the pain of the laceration repair procedure post injection.",[70],"Laceration of Skin","2026-01-06",{"date":73,"type":74},"2026-01-07","ACTUAL",{"date":76,"type":74},"2025-09-03",{"date":78,"type":64},"2028-06-30",{"name":5,"class":6},1]