[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100211102":3},{"organization":4,"armGroups":7,"interventions":29,"overallOfficials":52,"centralContacts":57,"locations":67,"responsibleParty":84,"collaborators":47,"id":87,"slug":88,"hasResults":89,"nctId":90,"briefTitle":91,"officialTitle":91,"acronym":92,"eligibilityCriteria":93,"healthyVolunteers":89,"sex":94,"minAge":95,"maxAge":47,"enrollmentInfo":96,"targetDuration":47,"studyType":99,"phases":100,"briefSummary":102,"conditions":103,"keywords":105,"overallStatus":70,"whyStopped":47,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":120},{"fullName":5,"class":6},"University of Washington","OTHER",[8,14,19,24],{"label":9,"type":10,"description":11,"interventionNames":12},"Incision and Curettage","ACTIVE_COMPARATOR","A vertical incision over the area of chalazion will be done. Inflammatory material will be removed and the chalazion capsule will be excised.",[13],"Procedure: Incision and Curettage",{"label":15,"type":10,"description":16,"interventionNames":17},"Injection of Triamcinolone Acetonide","0.1 ml of triamcinolone is injected directly in the chalazion.",[18,13],"Drug: Triamcinolone Acetonide",{"label":20,"type":10,"description":21,"interventionNames":22},"Injection of 5-fluorouracil","0.1 ml of 5-fluorouracil is injected directly in the lesion transconjunctivally.",[23,13],"Drug: 5-fluorouracil Injection",{"label":25,"type":10,"description":26,"interventionNames":27},"Injection of triamcinolone\u002F5FU mixture","0.1 ml of a 4:1 mixture of 4 parts 5-FU and 1 part triamcinolone is injected in the lesion.",[13,28],"Drug: Triamcinolone Acetonide\u002F5-fluorouracil mixture",[30,37,43,48],{"type":31,"name":32,"description":33,"armGroupLabels":34,"otherNames":35},"DRUG","5-fluorouracil Injection","If the chalazion is present at follow-up visit, another injection of 5-FU will be given.",[20],[36],"5-FU",{"type":31,"name":38,"description":39,"armGroupLabels":40,"otherNames":41},"Triamcinolone Acetonide","If chalazion present at follow-up, another Triamcinolone injection will be done.",[15],[42],"triamcinolone",{"type":44,"name":9,"description":45,"armGroupLabels":46,"otherNames":47},"PROCEDURE","If chalazion present at follow-up visit, patient will be randomized to receive local injection of either triamcinolone, 5-FU, or triamcinolone\u002F5-FU mixture.",[9,20,15,25],null,{"type":31,"name":49,"description":50,"armGroupLabels":51,"otherNames":47},"Triamcinolone Acetonide\u002F5-fluorouracil mixture","If chalazion persists at follow-up visit, another injection of triamcinolone\u002F5-FU mixture will be done.",[25],[53],{"name":54,"affiliation":55,"role":56},"Matthew M Zhang, MD","University of Washington Eye Institute","PRINCIPAL_INVESTIGATOR",[58,63],{"name":59,"role":60,"phone":61,"phoneExt":47,"email":62},"Simona Vuletic","CONTACT","206-520-9728","simona@uw.edu",{"name":64,"role":60,"phone":65,"phoneExt":47,"email":66},"Ian Luttrell","206-520-8305","lutri@uw.edu",[68],{"facility":69,"status":70,"city":71,"state":72,"zip":73,"country":74,"countryCode":75,"cosmosGeoPoint":76,"geoPoint":81,"contacts":82},"University of Washington Eye Institute at Harborview","RECRUITING","Seattle","Washington","98104","United States","US",{"type":77,"coordinates":78},"Point",[79,80],-122.33207,47.60621,{"lat":80,"lon":79},[83],{"name":59,"role":60,"phone":61,"phoneExt":47,"email":62},{"type":56,"investigatorFullName":85,"investigatorTitle":86,"investigatorAffiliation":5,"oldNameTitle":47,"oldOrganization":47},"Matthew Zhang","Assistant Professor of Ophthalmology","100211102","phase-3-local-5-fluorouracil-injection-for-the-treatment-of-chalazia-a-prospective-comparative-study-100211102",false,"NCT02025023","Local 5-Fluorouracil Injection for the Treatment of Chalazia: A Prospective, Comparative Study","CTS","Inclusion Criteria:\n\n* Single or multiple chalazia in a single eyelid\n\nExclusion Criteria:\n\n* Chalazia present for less than one month and no previous injection or incision and curettage","ALL","18 Years",{"count":97,"type":98},120,"ESTIMATED","INTERVENTIONAL",[101],"PHASE3","Local injection of 5-fluorouracil into a chalazion (stye) is as effective as local injection of triamcinolone (steroid) and incision and curettage for treatment of chalazia.",[104],"Chalazion",[106,107,108,109,110],"Size","Pain","Resolution","Complications","Swelling","2020-02-04",{"date":113,"type":114},"2020-02-06","ACTUAL",{"date":116,"type":47},"2013-12",{"date":118,"type":98},"2026-07",{"name":5,"class":6},1]