[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100578350":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":12,"centralContacts":24,"locations":30,"responsibleParty":86,"collaborators":12,"id":90,"slug":91,"hasResults":92,"nctId":93,"briefTitle":94,"officialTitle":95,"acronym":12,"eligibilityCriteria":96,"healthyVolunteers":92,"sex":97,"minAge":98,"maxAge":99,"enrollmentInfo":100,"targetDuration":12,"studyType":103,"phases":104,"briefSummary":106,"conditions":107,"keywords":109,"overallStatus":113,"whyStopped":12,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":123},{"fullName":5,"class":6},"University of Calgary","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Control","NO_INTERVENTION","Infants will not receive any probiotics.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Multi-strain probiotics","EXPERIMENTAL","Infants will be started on probiotics (Bifidobacterium and Lacticaseibacillus) within 24 hours of commencing enteral feeds.",[18],"Biological: Multi-strain probiotics",[20],{"type":21,"name":14,"description":22,"armGroupLabels":23,"otherNames":12},"BIOLOGICAL","Infants will be started on probiotics (Bifidobacterium and Lacticaseibacillus) with enetral feed.",[14],[25],{"name":26,"role":27,"phone":28,"phoneExt":12,"email":29},"Belal N Alshaikh, MD, MSc","CONTACT","+1 403 956 1588","balshaik@ucalgary.ca",[31,46,59,73],{"facility":32,"status":12,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Foothills Medical Center","Calgary","Alberta","T2Z 2G9","Canada","CA",{"type":39,"coordinates":40},"Point",[41,42],-114.08529,51.05011,{"lat":42,"lon":41},[45],{"name":26,"role":27,"phone":28,"phoneExt":12,"email":29},{"facility":47,"status":12,"city":48,"state":34,"zip":12,"country":36,"countryCode":37,"cosmosGeoPoint":49,"geoPoint":53,"contacts":54},"Royal Alexandra Hospital","Edmonton",{"type":39,"coordinates":50},[51,52],-113.46871,53.55014,{"lat":52,"lon":51},[55],{"name":56,"role":27,"phone":57,"phoneExt":12,"email":58},"Kumar Kumaran, MD","780-735-5179","kumar.kumaran@ahs.ca",{"facility":60,"status":12,"city":61,"state":62,"zip":12,"country":36,"countryCode":37,"cosmosGeoPoint":63,"geoPoint":67,"contacts":68},"Children's and Women's health of Britch Columbia","Vancouver","British Columbia",{"type":39,"coordinates":64},[65,66],-123.11934,49.24966,{"lat":66,"lon":65},[69],{"name":70,"role":27,"phone":71,"phoneExt":12,"email":72},"Horacio Osiovich, MD","604- 875-2345","hosiovich@cw.bc.ca",{"facility":74,"status":12,"city":75,"state":12,"zip":12,"country":36,"countryCode":37,"cosmosGeoPoint":76,"geoPoint":80,"contacts":81},"IWK","Halifax",{"type":39,"coordinates":77},[78,79],-63.57688,44.64269,{"lat":79,"lon":78},[82],{"name":83,"role":27,"phone":84,"phoneExt":12,"email":85},"Balpreet Singh, MD","902-470-7055","balpreet.singh@iwk.nshealth.ca",{"type":87,"investigatorFullName":88,"investigatorTitle":89,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"PRINCIPAL_INVESTIGATOR","Belal Alshaikh","Principle investigator","100578350","phase-3-multi-strain-probiotics-to-prevent-necrotizing-enterocolitis-in-very-preterm-infants-100578350",false,"NCT06810154","Multi-strain Probiotics to Prevent Necrotizing Enterocolitis in Very Preterm Infants","Multi-strain Probiotics to Prevent Necrotizing Enterocolitis in Very Preterm Infants: a Stepped-Wedge Cluster Randomized Trial","Inclusion Criteria:\n\n* Infants born between \\\u003C32 0\u002F7 weeks gestation.\n\nExclusion Criteria:\n\n* Major congenital or chromosomal abnormalities\n* Conditions affecting gastrointestinal systems that prohibit infants from starting on feed in the first 72 hours after birth.","ALL","0 Hours","72 Hours",{"count":101,"type":102},2170,"ESTIMATED","INTERVENTIONAL",[105],"PHASE3","The goal of this clinical trial is to evaluate whether multi-strain probiotics of lactobacillus and bifidobacterium can prevent necrotizing enterocolitis (NEC) in preterm infants born at less than 32 weeks of gestation. The main questions it aims to answer are:\n\n* Does the use of a multi-strain probiotic combination reduce the incidence of NEC in preterm infants?\n* Are there any adverse effects associated with the administration of this probiotic combination?",[108],"Necrotizing Enterocolitis (NEC)",[110,111,112],"Probiotics","Necrotizing enteroclitis","preterm infants","NOT_YET_RECRUITING","2025-01-30",{"date":116,"type":117},"2025-02-05","ACTUAL",{"date":119,"type":102},"2025-06-01",{"date":121,"type":102},"2028-05-30",{"name":5,"class":6},4]